公开(公告)号：US20210199630A1

公开(公告)日：2021-07-01

申请号：US17057242

申请日：2019-05-20

Applicant: Waters Technologies Corporation

Inventor： Martin Gilar ,  Thomas S. McDonald ,  Joseph D. Michienzi ,  Jeffrey Musacchio ,  Rachel Mumma ,  Keith Fadgen ,  Geoff C. Gerhardt

IPC: G01N30/60 ,  G01N30/06

Abstract: Methods and devices for the washing, extraction, and separation of a sample in a disposable chromatography cartridge (201) comprising a barrel (204) and a column (205), and especially including reinforcement to the column permitting high-pressure separation.

公开(公告)号：US20210033632A1

公开(公告)日：2021-02-04

申请号：US16940595

申请日：2020-07-28

Applicant: Waters Technologies Corporation

Inventor： Jeffrey Musacchio

IPC: G01N35/02 ,  G01N30/02

Abstract: Described is a chain including a plurality of links pivotally connected to each other such that the chain is configured to bend in one direction without back-bending. Each of the plurality of links including a link body include: an inner side facing a bending direction of the chain; an outer side facing opposite the bending direction of the chain; a back-bending prevention portion; a post feature extending laterally across the link body, and a connection feature configured to engage with the post feature of the first other of the pivotally connected plurality of links to create one direction pivotal attachment without back-bending between the links. Further disclosed is a chain system and methods of moving devices with a chain or chain system.

公开(公告)号：US12085584B2

公开(公告)日：2024-09-10

申请号：US16939530

申请日：2020-07-27

Applicant: Waters Technologies Corporation

Inventor： Jeffrey Musacchio

IPC: G01N35/10 ,  G01N35/00 ,  G01N30/20

CPC classification number: G01N35/10 ,  G01N35/0099 ,  G01N30/20 ,  G01N2035/1027 ,  G01N2035/1051

Abstract: Described is a method for loading a sample-vial carrier into a sample manager of a liquid chromatography system. The method includes placing a sample-vial carrier onto a transfer drawer having first and second drawer magnets. The transfer drawer is transported into a sample tray of a sample manager using a drawer drive system of a transfer drawer receiving apparatus. The drawer drive system has a drive magnet that is engaged with the first drawer magnet during transport. The transport of the transfer drawer is terminated when the second drawer magnet is engaged with a sample tray magnet on the sample tray. The sample tray is rotated about an axis substantially perpendicular to a direction of transport of the transfer drawer to provide a shear force to disengage the first drawer magnet from the drive magnet.

公开(公告)号：US12025625B2

公开(公告)日：2024-07-02

申请号：US16939509

申请日：2020-07-27

Applicant: Waters Technologies Corporation

Inventor： Jeffrey Musacchio ,  Scott Kelley

IPC: G01N35/00 ,  G01N35/04 ,  G01N30/24 ,  G01N35/02

CPC classification number: G01N35/00584 ,  G01N35/0099 ,  G01N35/04 ,  G01N30/24 ,  G01N35/026 ,  G01N35/028 ,  G01N2035/042 ,  G01N2035/0422 ,  G01N2035/0429 ,  G01N2035/0465 ,  G01N2035/0484 ,  G01N2035/0498

Abstract: Described is an interface module for robotic loading and unloading of a liquid chromatography sample manager. The module includes a transfer drawer receiving apparatus having a device track and a drawer drive system configured to transport a transfer drawer along the device track into and out from a sample tray of a sample manager. The transfer drawer receives a sample-vial carrier that holds samples to be analyzed. The module further includes a window apparatus that has a window controllable to be in an open state or a closed state. When in the open state, transport of the transfer drawer through the window into or out from the sample manager permits loading of the sample-vial carrier into the sample tray and unloading of the sample-vial carrier from the sample tray. In the closed state, the window apparatus substantially seals the internal environment of the sample manager from the ambient environment.

公开(公告)号：US20210396721A1

公开(公告)日：2021-12-23

申请号：US17354234

申请日：2021-06-22

Applicant: Waters Technologies Corporation

Inventor： Michael O. Fogwill ,  Martin Gilar ,  Joseph D. Michienzi ,  Wade P. Leveille ,  Geoff C. Gerhardt ,  Jeffrey Musacchio ,  Jason F. Hill ,  Sylvain G. Cormier

IPC: G01N30/46 ,  G01N30/32 ,  G01N30/30

Abstract: The exemplary embodiments may provide a collective insulating sleeve for a plurality of chromatography columns or may provide separate insulating sleeve for each of the chromatography columns in a plurality. As a result, column ovens are not needed, and pre-heaters may not be required for each chromatography column in some exemplary embodiments. Thus, parallel column arrangements in the exemplary embodiments may be more compact than conventional arrangements.

公开(公告)号：US20210229119A1

公开(公告)日：2021-07-29

申请号：US17155462

申请日：2021-01-22

Applicant: Waters Technologies Corporation

Inventor： Wade P. Leveille ,  Joseph D. Michienzi ,  Jeffrey Musacchio ,  Emrys Jones ,  Steven Derek Pringle ,  Stephen Hattan ,  Gregory T. Roman

IPC: B05B5/03 ,  B05B12/32

Abstract: A sprayer assembly for an ion source is disclosed. The sprayer includes a capillary having an outlet, a sheath for the capillary, and an elastic member. The sheath can move relative to the capillary between a first position in which the sheath covers the outlet of the capillary and a second position in which the outlet of the capillary is exposed. When the sheath moves from the first position to or towards the second position, the elastic member provides a restoring force that acts to restore the position of the sheath to or towards the first position.

公开(公告)号：US20210033633A1

公开(公告)日：2021-02-04

申请号：US16939530

申请日：2020-07-27

Applicant: Waters Technologies Corporation

Inventor： Jeffrey Musacchio

IPC: G01N35/10 ,  G01N35/00

Abstract: Described is a method for loading a sample-vial carrier into a sample manager of a liquid chromatography system. The method includes placing a sample-vial carrier onto a transfer drawer having first and second drawer magnets. The transfer drawer is transported into a sample tray of a sample manager using a drawer drive system of a transfer drawer receiving apparatus. The drawer drive system has a drive magnet that is engaged with the first drawer magnet during transport. The transport of the transfer drawer is terminated when the second drawer magnet is engaged with a sample tray magnet on the sample tray. The sample tray is rotated about an axis substantially perpendicular to a direction of transport of the transfer drawer to provide a shear force to disengage the first drawer magnet from the drive magnet.

公开(公告)号：US20200088221A1

公开(公告)日：2020-03-19

申请号：US16573439

申请日：2019-09-17

Applicant: Waters Technologies Corporation

Inventor： Jeffrey Musacchio ,  Michael Eggertson ,  Joseph Michienzi

IPC: F15B15/14 ,  G01N30/02 ,  F16H37/08 ,  F15B15/18 ,  F15B1/04

Abstract: A liquid chromatography solvent pump includes at least one motor, a first piston, a second piston, and a continuously variable output drive system coupling the at least one motor to at least one of the first and second pistons. The first piston and the second piston are configured to deliver a flow of solvent in a liquid chromatography system.

公开(公告)号：US20200064312A1

公开(公告)日：2020-02-27

申请号：US16545590

申请日：2019-08-20

Applicant: Waters Technologies Corporation

Inventor： Jeffrey Musacchio ,  Keith Fadgen ,  Joseph D. Michienzi ,  Stanislaw Koziol

IPC: G01N30/16

Abstract: Described is a fluidic manifold that includes a block formed of multiple layers each bonded to at least one adjacent layer at a layer interface. Bonding may be achieved using a diffusion bonding process. The block includes one or more attachment surfaces and at least two fluidic channels. Each fluidic channel is at least partially disposed at one of the layer interfaces and has a first end at one of the attachment surfaces. Each attachment surface includes an attachment feature at the first end of one of the fluidic channels to enable a fluidic coupling of the two fluidic channels through a fluidic component. Attachment features include, for example, a compression fitting coupling body adapted to receive a conventional seal, such as a ferrule and compression screw, and a fitting body that permits a face seal or gasket seal between the fluidic component and the block.

公开(公告)号：US12163934B2

公开(公告)日：2024-12-10

申请号：US17354234

申请日：2021-06-22

Applicant: Waters Technologies Corporation

Inventor： Michael O. Fogwill ,  Martin Gilar ,  Joseph D. Michienzi ,  Wade P. Leveille ,  Geoff C. Gerhardt ,  Jeffrey Musacchio ,  Jason F. Hill ,  Sylvain G. Cormier

IPC: G01N30/46 ,  G01N30/02 ,  G01N30/30 ,  G01N30/32 ,  G01N30/72 ,  G01N30/74

Abstract: The exemplary embodiments may provide a collective insulating sleeve for a plurality of chromatography columns or may provide separate insulating sleeve for each of the chromatography columns in a plurality. As a result, column ovens are not needed, and pre-heaters may not be required for each chromatography column in some exemplary embodiments. Thus, parallel column arrangements in the exemplary embodiments may be more compact than conventional arrangements.