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公开(公告)号:US12234445B2
公开(公告)日:2025-02-25
申请号:US17293832
申请日:2019-12-26
Applicant: Calysta, Inc.
Inventor: Renee M. Saville , Joshua A. Silverman , Vincent Tang , Eric G. Luning , Paloma Rueda , Megan Hsi , Yelena Stegantseva
Abstract: The present disclosure provides methanotrophic bacteria that are modified to produce less glycogen, and methods of using the modified methanotrophic bacteria to produce a desired product, such as protein(s) or metabolite(s).
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公开(公告)号:US12116563B2
公开(公告)日:2024-10-15
申请号:US17732263
申请日:2022-04-28
Applicant: Calysta, Inc.
Inventor: Luan Thanh Nguyen , Arild Johannessen , Graham Ian Aylen , Joshua A. Silverman
CPC classification number: C12M45/04 , C12M21/00 , C12M29/00 , C12M29/18 , C12M29/20 , C12M35/08 , C12M41/40 , C12N1/30 , C12M21/02
Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.
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3.
公开(公告)号:US11572539B2
公开(公告)日:2023-02-07
申请号:US17199981
申请日:2021-03-12
Applicant: Calysta, Inc.
Inventor: Luan Thanh Nguyen , Joshua A. Silverman , Graham Ian Aylen
Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.
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公开(公告)号:US11332706B2
公开(公告)日:2022-05-17
申请号:US16774991
申请日:2020-01-28
Applicant: Calysta, Inc.
Inventor: Luan Thanh Nguyen , Arild Johannessen , Graham Ian Aylen , Joshua A. Silverman
Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.
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公开(公告)号:US20220119851A1
公开(公告)日:2022-04-21
申请号:US17505411
申请日:2021-10-19
Applicant: Calysta, Inc.
Inventor: Celine Schiff-Deb , Lorraine Joan Giver , Renee Michelle Saville , Lisa Marie Newman , Warren Kwan , Chien-Seng Hwang , Eric Luning
IPC: C12P7/6432 , C12N1/12 , C12P7/6434 , C12N1/20 , C12N1/14 , C12N1/16 , C12N5/07 , A23L31/10 , A23L33/135 , A23B4/22 , A23C9/123 , A23L13/00 , A23L17/00
Abstract: The present disclosure provides culture or fermentation media including a biomass or derivative thereof of a hemoprotein-producing C1 metabolizing non-photosynthetic bacterium, methods of culturing cells or tissue with the culture or fermentation medium, and products produced by the culturing methods including food products, food ingredients, phytoprotective bacterial cell products, and other products of interest such as vitamins, fatty acids, amino acid, carotenoids, etc.
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6.
公开(公告)号:US11034930B2
公开(公告)日:2021-06-15
申请号:US16862026
申请日:2020-04-29
Applicant: Calysta, Inc.
Inventor: Luan Thanh Nguyen , Joshua A. Silverman , Graham Ian Aylen
Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.
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公开(公告)号:US09657317B2
公开(公告)日:2017-05-23
申请号:US14344899
申请日:2012-10-17
Applicant: Calysta, Inc.
Inventor: Joshua A. Silverman , Tom Purcell , Jon Edward Ness , Effendi Leonard
Abstract: Provided herein is an alkane-metabolizing cell that is unable to convert propionyl-CoA into methylmalonyl-CoA or 2-metylcitrate synthase. Depending on which enzymes are present in the cell, the cell can produce acrylate or a precursor for the same (e.g., propionate, 3-hydroxypropionyl-CoA, 3-hydroxypropionate, acrylyl-CoA) that can be readily converted to acrylate enzymatically (e.g., in the cell) or by chemical treatment. In one embodiment, the cell may contain a cytochrome P450 or alkane oxidase enzyme that allows the production of 3-hydroxypropionyl-CoA, which can be readily converted to 3-hydroxypropionate. In order to make such compounds, the cell may be grown in the presence of an odd-numbered chain alkane (e.g., pentane or heptane), although another odd-numbered chain alkane may be used. In another embodiment, the cell may contain acyl-CoA oxidase, enoyl-CoA hydratase, and hydrolase.
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8.
公开(公告)号:US20240052295A1
公开(公告)日:2024-02-15
申请号:US17766625
申请日:2020-10-07
Applicant: Calysta, Inc.
Inventor: Yelena Stegantseva , Lisa Marie Newman , Warren Kwan , Chien-Seng Hwang , Lorraine Joan Giver , Celine Schiff-Deb
IPC: C12N1/20 , C07K14/195
CPC classification number: C12N1/20 , C07K14/195
Abstract: The present disclosure provides method for generating biomass by culturing methanotrophic bacteria under low copper conditions. Also provided are generated biomass and protein isolate prepared from the biomass.
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公开(公告)号:US11480581B2
公开(公告)日:2022-10-25
申请号:US16900599
申请日:2020-06-12
Applicant: Calysta, Inc.
Inventor: Sungwon Lee , Allan LeBlanc
Abstract: The present disclosure provides methods of identifying or certifying an animal that consumed a traceable diet comprising a C1 metabolizing microorganism.
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公开(公告)号:US10538730B2
公开(公告)日:2020-01-21
申请号:US16405587
申请日:2019-05-07
Applicant: Calysta, Inc.
Inventor: Luan Thanh Nguyen , Arild Johannessen , Graham Ian Aylen , Joshua A. Silverman
Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.
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