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公开(公告)号：US09671418B2
公开(公告)日：2017-06-06
申请号：US14760100
申请日：2014-01-10
发明人： Colin Mellars , Baris Yagci , Benjamin S. Pollack
CPC分类号： G01N35/04 , B65G17/002 , E21B19/146 , G01N35/00 , G01N35/00732 , G01N35/02 , G01N35/026 , G01N2035/00207 , G01N2035/00801 , G01N2035/0401 , G01N2035/0406 , G01N2035/0412 , G01N2035/042 , G01N2035/0422 , G01N2035/0467 , G01N2035/0493 , Y10T436/113332
摘要： An automation system for use with in vitro diagnostics includes a track configured to provide one or more paths and a plurality of payload carriers having payload carrier types. One or more of the plurality of payload carrier types has a different payload carrier dimension in a direction of travel than another payload carrier type. The system includes a plurality of carriers configured to move along the track in the direction of travel. Each of the plurality of carriers has a substantially identical carrier dimension in the direction of travel and configured to hold any one of the plurality of payload carrier types. The system includes a controller configured to navigate the plurality of carriers along the track based on at least one of: (i) the substantially identical carrier dimension in the direction of travel; and (ii) one or more of the different payload carrier dimensions in the direction of travel.
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公开(公告)号：US09459273B2
公开(公告)日：2016-10-04
申请号：US14117573
申请日：2012-05-11
申请人： Thomas Moix , Guillaume Ding , Michael Eberhardt , Martin Mueller , Sebastian Wiessner , Jurjen Zoethout
发明人： Thomas Moix , Guillaume Ding , Michael Eberhardt , Martin Mueller , Sebastian Wiessner , Jurjen Zoethout
CPC分类号： G01N35/00584 , G01N35/04 , G01N2035/0422 , G01N2035/0467 , G01N2035/0489
摘要： The invention concerns a laboratory product transport element for a laboratory transport system with an energy receiver and/or energy accumulator to provide drive power, at least one signal receiver to receive control signals, a control unit to generate drive signals as a function of at least one control signal obtained from the at least one signal receiver, movement devices for independent movement of the laboratory product transport element on a transfer path as a function of the drive signals of the control unit, in which the drive devices are driven by the drive power and at least one holder to hold a laboratory product being transported. The invention also concerns a laboratory transport system with at least one laboratory product transport element according to an embodiment of the invention and a transfer path arrangement. The invention also concerns methods for operation of laboratory transport systems according to an embodiment of the invention.
摘要翻译： 本发明涉及一种用于具有能量接收器和/或能量累加器以提供驱动功率的实验室输送系统的实验室产品传输元件，至少一个用于接收控制信号的信号接收器，控制单元以至少产生作为至少的功能的驱动信号 从至少一个信号接收器获得的一个控制信号，用于根据控制单元的驱动信号在传送路径上独立移动实验室产品传送元件的移动装置，其中驱动装置由驱动力驱动 和至少一个持有人持有要运输的实验室产品。 本发明还涉及具有根据本发明的实施例的至少一个实验室产品传送元件和传送路径布置的实验室传送系统。 本发明还涉及根据本发明实施例的实验室运输系统的操作方法。
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公开(公告)号：US20150355211A1
公开(公告)日：2015-12-10
申请号：US14760100
申请日：2014-01-10
发明人： Colin Mellars , Baris Yagci , Benjamin S. Pollack
IPC分类号： G01N35/04
CPC分类号： G01N35/04 , B65G17/002 , E21B19/146 , G01N35/00 , G01N35/00732 , G01N35/02 , G01N35/026 , G01N2035/00207 , G01N2035/00801 , G01N2035/0401 , G01N2035/0406 , G01N2035/0412 , G01N2035/042 , G01N2035/0422 , G01N2035/0467 , G01N2035/0493 , Y10T436/113332
摘要： An automation system for use with in vitro diagnostics includes a track configured to provide one or more paths and a plurality of payload carriers having payload carrier types. One or more of the plurality of payload carrier types has a different pay-load carrier dimension in a direction of travel than another payload carrier type. The system includes a plurality of carriers configured to move along the track in the direction of travel. Each of the plurality of carriers has a substantially identical carrier dimension in the direction of travel and configured to hold any one of the plurality of payload carrier types. The system includes a controller configured to navigate the plurality of carriers along the track based on at least one of: (i) the substantially identical carrier dimension in the direction of travel; and (ii) one or more of the different payload carrier dimensions in the direction of travel.
摘要翻译： 用于体外诊断的自动化系统包括配置成提供一个或多个路径的轨道和具有有效载荷类型的多个有效载荷载波。 多个有效载荷载体类型中的一个或多个在行进方向上具有与另一有效载荷载体类型不同的载荷载体尺寸。 该系统包括多个载体，其构造成沿行进方向沿轨道移动。 多个载波中的每一个在行进方向上具有基本上相同的载波尺寸，并被配置为保持多个有效负载载体类型中的任何一个。 该系统包括控制器，其被配置为基于以下至少一个导航多个载体：（i）行进方向上的基本相同的载体尺寸; 和（ii）行进方向上的一个或多个不同有效载荷载体尺寸。
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4.发明申请公开(公告)号：US20110158850A1
公开(公告)日：2011-06-30
申请号：US13057584
申请日：2009-07-13
IPC分类号： B01L9/06
CPC分类号： B01L9/02 , B01L9/06 , B01L2200/025 , B01L2300/022 , G01N35/04 , G01N2035/0422 , G01N2035/0465
摘要： There is disclosed an automated bench (2) for loading/unloading test tubes (1) by means of a test-tube (1) handling device (4) between multi-location racks (3) arranged according to parallel rows (40) lying on said bench (2) and transport devices (5) for transporting individual test tubes (1) that are movable on an automatic conveyor (6) of test tubes (1). Said bench (2) comprises means (14) for transferring multi-location racks (3) towards a test tubes load/unload position (16) and an ordered succession of pistons (17) that is selectively mobile between a lowered rest position and a raised stop position of the rack (3) positioned on the bench (2) so as to stop the rack (3) in successive positions with the rows (40) of the rack (3) occupying in succession said load/unload position (16) of bench (2). A sensor (20) of the bench (2) detects the presence of test tubes (1) in every single row (40) of rack (3) in load/unload position (16).
摘要翻译： 公开了一种用于通过根据平行的行（40）布置的多位置机架（3）之间的试管（1）处理装置（4）来装载/卸载试管（1）的自动化台架（2） 在所述工作台（2）和运送装置（5）上，用于运送在试管（1）的自动输送机（6）上可移动的各个试管（1）。 所述工作台（2）包括用于将多位置机架（3）朝向试管装载/卸载位置（16）传送的装置（14）和有选择地连续的活塞（17），其可选择地在降低的静止位置和 位于台架（2）上的支架（3）的上升停止位置，以便使齿条（3）在架子（3）的行（40）连续占据所述装载/卸载位置（16）的连续位置 ）的长凳（2）。 工作台（2）的传感器（20）检测在装载/卸载位置（16）中机架（3）的每一行（40）中是否存在试管（1）。
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公开(公告)号：US20100049358A1
公开(公告)日：2010-02-25
申请号：US12460821
申请日：2009-07-23
申请人： Bruno Koch , Markus Kurmann , Marcel Lustenberger
发明人： Bruno Koch , Markus Kurmann , Marcel Lustenberger
CPC分类号： G06F17/00 , G01N35/0099 , G01N35/025 , G01N35/026 , G01N35/028 , G01N2035/042 , G01N2035/0422 , G01N2035/0425 , G01N2035/0484
摘要： A method and laboratory system for handling sample tube racks are disclosed. The laboratory system includes a storage section (14) with a plurality of shelves (110) for storing a plurality of storage racks (SR), a disposal unit (18) for disposing sample tubes from the storage racks (SR), a robotic transfer system (510) for loading storage racks (SR) into the storage section (14), for retrieving storage racks (SR) from the storing section (14) and for bringing storage rack to the disposal unit (18) after a given storage time has elapsed.
摘要翻译： 公开了一种用于处理样品管架的方法和实验室系统。 实验室系统包括具有多个用于存储多个存储架（SR）的搁架（110）的存储部分（14），用于从存储架（SR）设置样品管的处理单元（18），机器人传送 系统（510），用于将存储架（SR）装载到存储部分（14）中，用于从存储部分（14）检索存储机架（SR），并且在给定的存储时间之后将存储架带到处理单元（18） 已经过去了
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6.发明申请公开(公告)号：US20080293090A1
公开(公告)日：2008-11-27
申请号：US12117297
申请日：2008-05-08
申请人： Elaine POWERS
发明人： Elaine POWERS
IPC分类号： C12Q1/02
CPC分类号： G01N35/1083 , G01N15/1475 , G01N35/028 , G01N2015/0092 , G01N2015/0693 , G01N2015/1486 , G01N2035/00366 , G01N2035/0422 , G01N2035/103
摘要： An improved liquid handling machine capable of regulating the temperature of assay compounds in the automated preparation of culture trays for biological assays is disclosed. The machine includes a horizontally movable table positioned beneath a vertically movable head. The table is divided into a plurality of stations holding mixing trays, culture trays and reservoirs of liquid assay compound. The head holds a plurality of pipettes which aspirate and expel liquid to transfer and mix the assay compounds between the reservoir, the mixing trays and the culture trays upon coordinated movement of the head and the table as controlled by a microprocessor. Each station on the table has independent heating, cooling and temperature sensing elements for regulating the temperature of the liquid held in a tray or reservoir at the station. A device for automatically evaluating the results of the assay, such as by fluorescence, spectrophotometric or radioactive techniques is incorporated with the improved liquid handling machine.
摘要翻译： 公开了一种改进的液体处理机，其能够在生物测定的培养盘的自动化制备中调节测定化合物的温度。 该机器包括位于可垂直移动的头部下方的可水平移动的工作台。 该台分为多个站，分别容纳液体分析化合物的混合盘，培养皿和储存器。 头部保持多个移液管，其吸取和排出液体，以在由微处理器控制的头部和桌子的协调运动时将储存器，混合托盘和培养托盘之间的测定化合物混合。 桌子上的每个工作台都有独立的加热，冷却和温度检测元件，用于调节保持在车站的托盘或水箱中的液体的温度。 用于通过荧光，分光光度计或放射性技术自动评估测定结果的装置与改进的液体处理机器一起使用。
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7.发明申请公开(公告)号：US20070005169A1
公开(公告)日：2007-01-04
申请号：US10573448
申请日：2004-09-24
申请人： Peter Röhnert , Frank Striggow
发明人： Peter Röhnert , Frank Striggow
IPC分类号： G06F19/00
CPC分类号： G01N35/028 , G01N1/31 , G01N35/0099 , G01N2035/00326 , G01N2035/0422 , G01N2035/0467
摘要： The present invention relates to a device for automatically carrying out laboratory operations on cell or tissue samples, which comprises a plurality of modular stations, each of which carries out at least one operation in a total sequence of operations, and at least one support unit for transporting sample containers to and between the stations, the device having at least one station for automatically changing liquid media in the sample containers.
摘要翻译： 本发明涉及一种用于自动执行细胞或组织样本的实验室操作的装置，其包括多个模块化站，每个模块站在整个操作序列中执行至少一个操作，以及至少一个支撑单元，用于 将样品容器运送到工位之间和之间，该装置具有至少一个用于在样品容器中自动改变液体介质的工位。
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公开(公告)号：US07105132B2
公开(公告)日：2006-09-12
申请号：US10082974
申请日：2002-02-25
IPC分类号： B01L3/02
CPC分类号： B01L9/52 , B01J19/00 , B01J19/0046 , B01J2219/00011 , B01J2219/00315 , B01J2219/00328 , B01J2219/00691 , B01J2219/00695 , B01J2219/007 , B01J2219/00702 , B01J2219/00707 , B01L9/523 , B01L2300/0829 , B01L2300/0893 , C40B60/14 , G01N35/0099 , G01N35/028 , G01N35/1002 , G01N35/1074 , G01N2035/00326 , G01N2035/042 , G01N2035/0422 , G01N2035/0425 , Y10T436/11 , Y10T436/110833 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/25 , Y10T436/2575
摘要： A chemical solution distribution system and method that includes or employs a plurality of liquid handlers where each of the liquid handlers includes a movable table that engages a sample multiwell plate and can align pipettes of the station with different subsets of wells of the multiwell plate where the number of wells of the multiwell plate is a multiple of the number of pipettes of the head of the pipette station. The system further includes and employs four different pumps to enable the system and method to supply four different solutions to wash stations of each of the four liquid handlers.
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公开(公告)号：US06979425B1
公开(公告)日：2005-12-27
申请号：US09699818
申请日：2000-10-30
CPC分类号： B01J19/0046 , B01J2219/00364 , B01J2219/00387 , B01J2219/00531 , B01J2219/00659 , B01J2219/00691 , B01J2219/00693 , B01J2219/00722 , B01L3/0244 , G01N2035/00158 , G01N2035/0422 , Y10T436/112499 , Y10T436/114998 , Y10T436/2575
摘要： A high capacity microarrayer for spotting solution onto slides in an automated microarray dispensing device. A microplate indexing device automatically moves, in sequence, a plurality of microplates to a solution removal area. A dispense head accesses each microplate at the solution removal area to remove solution from the microplate. The dispense head then moves to a slide positioning station to spot slides at the slide positioning station. In a preferred embodiment of the present invention, the microplate indexing station has at least one input stacking chamber for stacking microplates, and at least one output stacking chamber for stacking microplates. A walking beam indexer is disposed between the at least one input stacking chamber and the at least one output stacking chamber. The walking beam indexer is for moving microplates from said at least one input stacking chamber to said at least one output stacking chamber. While at the solution removal area, a lid lifter lifts the lid off each microplate to permit the microplate to be accessed by the dispense head for solution removal. After the solution is removed, the lid lifter replaces the lid. In another preferred embodiment, there is at least one light source capable of illuminating the slides, and at least one camera operating in conjunction with the at least one light source. The at least one camera is capable of acquiring and transmitting slide image data to a computer. The computer is programmed to receive the slide image and analyze it. The computer will then generate post analysis data based on the analysis of the slide image data. The post analysis data is available for improving the spotting of the solution onto the slides. In a preferred embodiment, the slide image data includes information relating to slide alignment, information relating to spot quality, and slide identification information. In a preferred embodiment, the analysis of the information relating to slide alignment enables the computer to make automatic adjustments to the relative positions of the at least one dispense head and the slides to increase the accuracy of the spotting. In a preferred embodiment, the analysis of the information relating to spot quality identifies a spot as pass or fail. An operator is then able to rework the spot. In a preferred embodiment, the analysis of the slide identification information enables the computer to track each slide.
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10.发明申请Device for dispensing and observing the luminescence of individual specimens in multi-specimen arrangements 失效用于分配和观察多标本布置中各个样本的发光的装置公开(公告)号：US20040022689A1
公开(公告)日：2004-02-05
申请号：US10630199
申请日：2003-07-30
申请人： CyBio AG
发明人： Juergen Wulf , Werner Pongratz , Andreas Fina , Michael Heil , Michael Jurtz
IPC分类号： G01N021/00
CPC分类号： G01N35/109 , G01N21/6428 , G01N21/6452 , G01N35/1011 , G01N35/1065 , G01N2021/6443 , G01N2021/6482 , G01N2035/0422
摘要： The invention is directed to a device for dispensing and observing the luminescence of individual specimens in multi-specimen arrangements, particularly for the examination of biological, chemical or cytobiological assays with high specimen throughput. It is the object of the invention to find a novel possibility for dispensing in multi-specimen arrangements (microplates) and for observing the luminescence of the individual specimens, particularly for examining biological assays with high specimen throughput, which permits an immediate observation of the course of luminescence while dispensing proceeds at the same time without being limited to a determined type of microplate. This object is met, according to the invention, in that the dispensing unit has at least one linear dispensing comb containing an even number of dispensing nozzles representing an integral divisor of the number of wells along one dimension of the microplate, the dispensing combs are arranged so as to be displaceable orthogonal to their longitudinal dimension, every dispensing comb is connected to a controllable pump for metering the amount of liquid to be dispensed without immersion in the wells of the microplate, and the CCD camera is oriented by a fast optical system to a large-area rectangular region of the underside of the microplate across from the dispensing unit, the surface being adapted to the dimension of the dispensing comb and to the area of the microplate covered by the dispensing comb, so that the elapsed time for the luminescence is measurable simultaneously while dispensing continues.
摘要翻译： 本发明涉及一种用于分配和观察多个样品装置中的各个样品的发光的装置，特别是用于以高样品生产量检查生物，化学或细胞生物学测定。 本发明的目的是找到一种新型的多样品布置（微孔板）分配和用于观察单个样品的发光的可能性，特别是用于检查具有高样品通量的生物测定法，其允许立即观察该过程 的发光，同时分配在同一时间进行，而不限于确定类型的微孔板。 根据本发明，符合本发明的目的在于，分配单元具有至少一个线性分配梳，其包含偶数个分配喷嘴，分配喷嘴表示沿着微孔板的一个维度的孔数的积分因子，分配梳被布置 为了能够与其纵向尺寸正交地移动，每个分配梳都连接到可控制的泵，用于计量待分配的液体量而不浸没在微板的孔中，并且CCD相机通过快速光学系统定向 微孔板下面的从分配单元的大面积矩形区域，该表面适于分配梳的尺寸和由分配梳覆盖的微板的面积，使得发光的经过时间 可同时测量，同时分配持续。
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