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公开(公告)号：US20240350169A1
公开(公告)日：2024-10-24
申请号：US18638080
申请日：2024-04-17
CPC分类号： A61B17/3403 , A61B17/3421 , A61M1/895 , A61B2017/00128 , A61B2017/3413
摘要： Systems and methods for fat injection or liposuction including or involving a cannula that is configured to provide feedback concerning depth within tissue or the environment into which the cannula is placed.
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公开(公告)号：US12102747B2
公开(公告)日：2024-10-01
申请号：US17389420
申请日：2021-07-30
申请人： Lipocosm, LLC
发明人： Roger K. Khouri , Murat Kuru
CPC分类号： A61M1/67 , A61M1/71 , A61M1/84 , A61M1/87 , A61M1/89 , A61M1/892 , A61M1/895 , A61M1/81 , A61M5/14216 , A61M5/1452 , A61M39/24 , A61M2202/0021 , A61M2202/08 , A61M2205/073 , Y10T137/7838 , Y10T137/87249
摘要： A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2.0 to 4.0 mm, a spring loaded syringe holder with a constant force or coiled ribbon spring to apply a substantially constant pressure over the fill excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter/duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner. After the bags are centrifuged to concentrate the fat, the excess fluids are separated and the valve is re-connected to permit the syringe pump to reverse fluid flow to graft the concentrated fat back into the patient.
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公开(公告)号：US12023431B2
公开(公告)日：2024-07-02
申请号：US17534661
申请日：2021-11-24
申请人： Omer Peled , A. Jason Mirabito
发明人： Omer Peled , A. Jason Mirabito
CPC分类号： A61M1/67 , A61L27/3691 , A61L27/3804 , A61L27/3834 , A61M1/60 , A61M1/88 , A61M1/892 , A61M1/895 , A61M5/19 , A61M2202/08
摘要： A triple-chambered container includes: a main container body with a first chamber which has an opening at its distal end; a main barrel formed and movable longitudinally within the first chamber, the main barrel defining therein a second chamber for receiving fluids, the main barrel further having an apertured stopper at its distal end; a second barrel formed within the main barrel, the second barrel defining a third chamber for receiving fluids, the second barrel being movable longitudinally within and with respect to the main barrel, the second barrel having a distal end which is engageable and disengageable with the apertured stopper; a shaft adapted to fit within the second barrel, the shaft being movable longitudinally within and with respect to the second barrel, the shaft having a distal end which is engageable and disengageable with an aperture in the second barrel; a device for controlling engaging and disengaging of the distal end of the shaft with the aperture of the second barrel. The first chamber, the second chamber and the third chamber may be selectively moved to receive and discharge fluids with respect to one another.
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公开(公告)号：US12005048B2
公开(公告)日：2024-06-11
申请号：US17404276
申请日：2021-08-17
申请人： Michael A. Scarpone
发明人： Michael A. Scarpone
IPC分类号： A61K31/436 , A61K35/35 , A61L27/36 , A61M1/00 , C12M1/00 , C12M1/26 , C12N5/077 , C12N5/0775
CPC分类号： A61K31/436 , A61K35/35 , A61L27/3633 , A61M1/63 , A61M1/71 , A61M1/892 , C12M33/10 , C12M47/04 , C12M47/08 , C12N5/0653 , C12N5/0667 , A61M1/895 , A61M2202/0014 , A61M2202/0021 , A61M2202/095 , A61M2205/3331 , A61M2205/3365
摘要： Methods and devices are disclosed for processing stromal precursor cells (i.e., cells which can differentiate into connective tissue cells, such as in muscles, ligaments, or tendons) which can be obtained from fatty tissue extracts obtained via liposuction. Normal processing of a liposuction extract involves centrifugation, to concentrate the stromal cells into a semi-concentrated form called “spun fat”. That “spun fat” can then be treated by mechanical processing (such as pressure-driven extrusion through 0.5 mm holes) under conditions which can gently pry the stromal cells away from extra-cellular collagen fibers and other debris in the “spun fat”. The extruded mixture is then centrifuged again, to separate a highly-enriched population of stromal cells which is suited for injection back into the patient (along with platelet cells, if desired, to further promote tissue repair or regeneration).
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公开(公告)号：US11672899B2
公开(公告)日：2023-06-13
申请号：US16520653
申请日：2019-07-24
申请人： HEALEON LLC
发明人： Ben M. Khalaj
CPC分类号： A61M1/892 , B26D1/03 , B26D3/185 , B26D3/28 , B26D7/0658 , B26D11/00 , C12M45/02 , A61L27/3691 , A61M1/895 , A61M2202/08 , B26D2011/005
摘要： A deagglomerator for use in resizing masses of cells. The deagglomerator may include a plurality of apertures defined by a plurality of front and back edges. The masses of cells may be passed through the plurality of apertures from the front to the back, and from the back to the front, repeatedly. The deagglomerator may also include a plurality of blades that may aid in the deagglomeration of the cell masses. The deagglomerator may be configured between two syringes so that the tissue may be passed back and forth from the first syringe through the device to the second syringe, and then back again from the second syringe through the device and to the first syringe. In this way, the masses of cells may be properly deagglomerated.
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公开(公告)号：US20240226413A9
公开(公告)日：2024-07-11
申请号：US18277593
申请日：2022-02-17
CPC分类号： A61M1/895 , A61M1/67 , A61M1/815 , A61M5/3135 , A61M2202/08 , A61M2209/045 , A61M2209/06
摘要： According to an example aspect of the present invention, there is provided a sterile connector for fat harvesting, comprising a body configured to be at least partially inserted into a receptive syringe chamber. The body comprises an external interface end for facing the ambient space and an internal interface end for insertion into the syringe chamber. The connector further comprises a fat input conduit extending through the body. The fat input conduit comprises a coupling for a harvesting tube at the external interface end of the body and a feed port at the internal interface end of the body for feeding the harvested fat into the syringe chamber. The connecter further comprises an air output conduit extending through the body. The air output conduit comprises a coupling for a suction tube at the external interface end of the body and a suction port at the internal interface end of the body for providing a partial vacuum into the syringe chamber.
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公开(公告)号：US20240131247A1
公开(公告)日：2024-04-25
申请号：US18277593
申请日：2022-02-17
CPC分类号： A61M1/895 , A61M1/67 , A61M1/815 , A61M5/3135 , A61M2202/08 , A61M2209/045 , A61M2209/06
摘要： According to an example aspect of the present invention, there is provided a sterile connector for fat harvesting, comprising a body configured to be at least partially inserted into a receptive syringe chamber. The body comprises an external interface end for facing the ambient space and an internal interface end for insertion into the syringe chamber. The connector further comprises a fat input conduit extending through the body. The fat input conduit comprises a coupling for a harvesting tube at the external interface end of the body and a feed port at the internal interface end of the body for feeding the harvested fat into the syringe chamber. The connecter further comprises an air output conduit extending through the body. The air output conduit comprises a coupling for a suction tube at the external interface end of the body and a suction port at the internal interface end of the body for providing a partial vacuum into the syringe chamber.
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公开(公告)号：US20230225941A1
公开(公告)日：2023-07-20
申请号：US18010628
申请日：2021-06-18
申请人： BIOPSYBELL S.R.L.
CPC分类号： A61J1/14 , A61M1/895 , A61M1/69 , B01D29/27 , B01D29/56 , A61M2202/08 , A61M2205/75 , B01D2201/188 , B01D2201/605 , B01D2201/607
摘要： A flexible bag for the preparation of an adipose tissue graft provided with a proximal end and a distal end and comprising: a front wall and a rear wall, which are connected to one another to define a receiving space on the inside; a first filter arranged inside the bag to divide the receiving space into a first chamber and a second chamber and to micro-fragment the adipose tissue to obtain a micro-fragmented adipose tissue; and a second filter arranged inside the second chamber to obtain a third chamber and to obtain the graft by separating a waste material from the micro-fragmented adipose tissue. The first filter comprises a distal edge which is connected to the front wall between the proximal end and the distal end and the second filter comprises a proximal edge which is connected to the rear wall between the proximal end and the distal end.
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