SWELLABLE BIODEGRADABLE POLYMERIC MATRICES AND METHODS
    9.
    发明申请
    SWELLABLE BIODEGRADABLE POLYMERIC MATRICES AND METHODS 审中-公开
    可变生物可降解的聚合物矩阵和方法

    公开(公告)号:US20120114589A1

    公开(公告)日:2012-05-10

    申请号:US13125521

    申请日:2009-10-22

    IPC分类号: A61L31/06 A61P41/00 C08B30/18

    摘要: The invention provides biodegradable polymeric hydrogel matrices having excellent durability and swellability. The matrices are formed from a combination of poly-α(1→4)glucopyranose macromer and a biocompatible biostable hydrophilic macromer. The matrices can be used in association with a medical device or alone. In some methods the polymeric matrix is placed or formed at a target site in which the matrix swells and occludes the target area, and is able to be degraded at the target site after period of time.

    摘要翻译: 本发明提供具有优异的耐久性和溶胀性的可生物降解的聚合物水凝胶基质。 基质由poly-α(1→4)吡喃葡萄糖大分子单体和生物相容性生物稳定的亲水大分子单体的组合形成。 矩阵可以与医疗装置或单独使用。 在一些方法中,聚合物基质被放置或形成在其中基质膨胀并封闭目标区域的靶位点,并且能够在一段时间后在靶位点降解。

    Swellable hydrogel matrix and methods
    10.
    发明申请
    Swellable hydrogel matrix and methods 审中-公开
    可膨胀的水凝胶基体和方法

    公开(公告)号:US20090123519A1

    公开(公告)日:2009-05-14

    申请号:US12291622

    申请日:2008-11-12

    IPC分类号: A61F2/02 A61K47/32

    摘要: The invention provides biocompatible polymeric hydrogel matrices having excellent durability and swellability. The matrices are formed from a macromer and photo-polymer combination. The matrices can be used in association with a medical device or alone. In some methods the polymeric matrix is placed or formed at a target site in which the matrix swells and occludes the target area.

    摘要翻译: 本发明提供具有优异耐久性和溶胀性的生物相容性聚合物水凝胶基质。 基质由大分子单体和光聚合物组合形成。 矩阵可以与医疗装置或单独使用。 在一些方法中,聚合物基质被放置或形成在其中基质膨胀并封闭目标区域的靶位点。