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1.发明申请公开(公告)号：US20190290855A1
公开(公告)日：2019-09-26
申请号：US16438203
申请日：2019-06-11
申请人： kaleo, Inc.
摘要： Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH-adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.
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2.发明申请公开(公告)号：US20190206220A1
公开(公告)日：2019-07-04
申请号：US16294004
申请日：2019-03-06
申请人： kaleo, Inc.
IPC分类号： G08B21/18 , A61M15/00 , G09B9/00 , H04B1/3827 , A61M5/20 , A61M5/315 , G16H20/17 , A61M15/08 , A61M5/31 , H04W4/80
摘要： In some embodiments, a method includes establishing a communications link between a computing device and an adapter. The adapter is configured to receive at least a portion of a medicament delivery device. A wireless signal is received to maintain the communications link. A relative position between the computing device and the adapter is determined. An alarm is produced when the wireless signal is not received within a time period. The alarm is based on the relative position between the computing device and the adapter.
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3.发明申请公开(公告)号：US20190175837A1
公开(公告)日：2019-06-13
申请号：US16280488
申请日：2019-02-20
申请人： kaleo, Inc.
CPC分类号： A61M5/2033 , A61M5/20 , A61M5/2066 , A61M5/315 , A61M5/3202 , A61M5/3204 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/208 , A61M2005/2086
摘要： An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.
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公开(公告)号：US20190139453A1
公开(公告)日：2019-05-09
申请号：US16196685
申请日：2018-11-20
申请人： kaleo, Inc.
摘要： An apparatus includes a simulated medicament delivery device and an electronic circuit system. The simulated medicament delivery device includes a housing, and is devoid of a medicament delivery mechanism that causes a medicament to be delivered. The electronic circuit system is coupled to the housing and includes an audible output device and a cover. The housing of the medicament delivery device and the cover of the electronic circuit system collectively define an acoustic enclosure. The audible output device is configured to be disposed within the acoustic enclosure.
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公开(公告)号：US20160184535A1
公开(公告)日：2016-06-30
申请号：US15061462
申请日：2016-03-04
申请人： kaleo, Inc.
CPC分类号： A61M15/009 , A61M5/14244 , A61M5/19 , A61M5/2033 , A61M5/2053 , A61M5/3129 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M5/3287 , A61M5/5086 , A61M35/00 , A61M2005/206 , A61M2005/2073 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/587 , A61M2205/8206 , G06F19/00 , G06F19/3456
摘要： An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal.
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6.发明申请MEDICAMENT DELIVERY DEVICE FOR ADMINISTRATION OF OPIOID ANTAGONISTS INCLUDING FORMULATIONS FOR NALOXONE 有权用于管理阿片类拮抗剂的药物输送装置，包括纳洛酮配方公开(公告)号：US20140123974A1
公开(公告)日：2014-05-08
申请号：US14153575
申请日：2014-01-13
申请人： kaleo, Inc.
CPC分类号： A61M5/002 , A61K31/485 , A61M5/2033 , A61M5/2046 , A61M5/2459 , A61M5/3232 , A61M5/5086 , A61M11/00 , A61M11/007 , A61M15/0001 , A61M15/08 , A61M2202/048 , A61M2205/14 , A61M2205/3584 , A61M2205/581 , A61M2205/583 , A61M2205/80 , A61M2205/8206 , A61M2209/06 , A61M2210/0618 , G09B5/04 , G09B19/24
摘要： Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.
摘要翻译： 本文描述了用于施用阿片样物质拮抗剂的药物递送装置。 在一些实施例中，一种装置包括壳体，设置在壳体内的药物容器和设置在壳体内的能量存储构件。 填充药物容器，其纳纳酮组合物包括纳洛酮或其盐，张力调节剂和pH调节剂，由此纳洛酮组合物的重量摩尔渗透压浓度范围为约250-350mOsm，pH范围为约3- 5。 能量存储构件构造成产生输送纳络酮组合物的力。
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公开(公告)号：US20210138152A1
公开(公告)日：2021-05-13
申请号：US17153254
申请日：2021-01-20
申请人： kaleo, Inc.
摘要： An apparatus includes a movable member and a valve coupled to the movable member. The movable member is configured to be disposed within a housing of a medical device and has a first end portion and second end portion. A portion of the first end portion is configured to define a portion of a boundary of a gas chamber. The first end portion defines an opening configured to be in fluid communication between the gas chamber and an area outside the gas chamber. The second end portion is configured to be coupled to a needle configured to deliver a medicament into a body. The valve is configured to selectively allow fluid communication between the gas chamber and the area outside the gas chamber through the opening defined by the first end portion of the movable member.
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公开(公告)号：US20190030247A1
公开(公告)日：2019-01-31
申请号：US16145873
申请日：2018-09-28
申请人： kaleo, Inc.
发明人： Eric S. EDWARDS , Evan T. EDWARDS , Mark J. LICATA , Paul F. MEYERS , David A. WEINZIERL , T. Spencer WILLIAMSON, IV
摘要： A system includes a medicament delivery device and a container configured to receive at least a portion of the medicament delivery device. The medicament delivery device includes an actuator and a first electronic circuit system. The actuator is configured to initiate delivery of a medicament into a body when the actuator is moved from a first position to a second position. The first electronic circuit system is configured to output a first electronic signal when the actuator is moved from the first position to the second position. The container includes a second electronic circuit system configured to receive the first electronic signal. The second electronic circuit system is configured to output a second electronic signal associated with the first electronic signal.
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公开(公告)号：US20180369506A1
公开(公告)日：2018-12-27
申请号：US16119103
申请日：2018-08-31
申请人： kaleo, Inc.
摘要： Medicament delivery devices are described herein. In some embodiments, an apparatus includes a medical injector and an electronic circuit system. The medical injector includes a housing, a medicament container, and a medicament delivery member. The housing defines a first region and a second region. The first region includes the medicament container and is physically isolated from the second region. The electronic circuit system is configured to be disposed within the second region defined by the housing. The electronic circuit system is configured to output an electronic output associated with a use of the medical injector.
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公开(公告)号：US20160235916A1
公开(公告)日：2016-08-18
申请号：US15139826
申请日：2016-04-27
申请人： kaleo, Inc.
发明人： Eric S. EDWARDS , Evan T. EDWARDS , Mark J. LICATA , Paul F. MEYERS , David A. WEINZIERL , T. Spencer WILLIAMSON, IV
CPC分类号： A61M5/20 , A61M5/19 , A61M5/2033 , A61M5/2053 , A61M5/24 , A61M5/2448 , A61M5/3129 , A61M5/315 , A61M5/3204 , A61M5/326 , A61M15/0001 , A61M15/008 , A61M15/009 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/314 , A61M2205/14 , A61M2205/3331 , A61M2205/3368 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3576 , A61M2205/3584 , A61M2205/3592 , A61M2205/43 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , A61M2205/8206 , G06F19/00 , G06F19/3468
摘要： A system includes a medicament delivery device and a container configured to receive at least a portion of the medicament delivery device. The medicament delivery device includes an actuator and a first electronic circuit system. The actuator is configured to initiate delivery of a medicament into a body when the actuator is moved from a first position to a second position. The first electronic circuit system is configured to output a first electronic signal when the actuator is moved from the first position to the second position. The container includes a second electronic circuit system configured to receive the first electronic signal. The second electronic circuit system is configured to output a second electronic signal associated with the first electronic signal.
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