公开(公告)号：US11951110B2

公开(公告)日：2024-04-09

申请号：US17591306

申请日：2022-02-02

Applicant: WisTa Laboratories Ltd.

Inventor： Claude Michel Wischik ,  Janet Elizabeth Rickard ,  Charles Robert Harrington ,  David Horsley ,  John Mervyn David Storey ,  Colin Marshall ,  James Peter Sinclair ,  Thomas Craven Baddeley

IPC: A61K31/5415 ,  C07D279/20 ,  C07D279/22 ,  C09B21/00

CPC classification number: A61K31/5415 ,  C07D279/20 ,  C07D279/22 ,  C09B21/00 ,  Y02A50/30

Abstract: Described are methods of preparing reduced 3,7-diamino-10H-phenothiazine (DAPTZ) compounds of formula:




wherein: R1 and R9 are independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R3NA and R3NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R7NA and R7NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of HX1 and HX2 is independently a protic acid; and pharmaceutically acceptable salts, solvates, and hydrates thereof. These methods are particularly useful for producing stable reduced forms, and with high purity. The stability and purity are especially relevant for pharmaceutical compositions for the treatment of disease. The compounds are useful for treatment of e.g. tauopathies, such as Alzheimer's disease, and also as prodrugs for the corresponding oxidized thioninium drugs.

公开(公告)号：US11751471B2

公开(公告)日：2023-09-05

申请号：US17669798

申请日：2022-02-11

Applicant: Crius Technology Group, Inc.

Inventor： Phillip Bogdanovich

IPC: H04B3/00 ,  H04L25/00 ,  H10K85/60 ,  H04W4/80 ,  H04L41/0833 ,  C07C209/60 ,  C07C211/61 ,  C07C217/80 ,  C07D209/86 ,  C07D209/94 ,  C07D213/06 ,  C07D213/16 ,  C07D219/02 ,  C07D221/08 ,  C07D223/26 ,  C07D265/38 ,  C07D279/22 ,  C07D307/91 ,  C07D307/93 ,  C07D311/80 ,  C07D333/76 ,  C07D405/04 ,  C07D405/12 ,  C07D407/12 ,  C07D471/06 ,  C07D487/04 ,  C09B19/00 ,  C09B21/00 ,  C09B57/00 ,  C09B69/00 ,  C09K11/06 ,  H04B3/56 ,  H04L12/28 ,  H04L43/00 ,  H05B47/18 ,  H05B47/19 ,  H05B47/185 ,  H05B47/115 ,  H05B47/105 ,  H04B3/54 ,  H04L12/40 ,  H04L43/08 ,  H05B47/175 ,  H10K50/11 ,  H10K50/15 ,  H10K50/17 ,  H10K50/18

CPC classification number: H10K85/633 ,  C07C209/60 ,  C07C211/61 ,  C07C217/80 ,  C07D209/86 ,  C07D209/94 ,  C07D213/06 ,  C07D213/16 ,  C07D219/02 ,  C07D221/08 ,  C07D223/26 ,  C07D265/38 ,  C07D279/22 ,  C07D307/91 ,  C07D307/93 ,  C07D311/80 ,  C07D333/76 ,  C07D405/04 ,  C07D405/12 ,  C07D407/12 ,  C07D471/06 ,  C07D487/04 ,  C09B19/00 ,  C09B21/00 ,  C09B57/008 ,  C09B69/008 ,  C09K11/06 ,  H04B3/54 ,  H04B3/56 ,  H04L12/2816 ,  H04L12/40 ,  H04L41/0833 ,  H04L43/00 ,  H04W4/80 ,  H05B47/105 ,  H05B47/115 ,  H05B47/18 ,  H05B47/185 ,  H05B47/19 ,  H10K85/636 ,  H10K85/6572 ,  H10K85/6574 ,  H10K85/6576 ,  C07C2601/14 ,  C07C2603/18 ,  C07C2603/26 ,  C07C2603/52 ,  C07C2603/54 ,  C07C2603/94 ,  C07C2603/97 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1014 ,  C09K2211/1029 ,  C09K2211/1088 ,  C09K2211/1092 ,  H04L43/08 ,  H04L2012/2843 ,  H05B47/175 ,  H10K50/11 ,  H10K50/15 ,  H10K50/17 ,  H10K50/18 ,  H10K85/615 ,  H10K85/626 ,  Y02E10/549

Abstract: Methods, systems, and apparatus for monitoring and controlling electronic devices using wired and wireless protocols are disclosed. The systems and apparatus may monitor their environment for signals from electronic devices. The systems and apparatus may take and disambiguate the signals that are received from the devices in their environment to identify the devices and associate control signals with the devices. The systems and apparatus may use communication means to send control signals to the identified electronic devices. Multiple apparatuses or systems may be connected together into networks, including mesh networks, to make for a more robust architecture.

公开(公告)号：US10074805B2

公开(公告)日：2018-09-11

申请号：US15500853

申请日：2015-09-16

Applicant: UDC IRELAND LIMITED

Inventor： Junichi Tanabe ,  Flavio Luiz Benedito ,  Christian Lennartz

IPC: C07D401/04 ,  C07D471/06 ,  H01L51/00 ,  C09K11/02 ,  C09K11/06 ,  H01L51/50

CPC classification number: H01L51/0053 ,  C07D401/04 ,  C07D471/06 ,  C09B19/00 ,  C09B21/00 ,  C09B57/00 ,  C09B57/08 ,  C09K11/025 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1022 ,  C09K2211/1044 ,  C09K2211/1059 ,  H01L51/0062 ,  H01L51/0067 ,  H01L51/0072 ,  H01L51/5012 ,  H01L51/5016 ,  Y02E10/549

Abstract: The present invention relates to organic light emitting elements, comprising thermally activated delayed fluorescence (TADF) emitters and/or hosts on basis of phthalimide and naphthalimide materials, which have a sufficiently small energy gap between S1 and T1 (ΔEST) to enable up-conversion of the triplet exciton from T1 to S1. The organic light emitting elements show high electroluminescent efficiency.

公开(公告)号：US20180114925A1

公开(公告)日：2018-04-26

申请号：US15846655

申请日：2017-12-19

Applicant: UDC IRELAND LIMITED

Inventor： Junichi Tanabe ,  Christian Lennartz

IPC: H01L51/00 ,  C07D401/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/14 ,  C09K11/02 ,  C09K11/06

CPC classification number: H01L51/0072 ,  C07D249/20 ,  C07D249/22 ,  C07D401/04 ,  C07D401/10 ,  C07D401/14 ,  C07D403/04 ,  C07D403/10 ,  C07D403/14 ,  C07D413/04 ,  C07D413/10 ,  C07D413/14 ,  C07D417/04 ,  C07D417/10 ,  C07D417/14 ,  C07D487/04 ,  C09B15/00 ,  C09B17/00 ,  C09B19/00 ,  C09B21/00 ,  C09B57/00 ,  C09B57/008 ,  C09K11/02 ,  C09K11/025 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1029 ,  C09K2211/1033 ,  C09K2211/1037 ,  C09K2211/1044 ,  C09K2211/1059 ,  H01L51/00 ,  H01L51/0054 ,  H01L51/0067 ,  H01L51/0071 ,  H01L51/50 ,  H01L51/5012 ,  H01L51/5028 ,  H01L2251/552 ,  H05B33/14 ,  Y02E10/549

Abstract: The present invention relates to organic light emitting elements, comprising thermally activated delayed fluorescence (TADF) emitters and/or hosts on basis of benzotriazoles, which have a sufficiently small energy gap between S1 and T1 (ΔEST) to enable up-conversion of the triplet exciton from T1 to S1. The organic light emitting elements show high electroluminescent efficiency.

公开(公告)号：US20170352811A1

公开(公告)日：2017-12-07

申请号：US15611901

申请日：2017-06-02

Applicant: Samsung Electronics Co., Ltd.

Inventor： Yeong Suk CHOI ,  Ohkyu KWON ,  Youn Hee LIM ,  Hyesung CHOI ,  Moon Gyu HAN ,  Hiromasa SHIBUYA ,  Yong Wan JIN ,  Katsunori SHIBATA

IPC: H01L51/00 ,  C07F7/08 ,  H01L27/30 ,  C07D471/14 ,  C07D471/04 ,  C07D421/14 ,  C07D421/04 ,  C07D495/04

CPC classification number: H01L51/0053 ,  C07B59/002 ,  C07D421/04 ,  C07D421/14 ,  C07D471/04 ,  C07D471/14 ,  C07D495/04 ,  C07D495/14 ,  C07D513/04 ,  C07D517/04 ,  C07F7/0816 ,  C09B15/00 ,  C09B21/00 ,  C09B23/04 ,  C09B57/00 ,  H01L27/307 ,  H01L51/0062 ,  H01L51/0071 ,  H01L51/0072 ,  H01L51/0074 ,  H01L51/0094 ,  H01L51/4253

Abstract: A compound represented by Chemical Formula 1, and a photoelectric device, an image sensor, and an electronic device including the same are disclosed. In Chemical Formula 1, each substituent is the same as defined in the detailed description.

公开(公告)号：US20170352493A1

公开(公告)日：2017-12-07

申请号：US15683118

申请日：2017-08-22

Applicant: FUJIFILM Corporation

Inventor： Naoyuki HANAKI ,  Yukio TANI ,  Kousuke WATANABE ,  Katsumi KOBAYASHI

IPC: H01G9/20 ,  C09B57/10

CPC classification number: H01G9/2059 ,  C09B15/00 ,  C09B19/00 ,  C09B21/00 ,  C09B23/14 ,  C09B23/145 ,  C09B57/008 ,  C09B57/10 ,  H01G9/20 ,  Y02E10/542

Abstract: Provided are a ruthenium complex dye having a water content of 0.2% to 4.0% by mass; a dye solution including the ruthenium complex dye; a photoelectric conversion element having semiconductor fine particles having the ruthenium complex dye carried thereon; and a dye-sensitized solar cell including the photoelectric conversion element.

公开(公告)号：US20170267652A1

公开(公告)日：2017-09-21

申请号：US15615225

申请日：2017-06-06

Applicant: EUPHARMA PTY LTD

Inventor： Malvin Eutick

IPC: C07D279/22 ,  A61K31/5415 ,  B01D9/02

CPC classification number: C07D279/22 ,  A61K31/5415 ,  B01D9/02 ,  C09B21/00

Abstract: A process for the purification of diaminophenothiazinium compounds, and particularly of methylene blue, is described. The process provides for simple and effective purification by reduction of the post-synthesis or commercially available diaminophenothiazinium compound to form a reduced complex thereof. This can then be purified in a more straightforward manner than the original compound by, for example, recrystallization before being allowed to oxidise back to the diaminophenothiazinium compound.

公开(公告)号：US09685615B2

公开(公告)日：2017-06-20

申请号：US14901533

申请日：2014-07-02

Applicant: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

Inventor： Masaki Numata ,  Takuma Yasuda ,  Jiyoung Lee ,  Asuka Yoshizaki ,  Chihaya Adachi

IPC: C07D405/04 ,  C07D405/10 ,  C07D405/14 ,  C07D413/14 ,  H01L51/00 ,  C09K11/06 ,  C07D409/04 ,  C07D409/10 ,  C07D491/107 ,  C07D495/10 ,  C07D519/00 ,  C09B11/28 ,  C09B15/00 ,  C09B17/02 ,  C09B19/00 ,  C09B21/00 ,  C09B57/00 ,  H01L51/50

CPC classification number: H01L51/0072 ,  C07D405/04 ,  C07D405/10 ,  C07D405/14 ,  C07D409/04 ,  C07D409/10 ,  C07D413/14 ,  C07D491/107 ,  C07D495/10 ,  C07D519/00 ,  C09B11/28 ,  C09B15/00 ,  C09B17/02 ,  C09B19/00 ,  C09B21/00 ,  C09B57/00 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1029 ,  C09K2211/1033 ,  C09K2211/1088 ,  C09K2211/145 ,  H01L51/005 ,  H01L51/0071 ,  H01L51/0073 ,  H01L51/5012

Abstract: A compound represented by the following general formula is useful as a light emitting material. X represents an oxygen atom or a sulfur atom. R1 to R8 represent a hydrogen atom or a substituent, provided that at least one of R1 to R8 is a carbazolyl group, etc.

公开(公告)号：US20170088534A1

公开(公告)日：2017-03-30

申请号：US15373224

申请日：2016-12-08

Applicant: WisTa Laboratories Ltd.

Inventor： Scott CLUNAS ,  John Mervyn Davd STOREY ,  Janet Elizabeth RICKARD ,  David HORSLEY ,  Charles Robert HARRINGTON ,  Claude Michel WISCHIK

IPC: C07D311/82 ,  A61K31/5377 ,  A61K31/4025 ,  G01N33/68 ,  A61K9/00 ,  A61K45/06 ,  A61K31/4745 ,  A61K49/00 ,  A61K31/352 ,  A61K31/4545

CPC classification number: C07D311/82 ,  A61K9/0053 ,  A61K31/352 ,  A61K31/382 ,  A61K31/4025 ,  A61K31/4545 ,  A61K31/4745 ,  A61K31/498 ,  A61K31/5377 ,  A61K31/538 ,  A61K45/06 ,  A61K49/00 ,  C07D241/46 ,  C07D265/38 ,  C07D311/84 ,  C07D311/90 ,  C07D335/12 ,  C07D335/14 ,  C07D335/20 ,  C07D491/16 ,  C07D491/22 ,  C07D493/16 ,  C09B11/24 ,  C09B11/28 ,  C09B17/00 ,  C09B19/00 ,  C09B21/00 ,  C09B57/00 ,  G01N33/6896 ,  G01N2800/7047

Abstract: Described are a compound of formula (II) or (III): The compounds are effective in the treatment of disease, including a tauopathy condition or a disease of tau protein aggregation.

公开(公告)号：US09590190B2

公开(公告)日：2017-03-07

申请号：US14347618

申请日：2014-01-13

Applicant: Shenzhen China Star Optoelectronics Technology Co., Ltd.

Inventor： Shidang Xu ,  Zhenguo Chi ,  Yi Zhang ,  Jiarui Xu ,  Yifan Wang ,  Qinghua Zou

IPC: H01L51/54 ,  C09K11/06 ,  H01L51/00 ,  C07D209/86 ,  C07D417/14 ,  C07D279/22 ,  H01L51/50 ,  H01L51/52

CPC classification number: H01L51/0072 ,  C07D209/86 ,  C07D279/22 ,  C07D417/14 ,  C09B21/00 ,  C09B57/00 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1037 ,  C09K2211/1066 ,  H01L51/0071 ,  H01L51/5012 ,  H01L51/5068 ,  H01L51/5084 ,  H01L51/5234

Abstract: The present invention provides a thermally activated delayed fluorescence material, a method of synthesizing the same and an OLED device using the same. The thermally activated delayed fluorescence material includes a structure formula 1 as wherein the group Ar1 is identical to or different from the group Ar2, and the group Ar1 and the group Ar2 are consisted of carbazole and/or phenothiazine. The thermally activated delayed fluorescence material has a higher glass transition temperature, high thermal stability and excellent luminous efficiency. The method of synthesizing the same has simplified steps, easily purified product, high yield, and luminous and thermal properties of the product can be adjusted by connecting to differentiated functional groups. The OLED device using the same has a light emitting layer of high fluorescence efficiency and long-term stability, so that luminous efficiency and service life of the OLED device can meet practical demand.

Abstract translation: 本发明提供一种热活化延迟荧光材料，其合成方法和使用其的OLED器件。 热活化延迟荧光材料包括结构式1，其中基团Ar1与Ar2相同或不同，Ar1和Ar2组由咔唑和/或吩噻嗪组成。 热活化延迟荧光材料具有较高的玻璃化转变温度，高热稳定性和优异的发光效率。 其合成方法具有简化的步骤，容易纯化的产物，高产率，产物的发光和热性能可通过连接到差异官能团进行调整。 使用其的OLED器件具有高荧光效率和长期稳定性的发光层，使得OLED器件的发光效率和使用寿命能够满足实际需求。