公开(公告)号：US20120150129A1

公开(公告)日：2012-06-14

申请号：US13210966

申请日：2011-08-16

申请人： Yun Jin ,  Yongxian Wu ,  Devesh Mathur

发明人： Yun Jin ,  Yongxian Wu ,  Devesh Mathur

IPC分类号： A61M5/34 ,  F16L25/00

CPC分类号： A61M39/10 ,  A61M2039/1094

摘要： Drug delivery devices having integrated non-luer connectors are described. An exemplary drug delivery device includes a container with a non-luer connector that prevents connection of a standard female luer connector to the container. One or more embodiments pertain to a container with a non-luer connector that prevents the formation of a fluid-tight seal between a standard female luer connector and the container. A non-luer connector for attachment to a container having a non-luer element is also described.

摘要翻译： 描述具有集成非路厄连接器的药物输送装置。 示例性药物递送装置包括具有非路厄连接器的容器，其防止标准母鲁尔连接器与容器的连接。 一个或多个实施例涉及具有非路厄连接器的容器，其防止在标准母路厄尔连接器和容器之间形成流体密封。 还描述了用于附接到具有非路厄元件的容器的非路厄连接器。

公开(公告)号：US09814870B2

公开(公告)日：2017-11-14

申请号：US13210966

申请日：2011-08-16

申请人： Yun Jin ,  Yongxian Wu ,  Devesh Mathur

发明人： Yun Jin ,  Yongxian Wu ,  Devesh Mathur

IPC分类号： A61M39/10

CPC分类号： A61M39/10 ,  A61M2039/1094

摘要： Drug delivery devices having integrated non-luer connectors are described. An exemplary drug delivery device includes a container with a non-luer connector that prevents connection of a standard female luer connector to the container. One or more embodiments pertain to a container with a non-luer connector that prevents the formation of a fluid-tight seal between a standard female luer connector and the container. A non-luer connector for attachment to a container having a non-luer element is also described.

公开(公告)号：US20110208160A1

公开(公告)日：2011-08-25

申请号：US12711805

申请日：2010-02-24

申请人： Yongxian Wu ,  Yun Jin ,  Mitali Aon

发明人： Yongxian Wu ,  Yun Jin ,  Mitali Aon

IPC分类号： A61M25/14

CPC分类号： A61M5/165 ,  A61M39/26 ,  A61M2005/1652

摘要： Drug delivery systems are provided that include an actuator assembly permanently attached to a filter for connection of a container containing medications such as epidural anesthesia, to a delivery site. In one or more embodiments, the actuator assembly includes a projection with an opening extending from a distal end of the actuator assembly in a proximal direction and the filter includes an inlet and an outlet in fluid communication with the opening. The filter includes a housing including two plates joined together or a cylindrical body defining a cavity containing filter materials. A conduit may be attached to the outlet of the filter to allow connection of the drug delivery systems described to a delivery site, such as a catheter. Methods of administering a medication to a delivery site are also provided.

摘要翻译： 提供了药物递送系统，其包括永久地附接到过滤器的致动器组件，用于将包含药物（例如硬膜外麻醉）的容器连接到递送部位。 在一个或多个实施例中，致动器组件包括具有从致动器组件的远端沿近端方向延伸的开口的突起，并且过滤器包括与开口流体连通的入口和出口。 过滤器包括壳体，其包括连接在一起的两个板或限定包含过滤材料的空腔的圆柱体。 导管可以连接到过滤器的出口，以允许所描述的药物递送系统连接到输送部位，例如导管。 还提供了将药物施用于递送部位的方法。

公开(公告)号：US20110208128A1

公开(公告)日：2011-08-25

申请号：US12711641

申请日：2010-02-24

申请人： Yongxian Wu ,  Yun Jin ,  Mitali Aon ,  Michael D. Garrison

发明人： Yongxian Wu ,  Yun Jin ,  Mitali Aon ,  Michael D. Garrison

IPC分类号： A61M25/14 ,  A61M25/16

CPC分类号： A61M39/24 ,  A61J1/201 ,  A61J1/2037 ,  A61J1/2051 ,  A61J1/2096 ,  A61M39/26 ,  A61M2039/248 ,  A61M2039/261

摘要： Drug delivery connectors are provided for permitting and blocking fluid flow between a container and a catheter connector or other drug delivery site. Embodiments of the drug delivery connectors include a ball valve for forming a releasable seal within the drug delivery connectors. In one or more embodiments, the ball valve prevents fluid flow between an open proximal end and an open distal end of the drug delivery connector and is movable in a proximal direction to release the releasable seal to permit fluid flow from the open proximal direction to the open distal direction. Methods of delivering medication to a catheter connector that includes an actuator are also provided

摘要翻译： 药物递送连接器用于允许和阻止容器和导管连接器或其它药物递送部位之间的流体流动。 药物递送连接器的实施例包括用于在药物输送连接器内形成可释放密封的球阀。 在一个或多个实施例中，球阀防止流体在药物输送连接器的开放的近端和敞开的远端之间流动，并且可以在近端方向上移动以释放可释放的密封，以允许流体从开口的近端方向流到 开放远端方向。 还提供了将药物递送到包括致动器的导管连接器的方法

公开(公告)号：US09205248B2

公开(公告)日：2015-12-08

申请号：US12711641

申请日：2010-02-24

申请人： Yongxian Wu ,  Yun Jin ,  Mitali Aon ,  Michael D. Garrison

发明人： Yongxian Wu ,  Yun Jin ,  Mitali Aon ,  Michael D. Garrison

IPC分类号： A61M5/00 ,  E03B1/00 ,  A61M39/24 ,  A61J1/20 ,  A61M39/26

CPC分类号： A61M39/24 ,  A61J1/201 ,  A61J1/2037 ,  A61J1/2051 ,  A61J1/2096 ,  A61M39/26 ,  A61M2039/248 ,  A61M2039/261

摘要： Drug delivery connectors are provided for permitting and blocking fluid flow between a container and a catheter connector or other drug delivery site. Embodiments of the drug delivery connectors include a ball valve for forming a releasable seal within the drug delivery connectors. In one or more embodiments, the ball valve prevents fluid flow between an open proximal end and an open distal end of the drug delivery connector and is movable in a proximal direction to release the releasable seal to permit fluid flow from the open proximal direction to the open distal direction. Methods of delivering medication to a catheter connector that includes an actuator are also provided.

摘要翻译： 药物递送连接器用于允许和阻止容器和导管连接器或其它药物递送部位之间的流体流动。 药物递送连接器的实施例包括用于在药物输送连接器内形成可释放密封的球阀。 在一个或多个实施例中，球阀防止流体在药物输送连接器的开放的近端和敞开的远端之间流动，并且可以在近端方向上移动以释放可释放的密封，以允许流体从开口的近端方向流到 开放远端方向。 还提供了将药物递送到包括致动器的导管连接器的方法。

公开(公告)号：US08465461B2

公开(公告)日：2013-06-18

申请号：US12844546

申请日：2010-07-27

申请人： Yongxian Wu ,  Yun Jin

发明人： Yongxian Wu ,  Yun Jin

IPC分类号： A61M5/00 ,  A61M37/00 ,  A61M5/14

CPC分类号： A61M5/34 ,  A61J1/2096 ,  A61M5/165 ,  A61M39/26 ,  A61M2039/1077 ,  A61M2039/1094 ,  A61M2205/273

摘要： Drug delivery devices having non-luer connections and adapters and adaption connectors for providing non-luer connections to drug delivery devices are provided. An exemplary drug delivery device for use with a catheter connection includes a blunt needle component with a non-luer connection and a filter component with a non-luer connection, wherein the non-luer connections of the blunt needle component and filter component are incompatible with standard luer fitting and intravenous route-accessing devices. In one or more embodiments, an adapter having a non-luer connection at one end and a luer connector is provided for use with blunt needle components and filter components wherein one of the blunt needle component and the filter component includes a luer connection and the other of the blunt needle component and the filter component includes a non-luer connection. Methods of delivering liquid medication to a catheter are also provided.

公开(公告)号：US09056163B2

公开(公告)日：2015-06-16

申请号：US12711805

申请日：2010-02-24

申请人： Yongxian Wu ,  Yun Jin ,  Mitali Aon

发明人： Yongxian Wu ,  Yun Jin ,  Mitali Aon

IPC分类号： A61M39/00 ,  A61M5/165 ,  A61M39/26

CPC分类号： A61M5/165 ,  A61M39/26 ,  A61M2005/1652

摘要： Drug delivery systems are provided that include an actuator assembly permanently attached to a filter for connection of a container containing medications such as epidural anesthesia, to a delivery site. In one or more embodiments, the actuator assembly includes a projection with an opening extending from a distal end of the actuator assembly in a proximal direction and the filter includes an inlet and an outlet in fluid communication with the opening. The filter includes a housing including two plates joined together or a cylindrical body defining a cavity containing filter materials. A conduit may be attached to the outlet of the filter to allow connection of the drug delivery systems described to a delivery site, such as a catheter. Methods of administering a medication to a delivery site are also provided.

摘要翻译： 提供了药物递送系统，其包括永久地附接到过滤器的致动器组件，用于将包含药物（例如硬膜外麻醉）的容器连接到递送部位。 在一个或多个实施例中，致动器组件包括具有从致动器组件的远端沿近端方向延伸的开口的突起，并且过滤器包括与开口流体连通的入口和出口。 过滤器包括壳体，其包括连接在一起的两个板或限定包含过滤材料的空腔的圆柱体。 导管可以连接到过滤器的出口，以允许所描述的药物递送系统连接到输送部位，例如导管。 还提供了将药物施用于递送部位的方法。

公开(公告)号：US20120029465A1

公开(公告)日：2012-02-02

申请号：US12844546

申请日：2010-07-27

申请人： Yongxian Wu ,  Yun Jin

发明人： Yongxian Wu ,  Yun Jin

IPC分类号： A61M25/00 ,  A61M39/10

CPC分类号： A61M5/34 ,  A61J1/2096 ,  A61M5/165 ,  A61M39/26 ,  A61M2039/1077 ,  A61M2039/1094 ,  A61M2205/273

摘要： Drug delivery devices having non-luer connections and adapters and adaption connectors for providing non-luer connections to drug delivery devices are provided. An exemplary drug delivery device for use with a catheter connection includes a blunt needle component with a non-luer connection and a filter component with a non-luer connection, wherein the non-luer connections of the blunt needle component and filter component are incompatible with standard luer fitting and intravenous route-accessing devices. In one or more embodiments, an adapter having a non-luer connection at one end and a luer connector is provided for use with blunt needle components and filter components wherein one of the blunt needle component and the filter component includes a luer connection and the other of the blunt needle component and the filter component includes a non-luer connection. Methods of delivering liquid medication to a catheter are also provided.

摘要翻译： 提供了具有非路厄尔连接和适配器的药物输送装置以及用于向药物输送装置提供非路厄尔连接的适配连接器。 与导管连接一起使用的示例性药物递送装置包括具有非路厄尔连接的钝针部件和具有非路厄尔连接的过滤器部件，其中钝针部件和过滤器部件的非路厄连接不兼容于 标准鲁尔接头和静脉插管设备。 在一个或多个实施例中，提供了在一端具有非路厄尔连接的适配器和鲁尔连接器，用于钝针部件和过滤器部件，其中钝针部件和过滤器部件中的一个包括鲁尔连接件，而另一个 钝针组件和过滤器部件包括非路厄尔连接。 还提供了将液体药物递送到导管的方法。

公开(公告)号：US20090032394A1

公开(公告)日：2009-02-05

申请号：US12161941

申请日：2007-01-23

申请人： Yongxian Wu ,  Yangyang Li

发明人： Yongxian Wu ,  Yangyang Li

IPC分类号： G01N27/30 ,  B05D5/12 ,  G01N27/28

CPC分类号： H01M4/8642 ,  C08J5/20 ,  F03G7/005 ,  H01B1/122

摘要： An embodiment provides an ionic polymer device comprising two extended electrode layers comprising a plurality of conductive particles, wherein the plurality of conductive particles form a concentration gradient in each of the two extended electrode layers, an ionic polymer dielectric layer between two extended electrode layers, and at least one conductive layer on outer surfaces of two extended electrode layers. Another embodiment provides an ionic polymer device comprising a polymer composite with a plurality of surface features on two opposite surfaces, and at least one conductive layer on each of said two opposite surfaces. One embodiment provides a method of making an ionic polymer device, comprising forming a partially cured polymer-metallic salt layer, reducing the metallic salt to form a plurality of metal particles, thereby forming a first extended electrode layer and a second extended electrode layer at and near opposite surfaces of the ionic polymer device.

摘要翻译： 一个实施方案提供了一种离子聚合物装置，其包括两个包括多个导电颗粒的延伸电极层，其中多个导电颗粒在两个延伸电极层中的每一个中形成浓度梯度，在两个延伸电极层之间形成离子聚合物电介质层， 在两个延伸的电极层的外表面上的至少一个导电层。 另一个实施方案提供了一种离子聚合物装置，其包括在两个相对表面上具有多个表面特征的聚合物复合物，以及在所述两个相对表面中的每一个上的至少一个导电层。 一个实施方案提供了一种制备离子聚合物装置的方法，包括形成部分固化的聚合物金属盐层，还原金属盐以形成多个金属颗粒，由此在其上形成第一延伸电极层和第二延伸电极层， 靠近离子聚合物装置的相对表面。

公开(公告)号：US20100065819A1

公开(公告)日：2010-03-18

申请号：US12311567

申请日：2007-10-05

申请人： Yongxian Wu

发明人： Yongxian Wu

IPC分类号： H01L31/0352 ,  H01L21/306 ,  H01L29/06 ,  H01L29/66

CPC分类号： H01L31/035281 ,  B82Y10/00 ,  H01L29/0665 ,  H01L31/072 ,  Y02E10/50 ,  Y10S438/93 ,  Y10S438/962 ,  Y10S977/762 ,  Y10S977/768 ,  Y10S977/789

摘要： A method of producing silicon nanowires includes providing a substrate in the form of a doped material; formulating an etching solution; and applying an appropriate current density for an appropriate length of time. Related structures and devices composed at least in part from silicon nanowires are also described.

摘要翻译： 一种制造硅纳米线的方法包括提供掺杂材料形式的衬底; 配制蚀刻溶液; 并施加适当的电流密度适当的时间长度。 还描述了至少部分由硅纳米线构成的相关结构和器件。