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公开(公告)号:US20220054704A1
公开(公告)日:2022-02-24
申请号:US17466239
申请日:2021-09-03
Applicant: Trustees of Tufts College
Inventor: David L. Kaplan , Ung-Jin Kim , Jaehyung Park , Hyoung-Joon Jin
IPC: A61L27/22 , A61L27/36 , A61L27/38 , A61L27/52 , A61L27/56 , C07K14/435 , C08J3/07 , C08J3/075 , C08J5/18 , C08J9/00 , C08J9/26 , C08J9/28 , C08L89/00 , D01D5/00 , D01F4/02 , B29C39/00 , B29C39/20 , B29C55/00 , B29D7/01
Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
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公开(公告)号:US09623147B2
公开(公告)日:2017-04-18
申请号:US14293308
申请日:2014-06-02
Applicant: Trustees of Tufts College
Inventor: David L. Kaplan , Ung-Jin Kim , Jaehyung Park , Hyoung-Joon Jin
IPC: A61L27/22 , A61L27/36 , A61L27/38 , A61L27/52 , C07K14/435 , C08J3/07 , C08J3/075 , C08J5/18 , C08J9/00 , C08J9/26 , C08J9/28 , C08L89/00 , D01D5/00 , D01F4/02 , B29C39/00 , B29C39/20 , B29C55/00 , B29D7/01 , B29L7/00 , B29L9/00
CPC classification number: A61L27/227 , A61L27/3604 , A61L27/38 , A61L27/52 , A61L27/56 , A61L2430/02 , B29C39/003 , B29C39/203 , B29C55/005 , B29D7/01 , B29K2089/00 , B29L2007/00 , B29L2009/00 , C07K14/43536 , C07K14/43586 , C08J3/07 , C08J3/075 , C08J5/18 , C08J9/0061 , C08J9/26 , C08J9/28 , C08J2201/0444 , C08J2201/0504 , C08J2205/022 , C08J2389/00 , C08L89/00 , D01D5/0007 , D01F4/02 , Y10T428/249921 , Y10T442/10 , Y10T442/60
Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
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公开(公告)号:US20200282106A1
公开(公告)日:2020-09-10
申请号:US16406538
申请日:2019-05-08
Applicant: Trustees of Tufts College
Inventor: David L. Kaplan , Ung-Jin Kim , Jaehyung Park , Hyoung-Joon Jin
IPC: A61L27/22 , A61L27/36 , A61L27/38 , A61L27/52 , A61L27/56 , C07K14/435 , C08J3/07 , C08J3/075 , C08J5/18 , C08J9/00 , C08J9/26 , C08J9/28 , C08L89/00 , D01D5/00 , D01F4/02 , B29C39/00 , B29C39/20 , B29C55/00 , B29D7/01
Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
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公开(公告)号:US20170296696A1
公开(公告)日:2017-10-19
申请号:US15434484
申请日:2017-02-16
Applicant: Trustees of Tufts College
Inventor: David L. Kaplan , Ung-Jin Kim , Jaehyung Park , Hyoung-Joon Jin
IPC: A61L27/22 , D01D5/00 , A61L27/36 , A61L27/38 , A61L27/52 , A61L27/56 , B29C39/00 , B29C39/20 , B29C55/00 , B29D7/01 , C07K14/435 , C08L89/00 , C08J9/28 , C08J9/26 , C08J9/00 , C08J5/18 , C08J3/075 , C08J3/07 , D01F4/02 , B29L7/00 , B29L9/00
CPC classification number: A61L27/227 , A61L27/3604 , A61L27/38 , A61L27/52 , A61L27/56 , A61L2430/02 , B29C39/003 , B29C39/203 , B29C55/005 , B29D7/01 , B29K2089/00 , B29L2007/00 , B29L2009/00 , C07K14/43536 , C07K14/43586 , C08J3/07 , C08J3/075 , C08J5/18 , C08J9/0061 , C08J9/26 , C08J9/28 , C08J2201/0444 , C08J2201/0504 , C08J2205/022 , C08J2389/00 , C08L89/00 , D01D5/0007 , D01F4/02 , Y10T428/249921 , Y10T442/10 , Y10T442/60
Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
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公开(公告)号:US11129921B2
公开(公告)日:2021-09-28
申请号:US16406538
申请日:2019-05-08
Applicant: Trustees of Tufts College
Inventor: David L. Kaplan , Ung-Jin Kim , Jaehyung Park , Hyoung-Joon Jin
IPC: A61L27/22 , C07K14/435 , C08J3/07 , C08J5/18 , C08J9/00 , C08J9/28 , C08L89/00 , D01F4/02 , B29C39/00 , B29D7/01 , A61L27/36 , A61L27/38 , A61L27/52 , A61L27/56 , C08J3/075 , C08J9/26 , D01D5/00 , B29C55/00 , B29C39/20 , B29L7/00 , B29L9/00
Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
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公开(公告)号:US10314938B2
公开(公告)日:2019-06-11
申请号:US15434484
申请日:2017-02-16
Applicant: Trustees of Tufts College
Inventor: David L. Kaplan , Ung-Jin Kim , Jaehyung Park , Hyoung-Joon Jin
IPC: B29D7/01 , B29L7/00 , B29L9/00 , C08J3/07 , C08J5/18 , C08J9/00 , C08J9/26 , C08J9/28 , D01D5/00 , D01F4/02 , A61L27/22 , A61L27/36 , A61L27/38 , A61L27/52 , A61L27/56 , B29C39/00 , B29C39/20 , B29C55/00 , C08J3/075 , C08L89/00 , C07K14/435
Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
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7.
公开(公告)号:US08742069B2
公开(公告)日:2014-06-03
申请号:US13827304
申请日:2013-03-14
Applicant: Trustees of Tufts College
Inventor: David L. Kaplan , Ung-Jin Kim , Jaehyung Park , Hyoung-Joon Jin
IPC: C07K14/00
CPC classification number: A61L27/227 , A61L27/3604 , A61L27/38 , A61L27/52 , A61L27/56 , A61L2430/02 , B29C39/003 , B29C39/203 , B29C55/005 , B29D7/01 , B29K2089/00 , B29L2007/00 , B29L2009/00 , C07K14/43536 , C07K14/43586 , C08J3/07 , C08J3/075 , C08J5/18 , C08J9/0061 , C08J9/26 , C08J9/28 , C08J2201/0444 , C08J2201/0504 , C08J2205/022 , C08J2389/00 , C08L89/00 , D01D5/0007 , D01F4/02 , Y10T428/249921 , Y10T442/10 , Y10T442/60
Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
Abstract translation: 本发明提供浓缩的水性丝素蛋白溶液和用于制备浓缩的丝心蛋白溶液的全水模式,避免使用有机溶剂,直接添加剂或刺激性化学品。 本发明进一步提供了这些溶液在生产例如纤维,薄膜,泡沫,网眼,支架和水凝胶的材料中的用途。
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公开(公告)号:US20130190222A1
公开(公告)日:2013-07-25
申请号:US13827304
申请日:2013-03-14
Applicant: TRUSTEES OF TUFTS COLLEGE
Inventor: David L. Kaplan , Ung-Jin Kim , Jaehyung Park , Hyoung-Joon Jin
IPC: C07K14/435
CPC classification number: A61L27/227 , A61L27/3604 , A61L27/38 , A61L27/52 , A61L27/56 , A61L2430/02 , B29C39/003 , B29C39/203 , B29C55/005 , B29D7/01 , B29K2089/00 , B29L2007/00 , B29L2009/00 , C07K14/43536 , C07K14/43586 , C08J3/07 , C08J3/075 , C08J5/18 , C08J9/0061 , C08J9/26 , C08J9/28 , C08J2201/0444 , C08J2201/0504 , C08J2205/022 , C08J2389/00 , C08L89/00 , D01D5/0007 , D01F4/02 , Y10T428/249921 , Y10T442/10 , Y10T442/60
Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
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