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    Laser microdissection apparatus and method
    2.
    发明申请
    Laser microdissection apparatus and method 有权
    激光显微解剖设备及方法

    公开(公告)号：US20060087643A1

    公开(公告)日：2006-04-27

    申请号：US11222281

    申请日：2005-09-08

    申请人： Brian Donovan ,  Thomas Baer

    发明人： Brian Donovan ,  Thomas Baer

    IPC分类号： G01N1/00

    CPC分类号： G01N1/28 ,  G01N1/2813 ,  G01N1/286 ,  G01N1/30 ,  G01N1/44 ,  G01N2001/2826 ,  G01N2001/2833 ,  G01N2001/284 ,  G01N2001/2886 ,  Y10T156/10 ,  Y10T156/1054

    摘要： Systems and methods for automated laser microdissection are disclosed. In one variation, targeted biological material is manually or automatically selected and a transfer film is placed in juxtaposition to the location of an interior of a cut path. In another variation, a sample of biological material is mounted onto a polymer membrane which is then placed onto a substrate. Targeted biological material is manually or automatically selected and a transfer film is placed in juxtaposition with the targeted biological material on the side of the biological material. In yet another variation, a sample of biological material is mounted onto a polymer membrane which is then inverted onto a substrate. Targeted biological material is manually or automatically selected and a transfer film is placed in juxtaposition with the targeted biological material on the side of the polymer membrane. Then, an UV laser cuts along a cut path around the targeted portions of biological material in a closed cut path or a substantially closed cut path defining an interior and an exterior portion of the tissue sample. In a substantially closed cut path, bridges are left spanning the interior of the cut path and the exterior of the cut path. An IR laser activates at least a portion of the transfer film such that the transfer film in the vicinity of targeted portion adheres to the biological material interior to the cut path. The transfer film is then removed separating the targeted portions of biological material which are adhered to the transfer film from the remaining portion of the tissue sample.

    摘要翻译： 公开了用于自动激光显微切割的系统和方法。 在一个变型中，手动或自动选择目标生物材料，并且将转移膜并排放置在切割路径的内部的位置。 在另一个变体中，将生物材料样品安装在聚合物膜上，然后将其放置在基底上。 手动或自动选择靶向生物材料，并将转移膜与生物材料侧面上的靶向生物材料并置放置。 在另一个变体中，将生物材料样品安装在聚合物膜上，然后将其反转到基底上。 手动或自动选择目标生物材料，并将转移膜与聚合物膜侧面上的目标生物材料并置放置。 然后，UV激光沿着围绕生物材料的目标部分的切割路径沿封闭的切割路径或限定组织样本的内部和外部部分的基本封闭的切割路径切割。 在基本封闭的切割路径中，跨越切割路径的内部和切割路径的外部。 红外激光激活转印膜的至少一部分，使得目标部分附近的转印膜附着在生物材料内部至切割路径。 然后除去转移膜，从生物材料的目标部分分离出粘附到转移膜上的剩余部分的组织样品。

    Cement delivering device and method
    3.
    发明授权
    Cement delivering device and method 有权
    水泥输送装置及方法

    公开(公告)号：US09095394B2

    公开(公告)日：2015-08-04

    申请号：US13456597

    申请日：2012-04-26

    申请人： Bryan Click ,  Brian Donovan

    发明人： Bryan Click ,  Brian Donovan

    IPC分类号： A61B17/58 ,  A61B17/88 ,  A61M5/315 ,  A61M5/20

    CPC分类号： A61B17/8802 ,  A61B17/8805 ,  A61B17/8822 ,  A61B17/8827 ,  A61M5/2053 ,  A61M5/315 ,  A61M5/31515 ,  A61M2202/0007

    摘要： A delivery system includes a reservoir for storing pressurized fluid and a piston rod passing through the reservoir and having an end portion with a dimension larger than the piston rod. A sleeve is configured to engage the end portion of the piston rod such that when the piston rod is advanced, the end portion seals an opening in the sleeve. The sleeve and the end portion function as a piston for extracting fluid from a delivery chamber. When the piston rod is retracted, the sleeve engages a portion of the end portion to permit the reservoir to communicate with the delivery chamber through the opening. Methods of use are disclosed.

    摘要翻译： 输送系统包括用于存储加压流体的储存器和通过储存器的活塞杆，并具有尺寸大于活塞杆的端部。 套筒构造成与活塞杆的端部接合，使得当活塞杆前进时，端部密封套筒中的开口。 套筒和端部部分用作用于从输送室提取流体的活塞。 当活塞杆缩回时，套筒接合端部的一部分，以允许储存器通过开口与输送室连通。 公开了使用方法。

    CEMENT DELIVERING DEVICE AND METHOD
    4.
    发明申请
    CEMENT DELIVERING DEVICE AND METHOD 有权

    公开(公告)号：US20130289571A1

    公开(公告)日：2013-10-31

    申请号：US13456597

    申请日：2012-04-26

    申请人： Bryan Click ,  Brian Donovan

    发明人： Bryan Click ,  Brian Donovan

    IPC分类号： A61B17/58

    CPC分类号： A61B17/8802 ,  A61B17/8805 ,  A61B17/8822 ,  A61B17/8827 ,  A61M5/2053 ,  A61M5/315 ,  A61M5/31515 ,  A61M2202/0007

    摘要： A delivery system includes a reservoir for storing pressurized fluid and a piston rod passing through the reservoir and having an end portion with a dimension larger than the piston rod. A sleeve is configured to engage the end portion of the piston rod such that when the piston rod is advanced, the end portion seals an opening in the sleeve. The sleeve and the end portion function as a piston for extracting fluid from a delivery chamber. When the piston rod is retracted, the sleeve engages a portion of the end portion to permit the reservoir to communicate with the delivery chamber through the opening. Methods of use are disclosed.

    Zero overhead computer interrupts with task switching
    8.
    发明授权
    Zero overhead computer interrupts with task switching 失效
    零开销计算机中断与任务切换

    公开(公告)号：US06981133B1

    公开(公告)日：2005-12-27

    申请号：US09410202

    申请日：1999-09-30

    申请人： Brian Donovan

    发明人： Brian Donovan

    IPC分类号： G06F9/46 ,  G06F9/48 ,  G06F9/40

    CPC分类号： G06F9/462

    摘要： The invention constitutes a unique hardware zero overhead interrupt and task change mechanism for the reduction or elimination of interrupt latency and task change processing overhead delays in computer architectures. Without loss of time, the system performs complete task state saving and restoration between one cycle and the next without software intervention. For each Central Processing Unit (1) register, the invention uses one or more auxiliary latches (3, 4) wherein one latch (3, 4) is used as the “running” latch and one of the auxiliary latches is attached to task storage memory. The invention swaps connections between alternate “running” registers and auxiliary registers while transferring other tasks to and from task storage memory (2). The invention provides a task linking system to allow the linking of tasks for the mandatory sequential execution of the linked tasks. Further, the invention includes a priority “impatience” counter system to increase the relative priorities of various tasks as they approach their task deadlines.

    摘要翻译： 本发明构成了用于减少或消除计算机体系结构中的中断延迟和任务改变处理开销延迟的独特的硬件零开销中断和任务改变机制。 在不损失时间的情况下，系统在一个周期和下一个周期之间完成任务状态保存和恢复，而无需软件干预。 对于每个中央处理单元（1）寄存器，本发明使用一个或多个辅助锁存器（3,4），其中一个锁存器（3,4）用作“运行”锁存器，并且一个辅助锁存器附接到任务存储器 记忆。 本发明在将另外的任务传送到任务存储存储器（2）和/或从任务存储存储器（2）传送其他任务的同时，交替地替换“运行”寄存器和辅 本发明提供了一种任务链接系统以允许链接任务以强制连续执行链接的任务。 此外，本发明包括优先“不耐烦”的计数器系统，以在各种任务接近其任务期限时增加各种任务的相对优先级。

    Precision timing pulse width communications transforming reshaped pulse stream
    9.
    发明授权
    Precision timing pulse width communications transforming reshaped pulse stream 有权
    精密定时脉冲宽度通信转换重构脉冲流

    公开(公告)号：US08229006B2

    公开(公告)日：2012-07-24

    申请号：US12380381

    申请日：2009-02-25

    申请人： William B. Dress ,  Brian Donovan

    发明人： William B. Dress ,  Brian Donovan

    IPC分类号： H04B14/04

    CPC分类号： H04B14/04 ,  H04L25/4902 ,  H04L27/34

    摘要： Pulse communications using precision timing includes detecting a pulse stream from a pulse code modulated carrier signal; transforming the pulse stream into a reshaped pulse stream; transforming the reshaped pulse stream into a counter gate stream; and recovering a data stream from the counter gate stream. The reshaped pulse stream is transformed into the counter gate stream with a digital circuit.

    摘要翻译： 使用精确定时的脉冲通信包括从脉冲编码调制载波信号检测脉冲流; 将脉冲流转换成重新形成的脉冲流; 将重新形成的脉冲流转换成计数器流; 以及从计数器门流中恢复数据流。 重新形成的脉冲流通过数字电路转换成计数器门流。