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公开(公告)号：US5169602A
公开(公告)日：1992-12-08
申请号：US490051
申请日：1990-03-07
申请人： Wing S. Pang , Thomas L. Kraft , James W. Meador
发明人： Wing S. Pang , Thomas L. Kraft , James W. Meador
CPC分类号： G01N35/1079 , A61J1/20 , A61J2200/10 , Y10S215/03
摘要： A resealable conduit is used to remove or add fluid to a closed system without coring or contamination of the fluid. The conduit can include funnel-shaped guide means, duck bill valve means and beveled tip puncturing means. A conduit resting angle of less than about five degrees can be achieved. A tip bevel angle between about ten and twenty degrees is preferred. The beveled tip can have a rotated or twisted blade surface extension. A blade surface extension formed with a ninety degree rotation of the blade surface is preferred. Alternately, the puncturing means can include a needle point or a flat cutting surface.
摘要翻译： 可重新密封的管道用于将流体移除或添加到封闭系统中，而不会使流体取向或污染。 导管可以包括漏斗形引导装置，鸭嘴阀装置和斜角尖端穿刺装置。 可以实现小于约5度的管道静止角度。 优选约十到二十度之间的尖端斜角。 斜面尖端可以具有旋转或扭曲的叶片表面延伸。 优选地，叶片表面延伸形成有叶片表面的九十度旋转。 或者，穿刺装置可以包括针尖或平切面。
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2.发明授权
公开(公告)号：US5162236A
公开(公告)日：1992-11-10
申请号：US512036
申请日：1990-04-13
申请人： Wing S. Pang , Dobson M. Okawa , Peter Kan , George K. Shibata
发明人： Wing S. Pang , Dobson M. Okawa , Peter Kan , George K. Shibata
CPC分类号： G01N21/0332 , G01N35/00 , G01N21/51 , G01N2201/122 , G01N33/53 , Y10S435/808 , Y10S436/808 , Y10S436/909
摘要： A system for analyzing a chemical reaction provides control of the temperature and volume of the reagents to improve the accuracy and precision in quantitative measurements of specific proteins and other immunochemistries in body fluids. The reaction occurs in a cuvette within a nephelometric optics module. A sensor senses the temperatures of reaction buffer liquids as they flow into the cuvette, and a heat exchanging device increases or decreases the temperatures of the buffer liquids. A control circuit responsive to the temperature sensor controls the heat exchanging device to maintain the temperature of the buffer liquids and the cuvette within a selected temperature range. The system may also include a sample pickup station, a sample probe for withdrawing a selected sample from the sample pickup station, a sample preparation station, and a sample transport for carrying said sample from the sample preparation station to the reaction cuvette. The system may include an antibody pickup station, an antibody probe for withdrawing an antibody from the antibody pickup station, an antibody preparation station, and an antibody transport for carrying the antibody from the antibody preparation station to the reaction cuvette.
摘要翻译： 用于分析化学反应的系统提供对试剂的温度和体积的控制，以提高体液中特定蛋白质和其他免疫化学的定量测量的准确性和精确度。 反应发生在浊度计光学模块内的比色皿中。 反应缓冲液体流入比色杯时，传感器检测反应缓冲液的温度，热交换装置增加或减少缓冲液的温度。 响应于温度传感器的控制电路控制热交换装置，以将缓冲液和反应杯的温度保持在所选择的温度范围内。 系统还可以包括样品拾取站，用于从样品拾取站取出选定样品的样品探针，样品制备站和用于将样品从样品制备站运送到反应池的样品输送器。 该系统可以包括抗体拾取站，用于从抗体拾取站取出抗体的抗体探针，抗体制备站和用于将抗体从抗体制备站携带到反应池的抗体转运体。
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公开(公告)号：US4858155A
公开(公告)日：1989-08-15
申请号：US813028
申请日：1985-12-24
申请人： Dobson Okawa , Wing S. Pang , Dang Ngo , George Shibata
发明人： Dobson Okawa , Wing S. Pang , Dang Ngo , George Shibata
CPC分类号： G05D23/1919 , B01L7/00
摘要： Apparatus for controlling reaction temperatures in a chemical analyzer comprises a thermoelectric element operating in response to a temperature sensor, and control means capable of predicting a setpoint deviation for a future time period, and, when an overshoot is predicted, reducing a control signal for the element by an amount proportional to a current setpoint deviation. The apparatus includes at least one reaction cell and a buffer unit for thermally stabilizing a fluid that is fed, on demand, into the reaction cell, the cell and the buffer unit having separate thermoelectric elements and sensors. A microcomputer control system generates independent control signals for the elements.
摘要翻译： 用于控制化学分析仪中的反应温度的装置包括响应于温度传感器工作的热电元件，以及能够预测未来时间段的设定点偏差的控制装置，并且当预测到过冲时，减少控制信号 元素与当前设定值偏差成比例的量。 该装置包括至少一个反应池和缓冲单元，用于热稳定根据需要进料到反应池中的流体，电池和具有分离的热电元件和传感器的缓冲单元。 微机控制系统为元件生成独立的控制信号。
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公开(公告)号：US07141213B1
公开(公告)日：2006-11-28
申请号：US09561627
申请日：2000-05-02
申请人： Wing S. Pang , Mark Gross , Hendra Tanumihardja , Ruediger F. Rauskolb , G. Andrea Pedrazzini , Santiago F. Allen
发明人： Wing S. Pang , Mark Gross , Hendra Tanumihardja , Ruediger F. Rauskolb , G. Andrea Pedrazzini , Santiago F. Allen
CPC分类号： G01N35/0099 , B04B2011/046 , G01N35/0095 , G01N2035/00495 , G01N2035/0405 , G01N2035/0465 , G01N2035/047 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831
摘要： A system for a clinical lab that is capable of automatically processing, including sorting, of multiple specimen containers. The system comprises a central controller, a workstation, one or more analyzers, and an automated centrifuge. The workstation has automatic detectors for detecting the presence of a holder holding specimen containers. The workstation has a bar code reader for reading bar codes on the containers. The system has a transport subsystem, preferably a workstation robotic arm and an analyzer robotic arm for transporting the specimen containers, moving them to and from the workstation, to and from the analyzers, and to and from the centrifuge. The centrifuge is loaded with buckets containing specimen containers. The workstation can be provided with a balance system for balancing the weight of the buckets used. The workstation can also have a decapper for automatically removing caps from the specimen containers.
摘要翻译： 一种用于临床实验室的系统，能够自动处理多个样本容器，包括分选。 该系统包括中央控制器，工作站，一个或多个分析器和自动离心机。 工作站具有自动检测器，用于检测夹持样品容器的存在。 工作站有一个条形码读取器，用于读取容器上的条形码。 该系统具有运输子系统，优选地是工作站机器人手臂和分析器机械手臂，用于运送样本容器，将它们往返于工作站，分离器和从分析器以及从离心机移出和离开。 离心机装有容纳标本容器的桶。 工作站可以设置有平衡系统，用于平衡所使用的铲斗的重量。 工作站还可以有一个拆包器，用于自动从样品容器中取出盖子。
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公开(公告)号：US6060022A
公开(公告)日：2000-05-09
申请号：US887601
申请日：1997-07-03
申请人： Wing S. Pang , Mark Gross , Hendra Tanumihardja , Ruediger F. Rauskolb , G. Andrea Pedrazzini , Santiago F. Allen
发明人： Wing S. Pang , Mark Gross , Hendra Tanumihardja , Ruediger F. Rauskolb , G. Andrea Pedrazzini , Santiago F. Allen
CPC分类号： G01N35/0099 , G01N35/0095 , B04B2011/046 , G01N2035/00495 , G01N2035/047 , G01N35/026 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831
摘要： A system for a clinical lab that is capable of automatically processing, including sorting, of multiple specimen containers. The system comprises a central controller, a workstation, one or more analyzers, and an automated centrifuge. The workstation has automatic detectors for detecting the presence of a holder holding specimen containers. The workstation has a bar code reader for reading bar codes on the containers. The system has a transport subsystem, preferably a workstation robotic arm and an analyzer robotic arm for transporting the specimen containers, moving them to and from the workstation, to and from the analyzers, and to and from the centrifuge. The centrifuge is loaded with buckets containing specimen containers. The workstation can be provided with a balance system for balancing the weight of the buckets used. The workstation can also have a decapper for automatically removing caps from the specimen containers.
摘要翻译： 一种用于临床实验室的系统，能够自动处理多个样本容器，包括分选。 该系统包括中央控制器，工作站，一个或多个分析器和自动离心机。 工作站具有自动检测器，用于检测夹持样品容器的存在。 工作站有一个条形码读取器，用于读取容器上的条形码。 该系统具有运输子系统，优选地是工作站机器人手臂和分析器机械手臂，用于运送样本容器，将它们往返于工作站，分离器和从分析器以及从离心机移出和离开。 离心机装有容纳标本容器的桶。 工作站可以设置有平衡系统，用于平衡所使用的铲斗的重量。 工作站还可以有一个拆包器，用于自动从样品容器中取出盖子。
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公开(公告)号：US4589298A
公开(公告)日：1986-05-20
申请号：US517125
申请日：1983-07-25
申请人： Richard C. Meyer , Wing S. Pang
发明人： Richard C. Meyer , Wing S. Pang
CPC分类号： F16H25/2009 , Y10T74/19623 , Y10T74/19902
摘要： A zero backlash device. The device includes a spring loaded bracket for providing a lateral force to the driving nut on a threaded rod. This lateral force is directed perpendicularly to the axis of the threaded shaft thus insuring continued intimate contact between the threads on the driving nut and the threads on the shaft.
摘要翻译： 零间隙设备。 该装置包括用于向螺杆上的驱动螺母提供横向力的弹簧加载支架。 该横向力垂直于螺纹轴的轴线，从而确保驱动螺母上的螺纹和轴上的螺纹之间的连续紧密接触。
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公开(公告)号：US08038942B2
公开(公告)日：2011-10-18
申请号：US12182958
申请日：2008-07-30
申请人： Wing S. Pang , Mark Gross , Hendra Tanumihardja , Ruediger F. Rauskolb , G. Andrea Pedrazzini , Santiago F. Allen
发明人： Wing S. Pang , Mark Gross , Hendra Tanumihardja , Ruediger F. Rauskolb , G. Andrea Pedrazzini , Santiago F. Allen
CPC分类号： G01N35/0099 , B04B2011/046 , G01N35/0095 , G01N35/026 , G01N2035/00495 , G01N2035/047 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831
摘要： A system for a clinical lab that is capable of automatically processing, including sorting, of multiple specimen containers. The system comprises a central controller, a workstation, one or more analyzers, and an automated centrifuge. The workstation has automatic detectors for detecting the presence of a holder holding specimen containers. The workstation has a bar code reader for reading bar codes on the containers. The system has a transport subsystem, preferably a workstation robotic arm and an analyzer robotic arm for transporting the specimen containers, moving them to and from the workstation, to and from the analyzers, and to and from the centrifuge. The centrifuge is loaded with buckets containing specimen containers. The workstation can be provided with a balance system for balancing the weight of the buckets used. The workstation can also have a decapper for automatically removing caps from the specimen containers.
摘要翻译： 一种用于临床实验室的系统，能够自动处理多个样本容器，包括分选。 该系统包括中央控制器，工作站，一个或多个分析器和自动离心机。 工作站具有自动检测器，用于检测夹持样品容器的存在。 工作站有一个条形码读取器，用于读取容器上的条形码。 该系统具有运输子系统，优选地是工作站机器人手臂和分析器机械手臂，用于运送样本容器，将它们往返于工作站，分离器和从分析器以及从离心机移出和离开。 离心机装有容纳标本容器的桶。 工作站可以设置有平衡系统，用于平衡所使用的铲斗的重量。 工作站还可以有一个拆包器，用于自动从样品容器中取出盖子。
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8.发明授权Method and apparatus for controlling reaction temperature in bio-chemical instruments 有权用于控制生物化学仪器中反应温度的方法和装置公开(公告)号：US07794666B2
公开(公告)日：2010-09-14
申请号：US11349445
申请日：2006-02-07
申请人： William W. Li , Rongchang Xin , Wing S. Pang , Dobson M. Okawa
发明人： William W. Li , Rongchang Xin , Wing S. Pang , Dobson M. Okawa
CPC分类号： G01N1/38 , B01F13/0222 , B01F13/0233 , B01J2219/00495 , B01L7/00 , G01N2035/00425
摘要： Method and apparatus for controlling the temperature of one or more reaction vessels in a bio-chemical analyzer comprises a heat-exchange block, preferably made of cast aluminum or the like, and a thermoelectric device for heating or cooling the block to within a desired temperature range. The heat-transfer block cradles one or more reaction vessels in a thermal energy-transferring relationship, and further supports, in a thermal energy-transferring relationship, one or more fluid conduits serving to transmit a liquid or gas to the interior of the reaction vessels. Preferably, the heat-transfer block is cast from aluminum, and the fluid conduits are disposed inside the casting. By supporting the reaction vessel(s) and fluid conduit(s) in a common block, a single thermoelectric device and controller can be used to simultaneously control the respective temperatures of multiple fluid reagents and/or gases, as well as one or more reaction vessels, thereby reducing the power requirements of the thermal control system.
摘要翻译： 用于控制生物化学分析仪中一个或多个反应容器的温度的方法和装置包括优选由铸铝等制成的热交换块和用于将块加热或冷却至所需温度的热电装置 范围。 热传递块以热能传递关系支撑一个或多个反应容器，并且在热能传递关系中进一步支撑用于将液体或气体传输到反应容器内部的一个或多个流体导管 。 优选地，传热块从铝铸造，并且流体导管设置在铸件内部。 通过将反应容器和流体导管支撑在共同的块中，可以使用单个热电装置和控制器来同时控制多个流体试剂和/或气体的相应温度，以及一个或多个反应 容器，从而降低了热控制系统的功率要求。
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公开(公告)号：US4736638A
公开(公告)日：1988-04-12
申请号：US87179
申请日：1987-08-19
申请人： Dobson Okawa , Wing S. Pang , Peter Kan
发明人： Dobson Okawa , Wing S. Pang , Peter Kan
CPC分类号： G01N35/1083 , G01F23/24 , G01F23/245 , G01N2035/1025
摘要： Apparatus for sensing liquid levels in fluid transfer mechanisms and the like comprises a conductive member supporting containers for sample liquids, the conductive member being rotatably mounted for positioning selected containers under a conductive pipette probe. A low-frequency oscillator is capacitively coupled to the conductive member for generating an alternating electric field and producing an electrical signal at the probe. As the probe is lowered toward the liquid, an amplifier circuit monitors an electrical signal received by the probe. When the probe contacts the liquid, the amplifier detects a signal level in excess of a threshold level and produces an output signal for inhibiting the downward movement of the probe at the moment of contact with the liquid.
摘要翻译： 用于检测流体传送机构等中的液位的装置包括支撑用于样品液体的容器的导电构件，该导电构件可旋转地安装用于将选定的容器定位在导电移液管探针下方。 低频振荡器电容耦合到导电构件，用于产生交变电场并在探针处产生电信号。 当探针朝向液体降低时，放大器电路监测由探头接收的电信号。 当探针接触液体时，放大器检测到超过阈值水平的信号电平，并产生一个输出信号，以阻止在与液体接触的时刻探针向下移动。
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