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公开(公告)号：US20120302675A1
公开(公告)日：2012-11-29
申请号：US13575853
申请日：2011-01-28
IPC分类号： C07D279/34 , C08L19/00 , C08L13/00 , C08K5/46 , C08K5/3417
CPC分类号： C08K5/46 , C07D209/88 , C07D279/34 , C08K5/3417
摘要： A condensed heterocyclic compound which is shown by the following formula (I) and a composition containing an (a) organic material and (b) at least one type of the condensed heterocyclic compound are provided. (Y indicates a chemical single bond, —S(═O)—, or —SO2—. Ra and Rb indicate substitutable C1 to C30 organic groups. Za and Zb indicate chemical single bonds or —SO2—. X1 and X2 indicate hydrogen atoms etc. n and m respectively independently indicate integers of 0 to 2, where one of n and m is not 0).
摘要翻译： 提供由下式（I）表示的稠合杂环化合物和含有（a）有机材料和（b）至少一种类型的稠合杂环化合物的组合物。 （Y表示化学单键，-S（= O） - 或-SO 2 - ，R a和R b表示可取代的C 1至C 30有机基团，Za和Zb表示化学单键或-SO 2 - ，X 1和X 2表示氢原子 n和m分别独立地表示0〜2的整数，其中n和m中的一个不为0）。
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2.发明申请Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds 有权吩噻嗪，S-氧化物和S，S-二氧化物以及苯并恶嗪作为Oleds的发射体公开(公告)号：US20100308714A1
公开(公告)日：2010-12-09
申请号：US11720274
申请日：2005-11-25
IPC分类号： H01L51/00 , C07D279/18 , H01J1/62 , C07D417/02
CPC分类号： C09K11/06 , C07D279/26 , C07D279/28 , C07D279/34 , C07D417/04 , C07D417/10 , C09B19/00 , C09B21/00 , C09B23/141 , C09B23/145 , C09K2211/1033 , C09K2211/1037 , C09K2211/1044 , C09K2211/185 , H01L51/005 , H01L51/0052 , H01L51/0059 , H01L51/0072 , H01L51/0085 , H01L51/5012 , H01L51/5096 , H01L2251/308 , H05B33/14 , Y10S428/917
摘要： The use of phenoxazine, phenothiazine, phenothiazine S-oxide or phenothiazine S,S-dioxide derivatives as emitter substances in organic light-emitting diodes, an organic light-emitting diode comprising a light-emitting layer, the light-emitting layer comprising at least one phenoxazine, phenothiazine, phenothiazine S-oxide or phenothiazine S,S-dioxide derivative as an emitter substance, and a light-emitting layer comprising or consisting of the aforementioned phenoxazine, phenothiazine-phenothiazine, phenothiazine S-oxide or phenothiazine S,S-dioxide derivative as an emitter substance, a hole- and exciton-blocking layer comprising or consisting of the aforementioned phenoxazine derivative, phenothiazine derivative, phenothiazine S-oxide derivative or phenothiazine S,S-dioxide derivative, and a device which comprises an inventive organic light-emitting diode. The present invention further relates to specific phenothiazine S,S-dioxide derivatives, phenothiazine S-oxide derivatives and phenothiazine derivatives and production processes thereof, and to their use in organic light-emitting diodes.
摘要翻译： 在有机发光二极管中使用吩恶嗪，吩噻嗪，吩噻嗪S-氧化物或吩噻嗪S，S-二氧化物衍生物作为发射物质，包含发光层的有机发光二极管，至少包含发光层 一种吩恶嗪，吩噻嗪，吩噻嗪S-氧化物或吩噻嗪S，S-二氧化物衍生物作为发射体物质，以及由上述吩恶嗪，吩噻嗪 - 吩噻嗪，吩噻嗪S-氧化物或吩噻嗪S组成或组成的发光层，S- 作为发射体物质的二氧化物衍生物，包含前述吩恶嗪衍生物，吩噻嗪衍生物，吩噻嗪S-氧化物衍生物或吩噻嗪S，S-二氧化物衍生物或包含本发明有机光的器件的空穴 - 和激子阻断层 发光二极管。 本发明还涉及特定的吩噻嗪S，S-二氧化物衍生物，吩噻嗪S-氧化物衍生物和吩噻嗪衍生物及其制备方法，以及它们在有机发光二极管中的应用。
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3.发明申请公开(公告)号：US20020115657A1
公开(公告)日：2002-08-22
申请号：US10076575
申请日：2002-02-08
发明人： Lone Jeppesen , Paul Stanley Bury , Per Sauerberg
IPC分类号： A61K031/55 , A61K031/5415 , A61K031/538 , A61K031/498 , A61K031/473
CPC分类号： C07D471/04 , C07D209/86 , C07D209/88 , C07D223/22 , C07D273/06 , C07D279/34
摘要： The present invention relates to compounds of the general formula (I) 1 The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
摘要翻译： 本发明涉及通式（I）的化合物。该化合物可用于治疗和/或预防由核受体介导的病症，特别是过氧化物酶体增殖物激活受体（PPAR）
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公开(公告)号：US4859667A
公开(公告)日：1989-08-22
申请号：US3354
申请日：1987-01-14
申请人： Cheuk K. Lau , Christiane Yoakim , Joshua Rokach , Rejean Fortin , Yvan Guindon
发明人： Cheuk K. Lau , Christiane Yoakim , Joshua Rokach , Rejean Fortin , Yvan Guindon
IPC分类号： A61K31/495 , A61K31/535 , A61K31/54 , C07C46/06 , C07D241/46 , C07D265/34 , C07D265/38 , C07D279/18 , C07D279/34 , C07D279/36 , C07D293/10
CPC分类号： C07D293/10 , A61K31/495 , A61K31/535 , A61K31/54 , C07C46/06 , C07D241/46 , C07D265/34 , C07D265/38 , C07D279/18 , C07D279/34 , C07D279/36
摘要： Phenothiazone derivatives and analogs thereof, pharmaceutical compositions and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders and inflammation.
摘要翻译： 苯并噻唑衍生物及其类似物，药物组合物和治疗方法。 这些化合物可用作哺乳动物白细胞三烯生物合成的抑制剂。 因此，这些化合物是治疗过敏性疾病，哮喘，心血管疾病和炎症的有用的治疗剂。
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公开(公告)号：US4845083A
公开(公告)日：1989-07-04
申请号：US1946
申请日：1987-01-09
申请人： Rejean Fortin , Cheuk K. Lau , Yvan Guindon , Joshua Rokach , Christiane Yoakim
发明人： Rejean Fortin , Cheuk K. Lau , Yvan Guindon , Joshua Rokach , Christiane Yoakim
IPC分类号： C07D265/38 , C07D279/20 , C07D279/22 , C07D279/30 , C07D279/34 , C07D293/10
CPC分类号： C07D279/34 , C07D265/38 , C07D279/20 , C07D279/22 , C07D279/30 , C07D293/10
摘要： Phenothiazine derivatives and analogs thereof having the Formula I are useful as inhibitors of the biosynthesis of mammalian leukotrienes. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders and inflammation, and are useful as cytoprotective agents. ##STR1##
摘要翻译： 具有式I的吩噻嗪衍生物及其类似物可用作哺乳动物白三烯生物合成的抑制剂。 因此，这些化合物是用于治疗过敏性疾病，哮喘，心血管疾病和炎症的有用的治疗剂，并且可用作细胞保护剂。
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6.发明授权Phenothiazine and derivatives and analogs and use as leukotriene biosynthesis inhibitors 失效吩噻嗪及其衍生物和类似物，并用作白三烯生物合成抑制剂
公开(公告)号：US4666907A
公开(公告)日：1987-05-19
申请号：US654991
申请日：1986-09-26
申请人： Rejean Fortin , Cheuk K. Lau , Yvan Guindon , Joshua Rokach , Christiane Yoakim
发明人： Rejean Fortin , Cheuk K. Lau , Yvan Guindon , Joshua Rokach , Christiane Yoakim
IPC分类号： C07D265/38 , C07D279/20 , C07D279/22 , C07D279/30 , C07D279/34 , C07D293/10 , A61K31/535 , A61K31/54
CPC分类号： C07D265/38 , C07D279/20 , C07D279/22 , C07D279/30 , C07D279/34 , C07D293/10
摘要： Phenothiazine derivatives and analogs thereof having the Formula I are useful as inhibitors of the biosynthesis of mammalian leukotrienes. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders and inflammation, and are useful as cytoprotective agents. ##STR1##
摘要翻译： 具有式I的吩噻嗪衍生物及其类似物可用作哺乳动物白三烯生物合成的抑制剂。 因此，这些化合物是用于治疗过敏性疾病，哮喘，心血管疾病和炎症的有用的治疗剂，并且可用作细胞保护剂。
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公开(公告)号：US20180198075A1
公开(公告)日：2018-07-12
申请号：US15740044
申请日：2016-07-04
申请人： CYNORA GMBH
发明人： Michael Danz , Daniel Zink
IPC分类号： H01L51/00 , C07D209/88 , C09K11/06 , C07D219/14 , C07D265/38 , C07D209/86 , C07D403/04 , C07D409/10 , C07D409/14 , C07D279/26 , C07F7/08 , C07D279/34 , C07D215/06 , C07D241/48 , C07D417/14
CPC分类号： H01L51/0072 , C07D209/08 , C07D209/56 , C07D209/80 , C07D209/82 , C07D209/86 , C07D209/88 , C07D215/06 , C07D219/08 , C07D219/14 , C07D241/48 , C07D265/38 , C07D279/02 , C07D279/22 , C07D279/26 , C07D279/34 , C07D403/04 , C07D409/10 , C07D409/14 , C07D417/10 , C07D417/14 , C07D487/04 , C07F7/0816 , C09K11/06 , C09K2211/1018 , H01L51/0003 , H01L51/001 , H01L51/0052 , H01L51/0061 , H01L51/0068 , H01L51/0071 , H01L51/0094 , H01L51/5004 , H01L51/5012 , H01L51/5024 , H01L51/5072 , H01L51/5088 , H01L51/5096 , H01L2251/552 , Y02E10/549 , Y02P70/521
摘要： The invention relates to an organic molecule having a structure of the formula I where X=CN or CF3; D=chemical unit having a structure of the formula I-1: where #=attachment point of the unit of formula I-1 to the central phenyl ring in the structure of formula I; A and B=independently of one another selected from the group consisting of CRR1, CR, NR, N, there being a single or double bond between A and B and a single or double bond between B and Z; Z=a direct bond or a divalent organic bridge which is a substituted or unsubstituted C1-C9-alkylene, C2-C8-alkenylene, C2-C8-alkynylene or arylene group or a combination thereof, —CRR1, —C═CRR1, —C═NR, —NR—, —O—, —SiRR1—, —S—, —S(O)—, —S(O)2—, O-interrupted substituted or unsubstituted C1-C9-alkylene, C2-C8-alkenylene, C2-C8-alkynylene or arylene group, phenyl units or substituted phenyl units.
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8.发明授权2-spiro-substituted iminothiazines and their mono-and dioxides as bace inhibitors, compositions and their use 有权2-螺取代的亚氨基噻嗪及其单和二氧化物作为抑制剂，组合物及其用途公开(公告)号：US09181236B2
公开(公告)日：2015-11-10
申请号：US14240215
申请日：2012-08-21
申请人： Wen-Lian Wu , Duane A. Burnett , Andrew W. Stamford , Jared N. Cumming , Theodros Asberom , Chad Bennett , Thavalakulamgara K. Sasiskumar , Jack D. Scott
发明人： Wen-Lian Wu , Duane A. Burnett , Andrew W. Stamford , Jared N. Cumming , Theodros Asberom , Chad Bennett , Thavalakulamgara K. Sasiskumar , Jack D. Scott
IPC分类号： C07D417/14 , C07D417/12 , C07D513/04 , C07D513/10 , A61K45/06 , C07D417/04 , C07D417/10 , C07D279/34 , C07D519/00
CPC分类号： C07D417/14 , A61K45/06 , C07D279/34 , C07D417/04 , C07D417/10 , C07D417/12 , C07D513/04 , C07D513/10 , C07D519/00
摘要： In its many embodiments, the present invention provides certain iminothiazine dioxide compounds, including compounds Formula (I): and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomeros and said stereoisomers, wherein each of the variables shown in the formula are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including Alzheimer's disease, are also disclosed.
摘要翻译： 在其许多实施方案中，本发明提供了某些亚氨基噻嗪二氧化物化合物，包括式（I）化合物及其互变异构体和立体异构体，以及所述化合物，所述互变异构体和所述立体异构体的药学上可接受的盐，其中式 如本文所定义。 本发明的新化合物可用作BACE抑制剂和/或用于治疗和预防与其相关的各种病症。 还公开了包含一种或多种这样的化合物（单独和与一种或多种其它活性剂组合）的药物组合物及其制备和使用方法，包括阿尔茨海默氏病。
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公开(公告)号：US20150087754A1
公开(公告)日：2015-03-26
申请号：US14560911
申请日：2014-12-04
申请人： ZEON CORPORATION
IPC分类号： C08K5/46 , C07D209/88 , C08K5/3417 , C07D279/34
CPC分类号： C08K5/46 , C07D209/88 , C07D279/34 , C08K5/3417
摘要： A condensed heterocyclic compound which is shown by the following formula (I) and a composition containing an (a) organic material and (b) at least one type of the condensed heterocyclic compound are provided. (Y indicates a chemical single bond, —S(═O)—, or —SO2—. Ra and Rb indicate substitutable C1 to C30 organic groups. Za and Zb indicate chemical single bonds or —SO2—. X1 and X2 indicate hydrogen atoms etc. n and m respectively independently indicate integers of 0 to 2, where one of n and m is not 0).
摘要翻译： 提供由下式（I）表示的稠合杂环化合物和含有（a）有机材料和（b）至少一种类型的稠合杂环化合物的组合物。 （Y表示化学单键，-S（= O） - 或-SO 2 - ，R a和R b表示可取代的C 1至C 30有机基团，Za和Zb表示化学单键或-SO 2 - ，X 1和X 2表示氢原子 n和m分别独立地表示0〜2的整数，其中n和m中的一个不为0）。
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公开(公告)号：US08937121B2
公开(公告)日：2015-01-20
申请号：US13575853
申请日：2011-01-28
IPC分类号： C08K5/46 , C08K5/3417 , C08L13/00 , C08L19/00 , C07D279/34 , C07D209/88
CPC分类号： C08K5/46 , C07D209/88 , C07D279/34 , C08K5/3417
摘要： A condensed heterocyclic compound which is shown by the following formula (I) and a composition containing an (a) organic material and (b) at least one type of the condensed heterocyclic compound are provided. (Y indicates a chemical single bond, —S(═O)—, or —SO2—. Ra and Rb indicate substitutable C1 to C30 organic groups. Za and Zb indicate chemical single bonds or —SO2—. X1 and X2 indicate hydrogen atoms etc. n and m respectively independently indicate integers of 0 to 2, where one of n and m is not 0).
摘要翻译： 提供由下式（I）表示的稠合杂环化合物和含有（a）有机材料和（b）至少一种类型的稠合杂环化合物的组合物。 （Y表示化学单键，-S（= O） - 或-SO 2 - ，R a和R b表示可取代的C 1至C 30有机基团，Za和Zb表示化学单键或-SO 2 - ，X 1和X 2表示氢原子 n和m分别独立地表示0〜2的整数，其中n和m中的一个不为0）。
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