专利检索 ap:("Yuehua He" OR "Aniko Takacs-Cox" OR "Anthony BOey" OR "Brent` Zaluski" OR "Roger A. Smith" OR "Audrey A. Deschamps" OR "Rui Avelar") AND inv:"Aniko Takacs-Cox" 第 1 页

1.

发明申请
BIOCOMPATIBLE CROSSLINKED HYDROGELS, DRUG-LOADED HYDROGELS AND METHODS OF USING THE SAME 有权
标题翻译：可生物降解的交联氢化物，药物加载水凝胶及其使用方法

公开(公告)号：US20090324720A1

公开(公告)日：2009-12-31

申请号：US12428411

申请日：2009-04-22

申请人： Yuehua He , Aniko Takacs-Cox , Anthony Boey , Brent Zaluski , Roger A. Smith , Audrey A. Deschamps , Rui Avelar

发明人： Yuehua He , Aniko Takacs-Cox , Anthony Boey , Brent Zaluski , Roger A. Smith , Audrey A. Deschamps , Rui Avelar

IPC分类号： A61K9/10 , A61K38/20 , A61K38/48 , A61K38/16 , A61K31/445 , A61K31/4025 , A61K31/10 , A61K31/08 , C07D403/14 , C07C317/00 , C07C43/04

CPC分类号： A61L26/0019 , A61K9/0024 , A61K9/06 , A61K47/34 , A61L24/0015 , A61L24/0031 , A61L24/0042 , A61L26/0066 , A61L26/008 , A61L26/009 , A61L31/145 , A61L31/148 , A61L31/16 , A61L2300/00 , A61L2300/204 , A61L2300/402 , C07D403/14 , C08G65/00 , C08G65/3312 , C08G65/3324 , C08G65/33317 , C08G65/33337 , C08G65/33368 , C08G65/3342 , C08G65/337 , C08J3/075 , C08J2371/00 , C08L2203/02

摘要： Disclosed are hydrogel compositions formed by the mixture of a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more electrophilic groups, and a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more nucleophilic groups. Disclosed are also methods of preparing the above hydrogels. The hydrogel compositions can further comprise pharmaceuticals, such as analgesics or local anesthetics. Disclosed are also methods of sealing a wound, preventing post-surgical adhesion, and reducing post-surgical pain using the disclosed hydrogels.

摘要翻译： 公开了由一个被一个或多个聚乙二醇取代的四甲基甲烷的混合物形成的水凝胶组合物，其中每个聚乙二醇取代基独立地被一个或多个亲电基团进一步取代，和被一个或多个聚乙二醇取代的四甲基甲烷，聚乙二醇取代基独立地被一个或多个亲核基团进一步取代。还公开了制备上述水凝胶的方法。水凝胶组合物可以进一步包含药物，例如止痛剂或局部麻醉剂。还公开了使用所公开的水凝胶密封伤口，防止手术后粘连和减少手术后疼痛的方法。

2.

发明申请
BIOCOMPATIBLE CROSSLINKED HYDROGELS, DRUG-LOADED HYDROGELS AND METHODS OF USING THE SAME 审中-公开

公开(公告)号：US20160228601A1

公开(公告)日：2016-08-11

申请号：US14838213

申请日：2015-08-27

申请人： Yuehua He , Aniko Takacs-Cox , Anthony BOey , Brent` Zaluski , Roger A. Smith , Audrey A. Deschamps , Rui Avelar

发明人： Yuehua He , Aniko Takacs-Cox , Anthony BOey , Brent` Zaluski , Roger A. Smith , Audrey A. Deschamps , Rui Avelar

IPC分类号： A61L26/00 , C08G65/00 , C08J3/075 , C07D403/14

CPC分类号： A61L26/0019 , A61K9/0024 , A61K9/06 , A61K47/34 , A61L24/0015 , A61L24/0031 , A61L24/0042 , A61L26/0066 , A61L26/008 , A61L26/009 , A61L31/145 , A61L31/148 , A61L31/16 , A61L2300/00 , A61L2300/204 , A61L2300/402 , C07D403/14 , C08G65/00 , C08G65/3312 , C08G65/3324 , C08G65/33317 , C08G65/33337 , C08G65/33368 , C08G65/3342 , C08G65/337 , C08J3/075 , C08J2371/00 , C08L2203/02

摘要： Disclosed are hydrogel compositions formed by the mixture of a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more electrophilic groups, and a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more nucleophilic groups. Disclosed are also methods of preparing the above hydrogels. The hydrogel compositions can further comprise pharmaceuticals, such as analgesics or local anesthetics. Disclosed are also methods of sealing a wound, preventing post-surgical adhesion, and reducing post-surgical pain using the disclosed hydrogels.

3.

发明授权
Biocompatible crosslinked hydrogels, drug-loaded hydrogels and methods of using the same 有权
标题翻译：生物相容性交联水凝胶，载药水凝胶及其使用方法

公开(公告)号：US09125814B2

公开(公告)日：2015-09-08

申请号：US12428411

申请日：2009-04-22

申请人： Yuehua He , Aniko Takacs-Cox , Anthony Boey , Brent Zaluski , Roger A. Smith , Audrey A. Deschamps , Rui Avelar

发明人： Yuehua He , Aniko Takacs-Cox , Anthony Boey , Brent Zaluski , Roger A. Smith , Audrey A. Deschamps , Rui Avelar

IPC分类号： A61K9/10 , A61K38/20 , A61K38/48 , A61K38/16 , A61K31/445 , A61K31/4025 , A61K31/10 , A61K31/08 , C07D403/14 , C07C317/00 , C07C43/04 , A61K9/06 , A61K9/00 , A61K47/34 , A61L24/00 , A61L26/00 , A61L31/14 , A61L31/16 , C08G65/331 , C08G65/332 , C08G65/333 , C08G65/334 , C08G65/337

CPC分类号： A61L26/0019 , A61K9/0024 , A61K9/06 , A61K47/34 , A61L24/0015 , A61L24/0031 , A61L24/0042 , A61L26/0066 , A61L26/008 , A61L26/009 , A61L31/145 , A61L31/148 , A61L31/16 , A61L2300/00 , A61L2300/204 , A61L2300/402 , C07D403/14 , C08G65/00 , C08G65/3312 , C08G65/3324 , C08G65/33317 , C08G65/33337 , C08G65/33368 , C08G65/3342 , C08G65/337 , C08J3/075 , C08J2371/00 , C08L2203/02

摘要： Disclosed are hydrogel compositions formed by the mixture of a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more electrophilic groups, and a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more nucleophilic groups. Disclosed are also methods of preparing the above hydrogels. The hydrogel compositions can further comprise pharmaceuticals, such as analgesics or local anesthetics. Disclosed are also methods of sealing a wound, preventing post-surgical adhesion, and reducing post-surgical pain using the disclosed hydrogels.

摘要翻译： 公开了由一个被一个或多个聚乙二醇取代的四甲基甲烷的混合物形成的水凝胶组合物，其中每个聚乙二醇取代基独立地被一个或多个亲电基团进一步取代，和被一个或多个聚乙二醇取代的四甲基甲烷，聚乙二醇取代基独立地被一个或多个亲核基团进一步取代。还公开了制备上述水凝胶的方法。水凝胶组合物可以进一步包含药物，例如止痛剂或局部麻醉剂。还公开了使用所公开的水凝胶密封伤口，防止手术后粘连和减少手术后疼痛的方法。

4.

发明申请
Polymer compositions and methods for their use 审中-公开

公开(公告)号：US20050196421A1

公开(公告)日：2005-09-08

申请号：US11001417

申请日：2004-12-01

申请人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss

发明人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss

IPC分类号： A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05

CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432

摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.

5.

发明申请
Polymer compositions and methods for their use 审中-公开

公开(公告)号：US20050187140A1

公开(公告)日：2005-08-25

申请号：US11000408

申请日：2004-11-29

申请人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss

发明人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss

IPC分类号： A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05

CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432

摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.

6.

发明申请
POLYMER COMPOSITIONS AND METHODS FOR THEIR USE 审中-公开
标题翻译：聚合物组合物及其使用方法

公开(公告)号：US20120052040A1

公开(公告)日：2012-03-01

申请号：US13069258

申请日：2011-03-22

申请人： William L. Hunter , Philip M. Toleikis , David M. Gravelt , Arpita Maiti , Richard T. Liggins , Aniko Takacs-Cox , Rui Avelar , Troy A.E. Loss , Dechi Guan , Kaiyue Wang

发明人： William L. Hunter , Philip M. Toleikis , David M. Gravelt , Arpita Maiti , Richard T. Liggins , Aniko Takacs-Cox , Rui Avelar , Troy A.E. Loss , Dechi Guan , Kaiyue Wang

IPC分类号： A61K31/77 , A61K31/513 , A61K31/436 , A61P31/00 , C07D239/553 , C07D498/16 , C08G81/00 , A61P35/00 , A61K31/337 , C07D205/12

CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432

摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.

摘要翻译： 包含抗纤维化剂和/或聚合物组合物的组合物可用于各种医学应用，包括预防手术粘连，治疗炎性关节炎，治疗瘢痕和瘢痕疙瘩，治疗血管疾病和预防软骨失利。