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    ANNULAR COMPRESSION SYSTEMS AND METHODS FOR SAMPLE PROCESSING DEVICES
    2.
    发明申请
    ANNULAR COMPRESSION SYSTEMS AND METHODS FOR SAMPLE PROCESSING DEVICES 审中-公开
    环形压缩系统和样品处理装置的方法

    公开(公告)号：US20110117607A1

    公开(公告)日：2011-05-19

    申请号：US12617905

    申请日：2009-11-13

    申请人： William Bedingham ,  Peter D. Ludowise ,  Jeffrey C. Pederson ,  Barry W. Robole ,  Christopher R. Kokaisel

    发明人： William Bedingham ,  Peter D. Ludowise ,  Jeffrey C. Pederson ,  Barry W. Robole ,  Christopher R. Kokaisel

    IPC分类号： C12P19/34 ,  C12M1/00

    CPC分类号： B01L7/52 ,  B01L2300/0803 ,  B01L2300/1811 ,  B01L2300/1822 ,  B01L2300/1827 ,  B01L2300/1883

    摘要： Systems and methods for processing sample processing devices. The system can include a base plate adapted to rotate about a rotation axis. The base plate can include at least one first magnetic element. The system can further include an annular cover, and a sample processing device comprising at least one thermal process chamber. The annular cover can include an inner edge, an outer edge, and at least one second magnetic element. The method can include positioning the sample processing device between the base plate and the annular cover, such that the inner edge of the annular cover is positioned inwardly of the at least one thermal process chamber, and such that the at least one first magnetic element attracts the at least one second magnetic element to force the annular cover in a first direction along the z-axis, urging the sample processing device into contact with the base plate.

    摘要翻译： 用于处理样品处理装置的系统和方法。 该系统可以包括适于围绕旋转轴线旋转的基板。 基板可以包括至少一个第一磁性元件。 该系统还可以包括环形盖，以及包括至少一个热处理室的样品处理装置。 环形盖可以包括内边缘，外边缘和至少一个第二磁性元件。 该方法可以包括将样品处理装置定位在基板和环形盖之间，使得环形盖的内边缘位于至少一个热处理室的内部，并且使得至少一个第一磁性元件吸引 所述至少一个第二磁性元件沿着z轴沿第一方向推动所述环形盖，迫使所述样品处理装置与所述基板接触。

    Thermal transfer methods and structures for microfluidic systems
    3.
    发明授权
    Thermal transfer methods and structures for microfluidic systems 有权
    微流体系统的热转移方法和结构

    公开(公告)号：US08128893B2

    公开(公告)日：2012-03-06

    申请号：US11962703

    申请日：2007-12-21

    申请人： William Bedingham ,  Christopher R. Kokaisel ,  Jeffrey C. Pederson

    发明人： William Bedingham ,  Christopher R. Kokaisel ,  Jeffrey C. Pederson

    IPC分类号： B01L7/00

    CPC分类号： G01N21/11 ,  B01L3/50273 ,  B01L2300/0806 ,  B01L2300/087 ,  B01L2300/1822 ,  B01L2300/1861 ,  B01L2400/0409 ,  B01L2400/0442 ,  B01L2400/0677 ,  G01N21/07 ,  Y10T137/6579

    摘要： Processing devices that include one or more process arrays with thermal transfer structures that can be used alone or in conjunction with gravity/rotation to transport fluids within a microfluidic system. The thermal transport function can be accomplished by changing the temperature of one or more chambers to create a vacuum to draw fluids in selected directions within the process array. The methods and apparatus of the present invention may provide the ability to move fluids in a direction that is against the direction of gravity or any centrifugal forces generated by rotating a processing device using the thermal transfer structures. In other words, fluids may be moved against the direction of gravity or towards the axis of rotation using the thermally-activated vacuum.

    摘要翻译： 包括具有热转移结构的一个或多个过程阵列的处理装置，其可以单独使用或与重力/旋转结合使用以在微流体系统内输送流体。 热传递功能可以通过改变一个或多个室的温度来实现，以产生真空以在流程阵列内的选定方向抽取流体。 本发明的方法和装置可以提供沿着重力方向移动流体的能力，或者通过使用热传递结构旋转处理装置产生的任何离心力。 换句话说，流体可以使用热活化的真空来抵抗重力方向或朝向旋转轴线移动。

    THERMAL TRANSFER METHODS AND STRUCURES FOR MICROFLUIDIC SYSTEMS
    4.
    发明申请
    THERMAL TRANSFER METHODS AND STRUCURES FOR MICROFLUIDIC SYSTEMS 有权
    微流控系统的热传递方法和结构

    公开(公告)号：US20080149190A1

    公开(公告)日：2008-06-26

    申请号：US11962703

    申请日：2007-12-21

    申请人： William Bedingham ,  Christopher R. Kokaisel ,  Jeffrey C. Pederson

    发明人： William Bedingham ,  Christopher R. Kokaisel ,  Jeffrey C. Pederson

    IPC分类号： F16K49/00

    CPC分类号： G01N21/11 ,  B01L3/50273 ,  B01L2300/0806 ,  B01L2300/087 ,  B01L2300/1822 ,  B01L2300/1861 ,  B01L2400/0409 ,  B01L2400/0442 ,  B01L2400/0677 ,  G01N21/07 ,  Y10T137/6579

    摘要： Processing devices that include one or more process arrays with thermal transfer structures that can be used alone or in conjunction with gravity/rotation to transport fluids within a microfluidic system. The thermal transport function can be accomplished by changing the temperature of one or more chambers to create a vacuum to draw fluids in selected directions within the process array. The methods and apparatus of the present invention may provide the ability to move fluids in a direction that is against the direction of gravity or any centrifugal forces generated by rotating a processing device using the thermal transfer structures. In other words, fluids may be moved against the direction of gravity or towards the axis of rotation using the thermally-activated vacuum.

    摘要翻译： 包括具有热转移结构的一个或多个过程阵列的处理装置，其可以单独使用或与重力/旋转结合使用以在微流体系统内输送流体。 热传递功能可以通过改变一个或多个室的温度来实现，以产生真空以在流程阵列内的选定方向抽取流体。 本发明的方法和装置可以提供沿着重力方向移动流体的能力，或者通过使用热传递结构旋转处理装置产生的任何离心力。 换句话说，流体可以使用热活化的真空来抵抗重力方向或朝向旋转轴线移动。

    Systems for processing sample processing devices
    6.
    发明授权
    Systems for processing sample processing devices 有权
    样品处理装置处理系统

    公开(公告)号：US08834792B2

    公开(公告)日：2014-09-16

    申请号：US12617921

    申请日：2009-11-13

    申请人： Barry W. Robole ,  William Bedingham ,  Peter D. Ludowise ,  Jeffrey C. Pederson

    发明人： Barry W. Robole ,  William Bedingham ,  Peter D. Ludowise ,  Jeffrey C. Pederson

    IPC分类号： G01N9/30 ,  G01N21/00 ,  B01L3/00 ,  B01L7/00

    CPC分类号： B01L3/5027 ,  B01L7/52 ,  B01L2300/046 ,  B01L2300/0803 ,  B01L2300/0861 ,  B01L2300/1883 ,  Y10T436/11

    摘要： A system and method for processing sample processing devices. The system can include a base plate adapted to rotate about a rotation axis. The system can further include a cover including a first projection, and a housing. A portion of the housing can be movable with respect to the base plate between an open position and a closed position, and can include a second projection. The first projection and the second projection can be adapted to be coupled together when the portion is in the open position and decoupled when the portion is in the closed position. The method can include coupling the cover to the portion of the housing, moving the portion of the housing from the open position to the closed position, and rotating the base plate about the rotation axis.

    摘要翻译： 一种处理样品处理装置的系统和方法。 该系统可以包括适于围绕旋转轴线旋转的基板。 该系统还可以包括包括第一突起和壳体的盖。 壳体的一部分可以相对于基板在打开位置和关闭位置之间移动，并且可以包括第二突起。 当该部分处于打开位置时，第一突起和第二突出部可以适于联接在一起，并且当该部分处于关闭位置时该第一突出部和第二突出部分被解耦。 该方法可以包括将盖连接到壳体的部分，将壳体的部分从打开位置移动到关闭位置，并且使基板围绕旋转轴线旋转。

    SYSTEMS AND METHODS FOR PROCESSING SAMPLE PROCESSING DEVICES
    9.
    发明申请
    SYSTEMS AND METHODS FOR PROCESSING SAMPLE PROCESSING DEVICES 有权
    用于处理样品加工装置的系统和方法

    公开(公告)号：US20110117656A1

    公开(公告)日：2011-05-19

    申请号：US12617921

    申请日：2009-11-13

    申请人： Barry W. Robole ,  William Bedingham ,  Peter D. Ludowise ,  Jeffrey C. Pederson

    发明人： Barry W. Robole ,  William Bedingham ,  Peter D. Ludowise ,  Jeffrey C. Pederson

    IPC分类号： G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  B01L7/00

    CPC分类号： B01L3/5027 ,  B01L7/52 ,  B01L2300/046 ,  B01L2300/0803 ,  B01L2300/0861 ,  B01L2300/1883 ,  Y10T436/11

    摘要： A system and method for processing sample processing devices. The system can include a base plate adapted to rotate about a rotation axis. The system can further include a cover including a first projection, and a housing. A portion of the housing can be movable with respect to the base plate between an open position and a closed position, and can include a second projection. The first projection and the second projection can be adapted to be coupled together when the portion is in the open position and decoupled when the portion is in the closed position. The method can include coupling the cover to the portion of the housing, moving the portion of the housing from the open position to the closed position, and rotating the base plate about the rotation axis.

    摘要翻译： 一种处理样品处理装置的系统和方法。 该系统可以包括适于围绕旋转轴线旋转的基板。 该系统还可以包括包括第一突起和壳体的盖。 壳体的一部分可以相对于基板在打开位置和关闭位置之间移动，并且可以包括第二突起。 当该部分处于打开位置时，第一突起和第二突出部可以适于联接在一起，并且当该部分处于关闭位置时该第一突出部和第二突出部分被解耦。 该方法可以包括将盖连接到壳体的部分，将壳体的部分从打开位置移动到关闭位置，并且使基板围绕旋转轴线旋转。

    Biological sterilization indicator system and method
    10.
    发明授权
    Biological sterilization indicator system and method 有权
    生物灭菌指标体系及方法

    公开(公告)号：US09410180B2

    公开(公告)日：2016-08-09

    申请号：US13821647

    申请日：2011-10-28

    申请人： Jeffrey C. Pederson ,  Sailaja Chandrapati ,  Bryan S. Behun ,  Barry W. Robole ,  Leroy J. Longworth ,  Kaileen Chen

    发明人： Jeffrey C. Pederson ,  Sailaja Chandrapati ,  Bryan S. Behun ,  Barry W. Robole ,  Leroy J. Longworth ,  Kaileen Chen

    IPC分类号： C12Q1/00 ,  C12M1/00 ,  C12Q1/22 ,  A61L2/28

    CPC分类号： C12Q1/22 ,  A61L2/28

    摘要： A biological sterilization indicator (BI) system and method. The system can include a BI and a reading apparatus comprising a well. The BI can include a housing, which can include a first portion, and a second portion movable between a first “unactivated” position and a second “activated” position. The reading apparatus can detect at least one of (i) when the well is empty; (ii) when the biological sterilization indicator is positioned in the well with the second portion of the housing in the first position, and (iii) when the biological sterilization indicator is positioned in the well with the second portion of the housing in the second position. The method can include detecting at least one of the above conditions, which can be used to detect an activation status of the biological sterilization indicator.

    摘要翻译： 一种生物灭菌指标（BI）系统及方法。 该系统可以包括BI和包括井的读取装置。 BI可以包括壳体，其可以包括第一部分，以及可在第一“未激活”位置和第二“激活”位置之间移动的第二部分。 读取装置可以检测（i）当井是空的时候的至少一个; （ii）当生物灭菌指示器位于井中时，壳体的第二部分处于第一位置，以及（iii）当生物灭菌指示器位于井中时，壳体的第二部分位于第二位置 。 该方法可以包括检测可用于检测生物灭菌指示剂的活化状态的上述条件中的至少一个。