公开(公告)号：US20130122611A1

公开(公告)日：2013-05-16

申请号：US13669113

申请日：2012-11-05

申请人： YAO-HUNG YANG ,  Abhijit Kangude ,  Sanjeev Baluja ,  Michael Martinelli ,  Liliya Krivulina ,  Thomas Nowak ,  Juan Carlos Rocha-Alvarez ,  Scott A. Hendrickson

发明人： YAO-HUNG YANG ,  Abhijit Kangude ,  Sanjeev Baluja ,  Michael Martinelli ,  Liliya Krivulina ,  Thomas Nowak ,  Juan Carlos Rocha-Alvarez ,  Scott A. Hendrickson

IPC分类号： H05B37/02 ,  H01L21/26 ,  H01L21/66

CPC分类号： H05B41/3921 ,  H01L21/67115 ,  H05B41/3922

摘要： The present invention generally relates to methods of controlling UV lamp output to increase irradiance uniformity. The methods generally include determining a baseline irradiance within a chamber, determining the relative irradiance on a substrate corresponding to a first lamp and a second lamp, and determining correction or compensation factors based on the relative irradiances and the baseline irradiance. The lamps are then adjusted via closed loop control using the correction or compensation factors to individually adjust the lamps to the desired output. The lamps may optionally be adjusted to equal irradiances prior to adjusting the lamps to the desired output. The closed loop control ensures process uniformity from substrate to substrate. The irradiance measurement and the correction or compensation factors allow for adjustment of lamp set points due to chamber component degradation, chamber component replacement, or chamber cleaning.

摘要翻译： 本发明一般涉及控制UV灯输出以增加辐照度均匀性的方法。 方法通常包括确定室内的基线辐照度，确定对应于第一灯和第二灯的衬底上的相对辐照度，以及基于相对辐照度和基线辐照度确定校正或补偿因子。 然后通过使用校正或补偿因子的闭环控制来调节灯，以将灯单独调节到期望的输出。 在将灯调节到期望的输出之前，灯可以可选地被调整为相等的辐照度。 闭环控制确保从基板到基板的工艺均匀性。 辐照度测量和校正或补偿因素允许由于室部件劣化，腔室部件更换或腔室清洁而调节灯具设定点。

公开(公告)号：US20120129275A1

公开(公告)日：2012-05-24

申请号：US13011687

申请日：2011-01-21

申请人： Yao-Hung Yang ,  Abhijit Kangude ,  Sanjeev Baluja ,  Michael Martinelli ,  Liliya Krivulina ,  Thomas Nowak ,  Juan Carlos Rocha-Alvarez ,  Scott Hendrickson

发明人： Yao-Hung Yang ,  Abhijit Kangude ,  Sanjeev Baluja ,  Michael Martinelli ,  Liliya Krivulina ,  Thomas Nowak ,  Juan Carlos Rocha-Alvarez ,  Scott Hendrickson

IPC分类号： H01L21/26 ,  H05B37/02

CPC分类号： H05B41/3921 ,  H01L21/67115 ,  H05B41/3922

摘要： The present invention generally relates to methods of controlling UV lamp output to increase irradiance uniformity. The methods generally include determining a baseline irradiance within a chamber, determining the relative irradiance on a substrate corresponding to a first lamp and a second lamp, and determining correction or compensation factors based on the relative irradiances and the baseline irradiance. The lamps are then adjusted via closed loop control using the correction or compensation factors to individually adjust the lamps to the desired output. The lamps may optionally be adjusted to equal irradiances prior to adjusting the lamps to the desired output. The closed loop control ensures process uniformity from substrate to substrate. The irradiance measurement and the correction or compensation factors allow for adjustment of lamp set points due to chamber component degradation, chamber component replacement, or chamber cleaning.

摘要翻译： 本发明一般涉及控制UV灯输出以增加辐照度均匀性的方法。 方法通常包括确定室内的基线辐照度，确定对应于第一灯和第二灯的衬底上的相对辐照度，以及基于相对辐照度和基线辐照度确定校正或补偿因子。 然后通过使用校正或补偿因子的闭环控制来调节灯，以将灯单独调节到期望的输出。 在将灯调节到期望的输出之前，灯可以可选地被调整为相等的辐照度。 闭环控制确保从基板到基板的工艺均匀性。 辐照度测量和校正或补偿因素允许由于室部件劣化，腔室部件更换或腔室清洁而调节灯具设定点。

公开(公告)号：US08309421B2

公开(公告)日：2012-11-13

申请号：US13011687

申请日：2011-01-21

申请人： Yao-Hung Yang ,  Abhijit Kangude ,  Sanjeev Baluja ,  Michael Martinelli ,  Liliya Krivulina ,  Thomas Nowak ,  Juan Carlos Rocha-Alvarez ,  Scott Hendrickson

发明人： Yao-Hung Yang ,  Abhijit Kangude ,  Sanjeev Baluja ,  Michael Martinelli ,  Liliya Krivulina ,  Thomas Nowak ,  Juan Carlos Rocha-Alvarez ,  Scott Hendrickson

IPC分类号： H01L21/336 ,  H01L21/76

CPC分类号： H05B41/3921 ,  H01L21/67115 ,  H05B41/3922

摘要： The present invention generally relates to methods of controlling UV lamp output to increase irradiance uniformity. The methods generally include determining a baseline irradiance within a chamber, determining the relative irradiance on a substrate corresponding to a first lamp and a second lamp, and determining correction or compensation factors based on the relative irradiances and the baseline irradiance. The lamps are then adjusted via closed loop control using the correction or compensation factors to individually adjust the lamps to the desired output. The lamps may optionally be adjusted to equal irradiances prior to adjusting the lamps to the desired output. The closed loop control ensures process uniformity from substrate to substrate. The irradiance measurement and the correction or compensation factors allow for adjustment of lamp set points due to chamber component degradation, chamber component replacement, or chamber cleaning.

摘要翻译： 本发明一般涉及控制UV灯输出以增加辐照度均匀性的方法。 方法通常包括确定室内的基线辐照度，确定对应于第一灯和第二灯的衬底上的相对辐照度，以及基于相对辐照度和基线辐照度确定校正或补偿因子。 然后通过使用校正或补偿因子的闭环控制来调节灯，以将灯单独调节到期望的输出。 在将灯调节到期望的输出之前，灯可以可选地被调整为相等的辐照度。 闭环控制确保从基板到基板的工艺均匀性。 辐照度测量和校正或补偿因素允许由于室部件劣化，腔室部件更换或腔室清洁而调节灯具设定点。

公开(公告)号：US20110160463A1

公开(公告)日：2011-06-30

申请号：US12999961

申请日：2009-06-16

申请人： George A. Moniz ,  Matthew J. Frizzle ,  Charles Bernard ,  Michael Martinelli ,  Margaret Faul ,  Jay Larrow ,  Karl B. Hansen ,  Liane Klingensmith

发明人： George A. Moniz ,  Matthew J. Frizzle ,  Charles Bernard ,  Michael Martinelli ,  Margaret Faul ,  Jay Larrow ,  Karl B. Hansen ,  Liane Klingensmith

IPC分类号： C07D277/14

CPC分类号： C07D277/54 ,  C07D263/48 ,  C07D277/42

摘要： The present invention relates to methods of making compounds that inhibit 11-β-hydroxysteroid dehydrogenase type 1 enzyme (11-β HSD1). One method comprises (a) contacting a compound of formula (II) with a chiral base, deprotonating agent, and an alkylating agent R3-LG, (b) contacting the product of (a) with an acid to form a salt, and (c) reacting the salt with a base to form the compound of formula (I); wherein Z, R1, R2, and R3 are defined herein.

摘要翻译： 本发明涉及制备抑制11-＆bgr-羟基类固醇脱氢酶1型酶（11-和bgr; HSD1）的化合物的方法。 一种方法包括（a）使式（II）化合物与手性碱，去质子化剂和烷基化剂R3-LG接触，（b）使（a）的产物与酸形成盐，和 c）使所述盐与碱反应以形成式（I）化合物; 其中Z，R 1，R 2和R 3在本文中定义。

公开(公告)号：US20050075344A1

公开(公告)日：2005-04-07

申请号：US10500476

申请日：2003-01-21

申请人： Ryan Backer ,  Ivan Collado Caño ,  Oscar De Furtos-Garcia ,  Christopher Doecke ,  Matthew Fisher ,  Steven Kuklish ,  Vincent Mancuso ,  Michael Martinelli ,  Jeffrey Mullaney ,  Paul Ornstein ,  Chaoyu Xie

发明人： Ryan Backer ,  Ivan Collado Caño ,  Oscar De Furtos-Garcia ,  Christopher Doecke ,  Matthew Fisher ,  Steven Kuklish ,  Vincent Mancuso ,  Michael Martinelli ,  Jeffrey Mullaney ,  Paul Ornstein ,  Chaoyu Xie

IPC分类号： A61K31/496 ,  A61K45/00 ,  A61P3/04 ,  A61P3/10 ,  A61P15/08 ,  A61P15/10 ,  A61P43/00 ,  C07B53/00 ,  C07B61/00 ,  C07C67/343 ,  C07C69/73 ,  C07C69/734 ,  C07D209/44 ,  C07D211/26 ,  C07D211/96 ,  C07D217/26 ,  C07D295/02 ,  C07D295/033 ,  C07D309/04 ,  C07D335/02 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  A61K31/495 ,  C07D43/02 ,  C07D49/02

CPC分类号： C07D217/26 ,  C07D209/44 ,  C07D211/26 ,  C07D211/96 ,  C07D295/033 ,  C07D309/04 ,  C07D335/02 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12

摘要： The present invention relates to melanocortin receptor agonist of the formula (I): which is useful in the treatment for obesity, diabetes, and male and/or female sexual dysfunction.

摘要翻译： 本发明涉及式（I）的黑皮质素受体激动剂：其可用于治疗肥胖症，糖尿病和男性和/或女性性功能障碍。

公开(公告)号：US20100280255A1

公开(公告)日：2010-11-04

申请号：US12665405

申请日：2008-06-20

申请人： George A. Moniz ,  Matthew J. Frizzle ,  Charles Bernard ,  Michael Martinelli ,  Margaret Faul ,  Roger Nani ,  Jay Larrow

发明人： George A. Moniz ,  Matthew J. Frizzle ,  Charles Bernard ,  Michael Martinelli ,  Margaret Faul ,  Roger Nani ,  Jay Larrow

IPC分类号： C07D277/54

CPC分类号： C07D277/42

摘要： The present invention relates to methods of making compounds that inhibit 11-hydroxysteroid dehydrogenase type 1 enzyme (11-HSD1). One method comprises (a) contacting a compound of formula (II) sequentially with a chiral base in the presence of an amine, and an alkylating agent R3-LG, (b) contacting the product of (a) with an acid to form a salt, and (c) reacting the salt with a base to form the compound of formula (I), wherein Z, R1, R2, and R3 are defined herein.

摘要翻译： 本发明涉及制备抑制11-羟类固醇脱氢酶1型酶（11-HSD1）的化合物的方法。 一种方法包括（a）在胺的存在下将式（II）的化合物与手性碱相接触，和烷基化试剂R3-LG，（b）使（a）的产物与酸反应形成 盐，和（c）使该盐与碱反应以形成式（I）化合物，其中Z，R 1，R 2和R 3在本文中定义。

公开(公告)号：US20060036189A1

公开(公告)日：2006-02-16

申请号：US11247848

申请日：2005-10-11

申请人： Michael Martinelli ,  Mark Hunter ,  Sheri McCoid ,  Paul Kessman

发明人： Michael Martinelli ,  Mark Hunter ,  Sheri McCoid ,  Paul Kessman

IPC分类号： A61B5/103 ,  A61B19/00

CPC分类号： A61B34/20 ,  A61B90/39 ,  A61B2017/00477 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/3916 ,  A61B2090/397 ,  A61B2090/3983 ,  A61B2090/3987

摘要： An integrated surgical anchor/localization sensor is disclosed. The anchor is adapted to be secured to an anatomical structure and contains a sensor housing. A receiver is located within the sensor housing and is adapted to sense reference signals generated by a surgical guidance system. A transmitter, connected to the receiver, conveys to a processor signals received by the receiver, so that the signals transmitted by the receiver are indicative of a current position of the anchor. Various other structures and methods are also disclosed.

公开(公告)号：US08536345B2

公开(公告)日：2013-09-17

申请号：US12999961

申请日：2009-06-16

申请人： George A. Moniz ,  Matthew J. Frizzle ,  Charles Bernard ,  Michael Martinelli ,  Margaret Faul ,  Jay Larrow ,  Karl B. Hansen ,  Liane Klingensmith

发明人： George A. Moniz ,  Matthew J. Frizzle ,  Charles Bernard ,  Michael Martinelli ,  Margaret Faul ,  Jay Larrow ,  Karl B. Hansen ,  Liane Klingensmith

IPC分类号： C07D277/54

CPC分类号： C07D277/54 ,  C07D263/48 ,  C07D277/42

摘要： The present invention relates to methods of making compounds that inhibit 11-β-hydroxysteroid dehydrogenase type 1 enzyme (11-β HSD1). One method comprises (a) contacting a compound of formula (II) with a chiral base, deprotonating agent, and an alkylating agent R3-LG, (b) contacting the product of (a) with an acid to form a salt, and (c) reacting the salt with a base to form the compound of formula (I); wherein Z, R1, R2, and R3 are defined herein.

摘要翻译： 本发明涉及制备抑制11-β-羟基类固醇脱氢酶1型酶（11-βHSD1）的化合物的方法。 一种方法包括（a）使式（II）化合物与手性碱，去质子化剂和烷基化剂R3-LG接触，（b）使（a）的产物与酸形成盐，和 c）使所述盐与碱反应以形成式（I）化合物; 其中Z，R 1，R 2和R 3在本文中定义。

公开(公告)号：US20060235299A1

公开(公告)日：2006-10-19

申请号：US11400996

申请日：2006-04-10

申请人： Michael Martinelli

发明人： Michael Martinelli

IPC分类号： A61M25/00

CPC分类号： A61B8/4461 ,  A61B8/12 ,  A61B8/445 ,  G10K11/357

摘要： A method and apparatus for intravascular imaging utilizes a rotating magnetic field generated outside of the patient's body to cause a substantially synchronous rotation of an ultrasonic signal inside the patient's body.

摘要翻译： 用于血管内成像的方法和装置利用在患者身体外部产生的旋转磁场使得超声信号在患者体内的基本上同步的旋转。

公开(公告)号：US10535022B1

公开(公告)日：2020-01-14

申请号：US13548089

申请日：2012-07-12

申请人： Alastair Hood ,  Michael Martinelli

发明人： Alastair Hood ,  Michael Martinelli

IPC分类号： G06Q10/06 ,  G06Q30/02

摘要： A sustainable business development management system and method are provided for businesses which provides these businesses with a comprehensive understanding of their sustainability goals, projects, and metrics including the environmental and societal impacts of their business with the ability to manage and report on these parameters in a way that makes sense for their business.