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    2-indanmethanol derivatives and their use in perfumery
    2.
    发明授权
    2-indanmethanol derivatives and their use in perfumery 有权
    2-茚满甲醇衍生物及其在香料中的应用

    公开(公告)号：US06323173B1

    公开(公告)日：2001-11-27

    申请号：US09478507

    申请日：2000-01-06

    Applicant: Beat Winter ,  Philippe Schneider

    Inventor： Beat Winter ,  Philippe Schneider

    IPC: A61K746

    CPC classification number: C11B9/0049 ,  C07C33/34 ,  C07C45/75 ,  C07C49/252

    Abstract: The compounds of the formula wherein the symbols R1, R2, R3 and R4 represent, independently of one another, a hydrogen atom or a linear or branched, saturated or unsaturated C1 to C3 lower alkyl radical, are advantageous as perfuming ingredients for the preparation of perfuming compositions and perfumed articles, to which they impart odoriferous notes of the lily of the valley type.

    Abstract translation: 符号R 1，R 2，R 3和R 4中的取代基的化合物彼此独立地表示氢原子或直链或支链，饱和或不饱和的C1至C3低级烷基，作为加香成分用于制备加香 组合物和香料制品，它们赋予谷类百合的气味。

    4-Biphenylyl-4-hydroxyalkan-2-ones
    7.
    发明授权
    4-Biphenylyl-4-hydroxyalkan-2-ones 失效
    4-联苯基-4-羟基烷基-2-酮

    公开(公告)号：US4228105A

    公开(公告)日：1980-10-14

    申请号：US964046

    申请日：1978-11-27

    Applicant: Rudiger Jeck

    Inventor： Rudiger Jeck

    IPC: C07D295/10 ,  C07C45/00 ,  C07C45/51 ,  C07C45/66 ,  C07C49/20 ,  C07C49/223 ,  C07C49/225 ,  C07C49/235 ,  C07C49/24 ,  C07C49/252 ,  C07C67/00 ,  C07C213/00 ,  C07C225/22 ,  C07C241/00 ,  C07C251/16 ,  C07D295/112 ,  C07C49/82

    CPC classification number: C07D295/112 ,  C07C45/516 ,  C07C45/66 ,  C07C49/223 ,  C07C49/225 ,  C07C49/235 ,  C07C49/252

    Abstract: A process for the production of compounds of formula I, ##STR1## wherein R.sub.1 is alkyl of 1 to 3 carbon atoms,R.sub.2 is hydrogen, fluorine, chlorine or bromine, andR.sub.3 is bromine, iodine, isobutyl, tert. butyl, cyclohexyl, cyclohexenyl; or phenyl, optionally substituted by fluorine, chlorine, bromine or alkoxy of 1 to 4 carbon atoms; or a radical of formula II, ##STR2## in which either R.sub.4 and R.sub.5 are the same or different and each signifies alkyl of 1 to 3 carbon atoms, orR.sub.4 and R.sub.5 together signify the radical --(CH.sub.2).sub.n --, in which n is 4 or 5, the radical --CH.sub.2 --CH.sub.2 --0--CH.sub.2 --CH.sub.2 --, the radical --CH.sub.2 --CH.dbd.CH--CH.sub.2 --, or the radical --CH.sub.2 --CH.sub.2 --N(R.sub.6)--CH.sub.2 --CH.sub.2 --, in which R.sub.6 is hydrogen or alkyl of 1 to 3 carbon atoms. Hydroxyketone and hydroxy imine intermediates are also disclosed.The compounds of formula I are known to exhibit anti-inflammatory activity.

    Abstract translation: 制备式I化合物的方法，其中R 1为1至3个碳原子的烷基，R 2为氢，氟，氯或溴，R 3为溴，碘，异丁基，叔丁基。 丁基，环己基，环己烯基; 或苯基，任选被氟，氯，溴或具有1至4个碳原子的烷氧基取代; 或式II的基团，其中R 4和R 5相同或不同，并且各自表示1至3个碳原子的烷基，或者R 4和R 5一起表示基团 - （CH 2）n - ，其中 基团-CH 2 -CH 2 -O-CH 2 -CH 2 - ，基团-CH 2 -CH = CH-CH 2 - 或基团-CH 2 -CH 2 -N（R 6）-CH 2 -CH 2 - 其中R 6是氢或1至3个碳原子的烷基。 还公开了羟基酮和羟基亚胺中间体。 已知式I化合物具有抗炎活性。

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