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公开(公告)号：US20090081081A1
公开(公告)日：2009-03-26
申请号：US12203720
申请日：2008-09-03
申请人： Takeo KOWARI , Takayoshi Izumi
发明人： Takeo KOWARI , Takayoshi Izumi
CPC分类号： G01N35/10 , B01L3/0275 , B01L9/543 , G01N2035/0453 , G01N2035/0465 , G01N2035/103
摘要： The present invention is to present a pipette tip supplier and a sample analyzer which are capable of increasing an efficiency of eliminating electrification charge of the pipette tip than ever before. The pipette tip supplier comprises: a tip supply mechanism section 32 for containing pipette tips 3; a tip storing section 34 for storing pipette tips 3 supplied from the tip supply mechanism section 32; a static eliminator fan 33 for performing an eliminating operation for eliminating electrification charge of the pipette tips 3 being stored in the tip storing section 34; and a separating mechanism section 36 for performing a separating operation for separating the pipette tips 3 being stored in the tip storing section 34 one by one.
摘要翻译： 本发明提供一种能够提高除去移液器吸头的带电电荷的效率的移液管尖端供给器和样品分析装置。 移液管末端供应器包括：用于容纳移液管吸头3的末端供给机构部分32; 尖端存储部分34，用于存储从尖端供应机构部分32提供的移液管尖端3; 静电消除器风扇33，用于执行消除操作，以消除存储在尖端存储部分34中的移液管吸头3的带电电荷; 以及分离机构部分36，用于逐个进行分离存储在尖端存储部分34中的移液管吸头3的分离操作。
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2.发明授权公开(公告)号：US08105535B2
公开(公告)日：2012-01-31
申请号：US12212008
申请日：2008-09-17
申请人： Takeo Kowari , Takayoshi Izumi
发明人： Takeo Kowari , Takayoshi Izumi
CPC分类号： G01N35/04 , G01N35/1011 , G01N2035/1013 , G01N2035/103 , Y10T436/110833 , Y10T436/113332 , Y10T436/2575
摘要： The present invention is to present a pipette tip supplier which is capable of convey the pipette tip smoothly. The pipette tip supplier 30 comprises: container 31 for containing pipette tips 3; separator 36 for separating pipette tips one by one; transporting section 37 for transporting pipette tips separated by the separator 36, one by one, to a first position via a second position and for dropping the transported pipette tips from the first position, the pipette tips transported by the transporting section 37 comprising a preceding pipette tip and a following pipette tip transported after the preceding pipette tip; detector 40e for detecting the following pipette tip at the second position before the following pipette tip arrives at the first position; and controller 2a for controlling the transporting section 37 so as to suspend transporting operation when the detector 40e detects the following pipette tip at the second position.
摘要翻译： 本发明提供一种能够平稳地输送移液管吸头的吸头提示供给器。 移液管尖端供应器30包括：用于容纳移液管吸头3的容器31; 分离器36，用于逐个分离移液管吸头; 运送部分37，用于将通过分离器36分离的移液管尖端一个接一个地经由第二位置运送到第一位置，并且用于从第一位置运送运送的移液管末端，由运送部分37运送的移液管末端包括一个先前的移液管 尖端和在之前的移液管尖端之后运送的以下移液管尖端; 检测器40e，用于在所述第二位置之前检测下一移液管尖端，在所述第二位置之前，所述第二位置在所述第一位置之前到达所述第二位置; 以及控制器2a，用于控制传送部37，以便当检测器40e在第二位置检测到以下移液管尖端时暂停传送操作。
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3.发明申请公开(公告)号：US20090078717A1
公开(公告)日：2009-03-26
申请号：US12212008
申请日：2008-09-17
申请人： Takeo Kowari , Takayoshi Izumi
发明人： Takeo Kowari , Takayoshi Izumi
CPC分类号： G01N35/04 , G01N35/1011 , G01N2035/1013 , G01N2035/103 , Y10T436/110833 , Y10T436/113332 , Y10T436/2575
摘要： The present invention is to present a pipette tip supplier which is capable of convey the pipette tip smoothly. The pipette tip supplier 30 comprises: container 31 for containing pipette tips 3; separator 36 for separating pipette tips one by one; transporting section 37 for transporting pipette tips separated by the separator 36, one by one, to a first position via a second position and for dropping the transported pipette tips from the first position, the pipette tips transported by the transporting section 37 comprising a preceding pipette tip and a following pipette tip transported after the preceding pipette tip; detector 40e for detecting the following pipette tip at the second position before the following pipette tip arrives at the first position; and controller 2a for controlling the transporting section 37 so as to suspend transporting operation when the detector 40e detects the following pipette tip at the second position.
摘要翻译： 本发明提供一种能够平稳地输送移液管吸头的吸头提示供给器。 移液管尖端供应器30包括：用于容纳移液管吸头3的容器31; 分离器36，用于逐个分离移液管吸头; 运送部分37，用于将通过分离器36分离的移液管尖端一个接一个地经由第二位置运送到第一位置，并且用于从第一位置运送运送的移液管末端，由运送部分37运送的移液管末端包括一个先前的移液管 尖端和在之前的移液管尖端之后运送的以下移液管尖端; 检测器40e，用于在所述第二位置之前检测下一移液管尖端，在所述第二位置之前，所述第二位置在所述第一位置之前到达所述第二位置; 以及控制器2a，用于控制传送部37，以便当检测器40e在第二位置检测到以下移液管尖端时暂停传送操作。
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公开(公告)号：US5384093A
公开(公告)日：1995-01-24
申请号：US35400
申请日：1993-03-23
申请人： Toshihiro Ootani , Takayoshi Izumi
发明人： Toshihiro Ootani , Takayoshi Izumi
CPC分类号： G01N35/109 , G01N35/0092 , G01N2035/0093 , G01N2035/0484 , G01N35/028 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998
摘要： An apparatus for aspirating and discharging a specific volume of liquid sample, such as specimen and reagent, has a reaction plate serving a holding function and having a plurality of reaction containers, is provided which is low in cost and compact in design. On one side of a belt applied on two pulleys driven by one driving source an arm for holding a pipet is provided, while a reaction plate holding part is mounted on the other side of the belt (112), thereby constructing an apparatus for aspirating and discharging a liquid sample. When the arm ascends, the holding part descends, and when the arm descends, the holding part ascends. Thus, the arm and holding part are moved mutually in opposite directions by one driving source.
摘要翻译： 用于抽吸和排出诸如试样和试剂的特定体积的液体样品的装置具有一种具有保持功能的反应板，并具有多个反应容器，成本低，设计紧凑。 在由一个驱动源驱动的两个滑轮上的带的一侧上设置有用于保持移液管的臂，而反作用板保持部安装在皮带（112）的另一侧，从而构成一个吸引和 排出液体样品。 当臂上升时，保持部下降，当臂下降时，保持部上升。 因此，臂和保持部通过一个驱动源在相反的方向上相互移动。
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公开(公告)号：US5501838A
公开(公告)日：1996-03-26
申请号：US367824
申请日：1995-01-03
申请人： Toshihiro Ootani , Takayoshi Izumi
发明人： Toshihiro Ootani , Takayoshi Izumi
CPC分类号： B01L3/5085 , G01N35/0092 , G01N35/0095 , G01N35/028 , G01N2035/00356 , G01N2035/00435 , G01N2035/00524 , G01N2035/0093 , G01N2035/0425 , G01N35/026 , G01N35/109 , Y10T436/11 , Y10T436/113332 , Y10T436/114998 , Y10T436/115831 , Y10T436/12 , Y10T436/25 , Y10T436/2575
摘要： A small, inexpensive, and easy-to-use automated immunochemical anlayzer is provided. The automated immunochemical analyzer comprises at least one reaction plate of disposable type forming a plurality of containers in one body, a table that can be drawn out for mounting the reaction plates, a table can be drawn out for mounting specimen racks, a reagent thermostatic unit, a reaction thermostatic unit, a reaction plate holding part, an apparatus for aspirating and discharging sample liquid, and an XY moving part mounting the reaction plate holding part and the apparatus for aspirating and discharging sample liquid. First, by the XY moving part, the holding part holds the reaction plate before use from the table for mounting the reaction plates and moves up to the reaction thermostats unit. Consequently, by the XY moving part, the apparatus for aspirating and discharging sample liquid is moved reciprocally among the specimen rack, reagent thermostatic unit, and reaction thermostatic unit, thereby distributing specimens and reagents to the reaction plate. THe distributed liquid is kept in a thermostatic state, and shaken and agitated, thereby promoting the antigen-antibody reaction. The reaction liquid is sample by the apparatus for aspirating and discharging sample liquid, and is measured.
摘要翻译： 提供了一种小型，便宜且易于使用的自动化免疫化学垫层。 自动免疫化学分析仪包括至少一个在一个体内形成多个容器的一次性反应板，可以拉出用于安装反应板的工作台，可以拉出用于安装试样架的试验台，试剂恒温单元 ，反应温度单元，反应板保持部，抽吸和排出样品液体的装置，以及安装反应板保持部和用于吸取和排出样品液体的装置的XY移动部。 首先，通过XY移动部件，保持部件在使用前将反应板从用于安装反应板的工作台保持并移动到反应恒温器单元。 因此，通过XY移动部件，用于吸取和排出样品液体的装置在样品架，试剂恒温单元和反应恒温单元之间往复运动，从而将试样和试剂分配到反应板。 将分配的液体保持在恒温状态，摇动并搅拌，从而促进抗原 - 抗体反应。 反应液是用于吸取和排出样品液体的装置进行样品测量的。
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公开(公告)号：US5319954A
公开(公告)日：1994-06-14
申请号：US897851
申请日：1992-06-12
申请人： Noriaki Koeda , Takayoshi Izumi , Kunio Tanaka
发明人： Noriaki Koeda , Takayoshi Izumi , Kunio Tanaka
CPC分类号： G01N35/1016 , G01N2035/1018 , G01N2035/1025
摘要： In an automatic analyzer of samples, the liquid specimen and the reagent are mixed in a reaction container to react. If, however, there is a bubble in the reagent container, a accurate amount of a reagent may not be dispensed. Accordingly, a liquid surface detecting circuit for detecting the liquid surface on the basis of the impedance change between a pipet and a ground is disposed, and the height of the liquid surface before and after suction of the reagent is compared on the basis of the liquid surface detecting information, and the bubble is detected when the difference is more than a specified value, and accordingly the driving circuit of the driving source is controlled by the control circuit. Thus, when dispensing the reagent in the reagent container by a pipet, the bubble can be detected securely and accurately, and this apparatus may be used in a slender reagent container.
摘要翻译： 在样品的自动分析仪中，将液体样品和试剂混合在反应容器中进行反应。 然而，如果试剂容器中存在气泡，则可能不能分配精确量的试剂。 因此，设置用于基于移液管和地面之间的阻抗变化来检测液面的液面检测电路，并且基于液体比较试剂吸入前后的液面高度 表面检测信息，并且当该差大于指定值时检测气泡，并且因此驱动源的驱动电路由控制电路控制。 因此，当通过移液管将试剂分配到试剂容器中时，可以可靠且准确地检测气泡，并且该装置可以用于细长的试剂容器中。
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公开(公告)号：US07276376B2
公开(公告)日：2007-10-02
申请号：US10307922
申请日：2002-12-03
申请人： Masayuki Katayama , Susumu Hoshiko , Takayoshi Izumi , Yoshihiro Mishima , Wilfried Meyers , Norbert Zander
发明人： Masayuki Katayama , Susumu Hoshiko , Takayoshi Izumi , Yoshihiro Mishima , Wilfried Meyers , Norbert Zander
IPC分类号： G01N33/86
CPC分类号： G01N33/4905 , G01N21/82
摘要： An analyzing method of a blood coagulation reaction by detecting an optical change of a blood sample with an elapse of time, the method includes: setting at least one checkpoint or check region between a starting point of the blood coagulation reaction and the endpoint thereof; and monitoring a reaction state of the blood coagulation reaction at the checkpoint or in the check region to detect an abnormality of the blood coagulation reaction.
摘要翻译： 一种血液凝固反应的分析方法，通过检测血液样本的时间变化，该方法包括：设定血液凝固反应的起始点与其终点之间的至少一个检查点或检查区域; 并且在检查点或检查区域监测凝血反应的反应状态，以检测血液凝固反应的异常。
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8.发明授权公开(公告)号：US08788216B2
公开(公告)日：2014-07-22
申请号：US13194167
申请日：2011-07-29
CPC分类号： G01N33/493 , G01N15/04 , G01N33/48792 , G01N33/6827 , G01N33/70 , G01N33/80 , G01N35/00594 , G01N35/00871 , G01N35/1009 , G01N2015/0065 , G01N2015/0073 , G01N2035/00891 , G01N2333/76 , G01N2800/347 , G06F3/0482 , G06F19/26
摘要： A urine sample testing apparatus comprises: a urine qualitative measuring section configured to acquire a measurement result for each of a plurality of urine qualitative measurement items; a urine sediment measuring section configured to acquire a measurement result for each of a plurality of urine sediment measurement items; an operation part that is operable by a user to specify a combination of one of the plurality of urine qualitative measurement items and one of the plurality of urine sediment measurement items; an information processing unit configured to determine whether or not a first measurement result of the urine sample obtained by the urine qualitative measuring section and a second measurement result of the urine sample obtained by the urine sediment measuring section have a predetermined relationship with respect to the urine qualitative measurement item and the urine sediment measurement item included in the specified combination.
摘要翻译： 尿样检测装置包括：尿定性测定部，其构成为获取多个尿定性测定项目的测定结果; 尿沉渣测量部，被配置为获取多个尿沉渣测量项目中的每一个的测量结果; 操作部，其由用户操作，以指定所述多个尿定性测量项之一与所述多个尿沉渣测量项中的一个的组合; 信息处理单元，其被配置为确定由尿液定性测量部分获得的尿液样本的第一测量结果和由尿沉渣测量部分获得的尿液样本的第二测量结果是否具有关于尿液的预定关系 定性测量项目和包括在指定组合中的尿沉渣测量项目。
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9.发明申请URINE SAMPLE TESTING APPARATUS AND APPARATUS FOR PROCESSING MEASUREMENT RESULT OF URINE SAMPLE 有权尿液样品检测装置和尿液样品加工测定结果的装置公开(公告)号：US20120035879A1
公开(公告)日：2012-02-09
申请号：US13194167
申请日：2011-07-29
CPC分类号： G01N33/493 , G01N15/04 , G01N33/48792 , G01N33/6827 , G01N33/70 , G01N33/80 , G01N35/00594 , G01N35/00871 , G01N35/1009 , G01N2015/0065 , G01N2015/0073 , G01N2035/00891 , G01N2333/76 , G01N2800/347 , G06F3/0482 , G06F19/26
摘要： A urine sample testing apparatus comprises: a urine qualitative measuring section configured to acquire a measurement result for each of a plurality of urine qualitative measurement items; a urine sediment measuring section configured to acquire a measurement result for each of a plurality of urine sediment measurement items; an operation part that is operable by a user to specify a combination of one of the plurality of urine qualitative measurement items and one of the plurality of urine sediment measurement items; an information processing unit configured to determine whether or not a first measurement result of the urine sample obtained by the urine qualitative measuring section and a second measurement result of the urine sample obtained by the urine sediment measuring section have a predetermined relationship with respect to the urine qualitative measurement item and the urine sediment measurement item included in the specified combination.
摘要翻译： 尿样检测装置包括：尿定性测定部，其构成为获取多个尿定性测定项目的测定结果; 尿沉渣测量部，被配置为获取多个尿沉渣测量项目中的每一个的测量结果; 操作部，其由用户操作，以指定所述多个尿定性测量项之一与所述多个尿沉渣测量项中的一个的组合; 信息处理单元，其被配置为确定由尿液定性测量部分获得的尿液样本的第一测量结果和由尿沉渣测量部分获得的尿液样本的第二测量结果是否具有关于尿液的预定关系 定性测量项目和包括在指定组合中的尿沉渣测量项目。
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公开(公告)号：US5215714A
公开(公告)日：1993-06-01
申请号：US709062
申请日：1991-05-30
IPC分类号： G01N35/10
CPC分类号： G01N35/1009 , G01N2035/1025 , G01N2035/1086 , G01N35/1004
摘要： A buffer solution is sampled from a buffer solution vessel and is dispensed into a reaction vessel on a reaction table by first sampling/dispensing means, and a specimen containing an antigen or antibody to be measured is sampled from a specimen vessel and is dispensed into the reaction vessel by second sampling/dispensing means. A reagent containing insoluble carriers to which is bonded an antibody or antigen that specifically reacts with the antigen or antibody in the specimen is sampled from a reagent vessel and dispensed into the reaction vessel by third sampling/dispensing means. The entire reaction table is shaken continuously during mixing of the buffer solution, reagent and specimen, and the reaction vessel is maintained in an isothermal state. A stable antigen-antibody reaction in the resulting reaction solution is thus promoted to form an agglutinate of the insoluble carriers. The reaction solution is sampled from the reaction vessel and dispensed into a sample chamber by fourth sampling/dispensing means. The dispensed reaction solution is transferred to a detector through which the insoluble carriers are passed and in which a signal is generated based upon a difference in terms of electrical or optical characteristics. The degree of agglutination of the insoluble carriers is obtained as a numerical value, thus making it possible to quantify the antigen or antibody of interest contained in the specimen.
摘要翻译： 缓冲溶液从缓冲溶液容器中取样，并通过第一取样/分配装置分配到反应台上的反应容器中，并从样品容器中取出含有待测量的抗原或抗体的样品，并将其分配到 反应容器通过第二采样/分配装置。 从试剂容器中取出含有与试样中的抗原或抗体特异性反应的抗体或抗原结合的不溶性载体的试剂，并通过第三取样/分注装置分配到反应容器中。 在缓冲溶液，试剂和试样的混合过程中，整个反应台连续摇动，反应容器保持在等温状态。 因此促进所得反应溶液中的稳定的抗原 - 抗体反应形成不溶性载体的凝集物。 反应溶液从反应容器中取样并通过第四取样/分配装置分配到样品室中。 分配的反应溶液转移到不可溶载体通过的检测器，并且基于电或光学特性的差异产生信号。 获得不溶性载体的凝集度作为数值，从而可以定量试样中包含的感兴趣的抗原或抗体。
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