利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

18 条记录 (耗时 0.023 秒)

    PERMANENT HYDROPHILIC NONWOVEN
    2.
    发明申请
    PERMANENT HYDROPHILIC NONWOVEN 审中-公开
    永久性非亲水性

    公开(公告)号：US20110124255A1

    公开(公告)日：2011-05-26

    申请号：US12952733

    申请日：2010-11-23

    申请人： Thomas Broch-Nielsen ,  Jens Bøndergaard ,  Flemming Besenbacher ,  Peter Kingshott

    发明人： Thomas Broch-Nielsen ,  Jens Bøndergaard ,  Flemming Besenbacher ,  Peter Kingshott

    IPC分类号： B32B27/08 ,  B05D3/04 ,  B32B27/12

    CPC分类号： D06M10/025 ,  A61F13/511 ,  D06M15/00 ,  D06M15/285 ,  D06M23/005 ,  Y10T442/2041 ,  Y10T442/2484

    摘要： The present invention relates to a process for coating a polymer nonwoven comprising the steps of: plasma and/or corona assisted treatment of the surface of the nonwoven to obtain a charged and/or polar surface; and formation of a first coating layer comprising at least one first charged and/or polar species, the first species being a hydrophilic polymer, wherein the overall charge or partial charge facing the nonwoven surface of the first species carries the opposite sign from the average charge introduced to the nonwoven fiber surface in step a).

    摘要翻译： 本发明涉及一种涂覆聚合物非织造布的方法，包括以下步骤：等离子体和/或电晕辅助处理非织造材料的表面以获得带电和/或极性表面; 以及形成包含至少一种第一带电和/或极性物质的第一涂层，第一种是亲水性聚合物，其中面向第一物质的非织造表面的总电荷或部分电荷与平均电荷相反， 在步骤a）中引入非织造纤维表面。

    THREE-DIMENSIONAL NANOSTRUCTURED HYBRID SCAFFOLD AND MANUFACTURE THEREOF
    5.
    发明申请
    THREE-DIMENSIONAL NANOSTRUCTURED HYBRID SCAFFOLD AND MANUFACTURE THEREOF 有权
    三维纳米结构杂交及其制造

    公开(公告)号：US20120128739A1

    公开(公告)日：2012-05-24

    申请号：US13377430

    申请日：2010-06-25

    申请人： Jens Vinge Nygaard ,  Lea Bjerre ,  Cody Eric Bunger ,  Flemming Besenbacher

    发明人： Jens Vinge Nygaard ,  Lea Bjerre ,  Cody Eric Bunger ,  Flemming Besenbacher

    IPC分类号： A61K9/00 ,  A61K35/12 ,  C12N5/071

    CPC分类号： C12N5/0602 ,  A61L27/34 ,  A61L27/56 ,  C12N2533/20 ,  C12N2533/50

    摘要： A method of making a three-dimensional biocompatible scaffold capable of supporting cell activities such as growth and differentiation, the method includes providing a supporting grid that forms an open network and provides mechanical support of a second biocompatible material. The second biocompatible material has interconnected cavities that allow nutrients, metabolites and soluble factors to diffuse throughout the scaffold. The scaffold design can be understood as a hierarchically organised structure. At the micron to submicron length scale a top/down manufacturing approach is used to make a structure that will constitute the frame into which a bottom/up processing approach is applied to form an open porous scaffold with specific nano sized features. The advantage of this hierarchically organised design is that benefits can be drawn independently from both the micron and the nano sized structures, promoting specific cell activities and providing sufficient mechanical compliance.

    摘要翻译： 制备能够支持细胞活性如生长和分化的三维生物相容性支架的方法包括提供形成开放网络并提供第二生物相容性材料的机械支撑的支撑网格。 第二种生物相容性材料具有互连的空腔，其允许营养物，代谢物和可溶性因子在整个支架中扩散。 脚手架设计可以理解为层次结构。 在微米到亚微米长度尺度上，使用顶部/底部制造方法来制造构成框架的结构，其中应用底部/上部加工方法以形成具有特定纳米尺寸特征的开放多孔支架。 这种分级组织设计的优点在于可以独立于微米和纳米尺寸的结构，从而促进特定的细胞活动并提供足够的机械依从性。

    METHOD FOR CALCULATING PRESSURES IN A FLUID STREAM THROUGH A TUBE SECTION, ESPECIALLY A BLOOD VESSEL WITH ATHEROSCLEROTIC PLAQUE
    6.
    发明申请
    METHOD FOR CALCULATING PRESSURES IN A FLUID STREAM THROUGH A TUBE SECTION, ESPECIALLY A BLOOD VESSEL WITH ATHEROSCLEROTIC PLAQUE 审中-公开
    通过管段计算流体流中的压力的​​方法，特别是具有自由流动性的血管

    公开(公告)号：US20100298719A1

    公开(公告)日：2010-11-25

    申请号：US12734429

    申请日：2008-10-31

    申请人： Samuel Alberg Kock ,  Jens Vinge Nygaard ,  Flemming Besenbacher ,  Won Yong Kim

    发明人： Samuel Alberg Kock ,  Jens Vinge Nygaard ,  Flemming Besenbacher ,  Won Yong Kim

    IPC分类号： A61B5/021

    CPC分类号： A61B5/02028 ,  A61B5/055 ,  G06T7/0012 ,  G06T2207/10072 ,  G06T2207/20044 ,  G06T2207/30104 ,  G16H50/50

    摘要： A method for calculating pressures in a fluid streaming through a tube section from an upstream end to a downstream end of the tube section, the method comprising scanning the tube section with a scanner and providing a plurality of 2D scanning images along the tube section with an inlet and at least two arms, by a computer program on the basis of the 2D images automatically N calculating a 3D image of the tube section by using interpolating between the 2D images, by a computer program performing a 2D sectional image cut through the 3D image, the image cut following the fluid stream, calculating in the sectional image cut a fluid pressure distribution along multiple locations inside the tube on the basis of given boundary conditions, the boundary conditions including fluid velocity or fluid pressure at the upstream end.

    摘要翻译： 一种用于计算从管部分从管部分的上游端到下游端流动的流体中的压力的​​方法，所述方法包括用扫描仪扫描管部分，并且沿着管部分提供多个2D扫描图像， 入口和至少两个臂，通过基于2D图像的计算机程序自动地通过在2D图像之间进行内插来计算管部分的3D图像，通过执行通过3D图像切割的2D截面图像的计算机程序 根据流体流切割的图像，根据给定的边界条件，边界条件包括流体速度或上游端的流体压力，在截面图像中计算切割管内多个位置的流体压力分布。

    Three-dimensional nanostructured hybrid scaffold and manufacture thereof
    9.
    发明授权
    Three-dimensional nanostructured hybrid scaffold and manufacture thereof 有权
    三维纳米结构杂交支架及其制造

    公开(公告)号：US08815276B2

    公开(公告)日：2014-08-26

    申请号：US13377430

    申请日：2010-06-25

    申请人： Jens Vinge Nygaard ,  Lea Bjerre ,  Cody Eric Bünger ,  Flemming Besenbacher

    发明人： Jens Vinge Nygaard ,  Lea Bjerre ,  Cody Eric Bünger ,  Flemming Besenbacher

    IPC分类号： A61F2/00

    CPC分类号： C12N5/0602 ,  A61L27/34 ,  A61L27/56 ,  C12N2533/20 ,  C12N2533/50

    摘要： A method of making a three-dimensional biocompatible scaffold capable of supporting cell activities such as growth and differentiation, the method includes providing a supporting grid that forms an open network and provides mechanical support of a second biocompatible material. The second biocompatible material has interconnected cavities that allow nutrients, metabolites and soluble factors to diffuse throughout the scaffold. The scaffold design can be understood as a hierarchically organised structure. At the micron to submicron length scale a top/down manufacturing approach is used to make a structure that will constitute the frame into which a bottom/up processing approach is applied to form an open porous scaffold with specific nano sized features. The advantage of this hierarchically organised design is that benefits can be drawn independently from both the micron and the nano sized structures, promoting specific cell activities and providing sufficient mechanical compliance.

    摘要翻译： 制备能够支持细胞活性如生长和分化的三维生物相容性支架的方法包括提供形成开放网络并提供第二生物相容性材料的机械支撑的支撑网格。 第二种生物相容性材料具有互连的空腔，其允许营养物，代谢物和可溶性因子在整个支架中扩散。 脚手架设计可以理解为层次结构。 在微米到亚微米长度尺度上，使用顶部/底部制造方法来制造构成框架的结构，其中应用底部/上部加工方法以形成具有特定纳米尺寸特征的开放多孔支架。 这种分级组织设计的优点在于可以独立于微米和纳米尺寸的结构，从而促进特定的细胞活动并提供足够的机械依从性。

    Submerged perfusion bioreactor
    10.
    发明授权
    Submerged perfusion bioreactor 失效
    淹没灌注生物反应器

    公开(公告)号：US08741631B2

    公开(公告)日：2014-06-03

    申请号：US13375785

    申请日：2010-06-03

    申请人： Dang Quang Svend Le ,  Jens Vinge Nygaard ,  Morten Foss ,  Flemming Besenbacher ,  Cody Bünger

    发明人： Dang Quang Svend Le ,  Jens Vinge Nygaard ,  Morten Foss ,  Flemming Besenbacher ,  Cody Bünger

    IPC分类号： C12M1/00 ,  C12M1/02 ,  B01F13/08 ,  C12M3/04 ,  C12M1/06

    CPC分类号： C12M29/10 ,  B01F13/08 ,  B01F13/0827 ,  C12M27/00 ,  C12M27/02 ,  C12M27/10

    摘要： A device for biological purposes such as cell culturing, enzymatic reactions or filtering of fluid has a body with first and second surfaces. The body is delimited by a rim and an aperture in the center of the body. The aperture is covered at the first and second surface by first and second plates. The first and/or second plate has an inlet orifice allowing liquid medium into the aperture. Rotating means are arranged in the aperture between the first and second plate. At least one recessed portion is a cavity in the rim of the body having a first outlet orifice allowing the liquid medium to flow out of the body. At least one outlet channel connects the circular aperture with the recessed portion. Liquid is pumped into the aperture of the device and pumped through at least one outlet channel.

    摘要翻译： 用于生物学目的的装置如细胞培养，酶反应或流体过滤具有具有第一和第二表面的主体。 身体由身体中心的边缘和孔限定。 孔由第一和第二板覆盖在第一和第二表面。 第一和/或第二板具有允许液体介质进入孔的入口孔。 旋转装置布置在第一和第二板之间的孔中。 至少一个凹部是本体边缘中的空腔，其具有允许液体介质从身体流出的第一出口孔。 至少一个出口通道将圆形孔与凹部连接。 液体被泵送到设备的孔中并泵送通过至少一个出口通道。