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公开(公告)号：US07304315B2
公开(公告)日：2007-12-04
申请号：US11404248
申请日：2006-04-13
申请人： Yoshinori Iketaki , Masaaki Fujii , Takeshi Watanabe , Takashige Omatsu , Kimihisa Yamamoto , Toshio Suzuki
发明人： Yoshinori Iketaki , Masaaki Fujii , Takeshi Watanabe , Takashige Omatsu , Kimihisa Yamamoto , Toshio Suzuki
CPC分类号： G01N21/6458 , G01N21/645 , G01N2021/6419
摘要： A three-dimensional analyzing device includes a first beam source for generating a first beam, a second beam source for generating a second beam, an optical system for spatially overlapping the first and second beams at least partly and irradiating the beams onto a specimen to three-dimensionally confine a photoactive region in a specimen, and a photo acceptance element for accepting a response light emitted from the photoactive region. Preferably, the device further includes an operation unit for calculating a correlation function of a response light in the time domain based on the output of the photo acceptance element to analyze a desired physical value of the specimen.
摘要翻译： 三维分析装置包括用于产生第一光束的第一光束源，用于产生第二光束的第二光束源，至少部分地将第一和第二光束空间重叠的光学系统，并将光束照射到样品上至三 视觉上将光活性区域限制在样本中，以及用于接受从光活性区域发射的响应光的光接收元件。 优选地，所述装置还包括操作单元，用于基于所述光接收元件的输出来计算所述时域中的响应光的相关函数，以分析所述样本的期望物理值。
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公开(公告)号：US20060290924A1
公开(公告)日：2006-12-28
申请号：US11404248
申请日：2006-04-13
申请人： Yoshinori Iketaki , Masaaki Fujii , Takeshi Watanabe , Takashige Omatsu , Kimihisa Yamamoto , Toshio Suzuki
发明人： Yoshinori Iketaki , Masaaki Fujii , Takeshi Watanabe , Takashige Omatsu , Kimihisa Yamamoto , Toshio Suzuki
IPC分类号： G01J3/00
CPC分类号： G01N21/6458 , G01N21/645 , G01N2021/6419
摘要： A three-dimensional analyzing device includes a first beam source for generating a first beam, a second beam source for generating a second beam, an optical system for spatially overlapping the first and second beams at least partly and irradiating the beams onto a specimen to three-dimensionally confine a photoactive region in a specimen, and a photo acceptance element for accepting a response light emitted from the photoactive region. Preferably, the device further includes an operation unit for calculating a correlation function of a response light in the time domain based on the output of the photo acceptance element to analyze a desired physical value of the specimen.
摘要翻译： 三维分析装置包括用于产生第一光束的第一光束源，用于产生第二光束的第二光束源，用于至少部分地将第一和第二光束空间重叠的光学系统，并将光束照射到样品上至三 视觉上将光活性区域限制在样本中，以及用于接受从光活性区域发射的响应光的光接收元件。 优选地，所述装置还包括操作单元，用于基于所述光接收元件的输出来计算所述时域中的响应光的相关函数，以分析所述样本的期望物理值。
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公开(公告)号：US06859313B2
公开(公告)日：2005-02-22
申请号：US10103190
申请日：2002-03-21
CPC分类号： G02B21/06
摘要： A microscope includes a first light source to emit a first light to excite a molecule of a sample to a higher energy level vibration state which belongs to a lowest energy level electron state from the ground state, a second light source to emit a second light source to excite the molecule to a higher energy level quantum state from the higher energy vibration state, an optical system to overlap the first light and the second light partially on the sample, and an optical detector to detect a given fluorescence from the irradiated region of the first light and the second light on the sample.
摘要翻译： 显微镜包括：第一光源，用于发射第一光以将样品的分子激发到属于基本状态的最低能量级电子态的较高能级振动状态，第二光源发射第二光源 从更高的能量振动状态激发分子到更高的能量级量子态，光学系统将部分地与样品上的第一光和第二光重叠，以及光学检测器，用于检测来自辐射源的照射区域的给定荧光 样品上的第一个光和第二个光。
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公开(公告)号：US07095556B2
公开(公告)日：2006-08-22
申请号：US10771729
申请日：2004-02-04
CPC分类号： G02B26/08
摘要： A microscope capable of being shaped into a beam with complete hollow shape by removing the disorder of the wavefront to the erase light, particularly, and capable of improving the spatial resolution by inducing a super-resolution near the limit, is provided. In the microscope, wherein a first light to excite a molecule from a ground-state to first electron excited state or a second light to excite the molecule from the first electron excited state to the second electron excited state with higher energy level, for a sample 56 including the molecule with three electronic states including at least a ground-state, are spatial phase-modulated into the prescribed beam shape, and parts of these first light and the second light are overlapped and focused to detect luminescence from the sample 56, a wavefront compensation means 61 is provided in the optical path of the first light and/or in the optical path of the second light, and the wavefront aberration caused in the first light and/or in the second light, is removed by the wavefront compensation means 61.
摘要翻译： 提供了能够通过将擦除光的波阵面除去特别是并且能够通过在接近极限附近引起超分辨率来改善空间分辨率而将具有完全中空形状的光束成形为显微镜的显微镜。 在显微镜中，其中将分子从基态激发到第一电子激发态的第一光或第二光以将分子从第一电子激发态激发至具有较高能级的第二电子激发态，对于样品 包括具有至少包括基态的三种电子状态的分子被空间相位调制成规定的波束形状，并且这些第一光和第二光的一部分被重叠和聚焦以检测来自样品56的发光， 波前补偿装置61设置在第一光的光路和/或第二光的光路中，并且在第一光和/或第二光中引起的波前像差被波前补偿装置除去 61。
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公开(公告)号：US06667830B1
公开(公告)日：2003-12-23
申请号：US09445389
申请日：2000-03-17
IPC分类号： G02B2100
CPC分类号： G01N21/6458 , G01N21/636 , G01N21/64 , G01N21/6428 , G01N21/6445 , G02B21/0032 , G02B21/0056 , G02B21/0072 , G02B21/0076 , G02B21/16 , G21K7/00
摘要： A microscope system comprising an adjusted specimen and a microscope body, wherein the adjusted specimen is dyed with molecule which has three electronic states including at least a ground state and in which an excited wavelength band from the first electron excited state to the second electron excited state overlaps a fluorescent wavelength band upon deexcitation through a fluorescence process from the first electron excited state to a vibrational level in the ground state. There is provided a novel microscope system which is enabled to condense an erase light for exciting a molecule in the first electron excited state to the second electron excited state in an excellent beam profile by using a simple, compact optical system and which has high stability and operability and an excellent super-resolution.
摘要翻译： 一种显微镜系统，包括经调整的样本和显微镜主体，其中所述经调整的样本用分子染色，所述分子具有至少包括基态的三种电子状态，并且其中从第一电子激发态到第二电子激发态的激发波长带 通过从第一电子激发状态到基态的振动电平的荧光过程在激发下与荧光波长带重叠。 提供了一种新颖的显微镜系统，其能够通过使用简单紧凑的光学系统来将用于将第一电子激发态的分子激发到第二电子激发态的擦除光以优异的光束轮廓冷凝，并且具有高稳定性和 可操作性和出色的超分辨率。
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公开(公告)号：US20070291353A1
公开(公告)日：2007-12-20
申请号：US11659525
申请日：2005-07-25
CPC分类号： G01N21/6458 , G01N2021/6419 , G01N2021/6439 , G02B21/002 , G02B21/16 , G02B27/58
摘要： [Task] To provide a super-resolution microscope whereby the light source of pump light and erase light can be selected easily and a super-resolution can be reliably achieved through a simple and inexpensive arrangement. [Solution of the Task] A super-resolution microscope includes an optical system (3, 4, 9) for combining a part of a first coherent light from a first light source (2) and a part of a second coherent light from a second light source (1) and focusing the coherent lights onto a sample (10), scanning means (6, 7) for scanning the coherent lights, and detecting means (16) for detecting an optical response signal from the sample (10). The microscope is configured so as to satisfy the following conditions: σ01Ipτ≦1, and 0.65(λe/λp)≦τσdipIe where λp is the wavelength of the first coherent light, λe is the wavelength of the second coherent light, τ is the excited lifetime in which the molecule is excited by the first coherent light from the ground state to the first electron-excited state, Ip is the maximum photon flux on the sample surface of the first coherent light, Ie is the maximum photon flux on the sample surface of the second coherent light, σ01, is the absorption cross-sectional area when the molecule is exited from the ground state to the first electron-excited state, and σdip is the fluorescence suppression cross-sectional area.
摘要翻译： [任务]提供一种能够容易地选择泵浦光和擦除光的光源的超分辨率显微镜，并且通过简单且廉价的布置可以可靠地实现超分辨率。 [任务的解决方案]超分辨率显微镜包括用于组合来自第一光源（2）的第一相干光的一部分和来自第二光源的第二相干光的一部分的光学系统（3,4,9） 光源（1），并将相干光聚焦到样品（10）上，用于扫描相干光的扫描装置（6,7）以及用于检测来自样品（10）的光响应信号的检测装置（16）。 显微镜被配置为满足以下条件：<？in-line-formula description =“In-line Formulas”end =“lead”？> sigma Iptau <= 1， ？in-line-formula description =“In-line Formulas”end =“tail”？> <？in-line-formula description =“In-line formula”end =“lead”？> 0.65（lambdae / lambdap） = tausigma Ie <？in-line-formula description =“In-line Formulas”end =“tail”？>其中lambdap是第一个相干光的波长，lambdae是 第二相干光，tau是分子被从基态到第一电子激发态的第一相干光激发的激发寿命，Ip是第一相干光的样品表面上的最大光子通量，Ie是 第二相干光的样品表面上的最大光子通量σσ是当分子从基态退出到第一电子激发态时的吸收横截面积，而西格玛 浸渍 是荧光抑制截面积。
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公开(公告)号：US07551350B2
公开(公告)日：2009-06-23
申请号：US11659525
申请日：2005-07-25
CPC分类号： G01N21/6458 , G01N2021/6419 , G01N2021/6439 , G02B21/002 , G02B21/16 , G02B27/58
摘要： A super-resolution microscope includes an optical system for combining a part of a first coherent light from a first light source and a part of a second coherent light from a second light source and focusing the coherent lights onto a sample, scanning , unit for scanning the coherent lights, and a detecting unit for detecting an optical response signal from the sample. The microscope is configured so as to satisfy the following conditions: σ01Ipτ≦1, and 0.65(λe/λp)≦τσdipIe.
摘要翻译： 超分辨率显微镜包括用于组合来自第一光源的第一相干光的一部分和来自第二光源的第二相干光的一部分的光学系统，并将相干光聚焦到样本上，扫描单元进行扫描 相干光，以及用于检测来自样品的光响应信号的检测单元。 显微镜配置为满足以下条件：<？in-line-formula description =“In-line Formulas”end =“lead”？> sigma01Iptau <= 1，<？in-line-formula description =“ 在线公式“end =”tail“？> <？in-line-formula description =”In-line Formulas“end =”lead“？> 0.65（lambdae / lambdap）<= tausigmadipIe。 <？in-line-formula description =“In-line Formulas”end =“tail”？>
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公开(公告)号：US5835262A
公开(公告)日：1998-11-10
申请号：US580196
申请日：1995-12-28
申请人： Yoshinori Iketaki , Masaaki Fujii
发明人： Yoshinori Iketaki , Masaaki Fujii
CPC分类号： G02B21/06
摘要： A high-accuracy multi-wavelength optical microscope for providing a satisfactory contrast of image and much information about a sample. The microscope includes a plurality of light sources, a wavelength varietor independently varying the wavelength of the individual light sources, and polarization plane rotators on the optical path for each light source.
摘要翻译： 一种高精度多波长光学显微镜，用于提供令人满意的图像对比度和关于样品的大量信息。 显微镜包括多个光源，独立地改变各个光源的波长的波长变换器和用于每个光源的光路上的偏振面旋转器。
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9.发明授权公开(公告)号：US08457220B2
公开(公告)日：2013-06-04
申请号：US11830991
申请日：2007-07-31
申请人： Jung-hoon Suh , Masaaki Fujii , Sung-jin Kim , Ho-jin Kim
发明人： Jung-hoon Suh , Masaaki Fujii , Sung-jin Kim , Ho-jin Kim
IPC分类号： H04L27/28
CPC分类号： H04B7/0619 , H04B7/0617 , H04L25/03006 , H04L27/2626 , H04L27/2647 , H04L2025/03426
摘要： A multi-input multi-output orthogonal frequency division multiplexing (MIMO-OFDM) transceiving system is provided, in which an MIMO-OFDM receiver feeds back ordering information, such as the order of power intensities of reception signals of a plurality of reception antennas, to an MIMO-OFDM transmitter. The MIMO-OFDM transmitter arranges subcarriers, to which data symbols have been allocated, so that the subcarriers respectively correspond to a plurality of transmission antennas, according to the fed-back information. Thus, a specific substream can be transmitted via a transmission antenna having the greatest channel gain. Consequently, the probability of properly recovering the specific substream is greatly increased.
摘要翻译： 提供一种多输入多输出正交频分复用（MIMO-OFDM）收发系统，其中MIMO-OFDM接收机反馈诸如多个接收天线的接收信号的功率强度的顺序的排序信息， 涉及MIMO-OFDM发射机。 根据反馈信息，MIMO-OFDM发射机布置已经分配了数据符号的子载波，使得子载波分别对应于多个发送天线。 因此，可以经由具有最大信道增益的发送天线来发送特定子流。 因此，适当恢复特定子流的概率大大增加。
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10.发明授权Radio transmission apparatus and method, radio reception apparatus and method, transmitting and receiving method, and recording medium 失效无线发送装置和方法，无线电接收装置和方法，发送和接收方法以及记录介质公开(公告)号：US07936740B2
公开(公告)日：2011-05-03
申请号：US11356149
申请日：2006-02-17
申请人： Masaaki Fujii
发明人： Masaaki Fujii
CPC分类号： H04L1/0631 , H04B7/0678 , H04L1/0625 , H04L5/026
摘要： Provided are a radio transmission apparatus and method, a radio receiving apparatus and method, a transmitting and receiving method, and a recording medium for use in a mobile communication system according to an Orthogonal Frequency Division Multiplexing-Code Division Multiplexing (OFDM-CDM)-based transmission diversity method. The radio transmitter codes transmission data into a plurality of time-space codes, generates spread signals by respectively mapping a plurality of spread codes and the time-space codes, and transmits the spread signals via a plurality of transmission antennae, each of the spread codes containing a combination of codes whose signs are alternately equal and opposite in units of specific spreading lengths. Accordingly, it is possible to transmit data without a feedback of control information from a radio receiver.
摘要翻译： 提供了根据正交频分复用码分多址（OFDM-CDM）的移动通信系统中使用的无线发送装置和方法，无线接收装置和方法，发送和接收方法以及记录介质， 基于传输的分集方法。 无线电发射机将传输数据编码成多个时空码，通过分别映射多个扩展码和时间空间码产生扩展信号，并经由多个发射天线发射扩展信号，每个扩展码 包含符号交替相等并且以特定扩展长度为单位的代码的组合。 因此，可以从无线电接收机发送没有控制信息的反馈的数据。
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