公开(公告)号：WO2007035642A3

公开(公告)日：2007-08-16

申请号：PCT/US2006036299

申请日：2006-09-15

Applicant: BIOTROVE INC ,  YODER KARL ,  BRENAN COLIN ,  LINTON JOHN ,  HASAN LEILA ,  ELLIS ROBERT ,  KATZ ARRIN ,  MORRISON TOM ,  FONSECA JORGE

Inventor： YODER KARL ,  BRENAN COLIN ,  LINTON JOHN ,  HASAN LEILA ,  ELLIS ROBERT ,  KATZ ARRIN ,  MORRISON TOM ,  FONSECA JORGE

IPC: C12P19/34 ,  C12M1/34

CPC classification number: B01L3/508 ,  B01L3/50857 ,  B01L7/02 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/0684 ,  B01L2200/0689 ,  B01L2300/021 ,  B01L2300/0636 ,  B01L2300/0819 ,  B01L2300/0822 ,  B01L2300/1822 ,  B01L2300/1838 ,  B01L2300/185

Abstract: A system for thermal cycling a plurality of samples. The system includes a case having a fluid-tight cavity defining an interior volume. A microfluidic array is disposed in the interior volume, the array including a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces. A thermal cycler having at least one thermally controlled surface is adapted to thermally contact the case.

Abstract translation: 一种用于热循环多个样品的系统。 该系统包括具有限定内部容积的流体密封腔的壳体。 微流体阵列设置在内部容积中，该阵列包括具有一对相对表面，厚度以及贯穿表面之间的厚度的多个通孔的材料片。 具有至少一个热控表面的热循环仪适于热接触外壳。

公开(公告)号：WO2007054135A1

公开(公告)日：2007-05-18

申请号：PCT/EP2006/003457

申请日：2006-04-13

Applicant: AUTODOSE SA ,  PLUVINAGE, Loic ,  VALELLA, Antonio ,  BERINI, Gian-Luigi

Inventor： PLUVINAGE, Loic ,  VALELLA, Antonio ,  BERINI, Gian-Luigi

IPC: G01G17/06 ,  B01L3/02 ,  F16K3/02

CPC classification number: G01G13/02 ,  B01L3/021 ,  B01L2200/0657 ,  B01L2200/143 ,  B01L2300/021 ,  B01L2300/049

Abstract: The invention is directed to a dispensing unit suitable to precise! dispense material in powder and/or granular form. The dispensing device comprises a gate valve opening sealingl closed b a blend. A control unit, which is interconnected to a scaling device, controls the opening of the gate valve opening b the position of the blend. The precise amount of the material is adjusted in relation to the signal of the scaling device.

Abstract translation: 本发明涉及适合于精确的分配单元！ 以粉末和/或颗粒形式分配材料。 分配装置包括一个封闭的门阀开口密封件b。 与缩放装置相互连接的控制单元控制门阀开口b打开混合物的位置。 相对于缩放装置的信号调整材料的精确量。

公开(公告)号：WO2006102421A9

公开(公告)日：2007-03-08

申请号：PCT/US2006010424

申请日：2006-03-21

Applicant: APPLERA CORP ,  CARRILLO ALBERT L ,  FAWCETT ADRIAN ,  HARDING IAN A ,  LU MIKE Y ,  OLDHAM MARK F

Inventor： CARRILLO ALBERT L ,  FAWCETT ADRIAN ,  HARDING IAN A ,  LU MIKE Y ,  OLDHAM MARK F

IPC: C12M1/34 ,  C12M3/00

CPC classification number: B01L3/0268 ,  B01L3/5025 ,  B01L3/5027 ,  B01L3/50851 ,  B01L3/50853 ,  B01L7/52 ,  B01L2200/021 ,  B01L2200/0605 ,  B01L2200/0642 ,  B01L2200/0689 ,  B01L2200/142 ,  B01L2300/021 ,  B01L2300/044 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0487 ,  G01N35/04

Abstract: In a high-density sequence detection system, an apparatus for transporting a microplate. A control system provides a thermocycler control signal to regulate a desired thermal output of a thermocycler block. A frame has a first side, a second side, and an opening that extends through the first side and the second side. A window is positioned in the opening and a circumferential seal is positioned around a periphery of the opening at the second side. The seal has a peripheral lip that seals against the microplate. A clamp is adapted to engage and displace the frame from an unclamped position to a clamped position, wherein in the unclamped position, the microplate is displaced away from the thermocycler block and in the clamped position, the clamp urges the microplate against the thermocycler block. In some embodiments the peripheral lip is positioned radially inward of the periphery of the opening.

Abstract translation: 在高密度序列检测系统中，用于运送微孔板的装置。 控制系统提供热循环器控制信号以调节热循环器块的期望的热输出。 框架具有延伸穿过第一侧和第二侧的第一侧，第二侧和开口。 窗口定位在开口中，并且周向密封件围绕第二侧的开口的周边定位。 密封件具有密封微孔板的周边唇缘。 夹具适于将框架从未夹紧位置接合并移位到夹紧位置，其中在未夹紧位置，微孔板远离热循环器块移动，并且在夹紧位置，夹具将微孔板推向热循环器块。 在一些实施例中，外围唇缘位于开口周边的径向内侧。

公开(公告)号：WO2007020582A1

公开(公告)日：2007-02-22

申请号：PCT/IB2006/052782

申请日：2006-08-11

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  SCHAEFER, Danny, G., A. ,  VAN DEN BIJGAART, Adrianus, W., D., M. ,  DE JONG, Michiel ,  DE GIER, Ronald, C. ,  MOLENAAR, Jacobus, F. ,  MAESSEN, Ralph, T., H. ,  WEHRENS, Roger, M., H., G. ,  BOUMA, Peter, H. ,  VAN HAAG, Chris

Inventor： SCHAEFER, Danny, G., A. ,  VAN DEN BIJGAART, Adrianus, W., D., M. ,  DE JONG, Michiel ,  DE GIER, Ronald, C. ,  MOLENAAR, Jacobus, F. ,  MAESSEN, Ralph, T., H. ,  WEHRENS, Roger, M., H., G. ,  BOUMA, Peter, H. ,  VAN HAAG, Chris

IPC: B01L3/00

CPC classification number: G01N35/00029 ,  B01L3/50273 ,  B01L3/502738 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/087 ,  B01L2400/0478 ,  B01L2400/0487 ,  B01L2400/0644 ,  G01N2035/00237

Abstract: The invention provides a system (10), a processing apparatus (30), a sample unit (20), a reagent unit (25) and a method for processing a biological sample inside the sample unit. The system comprises at least a processing apparatus and a sample unit, the sample unit comprises a plurality of microfluidic elements, the processing apparatus comprises actuation means capable of actuating at the microfluidic elements such that a quick, inexpensive and accurate analysis of the biological sample is possible.

Abstract translation: 本发明提供一种系统（10），处理装置（30），样品单元（20），试剂单元（25）以及用于处理样品单元内的生物样品的方法。 该系统至少包括一个处理设备和一个样品单元，该样品单元包括多个微流体元件，该处理设备包括能够致动微流体元件的致动装置，使得生物样品的快速，便宜且准确的分析是 可能。

公开(公告)号：WO2007016931A1

公开(公告)日：2007-02-15

申请号：PCT/EP2005/008079

申请日：2005-07-25

Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. ,  NIJMEGEN UNIVERSITY ,  WAGENINGEN UNIVERSITY ,  TRIEU, Hoc Khiem ,  BOLLEROTT, Michael ,  KEMMERLING, Martin ,  HILDEBRAND, Robert ,  VAN HEST, Jan ,  RUTJES, Floris ,  KOCH, Kaspar ,  NIEUWLAND, Pieter ,  VAN BEEK, Teris A. ,  SUDHÖLTER, Ernst J.R. ,  BOOM, Remko M. ,  JANSSEN, Anja E.M.

Inventor： TRIEU, Hoc Khiem ,  BOLLEROTT, Michael ,  KEMMERLING, Martin ,  HILDEBRAND, Robert ,  VAN HEST, Jan ,  RUTJES, Floris ,  KOCH, Kaspar ,  NIEUWLAND, Pieter ,  VAN BEEK, Teris A. ,  SUDHÖLTER, Ernst J.R. ,  BOOM, Remko M. ,  JANSSEN, Anja E.M.

IPC: B01L9/00

CPC classification number: B01L9/00 ,  B01L9/527 ,  B01L2200/027 ,  B01L2300/021 ,  B01L2300/022 ,  B01L2300/0627 ,  B01L2300/0861 ,  B01L2300/1805 ,  B01L2300/1822 ,  B01L2300/185 ,  B01L2400/04 ,  B01L2400/0487

Abstract: A chip-holder for holding a micro-fluidic chip comprises means for detachably fixing the micro-fluidic chip in the chip-holder and at least one process control device configured to support control or monitoring of a chemical process in the micro-fluidic chip, wherein the chip-holder is configured such that the process control device and the micro-fluidic chip are directly and detachably coupled when the micro-fluidic chip is fixed in the chip-holder. Such a chip-holder brings along the advantage that the micro-fluidic chip can easily be removed and exchanged while the process control device can be reused. This reduces running costs of a chemical microreactor system drastically and allows for a very flexible usage of a chemical microreactor system.

Abstract translation: 用于保持微流体芯片的芯片保持器包括用于将微流体芯片可拆卸地固定在芯片保持器中的装置和被配置为支持微流体芯片中的化学过程的控制或监视的至少一个过程控制装置， 其中，所述芯片保持器构造成使得当所述微流体芯片固定在所述芯片保持器中时，所述过程控制装置和所述微流体芯片是直接可拆卸地耦合的。 这样的芯片保持器具有微流体芯片可以容易地被去除和交换而可以重复使用过程控制装置的优点。 这可以显着降低化学微反应器系统的运行成本，并允许非常灵活地使用化学微反应器系统。

公开(公告)号：WO2007016421A2

公开(公告)日：2007-02-08

申请号：PCT/US2006/029584

申请日：2006-08-01

Applicant: INVITROGEN CORPORATION ,  UNGER, Alex ,  TOPFER, Meike ,  BUSCH, Nicole ,  HYNEK, Tom ,  AIDEHAG, Fredrik ,  PELMAN, Todd ,  NALEY, Martin

Inventor： UNGER, Alex ,  TOPFER, Meike ,  BUSCH, Nicole ,  HYNEK, Tom ,  AIDEHAG, Fredrik ,  PELMAN, Todd ,  NALEY, Martin

IPC: C12M3/00

CPC classification number: B01L3/5457 ,  B01L3/0272 ,  B01L3/523 ,  B01L3/545 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/022 ,  B01L2300/028 ,  B01L2300/042 ,  B01L2300/043 ,  B01L2300/047 ,  B01L2300/0851 ,  B01L2300/0858 ,  B65D1/0223 ,  B65D2203/02 ,  B67D7/00 ,  C12M99/00 ,  G01N2035/00673 ,  G01N2035/00792 ,  G01N2035/0436 ,  G06Q10/087 ,  G06Q30/0621 ,  G06Q30/0633 ,  G06Q30/0641 ,  G09F3/00 ,  G09F23/00

Abstract: The invention relates to systems and methods for marketing and using products such as liquid materials, especially liquid reagents for use in microbiological and cellular biological laboratory settings include the use of unique color and simple numeric or alphanumeric identifiers to quickly and easily identify any product from a catalog list of products. Methods of marketing, advertising and producing such products are also disclosed. Particular embodiments include products, product packaging and product labeling. The invention also relates to collars and sleeves for containers, as well as related methods of use.

Abstract translation: 本发明涉及用于销售和使用诸如液体材料，特别是用于微生物和细胞生物学实验室设备的液体试剂的产品的系统和方法，包括使用独特的颜色和简单的数字或字母数字标识符来快速和容易地鉴别来自 目录产品清单。 还披露了营销，广告和制作这些产品的方法。 具体实施例包括产品，产品包装和产品标签。 本发明还涉及用于容器的套环和套筒以及相关的使用方法。

公开(公告)号：WO2006130111A1

公开(公告)日：2006-12-07

申请号：PCT/SE2006/050178

申请日：2006-05-31

Applicant: GYROS PATENT AB ,  BERGSTRÖM, Mårten ,  BIELIK, Robert ,  SÖDERMAN, Tobias ,  OHLSTRÖM, Agneta

Inventor： BERGSTRÖM, Mårten ,  BIELIK, Robert ,  SÖDERMAN, Tobias ,  OHLSTRÖM, Agneta

IPC: B01L3/00 ,  B81B1/00 ,  G01N33/48

CPC classification number: G01N35/00732 ,  B01L3/5027 ,  B01L2200/025 ,  B01L2300/021 ,  B01L2300/0806 ,  G01N35/1011 ,  G01N2035/1034 ,  Y10T137/86389

Abstract: The present invention relates to a method for determining the identity of a microfluidic device and a home position by means of a set of home position marks on the microfluidic device, which is of the type used in a microfluidic system. Said method comprises following phases: a microfluidic device scanning phase, wherein a microfluidic device is scanned for mark identifiers; a microfluidic device identifying phase, wherein at least one a characteristic feature of the set of home marks is/ are determined and used for identifying the identity of the microfluidic device; a home position determining phase, wherein the home position is determined by the use of at least a subset of the home position marks identified during said previous phases. The present invention relates to a set of home marks, a microfluidic device carrying such a set of home marks, a microfluidic system, a computer program product and a computer program on a computer usable medium.

Abstract translation: 本发明涉及一种通过微流体装置上的一组原始位置标记来确定微流体装置和原始位置的身份的方法，其是在微流体系统中使用的类型。 所述方法包括以下阶段：微流体装置扫描阶段，其中扫描微流体装置用于标记识别符; 微流体装置识别阶段，其中确定并且使用该组归属标记中的至少一个特征特征来识别微流体装置的身份; 原始位置确定阶段，其中通过使用在所述先前阶段期间识别的原始位置标记的至少一个子集来确定原始位置。 本发明涉及一套家用商标，一种在这种计算机可用介质上携带这样的家庭标记的微流体装置，微流体系统，计算机程序产品和计算机程序。

公开(公告)号：WO2006121510A2

公开(公告)日：2006-11-16

申请号：PCT/US2006011090

申请日：2006-03-24

Applicant: THERANOS INC ,  HOLMES ELIZABETH A ,  ROY SHAUNAK ,  HOWARD JOHN ,  WANG CHENGWANG ,  GIBBONS IAN ,  KEMP TIM ,  TODD CHRIS ,  ORAL RON ,  ZENG SHULIN ,  FENTON JEFF ,  QI SHIZE DANIEL

Inventor： HOLMES ELIZABETH A ,  ROY SHAUNAK ,  HOWARD JOHN ,  WANG CHENGWANG ,  GIBBONS IAN ,  KEMP TIM ,  TODD CHRIS ,  ORAL RON ,  ZENG SHULIN ,  FENTON JEFF ,  QI SHIZE DANIEL

IPC: A61B5/00

CPC classification number: G01N21/76 ,  A61B5/1411 ,  A61B5/1427 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1495 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150251 ,  A61B5/150763 ,  A61B5/150854 ,  A61B5/15142 ,  A61B5/157 ,  A61B5/412 ,  A61B5/417 ,  B01L3/50273 ,  B01L2300/021 ,  B01L2300/023 ,  B01L2300/044 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0877 ,  B01L2300/0883 ,  B01L2300/0887 ,  G01N33/50 ,  G01N33/53 ,  G01N33/5302 ,  G01N33/54386 ,  G01N2500/00 ,  G16H40/63 ,  Y02A90/26 ,  Y10T436/10 ,  Y10T436/11 ,  Y10T436/115831 ,  Y10T436/12 ,  Y10T436/143333

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

Abstract translation: 本发明在医疗器械领域。 具体地说，本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。

公开(公告)号：WO2006120656A1

公开(公告)日：2006-11-16

申请号：PCT/IE2006/000047

申请日：2006-05-05

Applicant: HAEMOGLOBAL BIOTECH LTD. ,  KENNEDY, John ,  KENNEDY, Julie ,  ROWLAND, Thomas

Inventor： KENNEDY, John ,  KENNEDY, Julie ,  ROWLAND, Thomas

IPC: G01N15/14

CPC classification number: A61B5/14546 ,  A61B5/14532 ,  A61B2560/0456 ,  B01L3/502715 ,  B01L2200/10 ,  B01L2300/021 ,  B01L2300/023 ,  B01L2300/0816 ,  B01L2300/0864

Abstract: A portable biological fluid testing system comprising at least one sensor cartridge ( 3) having at least one sensor, an analyser (1) adapted to analyse readings from said at least one sensor, said analyser (1) comprising means for calculating cell count and means for calculating at least one analyte measurement, and a data processor (2) for processing said results, said data processor (2) comprising an interactive database.

Abstract translation: 一种便携式生物流体测试系统，包括至少一个具有至少一个传感器的传感器盒（3），适于分析来自所述至少一个传感器的读数的分析器（1），所述分析器（1）包括用于计算细胞计数和装置 用于计算至少一种分析物测量值和用于处理所述结果的数据处理器（2），所述数据处理器（2）包括交互式数据库。

公开(公告)号：WO2006043181A3

公开(公告)日：2006-06-15

申请号：PCT/IB2005003985

申请日：2005-08-04

Applicant: SPINX INC ,  ZUCCHELLI PIERO ,  CALLENBACH TILO ,  LETTIERI GIAN-LUCA ,  METT HELMUT ,  SEMAC ISABELLE ,  VAN DE VYVER BART ,  WIOLAND HERVE

Inventor： ZUCCHELLI PIERO ,  CALLENBACH TILO ,  LETTIERI GIAN-LUCA ,  METT HELMUT ,  SEMAC ISABELLE ,  VAN DE VYVER BART ,  WIOLAND HERVE

IPC: B01L3/00

CPC classification number: B01J19/0093 ,  B01J2219/0081 ,  B01J2219/00891 ,  B01L3/5025 ,  B01L3/502707 ,  B01L3/502715 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2300/021 ,  B01L2300/0816 ,  B01L2300/0829 ,  B01L2300/0861 ,  B01L2400/0409 ,  G01N35/028 ,  G01N2035/00237 ,  G01N2035/00326 ,  G01N2035/0425

Abstract: The present invention is directed generally to devices and methods with the purpose of interfacing microfluidic devices with dispensing and fluid handling systems. Specifically, the present invention consists in the design of the inlets of a microfluidic device in such a way that multiple units can be loaded as a single compact device, with a unitary interface format which is compatible with existing industry standards.

Abstract translation: 本发明一般涉及用于将微流体装置与分配和流体处理系统进行接口的装置和方法。 具体地说，本发明在于以这样的方式设计微流体装置的入口，使得可以将多个单元作为单个紧凑装置加载，其具有与现有工业标准兼容的单一接口格式。