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    Mold and molding apparatus for embedding biological specimen in a block and related methods
    1.
    发明授权
    Mold and molding apparatus for embedding biological specimen in a block and related methods 有权

    公开(公告)号：US10429281B2

    公开(公告)日：2019-10-01

    申请号：US15012751

    申请日：2016-02-01

    Applicant: UC-CARE LTD.

    Inventor： Alex Pasternak ,  Keren Shapira-Schweitzer

    IPC: G01N1/36 ,  G01N1/28 ,  B29C37/00 ,  B29C39/26 ,  B29C33/76 ,  B29C39/10 ,  B29C39/02 ,  B29C33/42 ,  B29B13/00 ,  B29C43/18 ,  G01N1/31

    Abstract: A molding apparatus for producing a biological tissue embedded in a block of an embedding material. The molding apparatus comprising a mold comprising a compartment configured for containing the embedding material. The compartment having a compartment floor and at least one wall extending upwards from said compartment floor. The compartment comprises at least one depression extending downwards from the compartment floor. The molding apparatus further comprising a sample sheet configured to attach to the biological tissue and hold the biological tissue thereon. The sample sheet being further dimensioned to be positioned in the compartment and to be constrained to the position thereof, at least along one direction, by the compartment. The depression is configured for accepting the biological tissue at least partially therein. Thereby the molding apparatus being configured for producing a block of an embedding material having at least one protrusion associated with the at least one depression wherein the biological tissue, attached to the sample sheet, is embedded at least partially in the protrusion.

    MOLD AND MOLDING APPARATUS FOR EMBEDDING BIOLOGICAL SPECIMEN IN A BLOCK AND RELATED METHODS
    3.
    发明申请
    MOLD AND MOLDING APPARATUS FOR EMBEDDING BIOLOGICAL SPECIMEN IN A BLOCK AND RELATED METHODS 审中-公开
    用于嵌入生物样本的模具和模具设备及相关方法

    公开(公告)号：US20160169778A1

    公开(公告)日：2016-06-16

    申请号：US15012751

    申请日：2016-02-01

    Applicant: UC-CARE LTD.

    Inventor： Alex PASTERNAK ,  Keren SHAPIRA-SCHWEITZER

    IPC: G01N1/36 ,  B29C43/18

    CPC classification number: G01N1/36 ,  B29B13/00 ,  B29C33/42 ,  B29C33/76 ,  B29C37/0053 ,  B29C39/026 ,  B29C39/10 ,  B29C39/26 ,  B29C43/18 ,  B29C2033/426 ,  G01N1/28 ,  G01N2001/315 ,  G01N2001/362 ,  G01N2001/366 ,  G01N2001/368

    Abstract: A molding apparatus for producing a biological tissue embedded in a block of an embedding material. The molding apparatus comprising a mold comprising a compartment configured for containing the embedding material. The compartment having a compartment floor and at least one wall extending upwards from said compartment floor. The compartment comprises at least one depression extending downwards from the compartment floor. The molding apparatus further comprising a sample sheet configured to attach to the biological tissue and hold the biological tissue thereon. The sample sheet being further dimensioned to be positioned in the compartment and to be constrained to the position thereof, at least along one direction, by the compartment. The depression is configured for accepting the biological tissue at least partially therein. Thereby the molding apparatus being configured for producing a block of an embedding material having at least one protrusion associated with the at least one depression wherein the biological tissue, attached to the sample sheet, is embedded at least partially in the protrusion.

    Abstract translation: 一种用于生产嵌入嵌入材料块中的生物组织的成型装置。 模制设备包括模具，该模具包括被配置为容纳嵌入材料的室。 所述隔间具有隔间地板和从所述隔间地板向上延伸的至少一个壁。 隔室包括从隔室底部向下延伸的至少一个凹部。 所述成型设备还包括样品片，所述样品片构造成附着到所述生物组织并将所述生物组织保持在其上。 样品片的尺寸进一步确定为位于隔室中并且至少沿着一个方向被隔室限制到其位置。 凹陷构造成用于至少部分地接纳生物组织。 因此，模制设备被配置用于生产嵌入材料块，其具有与至少一个凹部相关联的至少一个突起，其中附接到样品片的生物组织至少部分地嵌入在突起中。

    Mold and molding apparatus for embedding biological specimen in a block and related methods
    4.
    发明授权
    Mold and molding apparatus for embedding biological specimen in a block and related methods 有权
    用于将生物样品嵌入块中的模具和成型装置及相关方法

    公开(公告)号：US09250167B2

    公开(公告)日：2016-02-02

    申请号：US14377854

    申请日：2013-12-17

    Applicant: UC-CARE LTD.

    Inventor： Alex Pasternak ,  Keren Schweizer

    IPC: B29C39/10 ,  G01N1/36 ,  B29B13/00

    CPC classification number: G01N1/36 ,  B29B13/00 ,  B29C43/18 ,  G01N2001/366

    Abstract: A mold for producing a biological tissue embedded in a block of an embedding material is provided. The mold comprises a compartment having a compartment floor and a depression extending downwards from the compartment floor. A molding apparatus, comprising a mold and a press for pressing a sample sheet onto the compartment floor of the mold is provided. The press comprises a foot configured to enter at least partially into the compartment and press a sample tissue, at least partially into the depression. A method of embedding a biological tissue in an embedding material using a mold as described herein is provided. A cleaning device configured for removing excess embedding materials from the press of the molding apparatus is provided.

    Abstract translation: 提供一种用于生产嵌入嵌入材料块中的生物组织的模具。 模具包括具有隔室底板和从隔室底板向下延伸的凹部的隔间。 提供了一种模制设备，其包括用于将样品片材压到模具的隔室底板上的模具和压力机。 压力机包括构造成至少部分地进入隔室并将样品组织至少部分地压入凹陷中的脚。 提供了使用如本文所述的模具将生物组织嵌入嵌入材料的方法。 提供了一种清洁装置，其被构造成用于从模制设备的压机中去除多余的嵌入材料。

    FOCUSED PROSTATE CANCER TREATMENT SYSTEM AND METHOD
    5.
    发明申请
    FOCUSED PROSTATE CANCER TREATMENT SYSTEM AND METHOD 有权
    聚焦前列腺癌治疗系统及方法

    公开(公告)号：US20130090554A1

    公开(公告)日：2013-04-11

    申请号：US13805535

    申请日：2011-06-23

    Applicant: Roni Zvuloni ,  Shaike Schatzberger

    Inventor： Roni Zvuloni ,  Shaike Schatzberger

    IPC: A61B5/06 ,  A61B8/12

    CPC classification number: A61B5/061 ,  A61B8/12 ,  A61B10/0241 ,  A61B34/25 ,  A61B2017/00274 ,  A61B2018/00547 ,  A61B2034/105 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/378

    Abstract: Systems and methods for locating lesions in a prostate or other organ during a first intervention session, and for using that lesion location information during a second intervention session are presented. A module for detecting and reporting the position of a prostate in real time is disclosed. The module comprises a sensor which detects and electronic signal. An image registration system for mapping first-session 3D model information to a second-session 3D model is also presented, as is a prostate modeling facilitation tool which comprises a set of predefined 3D models of the prostate.

    Abstract translation: 呈现在第一次干预会话期间用于定位前列腺或其他器官中的病变的系统和方法，以及在第二次干预期间期间使用该病变位置信息。 公开了一种用于实时检测和报告前列腺位置的模块。 该模块包括检测和电子信号的传感器。 还提出了用于将第一会话3D模型信息映射到第二会话3D模型的图像注册系统，前列腺建模促进工具还包括一组前列腺的预定3D模型。

    System and methods for processing a biopsy sample
    6.
    发明授权
    System and methods for processing a biopsy sample 有权

    公开(公告)号：US10092279B2

    公开(公告)日：2018-10-09

    申请号：US14775415

    申请日：2014-03-13

    Applicant: UC-CARE LTD.

    Inventor： Alex Pasternak ,  Tomer Schatzberger ,  Shaike Schatzberger ,  Moshe Ebenstein

    IPC: G06T7/00 ,  A61B10/04 ,  A61B8/08 ,  A61B8/12 ,  A61B10/02 ,  A61B8/00 ,  A61B90/13 ,  A61B90/50 ,  A61B5/055 ,  A61B90/00 ,  A61B34/20 ,  A61B34/10

    Abstract: A system further comprises a processing unit functionally associated with the display, wherein the processing unit comprises an image processing module. The system further comprises a camera functionally associated with the processing unit via a communication channel for transferring images from the camera to the processing unit and configured to obtain images of a biopsy sample obtained from the body of the patient. The processing unit is configured to receive image data from an imaging modality capable of obtaining images of internal patient's body parts not directly visible from outside the body, and to display to a user on a display images related to the image data. The processing unit is further configured to generate, from at least one image of a biopsy sample and using the image processing module, a processed image related to the biopsy sample, and to display the processed image on the display.

    Method and apparatus for positioning a surgical instrument
    9.
    发明授权
    Method and apparatus for positioning a surgical instrument 有权
    用于定位外科器械的方法和装置

    公开(公告)号：US07670333B2

    公开(公告)日：2010-03-02

    申请号：US10517768

    申请日：2003-06-26

    Applicant: Shaike Schatzberger

    Inventor： Shaike Schatzberger

    IPC: A61B17/00

    CPC classification number: A61B8/0841 ,  A61B5/055 ,  A61B6/12 ,  A61B8/12 ,  A61B17/00234 ,  A61B18/02 ,  A61B90/11 ,  A61B2017/00274 ,  A61B2018/00547

    Abstract: Presented are methods and apparatus for delivering a surgical instrument to a treatment site within the body of a subject, enabling accurate placement of surgical tools in areas not directly visible to a surgeon during a surgical procedure, while reducing or eliminating need for real-time imaging modalities to guide placement of those surgical tools. A treatment tool is guided to a treatment site by placing a guiding element at a reference site within a body of a subject, the reference site having a known spatial relationship to the treatment site, and utilizing a positioning tool to guide a treatment tool to a locus so positioned with respect to that guiding element that the spatial relationship between that guiding element and that locus is substantially similar to the spatial relationship known to exist between the reference site and the treatment site, thereby positioning the treatment tool substantially at the treatment site. Methods and apparatus for treatment of Benign Prostate Hyperplasia are also presented.

    Abstract translation: 提出了用于将外科器械递送到受试者体内的治疗部位的方法和装置，能够在外科手术过程中将手术工具准确地放置在外科医生不能直接看到的区域中，同时减少或消除对实时成像的需要 指导这些手术工具的放置的方式。 将治疗工具通过将引导元件放置在受试者身体内的参考部位而引导到治疗部位，参考部位与治疗部位具有已知的空间关系，并且利用定位工具将治疗工具引导到治疗部位 轨迹相对于该引导元件定位，该引导元件与该轨迹之间的空间关系基本上类似于参考部位和处理部位之间已知的空间关系，从而将治疗工具基本上定位在治疗部位。 还提出了治疗良性前列腺增生的方法和装置。

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