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公开(公告)号：US06924097B1
公开(公告)日：2005-08-02
申请号：US09368572
申请日：1999-08-05
CPC分类号： C12N15/8223 , C12N9/1051
摘要： A plant promoter capable of inducing the expression specifically at the site and stage wherein the reconstitution of plant cell wall xyloglucan is necessary, namely, a plant promoter originating in a gene which encodes an endo-xyloglucan transferase or a gene which encodes a substance having a function equivalent thereto; and a method for modifying the function of a plant with the use of the plant promoter and a method for cloning the plant promoter.
摘要翻译： 需要在植物细胞壁木葡聚糖重构的位点和阶段特异性诱导表达的植物启动子，即来源于编码木糖葡聚糖转移酶的基因的植物启动子或编码具有 功能等同于 以及使用植物启动子修饰植物功能的方法和用于克隆植物启动子的方法。
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公开(公告)号：US6028250A
公开(公告)日：2000-02-22
申请号：US913842
申请日：1997-09-30
IPC分类号： A01H1/00 , C12N9/10 , C12N15/29 , C12N15/82 , C12P21/06 , C12Q1/68 , A01H4/00 , A01H5/00 , C12N5/04
CPC分类号： C12N15/8223 , C12N9/1051
摘要： A plant promoter capable of inducing the expression specifically at the site and stage wherein the reconstitution of plant cell wall xyloglucan is necessary, namely, a plant promoter originating in a gene which encodes an endo-xyloglucan transferase or a gene which encodes a substance having a function equivalent thereto; and a method for modifying the function of a plant with the use of the plant promoter and a method for cloning the plant promoter.
摘要翻译： PCT No.PCT / JP96 / 00777 Sec。 371日期：1997年9月30日 102（e）日期1997年9月30日PCT 1996年3月26日PCT公布。 WO96 / 30509 PCT出版物 日期1996年10月3日能够在需要重新构建植物细胞壁木葡聚糖的部位和阶段特异性诱导表达的植物启动子，即来自编码木糖内切葡聚糖转移酶的基因的植物启动子或基因， 编码具有等同于其的功能的物质; 以及使用植物启动子修饰植物功能的方法和用于克隆植物启动子的方法。
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公开(公告)号：US07449568B2
公开(公告)日：2008-11-11
申请号：US10503467
申请日：2003-02-26
申请人： Satoru Fukuda , Naotsune Saga , Toshiharu Ohba , Sawako Nagashima , Shuichi Takahashi , Kiyozo Asada , Ikunoshin Kato
发明人： Satoru Fukuda , Naotsune Saga , Toshiharu Ohba , Sawako Nagashima , Shuichi Takahashi , Kiyozo Asada , Ikunoshin Kato
CPC分类号： C12N15/823 , C07K14/405 , C07K14/415 , C12N15/8223
摘要： A promoter, an intron and a terminator by which a useful foreign gene can be efficiently expressed in algae and which are thus useful in breeding algae using genetic engineering techniques.
摘要翻译： 启动子，内含子和终止子，有用的外源基因可以在藻类中有效表达，因此可用于使用基因工程技术培育藻类。
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公开(公告)号：US20060234368A1
公开(公告)日：2006-10-19
申请号：US10503467
申请日：2003-02-26
申请人： Satoru Fukuda , Naotsune Saga , Toshiharu Ohba , Sawako Nagashima , Shuichi Takahashi , Kiyozo Asada , Ikunoshin Kato
发明人： Satoru Fukuda , Naotsune Saga , Toshiharu Ohba , Sawako Nagashima , Shuichi Takahashi , Kiyozo Asada , Ikunoshin Kato
CPC分类号： C12N15/823 , C07K14/405 , C07K14/415 , C12N15/8223
摘要： A promoter, an intron and a terminator by which a useful foreign gene can be efficiently expressed in algae and which are thus useful in breeding algae using genetic engineering techniques.
摘要翻译： 启动子，内含子和终止子，有用的外源基因可以在藻类中有效表达，因此可用于使用基因工程技术培育藻类。
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5.发明授权Enhancement of retroviral gene transduction employing polypeptides comprising the fibronectin heparin II binding domain 失效使用包含纤连蛋白肝素II结合结构域的多肽增强逆转录病毒基因转导公开(公告)号：US07790849B2
公开(公告)日：2010-09-07
申请号：US12241581
申请日：2008-09-30
申请人： Kiyozo Asada , Takashi Uemori , Takashi Ueno , Nobuto Koyama , Kimikazu Hashino , Ikunoshin Kato
发明人： Kiyozo Asada , Takashi Uemori , Takashi Ueno , Nobuto Koyama , Kimikazu Hashino , Ikunoshin Kato
CPC分类号： C12N15/86 , A61K48/00 , C07K14/505 , C07K14/78 , C07K2319/00 , C12N9/1088 , C12N2740/13043 , C12N2740/13045
摘要： An isolated polypeptide includes the amino acid sequence shown in SEQ. ID No. 13 and an isolated nucleic acid encoding the polypeptide, such as an isolated nucleic acid including the nucleic acid sequence shown in SEQ. ID No. 17. The isolated polypeptide includes two heparin binding polypeptides connected in tandem and the isolated nucleic acid encodes these. The polypeptide and nucleic acid sequences can improve retroviral vector mediated gene transfer efficiency into target cells.
摘要翻译： 分离的多肽包括SEQ ID NO：1所示的氨基酸序列。 ID号13和编码该多肽的分离的核酸，例如分离的核酸，包括SEQ ID NO：1所示的核酸序列。 分离的多肽包括串联连接的两个肝素结合多肽，分离的核酸编码这些。 多肽和核酸序列可以改进逆转录病毒载体介导的靶细胞的基因转移效率。
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公开(公告)号：US20060269999A1
公开(公告)日：2006-11-30
申请号：US11500480
申请日：2006-08-08
IPC分类号： C12P21/06 , C07K14/195 , C12N15/74 , C07H21/04 , C12N1/21
CPC分类号： C07K14/195
摘要： Isolated DNAs which are DNAs having a base sequence represented by any of SEQ ID NOS:1 to 6 in Sequence Listing or fragments thereof and showing a stationary phase-specific promoter activity in gram positive bacteria.
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公开(公告)号：US20060030046A1
公开(公告)日：2006-02-09
申请号：US11181091
申请日：2005-07-14
申请人： Kiyozo Asada , Takashi Uemori , Takashi Ueno , Nobuto Koyama , Kimikazu Hashino , Ikunoshin Kato
发明人： Kiyozo Asada , Takashi Uemori , Takashi Ueno , Nobuto Koyama , Kimikazu Hashino , Ikunoshin Kato
IPC分类号： C12N15/867 , C07K14/50
CPC分类号： C12N15/86 , A61K48/00 , C07K14/505 , C07K14/78 , C07K2319/00 , C12N9/1088 , C12N2740/13043 , C12N2740/13045
摘要： A polypeptide represented by SEQ. ID No. 13, a polypeptide represented by SEQ. ID No. 30 or functional equivalents thereof and a polypeptide represented by SEQ. ID No. 17.
摘要翻译： SEQ ID NO： SEQ ID NO：13，SEQ ID NO： SEQ ID No 30或其功能等同物和SEQ ID NO： ID号17。
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公开(公告)号：US20050048480A1
公开(公告)日：2005-03-03
申请号：US10333015
申请日：2001-07-18
申请人： Yasuhhiro Tsubosa , Kazuhiko Aoyagi , Hiroki Sasaki , Masaaki Terada , Junichi Mineno , Kiyozo Asada , Ikunoshin Kato
发明人： Yasuhhiro Tsubosa , Kazuhiko Aoyagi , Hiroki Sasaki , Masaaki Terada , Junichi Mineno , Kiyozo Asada , Ikunoshin Kato
IPC分类号： C12N15/12 , C12Q1/68 , C12Q1/6837 , C12Q1/6886
CPC分类号： C12Q1/6886 , C12Q1/6837 , C12Q2600/158
摘要： To provide a method for selecting a marker gene useful for cancer classification; a method for classifying cancer using the gene; a method for detecting cancer; a kit usable for the classification method or detection method; and a DNA array carrying the gene. According to the present invention, there can be obtained a gene, wherein expression of the above gene is altered independently from genes each of which expression is altered specifically during cell proliferation and expression level of the above gene is specifically altered depending on every type of cancer samples to be tested, whereby the classification or detection of cancer can be carried out conveniently and quickly without giving surgical treatment. Therefore, the present invention is useful for the diagnosis, the treatment, and the like of cancer.
摘要翻译： 提供选择用于癌症分类的标记基因的方法; 使用该基因分类癌症的方法; 一种检测癌症的方法; 可用于分类方法或检测方法的试剂盒; 和携带该基因的DNA阵列。 根据本发明，可以获得上述基因的表达独立于在细胞增殖期间特异性改变的基因的各基因的变化，并且根据每种类型的癌症特异性地改变上述基因的表达水平 待测试的样品，从而可以方便快捷地进行癌症的分类或检测，而无需外科治疗。 因此，本发明对癌症的诊断，治疗等有用。
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9.发明授权Hyperthermostable .beta.-galactosidase gene, enzyme encoded thereby, and process for production 失效超热稳定性β-半乳糖苷酶基因，由此编码的酶，以及生产方法
公开(公告)号：US5744345A
公开(公告)日：1998-04-28
申请号：US489733
申请日：1995-06-14
申请人： Atsushi Shimada , Miki Odate , Nobuto Koyama , Kimikazu Hashino , Kiyozo Asada , Ikunoshin Kato
发明人： Atsushi Shimada , Miki Odate , Nobuto Koyama , Kimikazu Hashino , Kiyozo Asada , Ikunoshin Kato
CPC分类号： C12Y302/01023 , C12N9/2471
摘要： An isolated hyperthermostable .beta.-galactosidase gene derived from Pyrococcus furiosus is described. Examples include DNA sequences shown in SEQ ID NO. 2 and SEQ ID NO. 4 and DNAs hybridizable with these DNAs. A method of cloning the hyperthermostable .beta.-galactosidase gene in which each of the above sequences or portions thereof is used as a probe or primer is described. A process for producing a hyperthermostable .beta.-galactosidase by culturing a transformant into which a plasmid containing each of the above genes has been introduced is described. A particularly preferred gene encodes an SDS-resistant hyperthermostable .beta.-galactosidase.
摘要翻译： 描述了源自激烈热球菌的分离的超热稳定性β-半乳糖苷酶基因。 实例包括SEQ ID NO： 2和SEQ ID NO。 4和DNA可与这些DNA杂交。 描述了将上述每个上述序列或其部分用作探针或引物的克隆超热稳定性β-半乳糖苷酶基因的方法。 描述了通过培养其中已经引入了含有上述每种基因的质粒的转化体来生产超热稳定性β-半乳糖苷酶的方法。 特别优选的基因编码SDS-抗性超热稳定性β-半乳糖苷酶。
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10.发明授权Proteins comprising calmodulin- and actin-binding human caldesmon polypeptide fragments 失效蛋白质包含钙调蛋白和肌动蛋白结合的人钙二聚体多肽片段
公开(公告)号：US5532337A
公开(公告)日：1996-07-02
申请号：US285440
申请日：1994-08-04
申请人： Ken'ichiro Hayashi , Takashi Hashida , Kiyozo Asada , Hirokazu Kotani , Ikunoshin Kato , Kenji Sobue
发明人： Ken'ichiro Hayashi , Takashi Hashida , Kiyozo Asada , Hirokazu Kotani , Ikunoshin Kato , Kenji Sobue
IPC分类号： A61K38/00 , A61K31/00 , A61P35/00 , C07K14/435 , C07K14/47 , C12N15/09 , C12N15/12 , C12P21/02 , C12R1/19 , G01N33/53 , C07K14/46 , C07K19/00
CPC分类号： C07K14/47
摘要： Provided are functional peptide fragments of human caldesmon having calmodulin and actin-binding activity, the amino acid sequences and nucleic acid sequences therefor.
摘要翻译： 提供具有钙调素和肌动蛋白结合活性的人钙调蛋白的功能性肽片段，其氨基酸序列及其核酸序列。
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