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49 条记录 (耗时 0.047 秒)

    USB head interface device and apparatus thereof
    1.
    发明申请
    USB head interface device and apparatus thereof 有权
    USB头接口装置及其装置

    公开(公告)号：US20140004719A1

    公开(公告)日：2014-01-02

    申请号：US14000307

    申请日：2011-07-25

    申请人： Xiao Feng

    发明人： Xiao Feng

    IPC分类号： H01R35/04

    CPC分类号： H01R35/04 ,  G02F1/136286 ,  G06K19/07732

    摘要： A Universal Serial Bus (USB) head interface device and an apparatus with the USB head interface device are provided. The USB head interface device includes a USB head component (10) and a tension rod base (20). The tension rod base includes: a first locating groove (21) provided on an inner wall of the tension rod base; an elastic fastening member (30) provided on the inner wall of the tension rod base; a tension rod (40) provided in the tension rod base in a stretchable manner, the tension rod includes a first locating rib (41) provided on an outer wall of the tension rod, and the first locating rib is provided with a structure adaptive to the first locating groove; and a rotating shaft (60) which passes through two first through-holes on a second end of the tension rod to connect the tension rod and the USB head component. Wherein, the elastic fastening member is provided with a structure locking a gear (50). A connecting structure between a USB head and a USB body of the USB interface apparatus is simple and is easy to use.

    摘要翻译： 提供通用串行总线（USB）头接口设备和具有USB头接口设备的设备。 USB头接口设备包括USB头组件（10）和张力杆座（20）。 拉杆基座包括：设置在拉杆底座的内壁上的第一定位槽（21） 设置在张力杆底座的内壁上的弹性紧固构件（30） 张力杆（40），其以伸缩方式设置在所述张力杆底座中，所述张力杆包括设置在所述张力杆的外壁上的第一定位肋（41），并且所述第一定位肋具有适于 第一定位槽; 以及旋转轴（60），其通过张紧杆的第二端上的两个第一通孔来连接张紧杆和USB头部件。 其中，弹性紧固构件设置有锁定齿轮（50）的结构。 USB接口设备的USB头和USB主体之间的连接结构简单，易于使用。

    ANTIBODIES TO CD40
    2.
    发明申请
    ANTIBODIES TO CD40 有权
    CD40抗体

    公开(公告)号：US20120225014A1

    公开(公告)日：2012-09-06

    申请号：US13471395

    申请日：2012-05-14

    申请人： Vahe Bedian ,  Ronald P. Gladue ,  Jose Corvalan ,  Xiao-Chi Jia ,  Xiao Feng

    发明人： Vahe Bedian ,  Ronald P. Gladue ,  Jose Corvalan ,  Xiao-Chi Jia ,  Xiao Feng

    IPC分类号： A61K39/395 ,  A61K51/10 ,  A61P35/00 ,  C07K16/28 ,  A61P37/04

    CPC分类号： C07K16/2866 ,  A01K2217/05 ,  A61K39/3955 ,  A61K45/06 ,  A61K48/00 ,  A61K2039/505 ,  A61N5/062 ,  A61N5/10 ,  C07K16/2878 ,  C07K16/40 ,  C07K2317/14 ,  C07K2317/21 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/75 ,  C07K2317/92

    摘要： The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to CD40, preferably human CD40, and that function as CD40 agonists. The invention also relates to human anti-CD40 antibodies and antigen-binding portions thereof. The invention also relates to antibodies that are chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulins derived from human anti-CD40 antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human anti-CD40 antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-CD40 antibodies. The invention also relates to transgenic animals comprising nucleic acid molecules of the present invention.

    摘要翻译： 本发明涉及与CD40，优选人CD40特异性结合并且作为CD40激动剂起作用的抗体及其抗原结合部分。 本发明还涉及人抗CD40抗体及其抗原结合部分。 本发明还涉及嵌合，双特异性，衍生的单链抗体或融合蛋白的部分的抗体。 本发明还涉及衍生自人抗CD40抗体的分离的重链和轻链免疫球蛋白和编码这种免疫球蛋白的核酸分子。 本发明还涉及制备人抗CD40抗体的方法，包含这些抗体的组合物和使用抗体和组合物进行诊断和治疗的方法。 本发明还提供使用编码包含人抗-CD40抗体的重和/或轻免疫球蛋白分子的核酸分子的基因治疗方法。 本发明还涉及包含本发明的核酸分子的转基因动物。

    TRAIL receptor-2 polypeptides and antibodies
    4.
    发明授权
    TRAIL receptor-2 polypeptides and antibodies 有权
    TRAIL受体-2多肽和抗体

    公开(公告)号：US07521048B2

    公开(公告)日：2009-04-21

    申请号：US11512051

    申请日：2006-08-28

    申请人： Brian Gliniak ,  Xiao-Dong Yang ,  Sharon Wong-Madden ,  Ian Foltz ,  Xiao Feng ,  Alison Fitch ,  Stephen Foster ,  Randal R. Ketchem

    发明人： Brian Gliniak ,  Xiao-Dong Yang ,  Sharon Wong-Madden ,  Ian Foltz ,  Xiao Feng ,  Alison Fitch ,  Stephen Foster ,  Randal R. Ketchem

    IPC分类号： C12P21/08 ,  A61K39/00

    CPC分类号： A61K39/39558 ,  A61K38/00 ,  C07K16/2878 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/73 ,  C07K2317/92

    摘要： Polypeptides are provided. Antibodies or antigen binding domains are provided which bind such polypeptides. Also provided are methods of obtaining an antibody that binds tumor necrosis factor (TNF)-related apoptosis-inducing ligand (“TRAIL”) Receptor-2 (TR-2) comprising administering at least one of such polypeptides to an animal and obtaining an antibody that binds TR-2 from the animal. Antibodies reactive with TR-2 are provided. Also provided are cells producing antibodies reactive with TR-2, pharmaceutical compositions comprising antibodies reactive with TR-2, methods using antibodies reactive with TR-2, and kits comprising antibodies reactive with TR-2. Also provided are methods of decreasing or preventing binding of an antibody to TR-2 by administering such a polypeptide.

    摘要翻译： 提供多肽。 提供结合这些多肽的抗体或抗原结合结构域。 还提供了获得结合肿瘤坏死因子（TNF）相关的凋亡诱导配体（“TRAIL”）受体-2（TR-2）的抗体的方法，包括向动物施用至少一种这样的多肽并获得抗体 其结合来自动物的TR-2。 提供与TR-2反应的抗体。 还提供产生与TR-2反应的抗体的细胞，包含与TR-2反应的抗体的药物组合物，使用与TR-2反应的抗体的方法，以及包含与TR-2反应的抗体的试剂盒。 还提供了通过施用这样的多肽来降低或预防抗体与TR-2结合的方法。

    Systems and methods for providing search results based on linguistic analysis
    6.
    发明申请
    Systems and methods for providing search results based on linguistic analysis 审中-公开
    基于语言分析提供搜索结果的系统和方法

    公开(公告)号：US20060161543A1

    公开(公告)日：2006-07-20

    申请号：US11099356

    申请日：2005-04-04

    申请人： Xiao Feng ,  Sky Woo

    发明人： Xiao Feng ,  Sky Woo

    IPC分类号： G06F7/00 ,  G06F17/30

    CPC分类号： G06F16/3344

    摘要： A system and method providing search results based on linguistic analysis is provided. The method comprises receiving content from one or more documents associated with search parameters entered by a user. Language associated with the content based on linguistic parameters is then analyzed. A score is assigned to the content based on the analysis of the language. The content is then ordered by relevance to the user based on the assigned score.

    摘要翻译： 提供了一种基于语言分析提供搜索结果的系统和方法。 该方法包括从与用户输入的搜索参数相关联的一个或多个文档中接收内容。 然后分析与基于语言参数的内容相关联的语言。 基于语言的分析，将内容分配给分数。 然后根据指定的分数与内容相关的内容进行排序。

    Antibodies directed to phospholipase A2 and uses thereof
    8.
    发明申请
    Antibodies directed to phospholipase A2 and uses thereof 审中-公开
    针对磷脂酶A2的抗体及其用途

    公开(公告)号：US20050058649A1

    公开(公告)日：2005-03-17

    申请号：US10726332

    申请日：2003-12-02

    申请人： Gregory Landes ,  Mary Haak-Frendscho ,  Ling Chen ,  Yen-Wah Lee ,  Meina Liang ,  Xiao Feng ,  Xiao-Chi Jia ,  Mark Nocerini

    发明人： Gregory Landes ,  Mary Haak-Frendscho ,  Ling Chen ,  Yen-Wah Lee ,  Meina Liang ,  Xiao Feng ,  Xiao-Chi Jia ,  Mark Nocerini

    IPC分类号： C07K16/40 ,  A61K39/395

    CPC分类号： C07K16/40 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/565

    摘要： The invention described herein relates to antibodies directed to the antigen phospholipase A2 (PLA2) and uses of such antibodies. In particular, in accordance with some embodiments of the invention, there are provided fully human monoclonal antibodies directed to the antigen PLA2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.

    摘要翻译： 本文描述的本发明涉及针对抗原磷脂酶A2（PLA2）的抗体和这种抗体的用途。 特别地，根据本发明的一些实施方案，提供了针对抗原PLA2的完全人单克隆抗体。 编码的核苷酸序列和包含重链和轻链免疫球蛋白分子的氨基酸序列，特别是对应于跨越框架区和/或互补决定区（CDR）的连续重链和轻链序列的序列，特别是从FR1至FR4或CDR1至CDR3 ，提供。 还提供了表达这种免疫球蛋白分子和单克隆抗体的杂交瘤或其它细胞系。