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公开(公告)号：US08540632B2
公开(公告)日：2013-09-24
申请号：US12126792
申请日：2008-05-23
IPC分类号： A61B5/07
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： Low profile antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include low profile signal transmission antennas configured such that they are flexible or degrade after use, allowing the antenna and attached components to pass easily through the body. Embodiments of the low profile antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译： 提供用于可摄取装置的低轮廓天线，例如可摄取事件标记。 本发明的可摄取装置的方面包括配置成在使用后它们是柔性的或降级的低轮廓信号传输天线，允许天线和附接的部件容易地穿过身体。 低轮廓天线的实施例被配置为在与目标生理部位接触时发出可检测信号。 还提供了制造和使用本发明的装置的方法。
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公开(公告)号：US20130002423A1
公开(公告)日：2013-01-03
申请号：US13345518
申请日：2012-01-06
IPC分类号： G06K7/01
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： RFID antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include RFID signal transmission antennas with a battery that is activated upon being exposed to fluid in the body. Embodiments of the RFID antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译： 提供了可摄取装置的RFID天线，例如可摄取事件标记。 本发明的可摄取装置的方面包括具有电池的RFID信号传输天线，其在暴露于身体中的流体时被激活。 RFID天线的实施例被配置为在与目标生理部位接触时发出可检测信号。 还提供了制造和使用本发明的装置的方法。
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公开(公告)号：US08115618B2
公开(公告)日：2012-02-14
申请号：US12126798
申请日：2008-05-23
IPC分类号： G08B1/08
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： RFID antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include RFID signal transmission antennas with a battery that is activated upon being exposed to fluid in the body. Embodiments of the RFID antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译： 提供了可摄取装置的RFID天线，例如可摄取事件标记。 本发明的可摄取装置的方面包括具有电池的RFID信号传输天线，其在暴露于身体中的流体时被激活。 RFID天线的实施例被配置为在与目标生理部位接触时发出可检测信号。 还提供了制造和使用本发明的装置的方法。
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公开(公告)号：US20080183072A1
公开(公告)日：2008-07-31
申请号：US11664340
申请日：2007-03-30
申请人： Timothy L. Robertson , George M. Savage , Todd Thompson , Mark J. Zdeblick , Olivier Colliou , Benedict J. Costello
发明人： Timothy L. Robertson , George M. Savage , Todd Thompson , Mark J. Zdeblick , Olivier Colliou , Benedict J. Costello
IPC分类号： A61B5/05
CPC分类号： A61B5/1107 , A61B5/0031 , A61B5/686 , A61B8/12 , A61B8/488 , A61B8/56 , A61B2562/046 , A61N1/3627 , A61N1/365
摘要： Methods for evaluating motion of a tissue, such as of a cardiac location, e.g., heart wall, via continuous field tomography are provided. In the subject methods, a continuous field (e.g., an electrical, mechanical, electro-mechanical, or other field) sensing element is stably associated with the tissue location. A property of the applied continuous field is detected with the sensing element to evaluate movement of the tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译： 提供了通过连续场断层摄影评估诸如心脏位置（例如心脏壁）的组织运动的方法。 在主题方法中，连续场（例如，电，机械，机电或其他场）感测元件与组织位置稳定地相关联。 使用感测元件检测所施加的连续场的属性，以评估组织位置的运动。 还提供了用于实践主题方法的系统，装置和相关组合物。 主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。
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公开(公告)号：US20080316020A1
公开(公告)日：2008-12-25
申请号：US12126798
申请日：2008-05-23
IPC分类号： H04Q7/00
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： RFID antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include RFID signal transmission antennas with a battery that is activated upon being exposed to fluid in the body. Embodiments of the RFID antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译： 提供了可摄取装置的RFID天线，例如可摄取事件标记。 本发明的可摄取装置的方面包括具有电池的RFID信号传输天线，其在暴露于身体中的流体时被激活。 RFID天线的实施例被配置为在与目标生理部位接触时发出可检测信号。 还提供了制造和使用本发明的装置的方法。
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公开(公告)号：US20080306360A1
公开(公告)日：2008-12-11
申请号：US12126792
申请日：2008-05-23
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： Low profile antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include low profile signal transmission antennas configured such that they are flexible or degrade after use, allowing the antenna and attached components to pass easily through the body. Embodiments of the low profile antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译： 提供用于可摄取装置的低轮廓天线，例如可摄取事件标记。 本发明的可摄取装置的方面包括配置成在使用后它们是柔性的或降级的低轮廓信号传输天线，允许天线和附接的部件容易地穿过身体。 低轮廓天线的实施例被配置为在与目标生理部位接触时发出可检测信号。 还提供了制造和使用本发明的装置的方法。
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公开(公告)号：US20080242976A1
公开(公告)日：2008-10-02
申请号：US11664468
申请日：2007-03-30
申请人： Timothy L. Robertson , Olivier Colliou , Benedict J. Costello , George M. Savage , Todd Thompson , Mark J. Zdeblick
发明人： Timothy L. Robertson , Olivier Colliou , Benedict J. Costello , George M. Savage , Todd Thompson , Mark J. Zdeblick
IPC分类号： A61B5/04
CPC分类号： A61B5/1107 , A61B5/686 , A61B2562/046 , A61N1/056 , A61N1/3627 , A61N1/36514 , A61N1/36578 , A61N1/368 , A61N1/3684 , A61N1/375 , A61N1/3752 , A61N1/3756 , A61N2001/0585
摘要： Methods for evaluating motion of a tissue, such as of a cardiac location, e.g., heart wall, via continuous field tomography are provided. In the subject methods, a continuous field (e.g., an electrical, mechanical, electromechanical, or other field) sensing element is stably associated with the tissue location. A property of the applied continuous field is detected with the sensing element to evaluate movement of the tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译： 提供了通过连续场断层摄影评估诸如心脏位置（例如心脏壁）的组织运动的方法。 在主题方法中，连续场（例如，电，机械，机电或其他场）感测元件与组织位置稳定地相关联。 使用感测元件检测所施加的连续场的属性，以评估组织位置的运动。 还提供了用于实践主题方法的系统，装置和相关组合物。 主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。
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8.发明授权公开(公告)号：US08036743B2
公开(公告)日：2011-10-11
申请号：US11909786
申请日：2006-03-31
申请人： George M. Savage , Todd Thompson , Mark J. Zdeblick , Lawrence W. Arne , Olivier Colliou , Benedict James Costello , Fataneh A. Omidvar
发明人： George M. Savage , Todd Thompson , Mark J. Zdeblick , Lawrence W. Arne , Olivier Colliou , Benedict James Costello , Fataneh A. Omidvar
IPC分类号： A61N1/39
CPC分类号： A61N1/3627 , A61N1/08 , A61N1/36185 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/3686 , A61N1/37247
摘要： One embodiment of the present invention provides a system for automatically optimizing CRT procedures using a multi-electrode pacing lead. During operation, the system performs a first set of iterations to select one or more satellites on one or more pacing leads inserted in a patient. A pacing lead includes a plurality of pacing satellites, and a pacing satellite includes a plurality of electrodes that can be individually addressed and used for transmitting or detecting electric signals. The system then performs a second set of iterations to select one or more electrodes on the selected satellites. The system further performs a third set of iterations to select one or more timing configurations for pacing signals transmitted through one or more of the selected electrodes.
摘要翻译： 本发明的一个实施例提供一种用于使用多电极起搏引线自动优化CRT程序的系统。 在操作期间，系统执行第一组迭代以在插入患者体内的一个或多个起搏引线上选择一个或多个卫星。 起搏引线包括多个起搏卫星，并且起搏卫星包括多个电极，其可单独寻址并用于发送或检测电信号。 然后，系统执行第二组迭代以选择所选卫星上的一个或多个电极。 该系统进一步执行第三组迭代以选择一个或多个定时配置，用于通过一个或多个所选择的电极传输的起搏信号。
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公开(公告)号：US08121687B2
公开(公告)日：2012-02-21
申请号：US11718201
申请日：2005-10-31
申请人： Marc Jensen , Todd Thompson , Olivier Colliou , George M. Savage , Mark J. Zdeblick , Jeremy Frank , Lawrence W. Arne , Robert White
发明人： Marc Jensen , Todd Thompson , Olivier Colliou , George M. Savage , Mark J. Zdeblick , Jeremy Frank , Lawrence W. Arne , Robert White
IPC分类号： A61N1/18
CPC分类号： A61N1/056 , A61B5/1107 , A61B5/6851 , A61B5/6857 , A61B5/6858 , A61B5/686 , A61B2562/0266 , A61N1/08 , A61N1/3627
摘要： Methods for evaluating motion of a cardiac tissue location, e.g., heart wall, are provided. In the subject methods, timing of a signal obtain from a strain gauge stably associated with the tissue location of interest is employed to evaluate movement of the cardiac tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译： 提供了用于评估心脏组织位置例如心脏壁的运动的方法。 在本方法中，采用从与感兴趣的组织位置稳定相关联的应变仪获得的信号的定时来评估心脏组织位置的运动。 还提供了用于实践主题方法的系统，装置和相关组合物。 主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。
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公开(公告)号：US20090018632A1
公开(公告)日：2009-01-15
申请号：US12171986
申请日：2008-07-11
申请人： Mark J. Zdeblick , Olivier Colliou
发明人： Mark J. Zdeblick , Olivier Colliou
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/3627 , A61N1/36578
摘要： Aspects of the invention include design rule mediated lead placement methods. Also disclosed are methods of using the resultant positioned leads, e.g., e.g., during evaluation of tissue motion, such as of a cardiac tissue motion, e.g., heart wall motion, via electric tomography, are provided. Also provided are devices and systems for practicing the subject methods. In certain embodiments, innovative data processing and display protocols, as well as systems that provided for the same, are provided. The subject methods, devices and systems find use in a variety of different applications, such as cardiac related applications, e.g., cardiac resynchronization therapy, and other applications.
摘要翻译： 本发明的方面包括设计规则介导的铅放置方法。 还公开了使用所得到的定位引线的方法，例如，例如在评估组织运动期间，例如通过电断层摄影术的心脏组织运动，例如心脏壁运动。 还提供了用于实践主题方法的装置和系统。 在某些实施例中，提供了创新的数据处理和显示协议以及为其提供的系统。 主题方法，装置和系统可用于各种不同的应用，例如心脏相关应用，例如心脏再同步治疗和其它应用。
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