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    METHOD FOR PRODUCING OPTICALLY ACTIVE a-IONONE
    1.
    发明申请
    METHOD FOR PRODUCING OPTICALLY ACTIVE a-IONONE 有权
    用于生产光学活性α-离子的方法

    公开(公告)号：US20110118500A1

    公开(公告)日：2011-05-19

    申请号：US13012199

    申请日：2011-01-24

    申请人： Tetsuya Yamamoto ,  Kenji Yagi ,  Kenya Ishida

    发明人： Tetsuya Yamamoto ,  Kenji Yagi ,  Kenya Ishida

    IPC分类号： C07C69/78 ,  C07C69/533 ,  C07C69/63 ,  C07C69/24 ,  C07C69/708

    CPC分类号： C12P7/26 ,  A23L2/56 ,  A23L27/204 ,  A61K8/37 ,  A61Q11/00 ,  A61Q13/00 ,  C07B53/00 ,  C07B2200/07 ,  C07C403/08 ,  C07C403/12 ,  C07C403/14 ,  C07C2601/16 ,  C12G3/06 ,  C12P41/004

    摘要： Provided that a method for inexpensively producing optically active α-ionone with a high yield and a high asymmetric yield and with good workability in a short process, and a perfume composition comprising the optically active α-ionone obtained by the aforementioned method. A method for producing optically active α-ionone, comprising allowing α-ionone as a mixture of optical isomers to react with an esterification agent, and hydrolyzing the obtained α-ionone enol ester; a method for producing optically active α-ionone comprising subjecting α-ionone as a mixture of optical isomers to an asymmetric reduction, allowing the obtained optically active α-ionol to react with an esterification agent to give an optically active α-ionol ester, hydrolyzing the obtained optically active α-ionol ester after purification as necessary, and then oxidizing the obtained optically active α-ionol; and a perfume composition comprising thus obtained optically active α-ionone.

    摘要翻译： 本发明提供了一种低成本地生产光学活性α-紫罗兰酮的方法，其具有高产率和高不对称产率，并且在短时间内具有良好的可加工性，以及包含通过上述方法获得的光学活性α-紫罗兰酮的香料组合物。 一种光学活性α-紫罗兰酮的制造方法，其特征在于，使作为旋光异构体的混合物的α-紫罗烯酮与酯化反应，水解得到的α-紫罗烯酮烯醇酯; 一种光学活性α-紫罗兰酮的制造方法，其特征在于，将α-紫罗烯酮作为光学异构体的混合物进行不对称还原，使得所得光学活性α-离子酚与酯化反应，得到光学活性α-离子醇酯，水解 根据需要纯化后得到的光学活性α-离子醇酯，然后氧化所得光学活性α-离子醇; 和包含这样得到的光学活性α-紫罗兰酮的香料组合物。

    Method for producing optically active α-ionone
    2.
    发明授权
    Method for producing optically active α-ionone 有权

    公开(公告)号：US07902404B2

    公开(公告)日：2011-03-08

    申请号：US11991966

    申请日：2006-09-13

    申请人： Tetsuya Yamamoto ,  Kenji Yagi ,  Kenya Ishida

    发明人： Tetsuya Yamamoto ,  Kenji Yagi ,  Kenya Ishida

    IPC分类号： C07C45/42

    CPC分类号： C12P7/26 ,  A23L2/56 ,  A23L27/204 ,  A61K8/37 ,  A61Q11/00 ,  A61Q13/00 ,  C07B53/00 ,  C07B2200/07 ,  C07C403/08 ,  C07C403/12 ,  C07C403/14 ,  C07C2601/16 ,  C12G3/06 ,  C12P41/004

    摘要： Provided that a method for inexpensively producing optically active α-ionone with a high yield and a high asymmetric yield and with good workability in a short process, and a perfume composition comprising the optically active α-ionone obtained by the aforementioned method. A method for producing optically active α-ionone, comprising allowing α-ionone as a mixture of optical isomers to react with an esterification agent, and hydrolyzing the obtained α-ionone enol ester; a method for producing optically active α-ionone comprising subjecting α-ionone as a mixture of optical isomers to an asymmetric reduction, allowing the obtained optically active α-ionol to react with an esterification agent to give an optically active α-ionol ester, hydrolyzing the obtained optically active α-ionol ester after purification as necessary, and then oxidizing the obtained optically active α-ionol; and a perfume composition comprising thus obtained optically active α-ionone.

    Method for producing optically active α-ionone
    3.
    发明授权
    Method for producing optically active α-ionone 有权
    光学活性α-紫罗兰酮的制造方法

    公开(公告)号：US08053592B2

    公开(公告)日：2011-11-08

    申请号：US13012199

    申请日：2011-01-24

    申请人： Tetsuya Yamamoto ,  Kenji Yagi ,  Kenya Ishida

    发明人： Tetsuya Yamamoto ,  Kenji Yagi ,  Kenya Ishida

    IPC分类号： C07C69/78 ,  C07C69/533 ,  C07C69/63

    CPC分类号： C12P7/26 ,  A23L2/56 ,  A23L27/204 ,  A61K8/37 ,  A61Q11/00 ,  A61Q13/00 ,  C07B53/00 ,  C07B2200/07 ,  C07C403/08 ,  C07C403/12 ,  C07C403/14 ,  C07C2601/16 ,  C12G3/06 ,  C12P41/004

    摘要： Provided that a method for inexpensively producing optically active α-ionone with a high yield and a high asymmetric yield and with good workability in a short process, and a perfume composition comprising the optically active α-ionone obtained by the aforementioned method. A method for producing optically active α-ionone, comprising allowing α-ionone as a mixture of optical isomers to react with an esterification agent, and hydrolyzing the obtained α-ionone enol ester; a method for producing optically active α-ionone comprising subjecting α-ionone as a mixture of optical isomers to an asymmetric reduction, allowing the obtained optically active α-ionol to react with an esterification agent to give an optically active α-ionol ester, hydrolyzing the obtained optically active α-ionol ester after purification as necessary, and then oxidizing the obtained optically active α-ionol; and a perfume composition comprising thus obtained optically active α-ionone.

    摘要翻译： 本发明提供了一种低成本地生产光学活性α-紫罗兰酮的方法，其具有高产率和高不对称产率，并且在短时间内具有良好的可加工性，以及包含通过上述方法获得的光学活性α-紫罗兰酮的香料组合物。 一种光学活性α-紫罗兰酮的制造方法，其特征在于，使作为旋光异构体的混合物的α-紫罗烯酮与酯化反应，水解得到的α-紫罗烯酮烯醇酯; 一种光学活性α-紫罗兰酮的制造方法，其特征在于，将α-紫罗烯酮作为光学异构体的混合物进行不对称还原，使得所得光学活性α-离子酚与酯化反应，得到光学活性α-离子醇酯，水解 根据需要纯化后得到的光学活性α-离子醇酯，然后氧化所得光学活性α-离子醇; 和包含这样得到的光学活性α-紫罗兰酮的香料组合物。

    Method for Producing Optically Active Alpha-Ionone
    4.
    发明申请
    Method for Producing Optically Active Alpha-Ionone 有权
    生产光学活性α-紫罗兰酮的方法

    公开(公告)号：US20090216039A1

    公开(公告)日：2009-08-27

    申请号：US11991966

    申请日：2006-09-13

    申请人： Tetsuya Yamamoto ,  Kenji Yagi ,  Kenya Ishida

    发明人： Tetsuya Yamamoto ,  Kenji Yagi ,  Kenya Ishida

    IPC分类号： C12P7/26 ,  C07C69/75 ,  C07C45/42

    CPC分类号： C12P7/26 ,  A23L2/56 ,  A23L27/204 ,  A61K8/37 ,  A61Q11/00 ,  A61Q13/00 ,  C07B53/00 ,  C07B2200/07 ,  C07C403/08 ,  C07C403/12 ,  C07C403/14 ,  C07C2601/16 ,  C12G3/06 ,  C12P41/004

    摘要： Provided that a method for inexpensively producing optically active α-ionone with a high yield and a high asymmetric yield and with good workability in a short process, and a perfume composition comprising the optically active α-ionone obtained by the aforementioned method. A method for producing optically active α-ionone, comprising allowing α-ionone as a mixture of optical isomers to react with an esterification agent, and hydrolyzing the obtained α-ionone enol ester; a method for producing optically active α-ionone comprising subjecting α-ionone as a mixture of optical isomers to an asymmetric reduction, allowing the obtained optically active α-ionol to react with an esterification agent to give an optically active α-ionol ester, hydrolyzing the obtained optically active α-ionol ester after purification as necessary, and then oxidizing the obtained optically active α-ionol; and a perfume composition comprising thus obtained optically active α-ionone.

    摘要翻译： 本发明提供了一种低成本地生产光学活性α-紫罗兰酮的方法，其具有高产率和高不对称产率，并且在短时间内具有良好的可加工性，以及包含通过上述方法获得的光学活性α-紫罗兰酮的香料组合物。 一种光学活性α-紫罗兰酮的制造方法，其特征在于，使作为光学异构体的混合物的α-紫罗兰酮与酯化剂反应，水解得到的α-紫罗兰酮烯醇酯; 制备光学活性α-紫罗兰酮的方法，包括将α-紫罗烯酮作为光学异构体的混合物进行不对称还原，使得到的光学活性α-离子酚与酯化反应得到光学活性α-离子醇酯，水解 根据需要纯化后得到的光学活性α-离子醇酯，然后氧化得到的光学活性α-离子醇; 和包含由此获得的光学活性α-紫罗兰酮的香料组合物。

    HUMECTANT COMPOSITION
    5.
    发明申请
    HUMECTANT COMPOSITION 审中-公开
    成分组成

    公开(公告)号：US20080171794A1

    公开(公告)日：2008-07-17

    申请号：US12014925

    申请日：2008-01-16

    申请人： Tetsuya Yamamoto ,  Kenya Ishida

    发明人： Tetsuya Yamamoto ,  Kenya Ishida

    IPC分类号： A61K31/075 ,  A61K8/33

    CPC分类号： A61K8/345 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q13/00 ,  A61Q19/00 ,  A61Q19/10

    摘要： The present invention relates to a humectant composition containing, as component (A), at least one member selected from a menthol derivative represented by the following formula (1) and p-menthane-3,8-diol: in which R is an alkylene group having 2 to 5 carbon atoms which may be substituted with at least one member selected from the group consisting of a methyl group and a hydroxyl group, and n is an integer of 1 to 3. The humectant composition of the present invention provides an excellent moisture-retention effect.

    摘要翻译： 本发明涉及作为组分（A）的至少一种选自由下式（1）表示的薄荷醇衍生物和对 - 薄荷烷-3,8-二醇中的至少一种的组合物：其中R是亚烷基 具有2至5个碳原子的基团，其可以被选自甲基和羟基中的至少一种取代，n是1至3的整数。本发明的保湿组合物提供优异的 保湿效果。

    LIPID COMPOSITION HAVING EXCELLENT SHAPE RETENTION PROPERTY AND PRODUCT
    8.
    发明申请
    LIPID COMPOSITION HAVING EXCELLENT SHAPE RETENTION PROPERTY AND PRODUCT 有权
    具有优异形状保持性能和产品的脂肪组合物

    公开(公告)号：US20100093682A1

    公开(公告)日：2010-04-15

    申请号：US12529272

    申请日：2008-02-27

    申请人： Kenya Ishida ,  Chiyomi Birou ,  Tetsuya Yamamoto

    发明人： Kenya Ishida ,  Chiyomi Birou ,  Tetsuya Yamamoto

    IPC分类号： A61K31/568 ,  A61Q19/00 ,  A24B15/10 ,  A61K8/18 ,  C11D3/20 ,  C09K3/00

    CPC分类号： A61K47/28 ,  A23L27/203 ,  A23L33/11 ,  A23V2002/00 ,  A24B15/30 ,  A61K8/34 ,  A61K8/63 ,  A61Q19/00 ,  A23V2200/208 ,  A23V2250/21 ,  A23V2250/18

    摘要： It is to provide a technique for preventing aggregation or caking of menthol at the time of its keeping. In addition, it is to provide a lipid composition, which can show excellent thermal stability even in the case of high temperature at the time of keeping menthol and at the time of blending in a product, does not cause mutual aggregation of powders, particles, flakes, pellets, sticks and the like of menthol, and can maintain its shape retention property. From 10 to 50% by mass of sterols are added to and mixed with from 50 to 90% by mass of menthol, and the resultant is melted with heating. Paraffins may be further added and mixed in an amount of 20% by mass or less, based on the lipid composition.

    摘要翻译： 它是提供一种防止薄荷醇保留时聚集或结块的技术。 此外，提供一种脂质组合物，即使在保持薄荷醇时的高温的情况下也能显示优异的热稳定性，并且在产品中混合时，不会引起粉末，颗粒， 片，丸，棒等，并能保持其形状保持性。 加入10〜50质量％的甾醇并与50〜90质量％的薄荷醇混合，加热熔融。 基于脂质组成，石蜡可以进一步添加并混合20质量％以下。

    COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION
    9.
    发明申请
    COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION 失效
    冷却感觉剂组合物和感觉刺激剂组合物

    公开(公告)号：US20110117147A1

    公开(公告)日：2011-05-19

    申请号：US12936160

    申请日：2009-04-01

    申请人： Kenya Ishida ,  Takashi Aida ,  Tetsuya Yamamoto

    发明人： Kenya Ishida ,  Takashi Aida ,  Tetsuya Yamamoto

    IPC分类号： A61K8/49 ,  A61K8/55 ,  A61Q11/00 ,  C07C69/96 ,  C07D317/22 ,  A61Q17/00 ,  A61K31/357

    CPC分类号： C07D317/36 ,  A23L27/203 ,  A23L27/2052 ,  A61K8/0208 ,  A61K8/37 ,  A61K8/4973 ,  A61K2800/244 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q19/00 ,  A61Q19/10 ,  C07C69/24 ,  C07C69/96 ,  C07C2601/14

    摘要： The invention relates to a cooling sensation agent composition with a prolonged cool sensation effect comprising at least one compound selected from Formula (1) wherein each of A and B is a hydrogen atom or a hydrocarbon group which may have one or more substituents, in which A and B are not hydrogen atoms simultaneously, and the total number of carbon atoms in A and B is in the range of 6 to 18; and Formulae (2) to (4) wherein R1, R2, and R3 each represent a residue of an alcohol selected from 1-menthol, 1-isopulegol, 3-(1-menthoxy)propan-1,2-diol, 2-(1-menthoxy)ethan-1-ol, 3-(1-menthoxy)propan-1-ol, 2-methyl-3-(1-menthoxy)propan-1,2-diol and para-menthan-3,8-diol), and R4 represents a residue of a branched or straight-chain, cyclic or linear, or saturated or unsaturated alcohol having 6 to 18 carbon atoms that may have one or more aromatic rings that may have a condensed ring and substituent groups such as hydroxyl and ether groups; and R6 represents a hydrocarbon group having 11 to 19 carbon atoms that may be branched and contain one or more unsaturated bonds. The invention also relates to a sensory stimulation agent composition comprising the cooling sensation agent composition; a flavor or fragrance composition, a beverage or food product, a perfume or cosmetic product, a toiletry product, a daily utensil product or grocery, a fiber, a fiber product, a cloth or a medicine comprising the cooling sensation agent composition or the sensory stimulation agent composition; a production method thereof; a cooling processing method of a fiber, fiber product or a cloth, comprising compounding the cooling sensation agent composition or the sensory stimulation agent composition; and new compounds.

    摘要翻译： 本发明涉及具有延长的凉爽感觉效果的冷却感觉剂组合物，其包含至少一种选自式（1）的化合物，其中A和B各自为氢原子或可具有一个或多个取代基的烃基，其中 A和B不同时为氢原子，A和B中碳原子总数为6〜18; 和式（2）至（4）其中R 1，R 2和R 3各自表示选自1-薄荷醇，1-异胡耳醇，3-（1-薄荷氧基）丙-1,2-二醇，2- （1-薄荷氧基）乙-1-醇，3-（1-薄荷氧基）丙-1-醇，2-甲基-3-（1-薄荷氧基）丙-1,2-二醇和对 - 薄荷烷-3,8 - 二醇），R4代表具有6-18个碳原子的支链或直链，环状或直链或饱和或不饱和醇的残基，其可具有一个或多个可具有稠环的芳环和取代基如 作为羟基和醚基团; R6表示可以具有支链并含有一个以上的不饱和键的碳原子数为11〜19的烃基。 本发明还涉及包含冷却感觉剂组合物的感觉刺激剂组合物; 香料或香料组合物，饮料或食品，香水或化妆品，化妆品，日常用品或杂货，纤维，纤维制品，布或包含该冷却感觉组合物或感官的药物 刺激剂组成; 其制造方法; 纤维，纤维制品或布的冷却处理方法，其包括将冷却感觉剂组合物或感觉刺激剂组合物混合; 和新化合物。

    HUMECTANT COMPOSITION
    10.
    发明申请
    HUMECTANT COMPOSITION 审中-公开
    成分组成

    公开(公告)号：US20110077309A1

    公开(公告)日：2011-03-31

    申请号：US12959670

    申请日：2010-12-03

    申请人： Tetsuya Yamamoto ,  Kenya Ishida

    发明人： Tetsuya Yamamoto ,  Kenya Ishida

    IPC分类号： A61K47/42 ,  A61K47/10 ,  A61K47/14 ,  A61K47/22 ,  A61K47/36 ,  A61K47/46 ,  A61Q5/12 ,  A61Q19/00 ,  A61P17/00 ,  A61K8/33 ,  A61Q13/00

    CPC分类号： A61K8/345 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q13/00 ,  A61Q19/00 ,  A61Q19/10

    摘要： The present invention relates to a humectant composition containing, as component (A), at least one member selected from a menthol derivative represented by the following formula (1) and p-menthane-3,8-diol: in which R is an alkylene group having 2 to 5 carbon atoms which may be substituted with at least one member selected from the group consisting of a methyl group and a hydroxyl group, and n is an integer of 1 to 3. The humectant composition of the present invention provides an excellent moisture-retention effect.

    摘要翻译： 本发明涉及作为组分（A）的至少一种选自由下式（1）表示的薄荷醇衍生物和对 - 薄荷烷-3,8-二醇中的至少一种的组合物：其中R是亚烷基 具有2至5个碳原子的基团，其可以被选自甲基和羟基中的至少一种取代，n是1至3的整数。本发明的保湿组合物提供优异的 保湿效果。