Laboratory automation system implementing efficient path for material and lab ware transfers

    公开(公告)号:US11841374B2

    公开(公告)日:2023-12-12

    申请号:US17620033

    申请日:2020-06-26

    Applicant: Zymergen Inc.

    Abstract: Systems, methods and computer-readable media are provided for determining a sequential ordering of predefined transfers for transferring an object from source points of a source array to destination points of a destination array in a laboratory automation system. For each transition to a next transfer, first and second component travel costs between current and next transfer positions are determined. A transition travel cost is determined from the first and second component travel costs. The cost of each sequential ordering of the predefined transfers is based upon an aggregate of the transition travel costs for each ordering of the transfers. The resolved sequential ordering may be based upon the sequential ordering that has the lowest cost.

    Apparatus for withdrawing a liquid sample from selected ones of a plurality of containers
    3.
    发明授权
    Apparatus for withdrawing a liquid sample from selected ones of a plurality of containers 有权
    用于从多个容器中的某些容器中取出液体样品的装置

    公开(公告)号:US08349278B2

    公开(公告)日:2013-01-08

    申请号:US12515043

    申请日:2007-11-15

    Abstract: Apparatus (1) for withdrawing respective liquid samples from vials (2) which are closed by closure caps (4) includes a plurality of racks (7) for accommodating the vials (2). A device (10) including a housing (25) is slideably carried on a gantry (9) which in turn is slideably carried on guide tracks (12) to provide two degrees of movement of the device (10) for selective alignment of the device (10) with the vials (2). An abutment member (43) is driven vertically by a second gearwheel (51) by a drive shaft (27) through a first gearwheel (40) and a dog clutch (52). A cannula which is secured within a first gear rack (33) is driven vertically by the first gearwheel (40). On engagement of the abutment member (43) with the closure cap (4) of the selected vial (2), the clutch (52) decouples the second gearwheel (51) from the first gearwheel (40) so that the cannula (28) is urgeable through the closure cap (4) into the vial (2).

    Abstract translation: 用于从由瓶盖(4)封闭的小瓶(2)中取出各个液体样品的装置(1)包括多个容纳小瓶(2)的机架(7)。 包括壳体(25)的装置(10)可滑动地承载在台架(9)上,所述台架(9)又可滑动地承载在引导轨道(12)上,以提供装置(10)的两度运动,用于选择性地对准装置 (10)与小瓶(2)。 邻接构件(43)由驱动轴(27)通过第一齿轮(40)和爪形离合器(52)由第二齿轮(51)垂直地驱动。 固定在第一齿条(33)内的套管由第一齿轮(40)垂直地驱动。 在邻接构件(43)与所选择的小瓶(2)的封闭盖(4)接合时,离合器(52)将第二齿轮(51)与第一齿轮(40)分离,使得套管(28) 可通过封闭帽(4)推入瓶子(2)中。

    Method and Arrangement for Handling Test Tubes
    6.
    发明申请
    Method and Arrangement for Handling Test Tubes 有权
    处理试管的方法和布置

    公开(公告)号:US20160209438A1

    公开(公告)日:2016-07-21

    申请号:US14915911

    申请日:2014-09-03

    Abstract: A novel solution is proposed for processing a test tube transported on a test tube carrier by a conveyor so that spilling of the liquid in the test tube is reduced or even prevented, particularly an arrangement for sequencing and guiding travel of test tube carriers transported on at least one conveyor. The arrangement includes at least one rotatable deviator positioned to intersect the at least one conveyor. The deviator includes a horizontal deviator plate including at least one grip for receiving a test tube carrier. One contact surface is positioned vertically at a distance from the deviator plate and aligned with the grip. The contact surface is formed to contact the test tube carrier at a distance from the contact level of the grip and the carrier.

    Abstract translation: 提出了一种新颖的解决方案,用于处理通过输送机在试管载体上运送的试管,使得试管中的液体溢出减少或甚至被防止,特别是用于排放和引导在其上运输的试管载体的行程的装置 至少一个输送机。 该装置包括定位成与至少一个输送机相交的至少一个可旋转偏转器。 偏转器包括水平偏转板,其包括至少一个用于接收试管载体的把手。 一个接触表面垂直定位在偏离板的一定距离处并与把手对准。 接触表面形成为在与夹具和载体的接触水平一定距离处与试管载体接触。

    DEVICE FOR WITHDRAWING A LIQUID SAMPLE FROM A CONTAINER OR FOR DISCHARGING A LIQUID SAMPLE INTO A CONTAINER, AND APPARATUS INCORPORATING THE DEVICE FOR WITHDRAWING LIQUID SAMPLES FROM RESPECTIVE ONES OF A PLURALITY OF CONTAINERS OR FOR DISCHARGING LIQUID SAMPLES INTO RESPECTIVE ONES OF A PLURALITY OF CONTAINERS
    7.
    发明申请
    DEVICE FOR WITHDRAWING A LIQUID SAMPLE FROM A CONTAINER OR FOR DISCHARGING A LIQUID SAMPLE INTO A CONTAINER, AND APPARATUS INCORPORATING THE DEVICE FOR WITHDRAWING LIQUID SAMPLES FROM RESPECTIVE ONES OF A PLURALITY OF CONTAINERS OR FOR DISCHARGING LIQUID SAMPLES INTO RESPECTIVE ONES OF A PLURALITY OF CONTAINERS 有权
    用于从集装箱中取出液体样品或将液体样品从集装箱中排出的装置,以及装有装置的装置,用于将液体样品从多个集装箱的相关装置中取出,或将液体样品排入多个集装箱的相关装置

    公开(公告)号:US20100212437A1

    公开(公告)日:2010-08-26

    申请号:US12515043

    申请日:2007-11-15

    Abstract: Apparatus (1) for withdrawing respective liquid samples from vials (2) which are closed by closure caps (4) penetratable by a pointed cannula comprises a plurality of racks (7) for accommodating the vials (2). A device (10) comprising a housing (25) is slideably carried on a gantry (9) which in turn is slideably carried on guide tracks (12) to provide two degrees of movement of the device (10) for selective alignment of the device (10) with the vials (2). An abutment member (43) which is vertically slideable in the housing (25) of the device (10) is driven by a second gearwheel (51) by a drive shaft (27) along which the housing (25) is slideably mounted through a first gearwheel (40) and a dog clutch (52). A cannula which is secured within a first gear rack (33) is driven upwardly and downwardly within the housing (25) by the first gearwheel (40) which is driven by the drive shaft (27). On engagement of the abutment member (43) with the closure cap (4) of the selected vial (2), the clutch (52) decouples the second gearwheel (51) from the first gearwheel (40) so that the cannula (28) is urgeable through the closure cap (4) into the vial (2) for withdrawing the liquid sample. The clutch (52) retains the second gearwheel (51) decoupled from the first gearwheel (40) until the cannula (28) has been withdrawn from the closure cap (4) in order to prevent displacement of the closure cap (4) during withdrawal of the cannula (28) therethrough.

    Abstract translation: 用于从通过尖头套管穿透的封闭盖(4)封闭的小瓶(2)中取出各个液体样品的装置(1)包括用于容纳小瓶(2)的多个机架(7)。 包括壳体(25)的装置(10)可滑动地承载在台架(9)上,所述台架(9)又可滑动地承载在导轨(12)上,以提供装置(10)的两个移动方向,用于选择性地对准装置 (10)与小瓶(2)。 在装置(10)的壳体(25)中可垂直滑动的邻接构件(43)由第二齿轮(51)由驱动轴(27)驱动,壳体(25)沿着该驱动轴可滑动地安装 第一齿轮(40)和爪形离合器(52)。 固定在第一齿条(33)内的套管通过由驱动轴(27)驱动的第一齿轮(40)在壳体(25)内向上和向下驱动。 在邻接构件(43)与所选择的小瓶(2)的封闭盖(4)接合时,离合器(52)将第二齿轮(51)与第一齿轮(40)分离,使得套管(28) 可通过封闭盖(4)推入瓶子(2)中以抽出液体样品。 离合器(52)保持第二齿轮(51)与第一齿轮(40)分离,直到套管(28)已经从封闭盖(4)中取出,以防止在退出时封闭盖(4)的移位 (28)穿过。

    Reaction Cuvette Loading Device and Chemiluminescence Immunoassay Apparatus
    9.
    发明申请
    Reaction Cuvette Loading Device and Chemiluminescence Immunoassay Apparatus 审中-公开
    反应比色杯装载装置和化学发光免疫测定装置

    公开(公告)号:US20170067883A1

    公开(公告)日:2017-03-09

    申请号:US15122893

    申请日:2015-05-08

    Abstract: Provided are a reaction cuvette loading device and a fully automatic chemiluminescence immunoassay apparatus. The reaction cuvette loading device comprises a transmission mechanism and a push mechanism, wherein the transmission mechanism comprises a baseplate and a first horizontal transmission mechanism provided on the baseplate; the push mechanism comprises a support assembly, a second horizontal transmission mechanism provided on the support assembly, and a push rod connected to the second horizontal transmission mechanism; and the push mechanism further comprises a direction guiding control block comprising a starting end provided at a terminal point of a cuvette pushing stroke of the push rod, a termination end provided at a starting point of the cuvette pushing stroke of the push rod, and a return track provided between the starting end and the termination end and bypassing the cuvette pushing stroke, and the separation distance between the starting end and termination end is not less than one vessel position and not more than two vessel positions.

    Abstract translation: 提供反应池加载装置和全自动化学发光免疫测定装置。 反应比色皿装载装置包括传动机构和推动机构,其中传动机构包括基板和设置在基板上的第一水平传动机构; 推动机构包括支撑组件,设置在支撑组件上的第二水平传动机构和连接到第二水平传动机构的推杆; 并且所述推动机构还包括方向引导控制块,所述方向引导控制块包括设置在所述推杆的反应杯推动行程的终点处的起始端,设置在所述推杆的比色杯推动行程的起点处的终止端, 返回轨道设置在起始端和终止端之间,并绕过比丘杯推动行程,起始端和终端之间的间隔距离不小于一个船只位置,不得超过两个船只位置。

    SPECIMEN TRANSPORT DEVICE, SPECIMEN PRETREATMENT SYSTEM, ANALYSIS SYSTEM, AND SPECIMEN TESTING AUTOMATION SYSTEM
    10.
    发明申请
    SPECIMEN TRANSPORT DEVICE, SPECIMEN PRETREATMENT SYSTEM, ANALYSIS SYSTEM, AND SPECIMEN TESTING AUTOMATION SYSTEM 有权
    样本运输设备,样本预处理系统,分析系统和样本测试自动化系统

    公开(公告)号:US20160251164A1

    公开(公告)日:2016-09-01

    申请号:US15028207

    申请日:2014-12-10

    Abstract: In the prior art, in transport lines equipped with multiple stages of transport lines driven in different directions, it was necessary that drive power sources for driving the belts of the transport lines be provided in a number equal to the number of transport lines. This led to an increased number of drive power sources and to an unavoidable increase in the power consumed by the device as a whole. In the present invention, there is adopted a mechanism for the parallel driving of a plurality of transport lines by a single drive power source, whereby the number of drive power sources needed to drive the transport lines can be reduced, as can the power consumed by the system.

    Abstract translation: 在现有技术中,在配备有沿不同方向驱动的多级输送线的运输线路中,需要以与输送线数相等的数量来设置用于驱动输送线的皮带的驱动力源。 这导致驱动电源数量的增加以及整个设备消耗的功率的不可避免的增加。 在本发明中,采用了用于通过单个驱动电源并行驱动多个输送线的机构,由此能够减少驱动输送线路所需的驱动电力的数量,消耗的电力也可以减少 系统。

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