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公开(公告)号:US20240018112A1
公开(公告)日:2024-01-18
申请号:US18247662
申请日:2021-09-29
发明人: Carla Recker , Andreas Jacob , David-Raphael Dauer , Julian Strohmeier , Anna-Lena Dreier , Jörg-August Becker , Florian Matz , Rebecca Graf , Jan Flormann
IPC分类号: C07D279/20 , C09B21/00 , C10L1/24 , C09K15/30 , C08K5/46 , C09D7/41 , C10M135/36 , B60C1/00
CPC分类号: C07D279/20 , C09B21/00 , C10L1/2456 , C09K15/30 , C08K5/46 , C09D7/41 , C10M135/36 , B60C1/0016 , B60C1/0025 , C10M2219/108 , C10N2040/25
摘要: The invention relates to a compound, to a rubber mixture containing the compound, to a vehicle tire comprising the rubber mixture in at least one component, to a process for producing the compound and to the use of the compound as an aging stabilizer and/or antioxidant and/or antiozonant and/or dye.
The compound according to the invention has the formula I).-
公开(公告)号:US11344558B2
公开(公告)日:2022-05-31
申请号:US14929111
申请日:2015-10-30
发明人: Claude Michel Wischik , Janet Elizabeth Rickard , Charles Robert Harrington , David Horsley , John Mervyn David Storey , Colin Marshall , James Peter Sinclair , Thomas Craven Baddeley
IPC分类号: A61K31/5415 , C07D279/22 , C07D279/20 , C09B21/00
摘要: Described are methods of preparing reduced 3,7-diamino-10H-phenothiazine (DAPTZ) compounds of formula: wherein: R1 and R9 are independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R3NA and R3NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R7NA and R7NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of HX1 and HX2 is independently a protic acid; and pharmaceutically acceptable salts, solvates, and hydrates thereof. These methods are particularly useful for producing stable reduced forms, and with high purity. The stability and purity are especially relevant for pharmaceutical compositions for the treatment of disease. The compounds are useful for treatment of e.g. tauopathies, such as Alzheimer's disease, and also as prodrugs for the corresponding oxidized thioninium drugs.
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公开(公告)号:US20220081404A1
公开(公告)日:2022-03-17
申请号:US17243005
申请日:2021-04-28
IPC分类号: C07D279/20 , C07D279/18 , C07D417/04 , C07D417/14
摘要: The present disclosure provides phenothiazine derivative compounds and salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
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公开(公告)号:USRE48859E1
公开(公告)日:2021-12-21
申请号:US16592326
申请日:2019-10-03
发明人: Thomas F. Guarr , Matthew M. Gregory , Nicholas Robert Boersma , Robert Andrew Polik , Nicholas Mortimer
IPC分类号: H01M10/42 , C07D209/86 , C07D209/88 , C07D241/46 , C07D279/20 , C07D279/22 , C07D279/26 , H01M10/0525 , H01M10/0567 , H01M10/0569
摘要: A rechargeable lithium-ion cell has a cell capacity and includes a positive electrode having a recharged potential and a negative electrode. The rechargeable lithium-ion cell also includes a charge-carrying electrolyte. The charge-carrying electrolyte includes a charge-carrying medium and a lithium salt. The rechargeable lithium-ion cell also includes a redox shuttle having the following structure.
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公开(公告)号:US10854911B2
公开(公告)日:2020-12-01
申请号:US15654464
申请日:2017-07-19
发明人: Susan A. Odom , Chad Risko , Matthew D. Casselman , Corrine F. Elliott , N. Harsha Attanayake , Subrahmanyam Modekrutti
IPC分类号: H01M10/056 , C07D279/22 , C07D279/20 , H01M10/0525 , H01M4/133 , H01M4/131 , H01M8/18 , H01M10/0567 , H01M4/02 , H01M4/587
摘要: Compounds for use in a rechargeable battery are provided, including a compound according to the formula: wherein R1 and R9 are independently selected from the group consisting of H, alkyl, aryl, perfluoroaryl, perfluoroalkyl, alkylaryl, alkoxyaryl, alkylcarboxyl, aryl carbonyl, haloalkyl, perfluoroalkyl, glycols, haloaryl, a negative electrolyte, and a polymer, so long as when R1 is H, R9 is not H; and R10 is selected from the group consisting of methyl, alkyl, aryl, alkylaryl, alkoxyaryl, alkylcarboxyl, aryl carbonyl, haloalkyl, perfluoroalkyl, perfluoroaryl, glycols, haloaryl, an oligomer, and a polymer.
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公开(公告)号:US10809617B2
公开(公告)日:2020-10-20
申请号:US16251622
申请日:2019-01-18
发明人: Jun Hatakeyama , Masaki Ohashi
IPC分类号: G03F7/038 , C07C65/05 , C07C309/65 , G03F7/039 , C07C57/58 , C07C63/70 , C07C65/03 , C07C233/54 , C07C271/28 , C07C309/66 , C07C381/12 , C07D279/20 , C07D327/08 , C07D333/76 , G03F7/004 , G03F7/16 , G03F7/20 , G03F7/32 , G03F7/38
摘要: A resist composition comprising a base polymer and a sulfonium salt of iodized benzoic acid offers a high sensitivity and minimal LWR independent of whether it is of positive or negative tone.
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公开(公告)号:US20190169519A1
公开(公告)日:2019-06-06
申请号:US16211480
申请日:2018-12-06
发明人: Abhimanyu O. PATIL , Satish BODIGE , Kyle LEWIS
IPC分类号: C10M105/72 , C07D279/20
摘要: A composition that includes one or more compounds represented by the formula wherein R1 and R2 are same or different and are the residue of an alkyl group having more than 10 carbon atoms wherein the composition has a viscosity (Kv100) from 2 to 300 at 100° C. as determined by ASTM D-445, and a viscosity index (VI) from −100 to 300 as determined by ASTM D-2270. The disclosure also relates to a process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method for improving oxidative stability of a lubricating oil by using as the lubricating oil a formulated oil containing the composition.
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8.
公开(公告)号:US10195602B2
公开(公告)日:2019-02-05
申请号:US15366991
申请日:2016-12-01
摘要: A photocatalytic system having enhanced photo efficiency/photonic efficacy is provided that includes a thin nucleation material coated on a substrate. The nucleation material enhances lattice matching for a subsequently deposited photocatalytic active material. Such a photocatalytic system may be used as a self-cleaning surface in an application where removal of fingerprints and other residue is desired. In certain aspects, the nucleation material comprises aluminum oxide (Al2O3) and the photocatalytic material comprises an anatase phase of titanium dioxide (TiO2) deposited over the nucleation material. A photocatalytic activity of the system is ≥ about 50% above a comparative photocatalytic activity where the photocatalytic active material is disposed directly on the substrate. Methods of making such photocatalytic systems are also provided.
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公开(公告)号:US20180226586A1
公开(公告)日:2018-08-09
申请号:US15746228
申请日:2016-07-01
申请人: Merck Patent GmbH
IPC分类号: H01L51/00 , C07D209/86 , C07D209/88 , C07D471/04 , C07F5/02 , C07D219/02 , C07D219/04 , C07F7/08 , C07D241/48 , C07D265/38 , C07D279/20 , C07D209/80 , C08G61/12 , C08G73/06
CPC分类号: H01L51/0072 , C07D209/80 , C07D209/86 , C07D209/88 , C07D219/02 , C07D219/04 , C07D241/48 , C07D265/38 , C07D279/20 , C07D471/04 , C07F5/027 , C07F7/0816 , C08G61/124 , C08G73/0672 , C08G2261/11 , C08G2261/12 , C08G2261/132 , C08G2261/226 , C08G2261/228 , C08G2261/3142 , C08G2261/3241 , C08G2261/3245 , C08G2261/3246 , C08G2261/3247 , C08G2261/364 , C08G2261/41 , C08G2261/411 , C08G2261/412 , C08G2261/414 , C08G2261/514 , C08G2261/95 , H01L51/0002 , H01L51/0035 , H01L51/0036 , H01L51/0039 , H01L51/0043 , H01L51/0071 , H01L51/008 , H01L51/0094 , H01L51/5012 , H01L51/5072 , H01L51/5088 , H01L51/5096
摘要: The present invention relates to a phenyl-derivative compound substituted with at least two electron acceptors and at least two electron donors. Formula (I) RAaRDbRScC6 wherein a is 2, 3 or 4; b is 2, 3 or 4; c is 0, 1 or 2; a+b−c=6; RA is at each occurrence independently a group with −M-effect; RB is at each occurrence independently a group with +−M-effect; RS is as defined in claim 1. Said compound is suited for use in organic electronic devices, particularly in organic electroluminescent devices.
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公开(公告)号:US20180208565A1
公开(公告)日:2018-07-26
申请号:US15746338
申请日:2016-07-20
发明人: John Mervyn David STOREY , Christopher Paul LARCH , Steven John KEMP , Scott CLUNAS , Sarah Louise NICOLL , Helen Sarah GIBBARD , Michael SIMPSON , James Peter SINCLAIR , Colin MARSHALL
IPC分类号: C07D279/20
CPC分类号: C07D279/20
摘要: The present invention pertains generally to the field of chemical synthesis, and more particularly to methods of chemical synthesis which include the step of preparing a substituted 10H-phenothiazine-3,7-diamine compound of Formula (1) by a step of selective alkylation by reductive amination, in which the corresponding unsubstituted diamine of Formula (4) is reacted with aldehyde/ketone, under reductive amination conditions. The present invention also relates to such methods which incorporate additional subsequent and/or preceding steps, for example, to prepare compounds of Formulae (2) and (3) from compounds of Formula (1), and to prepare compounds of Formula (4) from, for example, compounds of Formulae (5), (6), (7), (8), and (9). Compounds of Formula (1), Formula (2), and Formula (3) are useful, for example, in the treatment of diseases of protein aggregation, such as Alzheimer's disease.
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