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    Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body
    1.
    发明授权
    Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body 有权
    可聚合化合物，可聚合组合物，聚合物和光学各向异性体

    公开(公告)号：US09207360B2

    公开(公告)日：2015-12-08

    申请号：US14114073

    申请日：2012-04-27

    Applicant: Kei Sakamoto ,  Kumi Okuyama

    Inventor： Kei Sakamoto ,  Kumi Okuyama

    IPC: C07C251/82 ,  C07C251/86 ,  C07D277/82 ,  G02B1/08 ,  G02B5/30 ,  C07D215/38 ,  C07D237/34 ,  C07D263/58 ,  C08F220/34 ,  C08F222/10

    CPC classification number: C08F122/24 ,  C07C69/92 ,  C07C243/20 ,  C07C251/86 ,  C07D215/38 ,  C07D237/34 ,  C07D263/58 ,  C07D277/82 ,  C07D487/04 ,  C08F122/22 ,  C08F220/34 ,  C08F222/1006 ,  G02B1/08 ,  G02B5/3016 ,  G02B5/3083

    Abstract: The present invention relates to a polymerizable compound represented by a formula (I). The present invention provides a polymerizable compound, a polymerizable composition, a polymer, and an optically anisotropic article that are capable of obtaining an optical film having a low melting point, having excellent solubility, capable of being manufactured at low cost, and capable of uniform polarized light conversion across a broad wavelength region. [In formula: Y1 to Y6 are independently a chemical single bond, —O—, —O—C(═O)—, —C(═O)—O— etc.; G1 and G2 are independently a divalent C1-C20 aliphatic group etc.; Z1 and Z2 are independently C2-C10 alkenyl group that is substituted with a halogen atom etc.; Ax is a C2-C30 organic group that includes at least one aromatic ring selected from a group consisting of an aromatic hydrocarbon ring and an aromatic hetero ring; Ay is a hydrogen atom, a C1-C20 alkyl group, a C2-C20 alkenyl group, a C3-C12 cycloalkyl group etc.; A1 is a trivalent aromatic group etc.; A2 and A3 are independently a divalent C6-C30 aromatic group etc.; and Q1 is a hydrogen atom, or a C1-C6 alkyl group etc.]

    Abstract translation: 本发明涉及由式（I）表示的可聚合化合物。 本发明提供一种能够得到低熔点，溶解性优异的光学膜的聚合性化合物，聚合性组合物，聚合物和光学各向异性物品，能够以低成本制造，能够均匀 在宽波长区域的偏振光转换。 [式中，Y1〜Y6独立地为化学单键，-O - ， - O-C（= O） - ， - C（= O）-O-等）。 G1和G2独立地是二价C1-C20脂族基团等; Z 1和Z 2独立地为被卤素原子等取代的C 2 -C 10烯基; Ax是包含至少一个选自芳族烃环和芳族杂环的芳环的C 2 -C 30有机基团; Ay是氢原子，C1-C20烷基，C2-C20烯基，C3-C12环烷基等; A1是三价芳族基团等。 A2和A3独立地为二价C 6 -C 30芳族基团等; 并且Q 1是氢原子或C 1 -C 6烷基等]

    POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY
    7.
    发明申请
    POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY 有权
    可聚合化合物，聚合物，聚合物和光学异物体

    公开(公告)号：US20140142266A1

    公开(公告)日：2014-05-22

    申请号：US14114073

    申请日：2012-04-27

    Applicant: Kei Sakamoto ,  Kumi Okuyama

    Inventor： Kei Sakamoto ,  Kumi Okuyama

    IPC: G02B1/08

    CPC classification number: C08F122/24 ,  C07C69/92 ,  C07C243/20 ,  C07C251/86 ,  C07D215/38 ,  C07D237/34 ,  C07D263/58 ,  C07D277/82 ,  C07D487/04 ,  C08F122/22 ,  C08F220/34 ,  C08F222/1006 ,  G02B1/08 ,  G02B5/3016 ,  G02B5/3083

    Abstract: The present invention relates to a polymerizable compound represented by a formula (I). The present invention provides a polymerizable compound, a polymerizable composition, a polymer, and an optically anisotropic article that are capable of obtaining an optical film having a low melting point, having excellent solubility, capable of being manufactured at low cost, and capable of uniform polarized light conversion across a broad wavelength region. [In formula: Y1 to Y6 are independently a chemical single bond, —O—, —O—C(═O)—, —C(═O)—O— etc.; G1 and G2 are independently a divalent C1-C20 aliphatic group etc.; Z1 and Z2 are independently C2-C10 alkenyl group that is substituted with a halogen atom etc.; Ax is a C2-C30 organic group that includes at least one aromatic ring selected from a group consisting of an aromatic hydrocarbon ring and an aromatic hetero ring; Ay is a hydrogen atom, a C1-C20 alkyl group, a C2-C20 alkenyl group, a C3-C12 cycloalkyl group etc.; A1 is a trivalent aromatic group etc.; A2 and A3 are independently a divalent C6-C30 aromatic group etc.; and Q1 is a hydrogen atom, or a C1-C6 alkyl group etc.]

    Abstract translation: 本发明涉及由式（I）表示的可聚合化合物。 本发明提供一种能够得到低熔点，溶解性优异的光学膜的聚合性化合物，聚合性组合物，聚合物和光学各向异性物品，能够以低成本制造，能够均匀 在宽波长区域的偏振光转换。 [式中，Y1〜Y6独立地为化学单键，-O - ， - O-C（= O） - ， - C（= O）-O-等）。 G1和G2独立地是二价C1-C20脂族基团等; Z 1和Z 2独立地为被卤素原子等取代的C 2 -C 10烯基; Ax是包含至少一个选自芳族烃环和芳族杂环的芳环的C 2 -C 30有机基团; Ay是氢原子，C1-C20烷基，C2-C20烯基，C3-C12环烷基等; A1是三价芳族基团等。 A2和A3独立地为二价C 6 -C 30芳族基团等; 并且Q 1是氢原子或C 1 -C 6烷基等]

    Thrombopoietin mimetics
    8.
    发明授权
    Thrombopoietin mimetics 失效
    血小板生成素模拟物

    公开(公告)号：US07414040B2

    公开(公告)日：2008-08-19

    申请号：US10516988

    申请日：2003-06-06

    Applicant: Dirk A. Heerding

    Inventor： Dirk A. Heerding

    IPC: C07D231/20 ,  A61K31/655 ,  A61K31/415

    CPC classification number: C07D417/12 ,  C07C205/56 ,  C07C229/44 ,  C07C243/20 ,  C07C2601/08 ,  C07D231/20 ,  C07D231/46 ,  C07F9/65031

    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.

    Abstract translation: 发明的是非肽TPO模拟物。 还发明了用于制备本发明化合物的新方法和中间体。 还发明了一种在有需要的哺乳动物（包括人）中治疗血小板减少症的方法，其包括向所述哺乳动物施用有效量的选择的羟基-1-偶氮苯衍生物。

    Carbocyclic hydrazino inhibitors of copper-containing amine oxidases
    9.
    发明授权
    Carbocyclic hydrazino inhibitors of copper-containing amine oxidases 失效
    含铜胺氧化酶的碳环肼抑制剂

    公开(公告)号：US06982286B2

    公开(公告)日：2006-01-03

    申请号：US09902789

    申请日：2001-07-12

    Applicant: David John Smith ,  Ferenc Fülöp ,  Marjo Pihlavisto ,  László Lázár ,  Sakari Alaranta ,  Petri Vainio ,  Zsolt Szakonyi

    Inventor： David John Smith ,  Ferenc Fülöp ,  Marjo Pihlavisto ,  László Lázár ,  Sakari Alaranta ,  Petri Vainio ,  Zsolt Szakonyi

    IPC: A61K31/135

    CPC classification number: C07D273/00 ,  A61K31/15 ,  C07C243/20 ,  C07C2602/08

    Abstract: The present invention is directed to carbocyclic hydrazino compounds that function as inhibitors of copper-containing amine oxidases commonly known as semicarbazide-sensitive amine oxidases (SSAO), including the human SSAO known as Vascular Adhesion Protein-I (VAP-1). These SSAO inhibitors have therapeutic utility as drugs to treat conditions and diseases including, but not limited to, a number of inflammatory conditions and diseases (in particular chronic inflammatory conditions such as chronic arthritis, inflammatory bowel diseases, and chronic skin dermatoses), diseases related to carbohydrate metabolism and to aberrations in adipocyte differentiation or function and smooth muscle cell function, and vascular diseases. The novel compounds have the general formula: or a pharmaceutically acceptable solvate, hydrate, or salt thereof wherein R1 to R11 are as defined herein.

    Abstract translation: 本发明涉及用作通常称为氨基脲敏感性胺氧化酶（SSAO）的含铜胺氧化酶的抑制剂的碳环肼化合物，包括称为血管粘附蛋白-1（VAP-1）的人SSAO。 这些SSAO抑制剂具有用于治疗病症和疾病的药物的治疗用途，包括但不限于许多炎性病症和疾病（特别是慢性炎症病症如慢性关节炎，炎性肠病和慢性皮肤皮肤病），相关疾病 到碳水化合物代谢和脂肪细胞分化或功能和平滑肌细胞功能异常以及血管疾病。 新化合物具有以下通式：或其药学上可接受的溶剂合物，水合物或盐，其中R 1至R 11如本文所定义。

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