Method for the determination of the activity of serine proteases or
serine protease inhibitors
    2.
    发明授权
    Method for the determination of the activity of serine proteases or serine protease inhibitors 失效
    确定丝氨酸蛋白酶或丝氨酸蛋白酶抑制剂活性的方法

    公开(公告)号:US5057414A

    公开(公告)日:1991-10-15

    申请号:US214258

    申请日:1988-07-01

    IPC分类号: C12Q1/37 C12Q1/56

    摘要: The invention relates to a method for the determination of the activity of serine proteases and serine protease inhibitors in plasma or other biological fluids.The only methods hitherto available for rapid and accurate determination of the content of serine proteases or serine protease inhibitors have been very time-consuming and methodologically demanding. In the method according to the invention for the determination of the activity of serine proteases or serine protease inhibitors, specific inhibitors are inactivated by addition of at least one oxidizing agent and, where appropriate, at least one detergent. The addition of an omega-aminocarboxylic acid enhances and observed effects when the serine protease is plasmin.

    摘要翻译: 本发明涉及一种测定血浆或其他生物流体中丝氨酸蛋白酶和丝氨酸蛋白酶抑制剂的活性的方法。 迄今唯一可用于快速和准确测定丝氨酸蛋白酶或丝氨酸蛋白酶抑制剂的方法已经非常耗时且方法上要求很高。 在根据本发明的用于确定丝氨酸蛋白酶或丝氨酸蛋白酶抑制剂的活性的方法中,通过加入至少一种氧化剂和适当的话至少一种洗涤剂来使特异性抑制剂失活。 当丝氨酸蛋白酶是纤溶酶时,加入ω-氨基羧酸增强和观察效应。

    Plastics material having an improved blood tolerance
    8.
    发明授权
    Plastics material having an improved blood tolerance 失效
    具有改善血液耐受性的塑料材料

    公开(公告)号:US4178329A

    公开(公告)日:1979-12-11

    申请号:US902901

    申请日:1978-05-05

    摘要: What is disclosed is a plastics material adaptable to biomedical uses, the surface of which material at least partially consists of a graft copolymer having a hydrocarbon main chain and side chains grafted thereon, said side chains being polymers comprising at least one vinyl monomer selected from the group consisting of acrylic acid esters of the formulaCF.sub.3 --(CF.sub.2).sub.x --(CH.sub.2).sub.y --O--CO--CH.dbd.CH.sub.2,where x is an integer from 3 to 16 and y is an integer from 1 to 12, vinylene carbonate, N-vinyl alkylamides of the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and each is hydrogen or alkyl having 1 to 6 carbon atoms.

    摘要翻译: 公开的是适用于生物医学用途的塑料材料,其表面至少部分地由具有烃主链和其上接枝的侧链的接枝共聚物组成,所述侧链是包含至少一种乙烯基单体的聚合物,所述乙烯基单体选自 由CF 3 - (CF 2)x - (CH 2)y O-CO-CH = CH 2的丙烯酸酯组成的组,其中x是3至16的整数,y是1至12的整数,碳酸亚乙烯酯,N 乙烯基烷基酰胺,其中R 1和R 2相同或不同,各自为氢或具有1至6个碳原子的烷基。