公开(公告)号：US20240279828A1

公开(公告)日：2024-08-22

申请号：US18565339

申请日：2022-05-31

申请人： GENSCRIPT USA INC. ,  CUSTOMARRAY, INC. ,  NANJING GENSCRIPT BIOTECH CO., LTD.

发明人： Feichi HU ,  Michael W. REED ,  John COOPER ,  Jackson KELLOCK ,  Cheng-Hsien WU

IPC分类号： C25B11/085 ,  B01J19/00 ,  C07C245/20 ,  C25B3/07 ,  C25B3/09 ,  C25B3/29 ,  C25B11/052 ,  C25B11/061 ,  C25B11/095 ,  C25D9/02 ,  C25F1/00

CPC分类号： C25B11/085 ,  B01J19/0046 ,  C07C245/20 ,  C25B3/07 ,  C25B3/09 ,  C25B3/29 ,  C25B11/052 ,  C25B11/061 ,  C25B11/095 ,  C25D9/02 ,  C25F1/00 ,  B01J2219/00596 ,  B01J2219/00713 ,  B01J2219/00722

摘要： Functionalized aryldiazonium salts and films formed by electrografting of functionalized aryldiazonium salts are provided. Methods for purifying functionalized aryldiazonium salts and for coating solid support systems with functionalized aryldiazonium salts are also provided. These coated solid support systems can be used, for example, in methods of oligonucleotide synthesis.

公开(公告)号：US11760709B2

公开(公告)日：2023-09-19

申请号：US17329650

申请日：2021-05-25

申请人： Inner Mongolia Sheng Tang International Mongolian Medicine Research Institute Co., Ltd.

发明人： Weidong Liu ,  Yantao Hao ,  Guodong Liang ,  Qinqin Gao ,  Pengshuai Li ,  Ting Zhang

IPC分类号： C07C37/045 ,  C07C245/20 ,  C07C37/05

CPC分类号： C07C37/045 ,  C07C37/05 ,  C07C245/20 ,  C07C2601/16 ,  C07C37/045 ,  C07C39/08

摘要： The present disclosure provides a method for preparing resorcinol through micro-channel reaction. In the method, resorcinol is prepared through micro-channel reaction using m-aminophenol as a raw material, a diazo salt is synthesized at 0° C. or more, hydrolysis of the diazo salt is performed at 90° C. or less, and then reaction conditions are reduced; the reaction time is decreased from traditional 10 hours to less than 2 minutes, and therefore the reaction time is significantly shortened; the purity of a product is 75% or more, which is significantly improved. The method provided by the present disclosure has high heat exchange efficiency and high mass transfer rate; the efficiency of reaction is improved by hundreds of times; the reaction system is precisely controlled in the temperature and pressure, and safe and reliable in process, and meanwhile is capable of stably controlling hazard processes such as diazotization, so as to promote safe industry production, reduce energy consumption and greatly reduce industrial hazard waste emission and realize green ecology development.

公开(公告)号：US20190233358A1

公开(公告)日：2019-08-01

申请号：US16374887

申请日：2019-04-04

申请人： UNIVERSITE LIBRE DE BRUXELLES (ULB) ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) ,  UNIVERSITE DE RENNES 1 ,  UNIVERSITE PARIS DESCARTES

发明人： Ivan JABIN ,  Alice MATTIUZZI ,  Corinne LAGROST ,  Philippe HAPIOT ,  Olivia REINAUD

IPC分类号： C07C43/21 ,  C08J7/04 ,  C07C43/225 ,  C07D333/50 ,  C07C217/94 ,  C07C205/37 ,  C07C69/736 ,  C07C59/72 ,  C07C245/20

CPC分类号： C07C43/21 ,  C07B2200/11 ,  C07C43/225 ,  C07C59/72 ,  C07C69/736 ,  C07C205/37 ,  C07C217/94 ,  C07C245/20 ,  C07C2603/90 ,  C07D333/50 ,  C08J7/04 ,  Y10T428/265

摘要： This invention relates to the direct grafting of a calixarene mostly onto the surface of a material, as well as to a grafting process, and certain calixarene intermediates useful for carrying the grafting process.

公开(公告)号：US09926263B2

公开(公告)日：2018-03-27

申请号：US15119746

申请日：2014-06-25

申请人： NANTONG TEXTILE & SILK INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

发明人： Jiajie Long ,  Xiaochen Wei ,  Ming Shen

IPC分类号： C07C245/20 ,  C07B43/00 ,  C09K3/00

CPC分类号： C07C245/20 ,  C07B43/00 ,  C09B29/0805 ,  C09B41/00 ,  C09K3/00

摘要： A solvent medium for diazotization reaction includes a mixed solution of polyethylene glycol and water. The molecular weight of polyethylene glycol is 200-600, and the volume ratio of polyethylene glycol and water is 1:0.4-1.5. The mixed solution also includes hydrochloric acid or sulfuric acid, and the concentration of H+ in the mixed solution is 0.32-1.72 mol L−1.

公开(公告)号：US20170342022A1

公开(公告)日：2017-11-30

申请号：US15619711

申请日：2017-06-12

申请人： Monsanto Technology LLC

发明人： Bruno De Kort ,  Matthew D. McReynolds ,  John J. Parlow ,  Rhonda S. Woerndle

IPC分类号： C07C245/20 ,  C07C51/09 ,  C07C37/045 ,  C07C209/36 ,  A01N37/40

CPC分类号： C07C245/20 ,  A01N37/40 ,  C07C37/045 ,  C07C51/09 ,  C07C209/365

摘要： The present disclosure relates, in general, to processes for converting 2,5-dichloroaniline compounds to the corresponding 2,5-dichlorobenzenediazonium compounds, and further relates to processes for the preparation of 2,5-dichlorophenol which is a key intermediate used in the manufacture of dicamba.

公开(公告)号：US20160318853A1

公开(公告)日：2016-11-03

申请号：US15106072

申请日：2014-12-17

申请人： MONSANTO TECHNOILGY LLC

发明人： Bruno De Kort ,  Matthew D. McReynolds ,  John J. Parlow ,  Rhonda S. Woerndle

IPC分类号： C07C245/20 ,  A01N37/40 ,  C07C51/09 ,  C07C37/045 ,  C07C209/36

CPC分类号： C07C245/20 ,  A01N37/40 ,  C07C37/045 ,  C07C51/09 ,  C07C209/365

摘要： The present disclosure relates, in general, to processes for converting 2,5-dichloroaniline compounds to the corresponding 2,5-dichlorobenzenediazonium compounds, and further relates to processes for the preparation of 2,5-dichlorophenol which is a key intermediate used in the manufacture of dicamba.

摘要翻译： 本公开一般涉及将2,5-二氯苯胺化合物转化为相应的2,5-二氯苯二氮化合物的方法，还涉及制备2,5-二氯苯酚的方法，其是用于 制造麦草畏

公开(公告)号：US09126905B2

公开(公告)日：2015-09-08

申请号：US14415265

申请日：2013-07-08

申请人： BASF SE

发明人： Michael Rack ,  Maximilian Dochnahl ,  Volker Maywald ,  Bernd Wolf ,  Joachim Gebhardt ,  Timo Frassetto ,  Uwe Josef Vogelbacher ,  Roland Götz

IPC分类号： C07C37/62 ,  C07C37/76 ,  C07C17/35 ,  C07C17/093 ,  C07C41/22 ,  C07C51/363 ,  C07C209/74 ,  C07D213/73

CPC分类号： C07C37/62 ,  C07C17/093 ,  C07C17/35 ,  C07C37/76 ,  C07C41/22 ,  C07C51/363 ,  C07C209/74 ,  C07C245/20 ,  C07D213/73 ,  C07C39/27

摘要： The present invention relates to a process for manufacturing fluoroaromatics of formula (I), A-F   (I) comprising step a) diazotization of aminoaromatics of formula (II) in anhydrous HF with an aqueous solution of a diazotizing agent; followed by step b) thermic decomposition of the diazonium salt of formula (III) resulting from step a); wherein the variables are defined according to the description.

摘要翻译： 本发明涉及一种制备式（I）的氟代芳族化合物的方法，A-F（I）包括步骤a）将式（II）的氨基芳族化合物在无水HF中的重氮化与重氮化剂的水溶液重氮化; 然后步骤b）由步骤a）得到的式（III）的重氮盐的热分解; 其中根据描述定义变量。

公开(公告)号：US08350097B2

公开(公告)日：2013-01-08

申请号：US13437802

申请日：2012-04-02

申请人： Thomas E. Jenkins

发明人： Thomas E. Jenkins

IPC分类号： C07C39/24 ,  C07C39/06 ,  C07C261/00 ,  A61K31/05

CPC分类号： C07C39/06 ,  A61K9/0019 ,  C07B2200/07 ,  C07C37/003 ,  C07C37/045 ,  C07C37/055 ,  C07C37/86 ,  C07C39/27 ,  C07C245/20 ,  C07C271/44 ,  C07C39/19

摘要： A (−)-stereoisomer of formula (I): (formula I), wherein X is H or F; or a pharmaceutically acceptable salt or pro drug thereof, is useful as an anesthetic.

摘要翻译： 式（I）的（ - ） - 立体异构体：（式I），其中X是H或F; 或其药学上可接受的盐或其前药可用作麻醉剂。

公开(公告)号：US07892517B2

公开(公告)日：2011-02-22

申请号：US11840433

申请日：2007-08-17

申请人： James M. Tour ,  Jeffrey L. Bahr ,  Jiping Yang

发明人： James M. Tour ,  Jeffrey L. Bahr ,  Jiping Yang

IPC分类号： D01F9/12

CPC分类号： B82Y30/00 ,  B82Y40/00 ,  C01B32/174 ,  C01B2202/02 ,  C01B2202/06 ,  C01B2202/36 ,  C01P2002/72 ,  C01P2002/82 ,  C01P2002/84 ,  C01P2002/88 ,  C01P2004/04 ,  C01P2004/13 ,  C07C245/20 ,  C07C321/26 ,  C07C321/28 ,  C08K9/04 ,  C09C1/48 ,  C09C1/56 ,  C09C1/565 ,  H01G11/36 ,  Y02E60/13 ,  Y10S977/788 ,  Y10S977/847 ,  Y10T428/13 ,  Y10T428/30

摘要： Methods for the chemical modification of carbon nanotubes involve the derivatization of multi- and single-wall carbon nanotubes, including small diameter (ca. 0.7 nm) single-wall carbon nanotubes, with diazonium species. The method allows the chemical attachment of a variety of organic compounds to the side and ends of carbon nanotubes. These chemically modified nanotubes have applications in polymer composite materials, molecular electronic applications, and sensor devices. The methods of derivatization include electrochemical induced reactions, thermally induced reactions, and photochemically induced reactions. Moreover, when modified with suitable chemical groups, the derivatized nanotubes are chemically compatible with a polymer matrix, allowing transfer of the properties of the nanotubes (such as, mechanical strength or electrical conductivity) to the properties of the composite material as a whole. Furthermore, when modified with suitable chemical groups, the groups can be polymerized to form a polymer that includes carbon nanotubes.

摘要翻译： 用于碳纳米管的化学修饰的方法涉及包括小直径（约0.7nm）单壁碳纳米管与重氮物质的多壁和单壁碳纳米管的衍生化。 该方法允许将各种有机化合物化学连接到碳纳米管的侧面和末端。 这些化学改性的纳米管可用于聚合物复合材料，分子电子应用和传感器装置。 衍生化的方法包括电化学诱导反应，热诱导反应和光化学诱导反应。 此外，当用合适的化学基团改性时，衍生的纳米管与聚合物基质化学相容，允许将纳米管的性质（例如机械强度或电导率）转移到复合材料的整体性能上。 此外，当用合适的化学基团改性时，基团可以聚合形成包括碳纳米管的聚合物。

公开(公告)号：US20100041876A1

公开(公告)日：2010-02-18

申请号：US12513965

申请日：2007-11-07

申请人： Bernd Schmidt ,  Frank Holter

发明人： Bernd Schmidt ,  Frank Holter

IPC分类号： C07C245/20

CPC分类号： C07C245/20

摘要： A process is described for preparing aromatic diazonium salts, wherein the starting compound is an aromatic amide and the amide bond is first split hydrolytically and the amine compound thus obtained is diazotized with an inorganic nitrite salt. The diazonium salts thus obtained can be converted to stable salts and then serve as starting materials for further reactions, such as the Heck reaction.

摘要翻译： 描述了用于制备芳族重氮盐的方法，其中起始化合物是芳族酰胺，并且酰胺键首先被水解裂解，并且由此获得的胺化合物用无机亚硝酸盐进行重氮化。 由此获得的重氮盐可以转化成稳定的盐，然后作为进一步反应的起始物质，如Heck反应。