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1.
公开(公告)号:US20100190753A1
公开(公告)日:2010-07-29
申请号:US12549175
申请日:2009-08-27
申请人: Xianqi KONG , Walter A. Szarek , Francine Gervais
发明人: Xianqi KONG , Walter A. Szarek , Francine Gervais
IPC分类号: A61K31/661 , A61K31/55 , A61K31/495 , A61K31/4418 , A61K31/437 , A61K31/445 , A61K31/4425 , A61K31/4045 , A61K31/223 , A61K31/185 , C07D223/12 , C07D241/04 , C07D471/04 , C07D211/18 , C07D213/82 , C07D211/70 , C07D209/18 , C07C311/46 , C07F9/09 , C07F9/22 , C07C309/01 , C07C307/02 , A61P25/28 , A61P27/02 , A61P3/10
CPC分类号: C07D295/084 , C07C307/02 , C07C309/13 , C07C309/14 , C07C309/15 , C07C309/46 , C07C309/69 , C07C311/32 , C07C311/46 , C07C335/32 , C07C381/02 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/74 , C07D295/088 , C07F9/1651 , C07F9/2458
摘要: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease.
摘要翻译: 描述了治疗或预防淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒。
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2.
公开(公告)号:US07598269B2
公开(公告)日:2009-10-06
申请号:US11807759
申请日:2007-05-30
申请人: Xianqi Kong , Walter A. Szarek , Francine Gervais
发明人: Xianqi Kong , Walter A. Szarek , Francine Gervais
IPC分类号: A61K31/44 , A61K31/47 , C07D211/00
CPC分类号: C07D295/084 , C07C307/02 , C07C309/13 , C07C309/14 , C07C309/15 , C07C309/46 , C07C309/69 , C07C311/32 , C07C311/46 , C07C335/32 , C07C381/02 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/74 , C07D295/088 , C07F9/1651 , C07F9/2458
摘要: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease.
摘要翻译: 描述了治疗或预防淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒。
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3.
公开(公告)号:US07244764B2
公开(公告)日:2007-07-17
申请号:US10871365
申请日:2004-06-18
申请人: Xianqi Kong , Walter A. Szarek , Francine Gervais
发明人: Xianqi Kong , Walter A. Szarek , Francine Gervais
IPC分类号: A61K31/205 , C07C309/00
CPC分类号: C07D295/084 , C07C307/02 , C07C309/13 , C07C309/14 , C07C309/15 , C07C309/46 , C07C309/69 , C07C311/32 , C07C311/46 , C07C335/32 , C07C381/02 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/74 , C07D295/088 , C07F9/1651 , C07F9/2458
摘要: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease.
摘要翻译: 描述了治疗或预防淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒。
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公开(公告)号:US20140329746A1
公开(公告)日:2014-11-06
申请号:US14332675
申请日:2014-07-16
申请人: Xianqi Kong , Xinfu Wu , Abderrahim Bouzide , Isabelle Valade , David Migneault , Francine Gervais , Daniel Delorme , Benoit Bachand , Mohamed Atfani , Sophie Levesque , Bita Samim
发明人: Xianqi Kong , Xinfu Wu , Abderrahim Bouzide , Isabelle Valade , David Migneault , Francine Gervais , Daniel Delorme , Benoit Bachand , Mohamed Atfani , Sophie Levesque , Bita Samim
IPC分类号: C07C309/19 , C07D211/64 , C07D211/52 , C07K5/06 , C07D213/50 , C07D295/088 , C07D211/70 , C07C309/24 , C07D211/14 , C07D213/04
CPC分类号: C07C309/19 , C07C309/14 , C07C309/21 , C07C309/24 , C07C309/26 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/74 , C07D207/12 , C07D207/333 , C07D209/08 , C07D209/16 , C07D209/36 , C07D209/44 , C07D209/48 , C07D209/86 , C07D211/06 , C07D211/14 , C07D211/18 , C07D211/34 , C07D211/48 , C07D211/52 , C07D211/58 , C07D211/64 , C07D211/70 , C07D211/82 , C07D213/04 , C07D213/20 , C07D213/50 , C07D213/75 , C07D213/82 , C07D217/04 , C07D219/10 , C07D231/44 , C07D233/54 , C07D235/28 , C07D257/04 , C07D275/06 , C07D277/66 , C07D295/073 , C07D295/088 , C07D307/14 , C07D307/52 , C07D317/58 , C07D327/04 , C07D327/06 , C07D327/08 , C07D333/20 , C07D333/34 , C07D409/04 , C07D471/04 , C07D471/08 , C07K5/06
摘要: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
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5.
公开(公告)号:US20140107027A1
公开(公告)日:2014-04-17
申请号:US14132898
申请日:2013-12-18
申请人: Xianqi Kong , David Migneault , Isabelle Valade , Xinfu Wu , Francine Gervais
发明人: Xianqi Kong , David Migneault , Isabelle Valade , Xinfu Wu , Francine Gervais
IPC分类号: C07C309/14 , C07K5/087 , C07D453/02 , C07D295/088 , C07D209/18 , C07D257/04
CPC分类号: C07C309/14 , C07C307/02 , C07C309/13 , C07C309/15 , C07C309/19 , C07C309/23 , C07C309/46 , C07C309/69 , C07C311/32 , C07C311/46 , C07C323/25 , C07C323/58 , C07C335/12 , C07C335/32 , C07C381/02 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/74 , C07D209/08 , C07D209/14 , C07D209/18 , C07D209/20 , C07D209/44 , C07D209/48 , C07D211/46 , C07D211/64 , C07D211/70 , C07D217/04 , C07D217/10 , C07D235/28 , C07D257/04 , C07D295/084 , C07D295/088 , C07D317/50 , C07D401/04 , C07D403/04 , C07D403/06 , C07D453/02 , C07D471/04 , C07F9/1651 , C07F9/2458 , C07K5/0812
摘要: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
摘要翻译: 描述了治疗或预防淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒。
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6.
公开(公告)号:US08642801B2
公开(公告)日:2014-02-04
申请号:US12613412
申请日:2009-11-05
申请人: Xianqi Kong , David Migneault , Isabelle Valade , Xinfu Wu , Francine Gervais
发明人: Xianqi Kong , David Migneault , Isabelle Valade , Xinfu Wu , Francine Gervais
IPC分类号: C07C309/19 , A61K31/185
CPC分类号: C07C309/14 , C07C307/02 , C07C309/13 , C07C309/15 , C07C309/19 , C07C309/23 , C07C309/46 , C07C309/69 , C07C311/32 , C07C311/46 , C07C323/25 , C07C323/58 , C07C335/12 , C07C335/32 , C07C381/02 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/74 , C07D209/08 , C07D209/14 , C07D209/18 , C07D209/20 , C07D209/44 , C07D209/48 , C07D211/46 , C07D211/64 , C07D211/70 , C07D217/04 , C07D217/10 , C07D235/28 , C07D257/04 , C07D295/084 , C07D295/088 , C07D317/50 , C07D401/04 , C07D403/04 , C07D403/06 , C07D453/02 , C07D471/04 , C07F9/1651 , C07F9/2458 , C07K5/0812
摘要: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
摘要翻译: 描述了治疗或预防淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒。
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7.
公开(公告)号:US20070010573A1
公开(公告)日:2007-01-11
申请号:US11316694
申请日:2005-12-21
申请人: Xianqi Kong , David Migneault , Isabelle Valade , Xinfu Wu , Francine Gervais
发明人: Xianqi Kong , David Migneault , Isabelle Valade , Xinfu Wu , Francine Gervais
IPC分类号: A61K31/405 , A61K31/277 , A61K31/198 , C07D209/20 , C07C309/13
CPC分类号: C07C309/14 , C07C307/02 , C07C309/13 , C07C309/15 , C07C309/19 , C07C309/23 , C07C309/46 , C07C309/69 , C07C311/32 , C07C311/46 , C07C323/25 , C07C323/58 , C07C335/12 , C07C335/32 , C07C381/02 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/74 , C07D209/08 , C07D209/14 , C07D209/18 , C07D209/20 , C07D209/44 , C07D209/48 , C07D211/46 , C07D211/64 , C07D211/70 , C07D217/04 , C07D217/10 , C07D235/28 , C07D257/04 , C07D295/084 , C07D295/088 , C07D317/50 , C07D401/04 , C07D403/04 , C07D403/06 , C07D453/02 , C07D471/04 , C07F9/1651 , C07F9/2458 , C07K5/0812
摘要: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
摘要翻译: 描述了治疗或预防淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒。
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8.Vaccine for the prevention and treatment of Alzheimer's and amyloid related diseases 审中-公开
标题翻译: 用于预防和治疗阿尔茨海默氏症和淀粉样蛋白相关疾病的疫苗公开(公告)号:US20050090439A1
公开(公告)日:2005-04-28
申请号:US10825958
申请日:2004-04-16
申请人: Robert Chalifour , Lise Hebert , Xianqi Kong , Francine Gervais
发明人: Robert Chalifour , Lise Hebert , Xianqi Kong , Francine Gervais
CPC分类号: A61K39/0007 , A61K2039/505 , C07K14/4711 , C07K16/18
摘要: The present invention relates to a stereochemically based “non-self” antigen vaccine for the prevention and/or treatment of Alzheimer's and other amyloid related diseases. The present invention provides a vaccine for the prevention and treatment of Alzheimer's and other amyloid related diseases, which overcomes the drawbacks associated with using naturally occurring peptides, proteins or immunogens.
摘要翻译: 本发明涉及用于预防和/或治疗阿尔茨海默病和其他淀粉样蛋白相关疾病的基于立体化学的“非自身”抗原疫苗。 本发明提供了用于预防和治疗阿尔茨海默病和其他淀粉样蛋白相关疾病的疫苗,其克服了与使用天然存在的肽,蛋白质或免疫原相关的缺点。
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公开(公告)号:US20100113591A1
公开(公告)日:2010-05-06
申请号:US12613412
申请日:2009-11-05
申请人: Xianqi Kong , David Migneault , Isabelle Valade , Xinfu Wu , Francine Gervais
发明人: Xianqi Kong , David Migneault , Isabelle Valade , Xinfu Wu , Francine Gervais
IPC分类号: A61K31/27 , C07C309/04 , A61K31/16 , C07C53/00 , A61K31/215 , C07C309/65 , A61K31/165 , A61P25/28 , A61P9/00 , A61P17/00
CPC分类号: C07C309/14 , C07C307/02 , C07C309/13 , C07C309/15 , C07C309/19 , C07C309/23 , C07C309/46 , C07C309/69 , C07C311/32 , C07C311/46 , C07C323/25 , C07C323/58 , C07C335/12 , C07C335/32 , C07C381/02 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/74 , C07D209/08 , C07D209/14 , C07D209/18 , C07D209/20 , C07D209/44 , C07D209/48 , C07D211/46 , C07D211/64 , C07D211/70 , C07D217/04 , C07D217/10 , C07D235/28 , C07D257/04 , C07D295/084 , C07D295/088 , C07D317/50 , C07D401/04 , C07D403/04 , C07D403/06 , C07D453/02 , C07D471/04 , C07F9/1651 , C07F9/2458 , C07K5/0812
摘要: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
摘要翻译: 描述了治疗或预防淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒。
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10.
公开(公告)号:US20060223855A1
公开(公告)日:2006-10-05
申请号:US11316693
申请日:2005-12-21
申请人: Xianqi Kong , Xinfu Wu , Abderrahim Bouzide , Isabelle Valade , David Migneault , Francine Gervais , Daniel Delorme , Benoit Bachand , Mohamed Atfani , Sophie Levesque , Bita Samim
发明人: Xianqi Kong , Xinfu Wu , Abderrahim Bouzide , Isabelle Valade , David Migneault , Francine Gervais , Daniel Delorme , Benoit Bachand , Mohamed Atfani , Sophie Levesque , Bita Samim
IPC分类号: A61K31/445 , C07D211/06 , A61K31/185
CPC分类号: C07C309/19 , C07C309/14 , C07C309/21 , C07C309/24 , C07C309/26 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/74 , C07D207/12 , C07D207/333 , C07D209/08 , C07D209/16 , C07D209/36 , C07D209/44 , C07D209/48 , C07D209/86 , C07D211/06 , C07D211/14 , C07D211/18 , C07D211/34 , C07D211/48 , C07D211/52 , C07D211/58 , C07D211/64 , C07D211/70 , C07D211/82 , C07D213/04 , C07D213/20 , C07D213/50 , C07D213/75 , C07D213/82 , C07D217/04 , C07D219/10 , C07D231/44 , C07D233/54 , C07D235/28 , C07D257/04 , C07D275/06 , C07D277/66 , C07D295/073 , C07D295/088 , C07D307/14 , C07D307/52 , C07D317/58 , C07D327/04 , C07D327/06 , C07D327/08 , C07D333/20 , C07D333/34 , C07D409/04 , C07D471/04 , C07D471/08 , C07K5/06
摘要: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
摘要翻译: 描述了治疗或预防淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒。
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