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1.发明授权Phosphate, liposome comprising the phosphate as membrane constituent, and cosmetic and liposome preparation comprising the liposome 失效磷酸盐，包含磷酸盐作为膜组织的脂质体，以及包含脂质体的化妆和脂质体制备
公开(公告)号：US5153000A
公开(公告)日：1992-10-06
申请号：US437099
申请日：1989-11-16
申请人： Yoshiko Chikawa , Katsumi Kita , Mitsuharu Masuda , Tomihiro Kurosaki , Takashi Itoh , Noriko Inoue , Haruya Kato , Takashi Imamura , Yasuo Ishii , Yoshitaka Kokusho , Akira Tsunoda , Shigeaki Kato
发明人： Yoshiko Chikawa , Katsumi Kita , Mitsuharu Masuda , Tomihiro Kurosaki , Takashi Itoh , Noriko Inoue , Haruya Kato , Takashi Imamura , Yasuo Ishii , Yoshitaka Kokusho , Akira Tsunoda , Shigeaki Kato
CPC分类号： C07H11/04 , A61K8/14 , A61K8/556 , A61K9/1271 , A61K9/1272 , A61Q19/00 , C07F9/10 , Y10S977/797 , Y10S977/904 , Y10S977/915 , Y10S977/926
摘要： A novel monophosphate and a novel diphosphate prepared by a phosphatidyl transfer reaction of a phospholipid and an alcohol in the presence of phospholipase D are disclosed. The phosphates can independently or together form small and stable liposomes which can include active components therein. Cosmetic compositions comprising these phosphates or liposomes penetrate well into the hair and the skin, and exhibit long-lasting excellent moisture-retaining, beauty, skin-activation effects.
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2.发明授权Metal salts of monoalkyl phosphates, preparation thereof, and cosmetic compositions comprising same 失效磷酸单烷基酯的金属盐，其制备方法和包含它们的化妆品组合物
公开(公告)号：US4804533A
公开(公告)日：1989-02-14
申请号：US44198
申请日：1987-04-30
摘要： Metal salts of monoalkyl phosphates of the following formula ##STR1## in which each R represents a saturated or unsaturated, linear or branched hydrocarbon group having from 8 to 32 carbon atoms, and M represents an alkaline earth metal or divalent transition metal.The metal salts are particularly suitable as cosmetic powders, fillers for resins, and lubricants, parting agents and pigment dispersants for polymeric compounds. When used as cosmetic powders, the metal salts improve spreadability, moistness, smoothness, adherence, transparency and covering power of cosmetics.Preparation process of the metal salts is also disclosed.
摘要翻译： 其中每个R表示具有8至32个碳原子的饱和或不饱和的直链或支链烃基，并且M表示碱土金属或二价过渡金属，其具有下式的单烷基磷酸盐金属盐。 金属盐特别适合用作化妆粉，树脂用填料，润滑剂，脱模剂和高分子化合物的颜料分散剂。 当用作化妆品粉末时，金属盐提高化妆品的铺展性，润湿性，光滑度，粘附性，透明度和覆盖力。 还公开了金属盐的制备方法。
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公开(公告)号：US5196186A
公开(公告)日：1993-03-23
申请号：US815225
申请日：1991-12-31
摘要： An alkali metal monoalkylphosphate having a saturated or unsaturated straight-chain or branched hydrocarbon group having from 8 to 32 carbon atoms is described; also described is a process for preparing particles of said alkali metal zinc monoalkylphosphate and cosmetics containing said particles.
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4.发明授权Alkali metal zinc monoalkylphosphate, particles thereof, process for preparing the same, and cosmetic containing the same 失效碱金属锌一烷基磷酸盐，其颗粒，其制备方法以及含有它们的化妆品
公开(公告)号：US5176904A
公开(公告)日：1993-01-05
申请号：US693496
申请日：1991-04-30
摘要： An alkali metal monoalkylphosphate having a saturated or unsaturated straight-chain or branched hydrocarbon group having from 8 to 32 carbon atoms is described; also described is a process for preparing particles of said alkali metal zinc monoalkylphosphate and cosmetics containing said particles.
摘要翻译： 描述具有8至32个碳原子的饱和或不饱和直链或支链烃基的碱金属单烷基磷酸酯; 还描述了制备所述碱金属锌单烷基磷酸盐的颗粒和含有所述颗粒的化妆品的方法。
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5.发明授权Alkali metal zinc monoalkylphosphate, particles thereof, process for preparing the same, and cosmetic containing the same 失效碱金属锌化合物单烷基磷酸酯，其颗粒，其制备方法和包含其的化妆品
公开(公告)号：US5174991A
公开(公告)日：1992-12-29
申请号：US494001
申请日：1990-02-27
摘要： An alkali metal monoalkylphosphate having a saturated or unsaturated straight-chain or branched hydrocarbon group having from 8 to 32 carbon atoms is described; also described is a process for preparing particles of said alkali metal zinc monoalkylphosphate and cosmetics containing said particles.
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公开(公告)号：US4994581A
公开(公告)日：1991-02-19
申请号：US452419
申请日：1989-12-19
CPC分类号： C07F9/65502 , C07F9/10
摘要： A novel phosphoric ester of the formula (I) ##STR1## wherein, Z represents the following radicals ##STR2## useful as modifiers for amino acids, peptides and proteins which are easily decomposable in living bodies.
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7.发明授权
公开(公告)号：US5071585A
公开(公告)日：1991-12-10
申请号：US604172
申请日：1990-10-29
IPC分类号： A61K8/06 , A61K8/00 , A61K8/55 , A61K8/58 , A61Q5/02 , A61Q19/10 , C07F9/09 , C08G65/32 , C11D1/78 , C11D1/88 , C11D3/36
摘要： Phosphoric acid esters represented by the following formulae (I) and (IX) as well as processes for preparing them are disclosed. ##STR1## wherein R.sub.1 represents a linear or branched, alkyl or alkenyl group having a C.sub.1-36 carbon atom content, with or without the hydrogen atom(s) being substituted with fluorine atom(s), or a phenyl group with substituted linear or branched alkyl group(s) having a C.sub.1-15 carbon atom content, R.sub.2 represents an alkylene group having a C.sub.2-3 carbon atom content, R.sub.3 and R.sub.4 independently denote a hydrogen atom or an alkyl group having a C.sub.1-3 carbon atom content, R.sub.5 and R.sub.6 independently denote a hydrogen atom, or an alkyl, alkenyl, or phenyl group with or without the hydrogen atom(s) being substituted with group(s) containing hetero atom(s), excepting for a mercapto group, R.sub.7 and R.sub.8 independently denote a hydrogen atom, or an alkyl, or alkenyl group, m is an integer of 0-30, n is an integer of 0-5, l is an integer of 0-3, M is a hydrogen atom, an alkali metal, an alkali earth metal, an ammonium group, an alkyl amine group, or an alkanol amine group. The phosphoric acid esters have outstanding surface activity and good foaming capability, and imparts only extremely low irritation to the skin. The detergent composition into which they are formulated is particularly useful as, shampoo, baby shampoo, body shampoo.
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8.发明授权Modification method for peptides and proteins by reacting with a phosphoric acid ester 失效通过与磷酸酯反应来改变肽和蛋白质的方法
公开(公告)号：US5043424A
公开(公告)日：1991-08-27
申请号：US260709
申请日：1988-10-21
IPC分类号： C07K14/655 , C07K1/00 , C07K1/02 , C07K1/107 , C07K1/113 , C07K1/14 , C07K4/00 , C07K5/06 , C07K14/00 , C07K14/575 , C07K14/76 , C07K16/00 , C12N9/16 , C12N9/96
CPC分类号： C07K5/06191 , C07K1/1077
摘要： A peptide or protein is modified by reacting a phosphoric acid ester represented by the following general formula (I) with a peptide or protein: ##STR1## wherein R.sub.1 means a linear or branched, C.sub.1-36 alkyl or C.sub.2-36 alkenyl group whose hydrogen atom or atoms may be substituted by the corresponding number of fluorine atom(s) or a phenyl group substituted by at least one linear or branched C.sub.1-15 alkyl group, R.sub.2 denotes a C.sub.2-3 alkylene group, m stands for a number of 0-30, and M is a hydrogen atom, an alkali metal ion, an alkaline earth metal ion, an ammonium ion, an alkylamine residue or an alkanolamine residue.
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公开(公告)号：US4787940A
公开(公告)日：1988-11-29
申请号：US12496
申请日：1987-02-09
摘要： A novel method for purifying a sugar phosphate or its salt, in which a sugar-containing mixture of a sugar phosphate or its salt and phosphoric acid or its salt is subjected to electrodialysis to remove the phosphoric acid or its salt from the mixture.According to this method, the phosphoric acid or its salt can be readily obtained in a reusable form. The method is thus quite advantageous in view of the economy.
摘要翻译： 一种纯化糖磷酸盐或其盐的新方法，其中糖磷酸盐或其盐的含糖混合物和磷酸或其盐进行电渗析以从混合物中除去磷酸或其盐。 根据该方法，可以容易地以可重复使用的形式获得磷酸或其盐。 鉴于经济，该方法是非常有利的。
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10.发明授权
公开(公告)号：US4985412A
公开(公告)日：1991-01-15
申请号：US260868
申请日：1988-10-21
IPC分类号： A61K8/06 , A61K8/00 , A61K8/55 , A61K8/58 , A61Q5/02 , A61Q19/10 , C07F9/09 , C08G65/32 , C11D1/78 , C11D1/88 , C11D3/36
摘要： Phosphoric acid esters represented by the following formulae (I) and (IX) as well as processes for preparing them are disclosed. ##STR1## wherein R.sub.1 represents a linear or branched, alkyl or alkenyl group having a C.sub.1-36 carbon atom content, with or without the hydrogen atom(s) being substituted with fluorine atom(s), or a phenyl group with substituted linear or branched alkyl group(s) having a C.sub.1-15 carbon atom content, R.sub.2 represents an alkylene group having a C.sub.2-3 carbon atom content, R.sub.3 and R.sub.4 independently denote a hydrogen atom or an alkyl group having a C.sub.1-3 carbon atom content, R.sub.5 and R.sub.6 independently denote a hydrogen atom, or an alkyl, alkenyl, or phenyl group with or without the hydrogen atom(s) being substituted with group(s) containing hetero atom(s), excepting for a mercapto group, R.sub.7 and R.sub.8 independently denote a hydrogen atom, or an alkyl, or alkenyl group, m is an integer of 0-30, n is an integer of 0-5, l is an integer of 0-3, M is a hydrogen atom, an alkali metal, an alkali earth metal, on ammonium group, an alkyl amine group, or an alkanol amine group. The phosphoric acid ester have outstanding surface activity and good foaming capability, and imparts only extremely low irritation to the skin. The detergent composition into which they are formulated is particularly useful as, shampoo, baby shampoo, body shampoo.
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