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    MONOCLONAL ANTIBODIES FOR TREATMENT OF CANCER
    1.
    发明申请
    MONOCLONAL ANTIBODIES FOR TREATMENT OF CANCER 有权
    用于治疗癌症的单克隆抗体

    公开(公告)号：US20130071325A1

    公开(公告)日：2013-03-21

    申请号：US13636277

    申请日：2011-03-10

    申请人： Ugur Sahin ,  Ozlem Tureci ,  Michael Koslowski ,  Rita Mitnacht-Kraus

    发明人： Ugur Sahin ,  Ozlem Tureci ,  Michael Koslowski ,  Rita Mitnacht-Kraus

    IPC分类号： C07K16/30

    CPC分类号： C07K16/30 ,  A61K39/39558 ,  A61K2039/505 ,  C07K16/462 ,  C07K16/464 ,  C07K2317/14 ,  C07K2317/34 ,  C07K2317/73 ,  C07K2317/76 ,  C12N5/163 ,  C12N15/1138 ,  C12N2310/14

    摘要： The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast cancer, lung cancer, gastric cancer, ovarian cancer, hepatocellular cancer, colon cancer, pancreatic cancer, esophageal cancer, head & neck cancer, kidney cancer, in particular renal cell carcinoma, prostate cancer, liver cancer, melanoma, sarcoma, myeloma, neuroblastoma, placental choriocarcinoma, cervical cancer, and thyroid cancer, and the metastatic forms thereof. In one embodiment, the tumor disease is metastatic cancer in the lung.

    摘要翻译： 本发明提供了可用作治疗和/或预防与表达GT468的细胞相关的疾病的治疗剂的抗体，包括肿瘤相关疾病如乳腺癌，肺癌，胃癌，卵巢癌，肝细胞癌，结肠癌，胰腺癌，食管癌 癌症，头颈癌，肾癌，特别是肾细胞癌，前列腺癌，肝癌，黑素瘤，肉瘤，骨髓瘤，成神经细胞瘤，胎盘绒毛膜癌，子宫颈癌和甲状腺癌及其转移形式。 在一个实施方案中，肿瘤疾病是肺中的转移性癌症。

    MONOCLONAL ANTIBODIES FOR TREATMENT OF CANCER
    2.
    发明申请
    MONOCLONAL ANTIBODIES FOR TREATMENT OF CANCER 有权
    用于治疗癌症的单克隆抗体

    公开(公告)号：US20110223182A1

    公开(公告)日：2011-09-15

    申请号：US13119027

    申请日：2009-09-16

    申请人： Ugur Sahin ,  Ozlem Tureci ,  Michael Koslowski ,  Rita Mitnacht-Kraus

    发明人： Ugur Sahin ,  Ozlem Tureci ,  Michael Koslowski ,  Rita Mitnacht-Kraus

    IPC分类号： A61K39/395 ,  C07K16/30 ,  C12N5/16 ,  C12N5/09 ,  A61P35/00 ,  A61P35/04

    CPC分类号： C07K16/30 ,  A61K2039/505 ,  C07K2317/34 ,  C07K2317/73

    摘要： The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast Cancer, lung Cancer, gastric Cancer, ovarian Cancer, hepatocellular Cancer, colon Cancer, pancreatic Cancer, esophageal Cancer, head & neck Cancer, kidney Cancer, in particular renal cell Carcinoma, prostate Cancer, liver cancer, melanoma, sarcoma, myeloma, neuroblastoma, placental choriocarcinoma, cervical cancer, and thyroid Cancer, and the metastatic forms thereof. In one embodiment, the rumor disease is metastatic cancer in the lung.

    摘要翻译： 本发明提供可用作治疗和/或预防与表达GT468的细胞相关疾病的治疗剂的抗体，包括肿瘤相关疾病如乳腺癌，肺癌，胃癌，卵巢癌，肝细胞癌，结肠癌，胰腺癌，食管癌 癌症，头颈癌，肾癌，特别是肾细胞癌，前列腺癌，肝癌，黑素瘤，肉瘤，骨髓瘤，神经母细胞瘤，胎盘绒毛膜癌，子宫颈癌和甲状腺癌及其转移形式。 在一个实施方案中，谣言疾病是肺中的转移性癌症。

    Monoclonal antibodies for treatment of cancer
    3.
    发明授权
    Monoclonal antibodies for treatment of cancer 有权
    用于治疗癌症的单克隆抗体

    公开(公告)号：US08946388B2

    公开(公告)日：2015-02-03

    申请号：US13119027

    申请日：2009-09-16

    申请人： Ugur Sahin ,  Ozlem Tureci ,  Michael Koslowski ,  Rita Mitnacht-Kraus

    发明人： Ugur Sahin ,  Ozlem Tureci ,  Michael Koslowski ,  Rita Mitnacht-Kraus

    IPC分类号： C07K16/00 ,  C07K16/30 ,  A61K39/00

    CPC分类号： C07K16/30 ,  A61K2039/505 ,  C07K2317/34 ,  C07K2317/73

    摘要： The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast Cancer, lung Cancer, gastric Cancer, ovarian Cancer, hepatocellular Cancer, colon Cancer, pancreatic Cancer, esophageal Cancer, head & neck Cancer, kidney Cancer, in particular renal cell Carcinoma, prostate Cancer, liver cancer, melanoma, sarcoma, myeloma, neuroblastoma, placental choriocarcinoma, cervical cancer, and thyroid Cancer, and the metastatic forms thereof. In one embodiment, the rumor disease is metastatic cancer in the lung.

    摘要翻译： 本发明提供可用作治疗和/或预防与表达GT468的细胞相关疾病的治疗剂的抗体，包括肿瘤相关疾病如乳腺癌，肺癌，胃癌，卵巢癌，肝细胞癌，结肠癌，胰腺癌，食管癌 癌症，头颈癌，肾癌，特别是肾细胞癌，前列腺癌，肝癌，黑素瘤，肉瘤，骨髓瘤，神经母细胞瘤，胎盘绒毛膜癌，子宫颈癌和甲状腺癌及其转移形式。 在一个实施方案中，谣言疾病是肺中的转移性癌症。