摘要:
The present invention relates to amine derivatives represented by formula (1) or salts thereof. R3 represents C1-C3 alkyl, hydroxylated C1-C5 alkyl, C1-C5 acyl; C2-C5 alkenyl, or a halogen atom; and k, l, and m are each an integer of 1 to 4.) Exhibiting excellent antifungal effect, these compounds are highly useful as antifungal agents, antifungal compositions, drugs, etc.
摘要:
Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below and salts thereof are provided. [in the formula (1, R1 represents a C1-5 alkyl group which may be halogenated, R2 represents 4-(1,1-dimethylalkyl)benzyl group, 4-(1-methyl-phenylethyl)benzyl group, 1-or 2-naphthylmethyl group, or a hydrocarbon group having 3,3-dimethyl-1-butynyl group or a phenyl group at its terminal and 1 to 3 double bonds; R3 represents oxygen atom or a methylene group which may be substituted by a C1-4 alkyl group; and R4 represents 1-or 2 naphthyl group or a phenyl group which may be substituted.
摘要翻译:提供了具有下述通式(1)表示的优异的抗真菌作用的新型胺衍生物及其盐。[式1中,R1表示可被卤化的C1-5烷基,R2表示4-(1,1 - 二甲基烷基)苄基,4-(1-甲基 - 苯基乙基)苄基,1-或2-萘基甲基或其末端具有3,3-二甲基-1-丁炔基或苯基的烃基和1 至3个双键; R 3表示氧原子或可被C 1-4烷基取代的亚甲基; R 4表示1或2个萘基或可被取代的苯基。
摘要:
This invention relates to compounds represented by the following formula (1): ##STR1## wherein R.sup.1 represents a substituted or unsubstituted phenyl group, R.sup.2 represents a substituted or unsubstituted phenylene group, R.sup.3 represents a substituted or unsubstituted phenyl group or an aliphatic hydrocarbon group containing at least four .pi. electrons, R.sup.4 represents an alkyl group having 1 to 4 carbon atoms, and m and n individually represent integers of from 1 to 4, or salts thereof, and also to compositions containing the same. These compounds have antifungal activities and are useful as drugs.
摘要:
This invention relates to compounds represented by the following formula (1): ##STR1## wherein R.sup.1 represents a substituted or unsubstituted aromatic hydrocarbon group having 6 to 18 carbon atoms, R.sup.2 represents a hydrogen atom or a substituted or unsubstituted aromatic hydrocarbon group having 6 to 18 carbon atoms, R.sup.3 represents an alkyl group having 1 to 4 carbon atoms, R.sup.4 represents a substituted or unsubstituted phenyl group or an aliphatic hydrocarbon group containing at least four .pi. electrons, and m and n individually represent integers of from 1 to 4, or salts thereof, and also to compositions containing the same. These compounds have antifungal activities and are useful as drugs and the like.
摘要:
An information searching apparatus and method capable of producing good search results even in the case where specified search keywords are found separately on a plurality of documents. Upon receipt of a search request from a client, a first search process searches an index memory to find tentative search results. According to predetermined rules, it is determined to which group each tentative search result should belong. A second search process then searches documents at an upper hierarchical level in the same group, thus finding keyword hits in an upper-level document. A higher priority is then given to a group of documents in which the second search process has found keyword hits. Finally a list of locators is compiled and sent back to the requesting client to indicate the locations of relevant documents, where the locators are arranged in descending order of the display priority of corresponding groups.
摘要:
A water pump for cooling an engine in which an impeller accommodated in a pump housing provided on an engine body is mounted on an end of a rotational shaft rotatably supported on the pump housing for enhancing the reliability of the mounting strength of the impeller while avoiding an increase in cost. A fitting recess for fitting an end of the rotational shaft having an outer circumferential surface which is straight in an axial direction at least in a portion on the impeller side is provided in a central portion of the impeller. A bolt inserted into the central portion of the impeller is threaded in a coaxial direction with the end of the rotational shaft in a state that is fitted in the fitting recess.
摘要:
A dynamic image display device which reads out each frame from dynamic image data stored as successive frames every predetermined number of skipped frames, to display each of the frames at each predetermined display period on a window of a display device. The predetermined number of skipped frames and a display area size of the window are changeable. The dynamic image display device includes a display area size input device for inputting the display area size of the window, a storage device having a definition correlating the display area size with the predetermined number of skipped frames, a device for reading out from the storage device the predetermined number of skipped frames corresponding to the display area size of the window inputted by the display area size input device, and a device for displaying each of the frames on the window of the display device every read predetermined number of skipped frames.
摘要:
Disclosed herein is an antiprotozoal composition containing a 2-nitroimidazole derivative as its active component. This drug is especially useful against Trypanosoma cruzi. Process for the preparation is also disclosed.
摘要:
A novel heterocyclic derivative of formula (I): ##STR1## wherein R.sub.1 represents ##STR2## and R.sub.2 represents hydrogen or acyl. When R.sub.2 is acyl, the derivative can be prepared, for example, by the following process: ##STR3## wherein R.sub.4 is acyl and R.sub.1 is ##STR4## The derivative is less toxic and has radiosensitizing activity and antiviral activity even at a low concentration.Radiosensitizing agents and antiviral agents containing the derivative as active component are also disclosed.
摘要:
A method of preventing the atmosphere from entering a heat-insulating container adapted to temporarily reserve a low-temperature liquefied gas, wherein a dry gas is constantly supplied to the inside of the heat-insulating container when it is in an inoperative state, in order to maintain the inside of the heat-insulating container in a dry gas atmosphere having a pressure slightly higher than the atmospheric pressure. The dry gas is a vaporized gas of a low-temperature liquefied gas of the same kind as the low-temperature liquefied gas to be used. The dry gas is led out in the gas phase from a supply container for supplying the low-temperature liquefied gas to be used, or is a gas obtained by vaporizing a part of the low-temperature liquefied gas to be used, outside the supply container.