公开(公告)号：US06518369B2

公开(公告)日：2003-02-11

申请号：US09993115

申请日：2001-11-14

申请人： Thomas Scholl ,  Werner Obrecht ,  Wilfried Braubach ,  Ellen Giebeler ,  Michael Grün ,  Axel Müller ,  Mabel Graf

发明人： Thomas Scholl ,  Werner Obrecht ,  Wilfried Braubach ,  Ellen Giebeler ,  Michael Grün ,  Axel Müller ,  Mabel Graf

IPC分类号： C08L7102

CPC分类号： C08L15/00 ,  C08C19/44 ,  C08G65/337 ,  C08L71/02 ,  C08L2205/05 ,  Y02T10/862 ,  C08L2666/04

摘要： The present invention relates to filled rubber mixes made from polyether/diolefin rubbers. The rubber mixes according to the present invention are suitable for the production of highly reinforced, abrasion-resistant moldings, in particular for the production of tires which exhibit low rolling resistance and elevated wet skid resistance.

公开(公告)号：US06207757B1

公开(公告)日：2001-03-27

申请号：US09365227

申请日：1999-07-30

申请人： Werner Obrecht ,  Thomas Scholl ,  Peter Wendling ,  Michael Well ,  Victor Monroy

发明人： Werner Obrecht ,  Thomas Scholl ,  Peter Wendling ,  Michael Well ,  Victor Monroy

IPC分类号： C08K334

CPC分类号： C08L7/00 ,  B60C1/0016 ,  C08K5/54 ,  C08K5/5415 ,  C08L7/02 ,  C08L19/003 ,  C08L21/00 ,  Y02T10/862 ,  Y10T152/10495 ,  C08L2666/08

摘要： A rubber composition which contains a rubber mixture that can be vulcanized with a vulcanizing agent, which includes at least one rubber component, at least one filler having nucleophilic groups, gel particles comprising a rubber, having a particle size between about 3×10−9 and about 1×10−6 m and a swelling index in toluene of about 1 to about 15 and whose surface has electrophilic centers, and a substance acting as a coupling agent between the filler having nucleophilic groups and the additional filler, the substance acting as a coupling agent having the following structure: X—R1—Si—(R2)3, wherein X is a nucleophilic group, R1 is an alkyl group having up to about 6 carbon atoms or a phenyl group, and R2 may be the same as or different from each other and from R1 and is an alkyl or alkoxy group having up to 6 carbon atoms and at least one of R2 is an alkoxy group. The rubber composition has improved hysteresis behavior in the vulcanized state so that with the use of this rubber composition in tires, the rolling resistance is reduced and the wet slippage behavior is improved in relation to conventional rubber compositions. A method of adding and blending the rubber composition as well as a composition useful for tire treads and vehicle tires containing the composition are disclosed.

摘要翻译： 一种橡胶组合物，其包含可以用硫化剂硫化的橡胶混合物，其包括至少一种橡胶组分，至少一种具有亲核基团的填料，包含橡胶的凝胶颗粒，其具有约3×10 -9和约 1×10 -6 m，甲苯中的溶胀指数为约1至约15，并且其表面具有亲电子中心，以及作为在具有亲核基团的填料和附加填料之间的偶联剂的物质，作为偶联剂的物质具有 以下结构：X-R1-Si-（R2）3，其中X是亲核基团，R1是具有高达约6个碳原子的烷基或苯基，R2可以相同或不同 另一个和R 1是具有至多6个碳原子的烷基或烷氧基，并且至少一个R2是烷氧基。 橡胶组合物在硫化状态下具有改善的滞后性能，因此通过在轮胎中使用该橡胶组合物，相对于常规橡胶组合物，滚动阻力降低，湿滑动性能得到改善。 公开了一种添加和混合橡胶组合物的方法以及用于轮胎胎面的组合物和含有该组合物的车辆轮胎。

公开(公告)号：US6133364A

公开(公告)日：2000-10-17

申请号：US365225

申请日：1999-07-30

申请人： Werner Obrecht ,  Thomas Scholl ,  Peter Wendling ,  Michael Well ,  Victor Monroy

发明人： Werner Obrecht ,  Thomas Scholl ,  Peter Wendling ,  Michael Well ,  Victor Monroy

IPC分类号： B60C1/00 ,  C08K5/17 ,  C08L7/00 ,  C08L9/00 ,  C08L19/00 ,  C08L21/00 ,  C08J5/10 ,  C08K3/04

CPC分类号： C08L7/00 ,  B60C1/0016 ,  C08K5/17 ,  C08L19/003 ,  C08L21/00 ,  C08L19/006 ,  C08L7/02

摘要： A rubber composition, which contains a rubber mixture that can be vulcanized with a vulcanizing agent, which includes at least one rubber component, at least one filler, gel particles comprising a rubber, having a particle size between about 3.times.10.sup.-9 and about 1.times.10.sup.-6 m and a swelling index in toluene of about 1 to about 15 and whose surface has electrophilic centers, and a substance which acts as a coupling agent between the gel particles and which has the structure A--R--A, wherein A is a nucleophilic group, and R is a saturated or unsaturated hydrocarbon group. The rubber composition has improved hysteresis behavior in the vulcanized state so that when this rubber composition is used in tires, the rolling resistance is reduced and the wet slippage behavior is improved in relation to the conventional rubber compositions. A method of formulating the rubber composition as well as a composition useful for tire treads and vehicle tires containing the composition are disclosed.

摘要翻译： 一种橡胶组合物，其含有可以用硫化剂硫化的橡胶混合物，其包含至少一种橡胶组分，至少一种填料，包含橡胶的凝胶颗粒，其粒度为约3×10 -9至约1×10 -9〜 6μm，甲苯中的溶胀指数为约1〜约15，表面具有亲电子中心，以及作为凝胶粒子之间的偶联剂并具有结构ARA的物质，其中A为亲核基团，R为 是饱和或不饱和烃基。 橡胶组合物在硫化状态下具有改善的滞后性能，使得当该橡胶组合物用于轮胎时，相对于常规橡胶组合物，滚动阻力降低，并且湿滑动性能得到改善。 公开了一种配制橡胶组合物的方法以及用于轮胎胎面的组合物和含有该组合物的车辆轮胎。

公开(公告)号：US06184296B2

公开(公告)日：2001-02-06

申请号：US09007337

申请日：1998-01-14

申请人： Werner Obrecht ,  Thomas Scholl ,  Ulrich Eisele ,  Winfried Jeske

发明人： Werner Obrecht ,  Thomas Scholl ,  Ulrich Eisele ,  Winfried Jeske

IPC分类号： C08L4700

CPC分类号： C08C19/20 ,  C08L21/00 ,  Y02T10/862 ,  C08L2666/08

摘要： The rubber mixtures containing modified rubber gels according to the invention prepared from at least one rubber gel modified with compounds containing sulphur and reactive towards C═C double bonds and at least one rubber containing double bonds are preferable suitable for the production of vulcanizates which have an unusually strong reinforcing action in rubber vulcanizates. The vulcanisates furthermore exhibit unusually low dynamic damping at relatively elevated temperatures. They are thus particularly suitable for the production of low rolling resistance motor vehicle tire treads.

摘要翻译： 含有根据本发明的改性橡胶的橡胶混合物由至少一种用硫化合物改性并且对C = C双键具有反应性和至少一种含有双键的橡胶改性的橡胶凝胶制备，适用于生产硫化橡胶 橡胶硫化橡胶中加强作用异常强劲。 硫化橡胶在相对高的温度下进一步显示出非常低的动态阻尼。 因此，它们特别适用于生产低滚动阻力机动车轮胎胎面。

公开(公告)号：US06734257B2

公开(公告)日：2004-05-11

申请号：US10102761

申请日：2002-03-21

申请人： Heike Windisch ,  Werner Obrecht ,  Cristina Stere ,  Thomas Scholl ,  Oskar Nuyken ,  Lars Friebe ,  Mario Vierle

发明人： Heike Windisch ,  Werner Obrecht ,  Cristina Stere ,  Thomas Scholl ,  Oskar Nuyken ,  Lars Friebe ,  Mario Vierle

IPC分类号： C08L5300

CPC分类号： C08F297/06

摘要： The block copolymers according to the invention which are based on conjugated diolefins and polar monomers and are prepared in the presence of catalysts based on the rare earth metals have a high cis-1,4 content in the polydiene block and, because of their polar polymer part and their non-polar diene polymer part, can be used as agents which impart compatibility in the preparation of vulcanizates with a filler content for the production of tires and tire component in the preparation of thermoplastic elastomers or in the modification of thermoplastics.

摘要翻译： 根据本发明的基于共轭二烯烃和极性单体并且在基于稀土金属的催化剂存在下制备的嵌段共聚物在聚二烯嵌段中具有高顺式-1,4的含量，并且由于它们的极性聚合物 部分和它们的非极性二烯聚合物部分可以用作在制备热塑性弹性体或在热塑性塑料的改性中赋予轮胎和轮胎组分的制备中的填料含量的硫化橡胶制剂相容性的试剂。

公开(公告)号：US06242534B1

公开(公告)日：2001-06-05

申请号：US09365226

申请日：1999-07-30

申请人： Werner Obrecht ,  Thomas Scholl ,  Peter Wendling ,  Michael Well ,  Victor Monroy

发明人： Werner Obrecht ,  Thomas Scholl ,  Peter Wendling ,  Michael Well ,  Victor Monroy

IPC分类号： C08F800

CPC分类号： C08L7/02 ,  B60C1/0016 ,  C08L7/00 ,  C08L19/00 ,  C08L21/00 ,  Y02T10/862 ,  Y10T152/10 ,  Y10T152/10495 ,  Y10T152/10855 ,  C08L2666/08

摘要： A rubber mixture containing at least one rubber component, at least one filler, and conventional additives that it contain at least one first gel as a filler, which is essentially comprised of a rubber, has a particle size of 3×10−9 to 1×10−6 m, and has a swelling index in toluene of 1 to 15, and at least the surface of this gel has acid or base groups, where these groups have not been produced by means of reaction with dithiophosphoric acid, and comprises: a) at least one second gel as an additional filler, which is essentially comprised of a rubber, has a particle size of 3×10−9 to 1×10−6 m, and has a swelling index in toluene of 1 to 15, which is in a position to undergo a neutralization reaction with the acid or base groups of the first gel and/or b) contains at least one substance as an additional additive, which is capable of undergoing a neutralization reaction with the acid or base groups of at least one gel. The rubber mixture demonstrates an improved hysteresis behavior in the vulcanized state so that, with the use of this rubber mixture in tires, for example, the rolling resistance is reduced and the wet slippage behavior is improved in relation to the conventional rubber mixture. Methods of formulating such rubber mixtures are also provided.

摘要翻译： 包含至少一种橡胶组分，至少一种填料和常规添加剂的橡胶混合物，其含有至少一种基本上由橡胶组成的填料的第一凝胶具有3×10 -9至1×10 -6 并且在甲苯中的溶胀指数为1至15，并且至少该凝胶的表面具有酸或碱基，其中这些基团未通过与二硫代磷酸反应产生，并且包括：a）至少 基本上由橡胶组成的附加填料的一秒钟凝胶的粒径为3×10 -9〜1×10 -6 m，甲苯中的溶胀指数为1〜15，其处于 与第一凝胶和/ orb的酸或碱基的中和反应）含有至少一种作为另外的添加剂的物质，其能够与至少一种凝胶的酸或碱基进行中和反应。橡胶混合物显示 v。改进的滞后行为 硫化状态使得通过使用轮胎中的这种橡胶混合物，例如，相对于常规的橡胶混合物，滚动阻力降低，并且湿滑滑动性能得到改善。还提供了配制这种橡胶混合物的方法。

公开(公告)号：US6127488A

公开(公告)日：2000-10-03

申请号：US5966

申请日：1998-01-12

申请人： Werner Obrecht ,  Thomas Scholl ,  Ulrich Eisele ,  Winfried Jeske ,  Peter Wendling ,  Adolf Schmidt

发明人： Werner Obrecht ,  Thomas Scholl ,  Ulrich Eisele ,  Winfried Jeske ,  Peter Wendling ,  Adolf Schmidt

IPC分类号： B60C1/00 ,  C08L9/06 ,  C08L19/00 ,  C08L21/00 ,  C08F12/08 ,  B60C11/00 ,  C08F36/06 ,  C08L9/00 ,  C08Y3/40

CPC分类号： C08L7/02 ,  C08L19/003 ,  C08L21/00 ,  Y10S152/905

摘要： Rubber mixtures prepared from at least one styrene/butadiene rubber gel and at least one rubber which contains double bonds and optionally further fillers and rubber auxiliary substances are in particular suitable for the preparation of vulcanizates having unusually high damping at temperatures of from -20 to +20.degree. C. as well as unusually low damping at temperatures of from 40 to 80.degree. C. The rubber mixtures may therefore be used, for example, to manufacture vehicle tires which grip in the wet and have low rolling resistance.

摘要翻译： 由至少一种苯乙烯/丁二烯橡胶凝胶制备的橡胶混合物和至少一种含有双键和任选的其它填料和橡胶辅助物质的橡胶特别适用于制备具有非常高的阻尼的硫化橡胶，其温度为-20至+ 20℃，以及在40至80℃的温度下的非常低的阻尼。因此，橡胶混合物可用于例如制造车辆轮胎，该车辆轮胎处于湿润且具有低滚动阻力。

公开(公告)号：US09361426B2

公开(公告)日：2016-06-07

申请号：US12945227

申请日：2010-11-12

申请人： Viatcheslav R. Akmaev ,  Brant Hendrickson ,  Thomas Scholl

发明人： Viatcheslav R. Akmaev ,  Brant Hendrickson ,  Thomas Scholl

IPC分类号： C12Q1/68 ,  G06F19/18 ,  G06F19/24

CPC分类号： C12Q1/6851 ,  C12Q1/686 ,  C12Q1/6883 ,  C12Q2600/112 ,  C12Q2600/156 ,  C12Q2600/16 ,  G06F19/18 ,  G06F19/24 ,  C12Q2537/16 ,  C12Q2537/165

摘要： Systems and methods for analyzing copy number of a target locus, detecting a disease associated with abnormal copy number of a target gene or a carrier thereof.

摘要翻译： 用于分析目标基因座的拷贝数的系统和方法，检测与靶基因的异常拷贝数相关的疾病或其载体。

公开(公告)号：US20130292310A1

公开(公告)日：2013-11-07

申请号：US13261693

申请日：2011-11-19

申请人： Richard Eberle ,  Micha Kreibig ,  Thomas Scholl ,  Markus Dewes ,  Sven Brall

发明人： Richard Eberle ,  Micha Kreibig ,  Thomas Scholl ,  Markus Dewes ,  Sven Brall

IPC分类号： B01D35/00

CPC分类号： B01D35/005 ,  B01D29/58 ,  B01D35/30 ,  B01D35/306 ,  B01D36/006 ,  B01D2201/295 ,  B01D2201/309 ,  B01D2201/34 ,  F02M37/22

摘要： The invention relates to a filter device, in particular for fluids contaminated with water admixtures, such as diesel oil, comprising a filter housing (1), which can hold at least one filter element (9), the fiber medium (11) of which separates an untreated side (13) from a treated side (19) during the filtration process in the filter housing (1), wherein a water collecting unit (5) is provided, which holds separated water on the treated side, wherein said filter device is characterized in that water that has been separated on the untreated side (13) also reaches the collecting unit (5) and in that mutually separated collecting chambers (61, 67) are present in the collecting unit (5) for the water that is discharged both at the treated side (19) and at the untreated side (13).

摘要翻译： 本发明涉及一种过滤装置，特别是对于被水混合物（例如柴油）污染的流体，该过滤装置包括可容纳至少一个过滤元件（9）的过滤器壳体（1），其中的纤维介质（11） 在过滤器壳体（1）的过滤过程中将未处理侧（13）与处理侧（19）分离，其中提供集水单元（5），其在处理侧保持分离的水，其中所述过滤装置 其特征在于，在未处理侧（13）上分离的水也到达收集单元（5），并且在收集单元（5）中存在相互分离的收集室（61,67） 在处理侧（19）和未处理侧（13）都排出。

公开(公告)号：US20120083597A1

公开(公告)日：2012-04-05

申请号：US13245265

申请日：2011-09-26

申请人： Patricia Okamoto ,  Jan Lawrence Godoski, JR. ,  Thomas Scholl

发明人： Patricia Okamoto ,  Jan Lawrence Godoski, JR. ,  Thomas Scholl

IPC分类号： C07H1/08

CPC分类号： C12N15/1003

摘要： The present invention provides, among other things, a simple, reproducible, and cost-effective method for enriching fetal or other low molecular weight nucleic acids in a biological sample. In certain embodiments, methods are provided for enriching fetal nucleic acids (e.g., fetal DNAs), typically comprising steps of adding a polymer such as PEG to a heterogeneous biological sample containing fetal DNA and high molecular weight non-fetal DNA such that the PEG precipitates substantially the high molecular weight non-fetal DNA, and purifying the fetal DNA from supernatant, thereby enriching the fetal DNA.

摘要翻译： 本发明尤其提供了一种用于富集生物样品中的胎儿或其他低分子量核酸的简单，可重现和成本有效的方法。 在某些实施方案中，提供了用于富集胎儿核酸（例如胎儿DNA）的方法，通常包括将聚合物如PEG加入到含有胎儿DNA和高分子量非胎儿DNA的异质生物样品中的步骤，使得PEG沉淀 基本上是高分子量非胎儿DNA，并从上清液中纯化胎儿DNA，从而富集胎儿DNA。