摘要:
The present application features the use of the somatostatin subtype 3 receptor (SST3) as a target for affecting insulin secretion and for diagnosing diabetes related disorders. Glucose stimulated insulin secretion was found to be stimulated by knocking down expression of SST3 and through the use of a SST3 selective antagonist.
摘要:
The present application features the use of the somatostatin subtype 3 receptor (SST3) as a target for affecting insulin secretion and for diagnosing diabetes related disorders. Glucose stimulated insulin secretion was found to be stimulated by knocking down expression of SST3 and through the use of a SST3 selective antagonist.
摘要:
Methods for identifying OXGR1 modulator useful for the treatment of diabetes and conditions associated with diabetes are provided. Further provided are methods for treating diabetes and conditions associated with diabetes with an OXGR1 agonist.
摘要:
FIG. 1 is a perspective view of a bowl star projector showing my new design; FIG. 2 is a front elevation view thereof; FIG. 3 is a rear elevation view thereof; FIG. 4 is a left side elevation view thereof; FIG. 5 is a right side elevation view thereof; FIG. 6 is a top plan view thereof; and, FIG. 7 is a bottom plan view thereof. The broken lines depict portions of the bowl star projector that form no part of the claimed design.
摘要:
Embodiments of the present foundation for wind turbine generators comprise four structural members: a relatively long central hollow pier, several arm grade beams, a continued grade beam and a continued shear key. The central hollow pier positions in the center of the foundation system, arm grade beams are arranged evenly in radial direction and extend from the pier to the continued grade beam. Continued grade beam is arranged circumferentially in outer periphery and the continued shear key is built below it. Arm grade beams have a varied section with the far end embedding into ground. The top of the continued grade beam matches the top of arm grade beams, while the continued shear key embeds deeper into ground. All structural members are constructed of cast-in-place concrete reinforced with rebars, and all connections are fixed and rigid. The present foundation uses the ground to shape and form the structural members, no formwork, backfilling and compaction is needed.
摘要:
A rotary steerable drilling tool with an electromagnetic steering system can include a drill collar, a bit shaft, an orientation control module, a mud tube, a mud tube coupler, a universal joint, a mud sealing device, and a drill bit. The bit shaft can be mechanically coupled to the drill collar through the universal joint and the orientation control module and rotate about the universal joint. The orientation and the inclination angle of the bit shaft against the drill collar can be controlled by the orientation control module with the electromagnetic steering system. The orientation control module can include an array of electromagnets, an array of permanent magnets, a rotor, and a set of bearings. The orientation control module can be coupled to the bit shaft through the rotor. The movement of the rotor can be driven by the interaction between the array of electromagnets and the array of permanent magnets.
摘要:
This application discloses a new family of inorganic-organic hybrid semiconductor bulk materials built on periodic nanostructured 2D layers of ZnS that emit bright white light with high quantum efficiency. These ZnS-based crystalline inorganic-organic hybrid semiconductors have well defined and precisely controllable crystal structure and composition. Their optical emission properties, including intensity, quantum yield, and color quality, can be systematically tuned by varying the composition of both inorganic and organic components. Methods for preparing these materials, use of these materials as a new type of single-phased white light emitting phosphors, and their applications in making WLED devices are also disclosed.
摘要:
Provided in the present invention are a cocrystal of piperacillin sodium and sulbactam sodium and preparation method thereof, as well as pharmaceutical compositions containing the same and uses thereof in treating infections caused by drug-resistant bacteria, such as a “super bacterium” producing NDM-1 and the like. The cocrystal of piperacillin sodium and sulbactam sodium contains diffraction angles of 14.24°, 16.58°, 16.79°, 17.77°, 19.20°, 20.21°, 20.39°, 23.06°, 27.86° and 32.16° represented by 2θ in an X-ray powder diffraction analysis spectrum.