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1.发明申请COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF 1-ALKENES IN ENGINEERED MICROORGANISMS 审中-公开工程微生物中1-碱基的生成方法的组合物和方法公开(公告)号：US20140186877A1
公开(公告)日：2014-07-03
申请号：US14240118
申请日：2012-08-22
IPC分类号： C12P5/00
摘要： Various 1-alkenes, including 1-nonadecene and 1-octadecene, are synthesized by the engineered microorganisms and methods of the invention. In certain embodiments, the microorganisms comprise a recombinant alpha-olefin-associated enzyme. This enzyme may be expressed in combination with a recombinant alkene synthase pathway-related gene. The engineered microorganisms may be photosynthetic microorganisms such as cyanobacteria.
摘要翻译： 各种1-烯烃，包括1-十九烯和1-十八碳烯，是通过工程改造的微生物和本发明的方法合成的。 在某些实施方案中，微生物包含重组α-烯烃相关酶。 该酶可以与重组烯烃合酶途径相关基因组合表达。 工程微生物可以是光合微生物，如蓝细菌。
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2.发明授权公开(公告)号：US08580542B2
公开(公告)日：2013-11-12
申请号：US13370654
申请日：2012-02-10
申请人： Christian P. Ridley
发明人： Christian P. Ridley
CPC分类号： C12N9/00 , C07K2319/00 , C12N9/1029 , C12N15/62 , C12P5/026
摘要： The NonA alkene synthase in Synechococcus sp. displays selective synthesis of 1-nonadecene. Heterologous recombination of a domain, i.e. the acyl binding domain, with other acyl binding proteins, affects acyl substrate chain-length binding selectivity and therefore the chain-length of the synthesized 1-alkenes. Compositions and methods are provided to selectively synthesize 1-alkenes of various chain lengths.
摘要翻译： 聚合球菌中的NonA烯烃合酶 显示1-十九烯的选择性合成。 结构域（即酰基结合结构域）与其他酰基结合蛋白的异源重组影响酰基底物链长度结合选择性，因此影响合成的1-烯烃的链长度。 提供组合物和方法以选择性合成各种链长的1-烯烃。
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3.发明申请Photobioreactors, Solar Energy Gathering Systems, and Thermal Control Methods 审中-公开光生物反应器，太阳能收集系统和热控制方法公开(公告)号：US20130244320A1
公开(公告)日：2013-09-19
申请号：US13651035
申请日：2012-10-12
IPC分类号： C12M1/00
摘要： The present invention provides photobioreactors, solar energy gathering systems, and methods for thermal control of a culture medium containing a phototrophic organism in a photobioreactor, that allow temperature control in a cost effective manner, reducing the energy required for temperature control of a culture medium containing phototrophic microorganisms in a photobioreactor.
摘要翻译： 本发明提供了光生物反应器，太阳能收集系统和用于热光控制在光生物反应器中含有光养生物的培养基的方法，其以成本有效的方式进行温度控制，降低了对含有 光生物反应器中的光养微生物。
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公开(公告)号：US08216816B2
公开(公告)日：2012-07-10
申请号：US13243194
申请日：2011-09-23
CPC分类号： C12P7/065 , C12N1/20 , C12N9/00 , C12N9/0006 , C12N9/0008 , C12N9/001 , C12N9/0083 , C12N9/1007 , C12N9/1029 , C12N9/88 , C12N15/74 , C12P1/04 , C12P5/00 , C12P5/02 , C12P5/026 , C12P7/00 , C12P7/6409 , C12P7/6427 , C12P7/6436 , C12P7/6463 , C12P7/6472 , C12P7/649 , C12P13/04 , C12R1/01 , C12Y103/03006 , Y02E50/13 , Y02E50/17 , Y02E50/18 , Y02E50/343
摘要： The present disclosure relates to methods and compositions for engineering photoautotrophic organisms to convert carbon dioxide and light into fatty acid esters and other molecules, including biofuels. The molecules are then secreted by the organism into a growth medium.
摘要翻译： 本公开涉及用于将光自养生物工程化以将二氧化碳和光转化成脂肪酸酯和其它分子（包括生物燃料）的方法和组合物。 然后分子被生物体分泌到生长培养基中。
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公开(公告)号：US20110284361A1
公开(公告)日：2011-11-24
申请号：US13204183
申请日：2011-08-05
申请人： Yizu Zhu , Johan van Walsem
发明人： Yizu Zhu , Johan van Walsem
CPC分类号： B01D3/14 , B01D5/0036 , B01D5/006
摘要： The present invention provides fractional condensation apparatuses, systems and methods that can recover volatile products from highly diluted liquid and vapor feed mixtures with high purity and recovery yield, both in batch and continuous distillation, while being also designed to achieve low-cost and efficient recovery processes. Single apparatuses and columns can be connected to each other to expand or shrink the column length for desired separation. The apparatuses, systems and methods can be applied to separate mixtures with both narrow and wide boiling point ranges.
摘要翻译： 本发明提供了分批冷凝装置，系统和方法，其可以在分批和连续蒸馏中以高纯度和回收产率从高度稀释的液体和蒸汽进料混合物中回收挥发性产物，同时还被设计成实现低成本和有效的回收 过程。 单个装置和柱可以彼此连接以扩大或缩小列长度以进行期望的分离。 装置，系统和方法可以应用于分离窄和沸点范围的混合物。
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6.发明授权Methods and compositions for the recombinant biosynthesis of fatty acids and esters 有权用于脂肪酸和酯的重组生物合成的方法和组合物公开(公告)号：US08048654B2
公开(公告)日：2011-11-01
申请号：US12876056
申请日：2010-09-03
申请人： David Arthur Berry , Noubar Boghos Afeyan , Frank Anthony Skraly , Christian Perry Ridley , Dan Eric Robertson , Regina Wilpiszeski , Martha Sholl
发明人： David Arthur Berry , Noubar Boghos Afeyan , Frank Anthony Skraly , Christian Perry Ridley , Dan Eric Robertson , Regina Wilpiszeski , Martha Sholl
IPC分类号： C12P7/64
CPC分类号： C10L1/026 , C10L2200/0476 , C10L2270/026 , C12N15/79 , C12P7/649 , C12Y602/01003 , Y02E50/13 , Y02E50/17
摘要： The present disclosure identifies methods and compositions for modifying photoautotrophic organisms, such that the organisms efficiently convert carbon dioxide and light into compounds such as esters and fatty acids. In certain embodiments, the compounds produced are secreted into the medium used to culture the organisms.
摘要翻译： 本公开内容确定了修饰光自养生物的方法和组合物，使得生物有效地将二氧化碳和光转化为化合物如酯和脂肪酸。 在某些实施方案中，所生产的化合物分泌到用于培养生物体的培养基中。
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公开(公告)号：US08026399B2
公开(公告)日：2011-09-27
申请号：US13061122
申请日：2010-07-28
申请人： Yizu Zhu , Johan van Walsem
发明人： Yizu Zhu , Johan van Walsem
IPC分类号： C07C27/26
CPC分类号： B01D3/14 , B01D5/0036 , B01D5/006
摘要： The present invention provides fractional condensation apparatuses, systems and methods that can recover volatile products from highly diluted liquid and vapor feed mixtures with high purity and recovery yield, both in batch and continuous distillation, while being also designed to achieve low-cost and efficient recovery processes. Single apparatuses and columns can be connected to each other to expand or shrink the column length for desired separation. The apparatuses, systems and methods can be applied to separate mixtures with both narrow and wide boiling point ranges.
摘要翻译： 本发明提供了分批冷凝装置，系统和方法，其可以在分批和连续蒸馏中以高纯度和回收产率从高度稀释的液体和蒸汽进料混合物中回收挥发性产物，同时还被设计成实现低成本和有效的回收 过程。 单个装置和柱可以彼此连接以扩大或缩小列长度以进行期望的分离。 这些装置，系统和方法可以应用于分开窄和沸点范围的混合物。
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公开(公告)号：US09074225B2
公开(公告)日：2015-07-07
申请号：US12821107
申请日：2010-06-22
CPC分类号： C12P5/026 , C12N1/12 , C12N9/1029
摘要： Various 1-alkenes, including 1-nonadecene and 1-octadecene, are synthesized by the engineered microorganisms and methods of the invention. In certain embodiments, the microorganisms comprise recombinant 1-alkene synthases. The engineered microorganisms may be photosynthetic microorganisms such as cyanobacteria.
摘要翻译： 各种1-烯烃，包括1-十九烯和1-十八碳烯，是通过工程改造的微生物和本发明的方法合成的。 在某些实施方案中，微生物包含重组1-烯烃合酶。 工程微生物可以是光合微生物，如蓝细菌。
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公开(公告)号：US09029124B2
公开(公告)日：2015-05-12
申请号：US13428658
申请日：2012-03-23
申请人： Dan Eric Robertson , Christian Perry Ridley , Nikos Basil Reppas , Jacob Carter Harrison , Michael Connor , Frank Anthony Skraly
发明人： Dan Eric Robertson , Christian Perry Ridley , Nikos Basil Reppas , Jacob Carter Harrison , Michael Connor , Frank Anthony Skraly
CPC分类号： C12N9/0008 , C12N9/0071 , C12P5/02 , C12P5/026 , C12P7/04
摘要： The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently convert inorganic carbon and light into n-alkanes, and in particular the use of such organisms for the commercial production of n-alkanes and related molecules.
摘要翻译： 本公开内容确定用于将光自养生物修饰为宿主的方法和组合物，使得生物体将无机碳和光有效地转化为正烷烃，特别是使用这些生物来商业生产正烷烃和相关分子。
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10.发明申请Photobioreactors, Solar Energy Gathering Systems, And Thermal Control Methods 审中-公开光生物反应器，太阳能收集系统和热控制方法公开(公告)号：US20140329223A1
公开(公告)日：2014-11-06
申请号：US14245502
申请日：2014-04-04
摘要： The present invention provides photobioreactors, solar energy gathering systems, and methods for thermal control of a culture medium containing a phototrophic organism in a photobioreactor, that allow temperature control in a cost effective manner, reducing the energy required for temperature control of a culture medium containing phototrophic microorganisms in a photobioreactor.
摘要翻译： 本发明提供了光生物反应器，太阳能收集系统和用于热光控制在光生物反应器中含有光养生物的培养基的方法，其以成本有效的方式进行温度控制，降低了对含有 光生物反应器中的光养微生物。
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