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    System and Method to Managing Stimulation of Select A-Beta Fiber Components
    1.
    发明申请
    System and Method to Managing Stimulation of Select A-Beta Fiber Components 审中-公开

    公开(公告)号：US20190105496A1

    公开(公告)日：2019-04-11

    申请号：US15937427

    申请日：2018-03-27

    申请人： Xiaoyi Min ,  Alexander Kent ,  Richard Williamson

    发明人： Xiaoyi Min ,  Alexander Kent ,  Richard Williamson

    IPC分类号： A61N1/36 ,  A61N1/372 ,  A61N1/05

    摘要： A computer implemented method and system is provided for managing neural stimulation therapy. The method comprises under control of one or more processors configured with program instructions. The method delivers a series of candidate stimulation waveforms having varied stimulation intensities to at least one electrode located proximate to nervous tissue of interest. A parameter defines the candidate stimulation waveforms is changed to vary the stimulation intensity. The method identifies a first candidate stimulation waveform that induces a paresthesia-abatement effect, while continuing to induce a select analgesic effect. The method further identifies a second candidate stimulation waveform that does not induce the select analgesic effect. The method sets a stimulation therapy based on the first and second candidate stimulation waveforms.

    Leadless intra-cardiac medical device with reduced number of feed-thrus
    2.
    发明授权
    Leadless intra-cardiac medical device with reduced number of feed-thrus 有权
    无铅心脏内心脏医疗器械，饲料数量减少

    公开(公告)号：US09008777B2

    公开(公告)日：2015-04-14

    申请号：US13529226

    申请日：2012-06-21

    申请人： Ali Dianaty ,  Gabriel A. Mouchawar ,  Gene A. Bornzin ,  John W. Poore ,  Xiaoyi Min ,  Zoltan Somogyi ,  Richard Williamson

    发明人： Ali Dianaty ,  Gabriel A. Mouchawar ,  Gene A. Bornzin ,  John W. Poore ,  Xiaoyi Min ,  Zoltan Somogyi ,  Richard Williamson

    IPC分类号： A61N1/00 ,  A61N1/375 ,  A61N1/368

    CPC分类号： A61N1/3756 ,  A61B5/042 ,  A61N1/362 ,  A61N1/368 ,  Y10T29/49002

    摘要： A leadless implantable medical device (LIMD) includes a housing formed from a battery and an end cap. A proximal end of the end cap forms an LIMD proximal end and a distal end of the battery case forms an LIMD distal end. A non-conductive coupler mechanically secures a terminal end of the battery case to a mating end of the end cap, while maintaining the battery case and end cap electrically separated. A first electrode projects from the proximal end of the end cap. An intra-cardiac (IC) device extension projects from the distal end of the battery case. The extension includes a second electrode that is electrically connected to the battery case. The second electrode is located remote from the LIMD distal end. An electronics module is located within an internal cavity of the end cap and communicates with the first and second electrodes.

    摘要翻译： 无引线植入式医疗装置（LIMD）包括由电池和端盖形成的壳体。 端盖的近端形成LIMD近端，并且电池壳体的远端形成LIMD远端。 非导电耦合器将电池壳体的终端机械地固定到端盖的配合端，同时保持电池壳体和端盖电气分离。 第一电极从端盖的近端突出。 心脏内（IC）装置延伸部从电池盒的远端伸出。 该延伸部包括电连接到电池壳体的第二电极。 第二电极远离LIMD远端。 电子模块位于端盖的内部空腔内并与第一和第二电极连通。

    Systems and methods for assessing heart failure and controlling cardiac resynchronization therapy using hybrid impedance measurement configurations
    5.
    发明授权
    Systems and methods for assessing heart failure and controlling cardiac resynchronization therapy using hybrid impedance measurement configurations 有权
    用于评估心力衰竭并使用混合阻抗测量配置控制心脏再同步治疗的系统和方法

    公开(公告)号：US08750981B2

    公开(公告)日：2014-06-10

    申请号：US13217554

    申请日：2011-08-25

    申请人： Gene A. Bornzin ,  Xiaoyi Min ,  Laurence S. Sloman ,  Steve Koh

    发明人： Gene A. Bornzin ,  Xiaoyi Min ,  Laurence S. Sloman ,  Steve Koh

    IPC分类号： A61B5/05 ,  A61B5/053 ,  A61N1/36 ,  A61N1/368 ,  A61B5/0205

    CPC分类号： A61B5/053 ,  A61B5/0205 ,  A61B5/0538 ,  A61B5/686 ,  A61N1/36185 ,  A61N1/3627 ,  A61N1/3686

    摘要： Techniques are provided for use with an implantable medical device for detecting and assessing heart failure and for controlling cardiac resynchronization therapy (CRT) based on impedance signals obtained using hybrid impedance configurations. The hybrid configurations exploit right atrial (RA)-based impedance measurement vectors and/or left ventricular (LV)-based impedance measurement vectors. In one example, current is injected between the device case and a ring electrode in the right ventricle (RV) or RA. RA-based impedance values are measured along vectors between the device case and an RA electrode. LV-based impedance values are measured along vectors between the device case and one or more electrodes of the LV. Heart failure and other cardiac conditions are detected and tracked using the measured impedance values. CRT delay parameters are also optimized based impedance. In this manner, multiple hybrid impedance measurement configurations are exploited whereby different vectors are used to inject current and measure impedance.

    摘要翻译： 提供技术用于可植入医疗装置，用于基于使用混合阻抗配置获得的阻抗信号来检测和评估心力衰竭并用于控制心脏再同步治疗（CRT）。 混合配置利用基于右心房（RA）的阻抗测量向量和/或左心室（LV））的阻抗测量向量。 在一个示例中，电流注入到装置壳体和右心室（RV）或RA中的环形电极之间。 基于RA的阻抗值是沿器件壳体和RA电极之间的矢量测量的。 基于LV的阻抗值在器件壳体和LV的一个或多个电极之间的矢量上测量。 使用测量的阻抗值检测和跟踪心力衰竭和其他心脏状况。 CRT延迟参数也是基于阻抗的优化。 以这种方式，利用多个混合阻抗测量配置，由此使用不同的矢量来注入电流并测量阻抗。

    Implantable lead assembly having a plurality of inductors
    7.
    发明授权
    Implantable lead assembly having a plurality of inductors 有权
    具有多个电感器的可植入引线组件

    公开(公告)号：US08600520B2

    公开(公告)日：2013-12-03

    申请号：US13449897

    申请日：2012-04-18

    申请人： Phong D. Doan ,  Xiaoyi Min ,  Virote Indravudh

    发明人： Phong D. Doan ,  Xiaoyi Min ,  Virote Indravudh

    IPC分类号： A61N1/00

    CPC分类号： A61N1/05 ,  A61N1/086 ,  A61N1/3605 ,  A61N1/362 ,  H01F5/02 ,  H01F2005/025 ,  Y10T29/49002 ,  Y10T29/49071

    摘要： In accordance with an embodiment, an implantable lead assembly is provided comprised of an elongated body including a distal end, a proximal end having a header connector portion for coupling the elongated body with an implantable medical device, and an intermediate segment located between the distal and proximal ends. An intermediate electrode is disposed at the intermediate segment along the elongated body. A conductor is disposed in the elongated body and electrically coupled with the header connector portion and the intermediate electrode. The conductor wound within the intermediate segment to form first and second inductive coils that are axially separated from each other by an inter-coil gap, wherein the first and second inductive coils have different self-resonant frequencies.

    摘要翻译： 根据一个实施例，提供一种可植入引线组件，其包括细长主体，其包括远端，近端具有用于将细长主体与可植入医疗装置连接的插头连接器部分，以及位于远端和 近端 中间电极沿着细长体设置在中间部分。 导体设置在细长主体中并与插头连接器部分和中间电极电耦合。 导体缠绕在中间段内以形成通过线圈间隙彼此轴向分离的第一和第二感应线圈，其中第一和第二感应线圈具有不同的自谐振频率。

    SYSTEMS AND METHODS FOR DETERMINING INDUCTANCE AND CAPACITANCE VALUES FOR USE WITH LC FILTERS WITHIN IMPLANTABLE MEDICAL DEVICE LEADS TO REDUCE LEAD HEATING DURING MRI
    9.
    发明申请
    SYSTEMS AND METHODS FOR DETERMINING INDUCTANCE AND CAPACITANCE VALUES FOR USE WITH LC FILTERS WITHIN IMPLANTABLE MEDICAL DEVICE LEADS TO REDUCE LEAD HEATING DURING MRI 有权
    用于确定电导率和电容值的系统和方法，用于在可植入医疗器械中使用LC过滤器，在MRI期间减少引线加热

    公开(公告)号：US20130123876A1

    公开(公告)日：2013-05-16

    申请号：US11955268

    申请日：2007-12-12

    申请人： Xiaoyi Min

    发明人： Xiaoyi Min

    IPC分类号： A61N1/375

    CPC分类号： A61N1/056 ,  A61N1/086 ,  A61N1/3718 ,  G01R33/3685

    摘要： Techniques are provided for configuring filters for reducing heating within pacing/sensing leads of a pacemaker or implantable cardioverter-defibrillator that might occur due to induced currents during a magnetic resonance imaging (MRI) procedure or in the presence of other sources of strong radio frequency (RF) fields. In particular, techniques are provided for selecting inductors and capacitors for use in LC filters while taking into account the tolerances of the component devices, as well as the target impedance of the components and the particular RF frequencies to be filtered.

    摘要翻译： 提供了用于配置用于减少起搏器或植入式心律转复除颤器的起搏/感测引线内的加热的技术，其可能由于在磁共振成像（MRI）程序期间的感应电流或其它强射频源的存在而发生 RF）字段。 特别地，提供了用于选择用于LC滤波器的电感器和电容器的技术，同时考虑到组件装置的公差以及组件的目标阻抗和要滤波的特定RF频率。