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    Detection beyond the standard radiation noise limit using spectrally selective absorption
    2.
    发明授权
    Detection beyond the standard radiation noise limit using spectrally selective absorption 有权
    使用光谱选择性吸收检测超出标准辐射噪声极限

    公开(公告)号：US08629398B2

    公开(公告)日：2014-01-14

    申请号：US12996704

    申请日：2009-05-29

    申请人： Joseph J. Talghader ,  Ryan P. Shea ,  Anand S. Gawarikar

    发明人： Joseph J. Talghader ,  Ryan P. Shea ,  Anand S. Gawarikar

    IPC分类号： G01J5/20 ,  G01J5/02

    CPC分类号： G01J5/02 ,  G01J5/023 ,  G01J5/04 ,  G01J5/046 ,  G01J5/08 ,  G01J5/0853

    摘要： High sensitivity thermal detectors that perform beyond the blackbody radiation noise limit are described. Thermal detectors, as described herein, use spectrally selective materials that absorb strongly in the wavelength region of the desired signal but only weakly or not at all in the primary thermal emission band. Exemplary devices that can be made in accordance with the present invention include microbolometers containing semiconductors that absorb in the MWIR and/or THz range but not the LWIR.

    摘要翻译： 描述超高于黑体辐射噪声极限的高灵敏度热探测器。 如本文所述的热检测器使用光谱选择性材料，其在所需信号的波长区域中强烈吸收，但仅在初级热发射带中仅弱或不完全吸收。 可以根据本发明制造的示例性装置包括含有在MWIR和/或THz范围内而不是LWIR吸收的半导体的微伏热计。

    Method of removing organic volatile and semi-volatile contaminants from an aqueous solution
    5.
    发明授权
    Method of removing organic volatile and semi-volatile contaminants from an aqueous solution 失效
    从水溶液中除去有机挥发性和半挥发性污染物的方法

    公开(公告)号：US4960520A

    公开(公告)日：1990-10-02

    申请号：US380003

    申请日：1989-07-14

    申请人： Michael J. Semmens

    发明人： Michael J. Semmens

    IPC分类号： B01D19/00 ,  B01D61/00 ,  B01D61/36

    CPC分类号： B01D61/364 ,  B01D19/0031 ,  B01D61/00

    摘要： Contaminated water is pumped through hollow fiber membranes of microporous polypropylene with a very thin outside coating of plasma polymerized disiloxane. The fibers are potted in a module which resembles a shell and tube heat exchanger. Strippant is pumped through the shell side of the module and over the outside of the fibers. The volatile and semi-volatile contaminants in the water diffuse across the membrane and dissolve into the oil. The process results in clean water and a smaller volume of more highly contaminated oil.

    摘要翻译： 污染的水通过具有非常薄的等离子体聚合二硅氧烷外涂层的微孔聚丙烯的中空纤维膜泵送。 纤维被封装在类似于壳管式热交换器的模块中。 剥离剂泵送通过模块的外壳侧和纤维的外侧。 水中的挥发性和半挥发性污染物通过膜扩散并溶解到油中。 该过程产生清洁的水和较少体积的更高污染的油。

    Methylotroph cloning vehicle
    6.
    发明授权
    Methylotroph cloning vehicle 失效
    甲状腺营养克隆载体

    公开(公告)号：US4824786A

    公开(公告)日：1989-04-25

    申请号：US107244

    申请日：1987-11-13

    申请人： Richard S. Hanson ,  Larry N. Allen

    发明人： Richard S. Hanson ,  Larry N. Allen

    IPC分类号： C12N15/74 ,  C12N15/78 ,  C12N1/20 ,  C12N15/00

    CPC分类号： C12N15/78 ,  C12N15/74

    摘要： A cloning vehicle comprising: a replication determinant effective for replicating the vehicle in a non-C.sub.1 -utilizing host and in a C.sub.1 -utilizing host; DNA effective to allow the vehicle to be mobilized from the non-C.sub.1 -utilizing host to the C.sub.1 -utilizing host; DNA providing resistance to two antibiotics to which the wild-type C.sub.1 -utilizing host is susceptible, each of the antibiotic resistance markers having a recognition site for a restriction endonuclease; a cos site; and a means for preventing replication in the C.sub.1 -utilizing host. The vehicle is used for complementation mapping as follows. DNA comprising a gene from the C.sub.1 -utilizing organism is inserted at the restriction nuclease recognition site, inactivating the antibiotic resistance marker at that site. The vehicle can then be used to form a cosmid structure to infect the non-C.sub.1 -utilizing (e.g., E. coli) host, and then conjugated with a selected C.sub.1 -utilizing mutant. Resistance to the other antibiotic by the mutant is a marker of the conjugation. Other phenotypical changes in the mutant, e.g., loss of an auxotrophic trait, is attributed to the C.sub.1 gene. The vector is also used to inactivate genes whose protein products catalyze side reactions that divert compounds from a biosynthetic pathway to a desired product, thereby producing an organism that makes the desired product in higher yields.

    摘要翻译： 一种克隆载体，其包含：有效用于在非C1利用宿主和C1利用宿主中复制所述载体的复制决定簇; 有效地使车辆从非C1利用主体移动到C1利用主机的DNA; 提供对野生型C1利用宿主易感的两种抗生素的抗性的DNA，每种抗生素抗性标记具有限制性内切核酸酶的识别位点; 一个cos站点; 以及用于在C1利用宿主中防止复制的手段。 车辆用于互补映射如下。 将包含来自C1利用生物体的基因的DNA插入限制性核酸酶识别位点，使该位点处的抗生素抗性标记失活。 然后载体可以用于形成粘粒结构以感染非C1利用（例如，大肠杆菌）宿主，然后与所选的C1-利用突变体缀合。 突变体对其他抗生素的抗性是缀合的标记。 突变体的其他表型变化，例如营养缺陷性状的丧失归因于C1基因。 该载体还用于灭活其蛋白质产物催化将化合物从生物合成途径转移至所需产物的副反应的基因，从而产生以更高产率制备所需产物的生物体。

    Alkoxyalkanoate esters of arabinofuranosyladenine
    7.
    发明授权
    Alkoxyalkanoate esters of arabinofuranosyladenine 失效
    阿拉伯呋喃糖基腺嘌呤的烷氧基酸酯

    公开(公告)号：US4338310A

    公开(公告)日：1982-07-06

    申请号：US225567

    申请日：1981-01-16

    申请人： Robert Vince

    发明人： Robert Vince

    IPC分类号： C07D473/00 ,  C07H19/16 ,  A61K31/70

    CPC分类号： C07D473/00 ,  C07H19/16

    摘要： Alkoxyalkanoate esters of vidarabine of the formula ##STR1## wherein R.sub.x, R.sub.y and R.sub.z are ##STR2## or hydrogen and wherein R.sub.1 is lower alkyl and R.sub.2 is lower alkylene, which compounds are useful in treating susceptible viral infections, are disclosed.

    摘要翻译： 其中Rx，Ry和Rz是“或”氢，并且其中R 1是低级烷基，R 2是低级亚烷基，该化合物可用于治疗易感病毒感染的阿片酸异戊酸酯。

    Porous surface solar energy receiver
    8.
    发明授权
    Porous surface solar energy receiver 失效
    多孔表面太阳能接收器

    公开(公告)号：US4318393A

    公开(公告)日：1982-03-09

    申请号：US910609

    申请日：1978-05-30

    申请人： Richard J. Goldstein

    发明人： Richard J. Goldstein

    IPC分类号： F24S10/80 ,  F24S20/20 ,  F24J3/02

    CPC分类号： F24J2/07 ,  F24J2/28 ,  F24J2002/1076 ,  Y02E10/41 ,  Y02E10/44

    摘要： A porous surface receiver and concentrator of reflected solar radiation. The receiver is part of a moderately or strongly concentrating solar collector such as a solar power tower system. In the latter, radiation is reflected by a plurality of heliostats disposed about the tower on which the receiver is mounted. The solar radiation is reflected onto the central heat transfer receiver where the energy is transferred to a working fluid. Atmospheric air is used as the working fluid. The air is drawn through the porous matrix of the receiver surface and is heated to a high temperature in the range of 500.degree. to 1500.degree. C. with only a moderate pressure drop. The radiant heat flux input may be hundreds of times the incoming solar flux to the earth surface. The hot air can be used in a thermal storage system, or directly in a heat exchanger, or the like.

    摘要翻译： 反射太阳辐射的多孔表面接收器和集中器。 接收器是中等或强烈集中的太阳能收集器（如太阳能发电塔系统）的一部分。 在后者中，辐射被设置在其上安装有接收器的塔的周围的多个定日镜反射。 太阳辐射被反射到中心传热接收器上，其中能量被转移到工作流体。 大气中的空气被用作工作流体。 空气被吸收到接收器表面的多孔基体中，并被加热至500〜1500℃的高温，只有适度的压降。 辐射热通量输入可能是到地球表面的入射太阳能通量的几百倍。 热空气可以用在热存储系统中，或直接在热交换器等中使用。

    Implantable drug infusion regulator
    9.
    发明授权
    Implantable drug infusion regulator 失效
    植入式药物输注调节剂

    公开(公告)号：US4299220A

    公开(公告)日：1981-11-10

    申请号：US35535

    申请日：1979-05-03

    申请人： Frank D. Dorman

    发明人： Frank D. Dorman

    IPC分类号： A61D7/00 ,  A61M1/00 ,  A61M1/36 ,  A61M5/142 ,  A61M5/168 ,  A61M7/00

    CPC分类号： A61M5/16881 ,  A61M5/14276 ,  A61M2005/14264 ,  A61M5/141

    摘要： An implantable flow regulator for the infusion of drugs into an animal body from a pressure actuated drug delivery device, such as an implantable infusion pump. The flow regulator comprises a body having a shallow cavity divided into two chambers by a flexible diaphragm. The first of these chambers is a pressure sensing chamber. The other is a valving chamber through which the drug flows, the outlet from that chamber being centrally disposed underlying the diaphragm whereby flexing of the diaphragm in one direction as a result of increased pressure in the other chamber contacts an elastomeric sealing ring around the outlet and closes off the flow path. At least one capillary restrictor is disposed in the flow line between the drug delivery device and flow regulator. The pressure drop across this restrictor governs operation of the flow regulator valve.

    摘要翻译： 一种可植入流量调节器，用于从压力致动的药物输送装置（例如可植入输液泵）将药物输入动物体内。 流量调节器包括具有通过柔性隔膜分成两个腔室的浅腔的主体。 这些室中的第一个是压力感测室。 另一个是药物流过的阀室，来自该腔室的出口居中设置在隔膜下方，由于另一腔室中的压力增加，膜片在一个方向上的挠曲与出口周围的弹性密封环接触， 封闭流路。 至少一个毛细管限制器设置在药物输送装置和流量调节器之间的流动管线中。 该限流器上的压降决定了流量调节阀的运行。

    Cystic fibrosis detection method
    10.
    发明授权
    Cystic fibrosis detection method 失效
    囊性纤维化检测方法

    公开(公告)号：US4273869A

    公开(公告)日：1981-06-16

    申请号：US30179

    申请日：1979-04-16

    申请人： Burton L. Shapiro

    发明人： Burton L. Shapiro

    IPC分类号： C12Q1/32 ,  G01N33/50

    CPC分类号： G01N33/5091 ,  C12Q1/32 ,  Y10S435/81

    摘要： A method of diagnosing cystic fibrosis, identifying carriers for cystic fibrosis, and non-carriers or "normal" persons. Heretofore, no carrier or prenatal detection procedure for cystic fibrosis existed. The detection method is based on the discovery of the genetic abnormality or biochemical defect in cystic fibrosis, which occurs in mitochondria, minute bodies found in the cytoplasma of most cells which are the principal energy source of the cell and contain the cytochrome enzymes of terminal electron transport. The method comprises an assay carried out on preparations derived from human cells possessing mitochondria. The assay may be a kinetic assay of the enzyme complex of the energy conserving site of the mitochondrial electron transport system of the cells or an assay of mitochondrial activity governed by the enzyme complex. The assay is then evaluated by comparison with standards established as the result of similar assays of cells of other subjects of known condition. The assays provide determination of characteristics which differ in the three types of individuals (normal, carrier and affected) and provide a basis for their distinction.

    摘要翻译： 诊断囊性纤维化的方法，确定囊性纤维化的携带者，以及非携带者或“正常”人。 迄今为止，没有存在囊性纤维化的载体或产前检测程序。 检测方法是基于发现在囊性纤维化中的遗传异常或生物化学缺陷，其发生在线粒体中，在作为细胞的主要能量源的大多数细胞的细胞质中发现的微小体，并且含有末端电子的细胞色素酶 运输。 该方法包括对源自具有线粒体的人细胞的制剂进行测定。 该测定可以是细胞的线粒体电子传递系统的节能位点的酶复合物的动力学测定或由酶复合物控制的线粒体活性的测定。 然后通过与作为已知病症的其他受试者的细胞的相似测定的结果建立的标准进行比较来评估测定。 这些测定提供了三种类型（正常，携带者和受影响者）不同的特征的确定，并为它们的区别提供了依据。