摘要:
The present invention provides a neurodegenerative disease therapeutic agent containing as its active ingredient a (15R)-isocarbacycline derivative indicated by the following formula [I] or a 15-deoxy-isocarbacycline derivative indicated by the following formula [III]: (wherein, R1 represents a C1-C6 alkylene group, and R2 represents a hydrogen atom, a C1-C7, alkyl group or protective group); or, (wherein, R1 and R2 are the same as those defined in formula [I]).
摘要:
The present invention provides an apoptosis inhibitor containing a 15R-isocarbacyclin derivative or a 15-deoxy-isocarbacyclin derivative, which can be manufactured easily and economically by means of chemical synthesis.
摘要:
A receptor (binding protein) specific for 6(R)-L-erythro-5,6,7,8-tetrahydrobiopterin which is a drug effective for neuropsychiatric disorders such as infantile autism is provided. This receptor is contained in the cytosol fraction or the membrane fraction obtained from a homogenate of an animal organ. It is solubilized from the membrane fraction in the presence of 3-{(3-cholamidopropyl)-dimethylammonio}-1-propanesulfonate (CHAPS). This receptor is characterized in that the binding ability thereof to 6R-BH4 is mostly lost by heating at 100.degree. C. for 10 minutes, the binding ability thereof to 6R-BH4 is significantly lost by incubating with trypsin at 37.degree. C. for 15 minutes, and said receptor shows a relative molecular weight of about 340 to 380 kilodaltons when specifically bound to tritium-labeled 6R-BH4 and analyzed with a molecular sieve provided with a COSMOSIL 5 Diol-300 column.
摘要:
An acyloxylation catalyst is obtained by loading (a) a first component containing at least one element of Groups 8, 9, 10 and 11 of the Periodic Table, (b) a second component containing an element which is at least one element of Groups 8, 9, 10 and 11 of the Periodic Table and which is different from the element of the first component, and (c) a third component containing an element which is a component that produces a precipitation-starting pH below the precipitation-starting pH of the first component and second component and which is different from the elements of the first component and second component, onto (d) a support. A catalyst is obtained that can be used to efficiently carry out acyloxylation for economical production of acyloxylated compounds.
摘要:
A facsimile system with the body thereof usable as a subunit of a cordless telephone is disclosed. A parent unit is connected to the telephone line. A facsimile subunit is connected by radio to the parent unit. A telephone subunit is also connected by radio to the parent unit. A circuit included in the parent unit detects a signal indicating that the other party is in facsimile transmission mode. When a call signal is detected from the telephone line, the parent unit connects the line. When a CNG signal is detected, on the other hand, the parent unit connects the facsimile subunit by radio. In the case where a CNG signal is not detected, the parent unit starts the ring-up tone on the telephone subunit. An AGC circuit and a voice mute circuit are included in the parent unit.
摘要:
An optical deflector device including a substrate having a thermo-optic effect, a two-dimensional optical waveguide formed on a surface of the substrate, for guiding a light beam therethrough, so as to trap the light beam in a direction of thickness of the substrate, and a device for producing a temperature gradient in the two-dimensional optical waveguide in a direction which is parallel to a plane of the substrate and which intersects the direction of propagation of the light beam through the optical waveguide. Also disclosed is an optical deflector device including a solid deflector element for deflecting a light beam, and an incident-angle changing device for progressively changing an angle of incidence of the light beam upon the solid deflector element. The incident-angle changing device includes a plurality of optical waveguides which are arranged so as to guide the light beam to the solid deflector element. The angle of incidence of the light beam upon the solid deflector element differs depending upon the optical waveguides through which the light beam is selectively guided to the solid deflector element.
摘要:
Duplicate optical fibers connect between a base station controller and a radio base station for each route. The duplicate optical fiber is connected to each of the radio base stations for each route through a star coupler. The radio base stations are arranged in each of areas so that the radio base stations for different routes are arranged adjacent to each other.
摘要:
This invention provides a method wherein a protein sparingly soluble in water, or a protein in a hardly extractable state, is detected sharply and easily in subsequent immunoreaction while high efficiency of extraction from a sample is maintained. Disclosed is a highly sensitive and easy immunoassay characterized in that a water-sparingly-soluble protein in a sample, or a protein in a hardly extractable state, is extracted/solubilized with an aqueous solvent containing an ionic surfactant at relatively high concentration, and then the protein in the extract is detected directly by an antibody raised against the protein previously denatured with the ionic surfactant.
摘要:
A facsimile apparatus which utilizes a dialing signal of a tone signal and can be used as a called-side communication apparatus to print desired character string information through a simple operation of a calling-side telephone set, and also a facsimile communication method in the facsimile apparatus. In the called-side facsimile apparatus, a character string information memory stores therein a plurality of character string information and unique numbers associated therewith; whereas a character information memory stores therein image information corresponding to the respective character string information. When a user of the calling-side communication apparatus enters a number corresponding to desired character string information, this causes a dialing signal indicative of the number to be transmitted to the facsimile apparatus. In the facsimile apparatus, a control unit converts to image information the character string information corresponding to the number indicated by the dialing signal detected by a dialing signal detector, and the converted image information is printed by a printer.
摘要:
Duplicate optical fibers connect between a base station controller and a radio base station for each route. The duplicate optical fiber is connected to each of the radio base stations for each route through a star coupler. The radio base stations are arranged in each of areas so that the radio base stations for different routes are arranged adjacent to each other.