公开(公告)号：US4393134A

公开(公告)日：1983-07-12

申请号：US424096

申请日：1982-09-27

申请人： Akira Yano ,  Yoshitada Saito ,  Yasushi Kasahara

发明人： Akira Yano ,  Yoshitada Saito ,  Yasushi Kasahara

IPC分类号： C12Q1/00 ,  G01N33/68 ,  G01N33/96

CPC分类号： G01N33/6812 ,  Y10S435/805 ,  Y10S435/839

摘要： A standard blood filter paper for use in diagnosis of histidinemia, comprising a piece of filter paper, and a blood material infiltrated in the above filter paper containing a known concentration of histidine and at least one salt selected from the group consisting of a dithionite, a disulfite and a bisulfite. The standard blood filter paper can be preserved for a long term at -20.degree. C.

摘要翻译： 一种用于诊断组氨酸血症的标准血液滤纸，包括一张滤纸，以及浸入上述滤纸中的含有已知浓度的组氨酸和至少一种选自连二亚硫酸盐， 亚硫酸氢盐和亚硫酸氢盐。 标准血液滤纸可长期保存在-20℃。

公开(公告)号：US4367286A

公开(公告)日：1983-01-04

申请号：US300753

申请日：1981-09-10

申请人： Yoshitada Saito ,  Akira Yano ,  Yasushi Kasahara

发明人： Yoshitada Saito ,  Akira Yano ,  Yasushi Kasahara

IPC分类号： G01N33/60 ,  G01N33/68 ,  G01N33/96 ,  C12Q1/00

CPC分类号： G01N33/6815 ,  G01N33/96 ,  Y10S435/805 ,  Y10S435/839

摘要： A reference blood filter paper for measuring the concentration of methionine in the blood, comprising a piece of blood filter paper, a blood material infiltered in the blood filter paper containing a known concentration of methionine and at least one water-soluble, sulfur-containing antioxidant represented by general formula: ##STR1## where n=1 or 2.

摘要翻译： 一种用于测量血液中甲硫氨酸浓度的参考血液滤纸，包括一片血液滤纸，渗透在含有已知浓度的甲硫氨酸和至少一种水溶性含硫抗氧化剂的血液滤纸中的血液物质 由通式表示：其中n = 1或2。

公开(公告)号：US08034353B2

公开(公告)日：2011-10-11

申请号：US12280535

申请日：2007-02-16

申请人： Akira Yano ,  Toshiki Nishizawa ,  Yoshikatsu Miwa

发明人： Akira Yano ,  Toshiki Nishizawa ,  Yoshikatsu Miwa

IPC分类号： A61K39/02 ,  A61K39/04 ,  A61K39/05 ,  A61K39/08 ,  C07H21/04

CPC分类号： A61K39/0008 ,  A61K2039/543 ,  A61K2039/55516 ,  A61K2039/55544 ,  A61K2039/6037 ,  C07K14/005 ,  C07K14/4711 ,  C07K2319/00 ,  C12N2740/16222

摘要： An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid β-peptide, such as Alzheimer's disease. The present invention solves the above object by providing a peptide vaccine constructed by inserting a peptide having an amino acid sequence of a cell attachment motif of a cell adhesive molecule to a peptide which consists of a peptide having an amino acid sequence of multiagretope type T-cell epitope, which has been generated immunological memory, or a peptide including the same; an linker peptide; and a peptide having an amino acid sequence of a B cell epitope which is a specific region of amyloid β-peptide or a peptide including the same.

摘要翻译： 本发明的目的是提供一种用于预防和/或治疗由淀粉样蛋白和诸如阿尔茨海默氏病等引起的疾病的肽疫苗。 本发明通过提供通过将具有细胞粘附分子的细胞附着基序的氨基酸序列的肽插入到由具有多重靶向型T-氨基酸的氨基酸序列的肽组成的肽而构成的肽疫苗来解决上述目的， 已经产生免疫记忆的细胞表位或包含其的肽; 接头肽; 以及具有B细胞表位的氨基酸序列的肽，所述B细胞表位是淀粉样蛋白的特异性区域或包含该氨基酸的肽。

公开(公告)号：US20050048321A1

公开(公告)日：2005-03-03

申请号：US10930755

申请日：2004-09-01

申请人： Enji Fujita ,  Hideaki Yamanaka ,  Tsuyoshi Onuma ,  Satoshi Matsunuma ,  Akira Yano ,  Tetsunori Koda ,  Katsusuke Shimazaki

发明人： Enji Fujita ,  Hideaki Yamanaka ,  Tsuyoshi Onuma ,  Satoshi Matsunuma ,  Akira Yano ,  Tetsunori Koda ,  Katsusuke Shimazaki

IPC分类号： G11B5/64 ,  G11B5/66 ,  G11B5/667

CPC分类号： G11B5/66 ,  G11B5/656 ,  G11B5/667 ,  G11B5/732 ,  G11B5/7325

摘要： A magnetic recording medium based on the perpendicular magnetic recording system includes a substrate; a back layer which is formed on the substrate and which is formed of a soft magnetic material; an in-plane magnetized layer which is formed on the back layer and which has in-plane magnetization; and a recording layer which is formed on the in-plane magnetized layer and which has perpendicular magnetization, wherein the in-plane magnetized layer has a coercivity in an in-plane direction larger than a magnetic field generated by residual magnetization in a perpendicular direction of the recording layer. The influence on the reproduction output, caused by the mirror image effect of the soft magnetic back layer is reduced in wide range recording densities, thereby improving the resolution by decreasing the difference between the reproduction outputs of the magnetic recording medium at the low recording density and at the high recording density.

摘要翻译： 基于垂直磁记录系统的磁记录介质包括基板; 背衬层，其形成在所述基板上并且由软磁性材料形成; 面内磁化层，其形成在背层上并具有面内磁化; 以及形成在所述面内磁化层上并且具有垂直磁化的记录层，其中所述面内磁化层的面内方向的矫顽力大于在垂直方向上的残余磁化产生的磁场的矫顽力 录音层。 在宽范围的记录密度下，由软磁背层的镜像效果引起的对再现输出的影响减小，从而通过将低记录密度的磁记录介质的再现输出与 在高记录密度。

公开(公告)号：US08722119B2

公开(公告)日：2014-05-13

申请号：US12064971

申请日：2006-08-29

申请人： Hiroshi Horiuchi ,  Akira Yano

发明人： Hiroshi Horiuchi ,  Akira Yano

IPC分类号： A23C9/12

CPC分类号： A23C9/12 ,  A23C9/123 ,  A23C9/1307 ,  A23C2240/20 ,  A23V2002/00 ,  A23V2250/124

摘要： The present invention relates to a process for producing fermented milk, including adding to a milk mix a starter in an amount of from 0.2 to 0.8% by weight with respect to the total amount of the milk mix, reducing the dissolved oxygen concentration in said mix to 5 ppm or less and conducting a fermentation after said addition of the starter and said reduction of the dissolved oxygen concentration

摘要翻译： 本发明涉及一种生产发酵乳的方法，包括向母乳混合物中加入相对于母乳混合物总量为0.2至0.8重量％的起始物，降低所述混合物中的溶解氧浓度 至5ppm以下，并且在加入起始物之后进行发酵，并降低溶解氧浓度

公开(公告)号：US07348077B2

公开(公告)日：2008-03-25

申请号：US10930755

申请日：2004-09-01

申请人： Enji Fujita ,  Hideaki Yamanaka ,  Tsuyoshi Onuma ,  Satoshi Matsunuma ,  Akira Yano ,  Tetsunori Koda ,  Katsusuke Shimazaki

发明人： Enji Fujita ,  Hideaki Yamanaka ,  Tsuyoshi Onuma ,  Satoshi Matsunuma ,  Akira Yano ,  Tetsunori Koda ,  Katsusuke Shimazaki

IPC分类号： G11B5/66 ,  G11B5/70

CPC分类号： G11B5/66 ,  G11B5/656 ,  G11B5/667 ,  G11B5/732 ,  G11B5/7325

摘要： A magnetic recording medium based on the perpendicular magnetic recording system includes a substrate; a back layer which is formed on the substrate and which is formed of a soft magnetic material; an in-plane magnetized layer which is formed on the back layer and which has in-plane magnetization; and a recording layer which is formed on the in-plane magnetized layer and which has perpendicular magnetization, wherein the in-plane magnetized layer has a coercivity in an in-plane direction larger than a magnetic field generated by residual magnetization in a perpendicular direction of the recording layer. The influence on the reproduction output, caused by the mirror image effect of the soft magnetic back layer is reduced in wide range recording densities, thereby improving the resolution by decreasing the difference between the reproduction outputs of the magnetic recording medium at the low recording density and at the high recording density.

摘要翻译： 基于垂直磁记录系统的磁记录介质包括基板; 背衬层，其形成在所述基板上并且由软磁性材料形成; 面内磁化层，其形成在背层上并具有面内磁化; 以及形成在所述面内磁化层上并且具有垂直磁化的记录层，其中所述面内磁化层的面内方向的矫顽力大于在垂直方向上的残余磁化产生的磁场的矫顽力 录音层。 在宽范围的记录密度下，由软磁背层的镜像效果引起的对再现输出的影响减小，从而通过将低记录密度的磁记录介质的再现输出与 在高记录密度。

公开(公告)号：US06846582B2

公开(公告)日：2005-01-25

申请号：US10292469

申请日：2002-11-13

申请人： Tsuyoshi Onuma ,  Akira Yano ,  Satoshi Matsunuma ,  Takanobu Takayama

发明人： Tsuyoshi Onuma ,  Akira Yano ,  Satoshi Matsunuma ,  Takanobu Takayama

IPC分类号： G11B5/64 ,  G11B5/65 ,  G11B5/667 ,  G11B5/673 ,  G11B5/73 ,  G11B5/66 ,  B32B15/01 ,  C25D5/26 ,  G11B5/70

CPC分类号： G11B5/732 ,  G11B5/656 ,  G11B5/667 ,  G11B5/7325 ,  Y10S428/90 ,  Y10T428/12861 ,  Y10T428/12875 ,  Y10T428/24942 ,  Y10T428/265

摘要： A magnetic recording medium 100 comprises, on a substrate 1, a soft magnetic layer 3, a seed layer 5, and a recording layer 6 having an artificial lattice structure. The seed layer 5 is formed of Pd and one selected from the group consisting of Si, B, C, and Zr. Accordingly, the magnetic exchange coupling force of the recording layer 6 in the in-plane direction can be weakened. Minute recording magnetic domains can be formed in the recording layer 6, and the magnetization transition area is distinct as well. Thus, the medium noise is reduced. That is, reproduction can be performed with a low medium noise even when information is recorded at a high density. A magnetic storage apparatus, which is provided with the magnetic recording medium as described above, can achieve an areal recording density of 150 Gigabits/square inch.

摘要翻译： 磁记录介质100在基板1上包括软磁层3，种子层5和具有人造晶格结构的记录层6。 种子层5由Pd和选自由Si，B，C和Zr组成的组中的一种形成。 因此，可以削弱记录层6在面内方向上的磁交换耦合力。 可以在记录层6中形成分钟记录磁畴，并且磁化过渡区也是不同的。 因此，中等噪声降低。 也就是说，即使以高密度记录信息，也可以以低的中等噪声进行再现。 如上所述设置有磁记录介质的磁存储装置可以实现150吉比特/平方英寸的面密度记录密度。

公开(公告)号：US06815098B2

公开(公告)日：2004-11-09

申请号：US10411299

申请日：2003-04-11

申请人： Satoshi Matsunuma ,  Akira Yano ,  Tsuyoshi Onuma ,  Takanobu Takayama ,  Harumi Hieida ,  Kouichirou Wakabayashi

发明人： Satoshi Matsunuma ,  Akira Yano ,  Tsuyoshi Onuma ,  Takanobu Takayama ,  Harumi Hieida ,  Kouichirou Wakabayashi

IPC分类号： G11B566

CPC分类号： G11B5/00 ,  G11B5/012 ,  G11B5/66 ,  G11B5/74 ,  G11B5/851 ,  Y10S428/90 ,  Y10T428/12465 ,  Y10T428/12868 ,  Y10T428/265

摘要： A magnetic recording medium comprises, on a substrate, a soft magnetic layer, a first seed layer, a second seed layer, and a recording layer having an artificial lattice structure. The first seed layer contains oxide of Fe. The second seed layer contains one of Pd and Pt, Si, and N. The magnetic exchange coupling force in the in-plane direction of the recording layer is weakened by the first seed layer and the second seed layer. Accordingly, minute recording magnetic domains can be formed in the recording layer, and the magnetization transition area is distinct as well. Even when information is recorded at a high density, the information can be reproduced with low noise. A magnetic storage apparatus, which is provided with such a magnetic recording medium, makes it possible to achieve an areal recording density of 150 gigabits/square inch.

摘要翻译： 磁记录介质在基板上包括软磁层，第一晶种层，第二晶种层和具有人造晶格结构的记录层。 第一种子层含有Fe的氧化物。 第二种子层包含Pd和Pt，Si和N中的一个。记录层的面内方向上的磁交换耦合力被第一种子层和第二种子层削弱。 因此，可以在记录层中形成分钟记录磁畴，并且磁化过渡区也是不同的。 即使当以高密度记录信息时，可以以低噪声再现信息。 具有这种磁记录介质的磁存储装置使得可以实现150吉比特/平方英寸的面积记录密度。

公开(公告)号：US06699602B2

公开(公告)日：2004-03-02

申请号：US10084944

申请日：2002-03-01

申请人： Mitsutoshi Honda ,  Hiroki Yamamoto ,  Takashi Naito ,  Tatsumi Hirano ,  Tetsuo Nakazawa ,  Fumiyoshi Kirino ,  Teruaki Takeuchi ,  Akira Yano ,  Nobuyuki Inaba ,  Satoshi Matsunuma

发明人： Mitsutoshi Honda ,  Hiroki Yamamoto ,  Takashi Naito ,  Tatsumi Hirano ,  Tetsuo Nakazawa ,  Fumiyoshi Kirino ,  Teruaki Takeuchi ,  Akira Yano ,  Nobuyuki Inaba ,  Satoshi Matsunuma

IPC分类号： G11B566

CPC分类号： G11B5/7325 ,  G11B5/72 ,  G11B5/8404 ,  G11B5/8408 ,  Y10S428/90 ,  Y10T428/12465 ,  Y10T428/12618

摘要： An amorphous magnetic recording medium comprising a substrate and an amorphous magnetic layer, where a magnetic domain formation-controlling layer comprising a main phase and 1 to 3 kinds of discrete spherical isolating phases arranged horizontally in lines in the main phase or 1 to 3 kinds of discrete spherical phases vertically stacked one upon another in the main phase is formed on the top side or the bottom side directly or through at least one of other layers to bring the amorphous magnetic layer into a finer magnetic domain structure, can satisfy high density recording.

摘要翻译： 一种非晶磁记录介质，包括基板和非晶磁性层，其中包括主相的磁畴形成控制层和主相中的水平排列的1至3种离散的球形隔离相或1至3种 在主相中垂直层叠的离散球相直接或通过其它层中的至少一个形成在顶侧或底侧，以使非晶磁性层进入更细的磁畴结构，可以满足高密度记录。

公开(公告)号：US20070118784A1

公开(公告)日：2007-05-24

申请号：US11555524

申请日：2006-11-01

申请人： Massahiro Fusumada ,  Hitoshi Saitoh ,  Shinji Togashi ,  Akira Yano

发明人： Massahiro Fusumada ,  Hitoshi Saitoh ,  Shinji Togashi ,  Akira Yano

IPC分类号： G01R31/28

CPC分类号： G01R31/31725 ,  G01R31/3187

摘要： A semiconductor integrated circuit that self-tests the skew margin of the clock and data signals in an LVDS. A clock signal CKB1 is held in flip-flop circuit 105 synchronously with checking clock signal A1. Checking pattern signal PAT_A is held in flip-flop circuit 104 synchronously with checking clock signal A2. When the skew margin of clock signal CKA_IN and data signal DA_IN are checked, the checking signal TCKA of flip-flop circuit 105 is input instead of clock signal CKA_IN, and the checking signal TDA of flip-flop circuit 104 is input instead of clock signal DA_IN. The timing relationship between clock signal CKB7 and checking timing signal A1 and the timing relationship between clock signal CKB7 and checking timing signal A2 are controlled independently by timing control circuit 109.

摘要翻译： 一种半导体集成电路，可以自我测试LVDS中时钟和数据信号的偏移余量。 时钟信号CKB 1与检查时钟信号A 1同步地保持在触发器电路105中。 检查模式信号PAT_A与检查时钟信号A 2同步地保持在触发器电路104中。 当检查时钟信号CKA_IN和数据信号DA_IN的偏斜边缘时，输入触发器电路105的检查信号TCKA而不是时钟信号CKA_IN，并且输入触发器电路104的检查信号TDA而不是时钟信号 DA_IN。 定时控制电路109独立地控制时钟信号CKB 7与检查定时信号A 1之间的时序关系以及时钟信号CKB 7与检查定时信号A2之间的时序关系。