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    GOLD SENSOR
    11.
    发明申请
    GOLD SENSOR 审中-公开
    金色传感器

    公开(公告)号：WO2017131726A1

    公开(公告)日：2017-08-03

    申请号：PCT/US2016/015550

    申请日：2016-01-29

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： BENGALI, Sadiq ,  GIRI, Manish

    IPC: G01N33/553 ,  G01N35/08 ,  B01L3/00 ,  C01B33/025 ,  C01G7/00 ,  C01G35/00

    CPC classification number: B01L3/00 ,  B01L3/502707 ,  B01L2300/0663 ,  B01L2300/1827 ,  B01L2400/0442 ,  G01N33/553

    Abstract: A microfluidic diagnostic chip may, in an example, include a number of microfluidic channels defined in a substrate each microfluidic channel fluidly coupled to at least one fluidic slot; the at least one fluidic slot to receive a number of fluids, and a number of gold sensors each gold sensor having a thickness of between 1500 and 5000 angstroms (Å).

    Abstract translation: 在一个示例中，微流体诊断芯片可以包括在衬底中限定的多个微流体通道，每个微流体通道流体耦合到至少一个流体槽; 所述至少一个流体槽用于接收多种流体，以及多个金传感器，每个金传感器具有1500至5000埃的厚度。

    ELECTRODE INTEGRATION INTO ORGANS ON CHIP DEVICES
    12.
    发明申请
    ELECTRODE INTEGRATION INTO ORGANS ON CHIP DEVICES 审中-公开
    电极集成到芯片器件上的器官

    公开(公告)号：WO2017106727A1

    公开(公告)日：2017-06-22

    申请号：PCT/US2016/067294

    申请日：2016-12-16

    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE

    Inventor： HENRY, Olivier ,  VAN DER MEER, Andries ,  INGBER, Donald, E.

    IPC: C12N5/07 ,  C12M3/04 ,  B01L3/00 ,  G01N27/40 ,  G01N33/50

    CPC classification number: B01L3/502707 ,  B01L3/502715 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0887 ,  B81C3/00 ,  C12M41/46

    Abstract: A method of fabricating electrodes includes forming a first metallic film layer on an upper surface of a first material substrate, and attaching a first polymeric layer to the upper surface of the first material substrate to form a first opened microchannel. The method further includes forming a second metallic film layer on a portion of a lower surface of a second material substrate, and attaching a second polymeric layer to the lower surface of the second material substrate to form a second opened microchannel. The method also includes attaching the first opened microchannel to a bottom side of the membrane and the second opened microchannel to the top side of the membrane. The first metallic film layer and the second metallic film layer each constitute transparent electrodes and are positioned with the membrane therebetween.

    Abstract translation: 一种制造电极的方法包括：在第一材料基板的上表面上形成第一金属膜层;以及将第一聚合物层附着到第一材料基板的上表面以形成第一开口 微通道。 该方法还包括在第二材料基底的下表面的一部分上形成第二金属膜层，并将第二聚合物层附着到第二材料基底的下表面以形成第二开放的微通道。 该方法还包括将第一次打开的微通道连接到膜的底侧，并将第二次打开的微通道连接到膜的顶侧。 第一金属薄膜层和第二金属薄膜层各自构成透明电极，并且隔膜位于其间。

    ELECTROANALYTICAL DEVICES WITH PINS AND THREAD
    14.
    发明申请
    ELECTROANALYTICAL DEVICES WITH PINS AND THREAD 审中-公开
    带引脚和螺纹的电子器件

    公开(公告)号：WO2017091272A2

    公开(公告)日：2017-06-01

    申请号：PCT/US2016/050418

    申请日：2016-09-06

    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE

    Inventor： GLAVAN, Ana, C. ,  AINLA, Alar ,  HAMEDI, Mahiar, Max ,  FERNANDEZ-ABEDUL, Maria, Teresa ,  WHITESIDES, George, M.

    IPC: H01L31/0264

    CPC classification number: H01L31/0264 ,  B01L3/502707 ,  B01L3/5088 ,  B01L2200/12 ,  B01L2300/0645 ,  B01L2300/0845 ,  B01L2300/126

    Abstract: An electroanalytical device includes a pin set comprising at least two conductive pins for use as working and counter electrodes, wherein the first and second pins are comprised of a head, a shaft and a piercing tip; and a hydrophobic or omniphobic paper substrate, wherein the substrate is shaped to provide at least one recess for holding a liquid, wherein the shafts of two conductive pins traverse the paper substrate to anchor the heads of the two conductive pins on the recess surface. An electroanalytical device can also include at least two conductive pins for use as working and counter electrodes, a thread, serially wound around the shafts of each of the two conductive pins; and a base into which the piercing tip of each of the pins is secured.

    Abstract translation: 一种电分析装置包括引脚组，该引脚组包括用作工作电极和对电极的至少两个导电引脚，其中第一和第二引脚包括头部，轴和刺穿尖端; 以及疏水性或全向性纸基材，其中所述基材成形为提供用于保持液体的至少一个凹部，其中两个导电针的轴横过所述纸基材以将所述两个导电针的头固定在所述凹部表面上。 电分析装置还可以包括用作工作电极和对电极的至少两个导电引脚，所述导电引脚串联缠绕在两个导电引脚中的每一个的轴上; 以及一个底座，每个销的刺穿尖端固定在该底座中。

    COVER WITH MICRO-CONTAINER INTERFACE FOR COVERING A MICROFLUIDIC GAP
    15.
    发明申请
    COVER WITH MICRO-CONTAINER INTERFACE FOR COVERING A MICROFLUIDIC GAP 审中-公开
    覆盖MICRO-CONID GAP的微型容器接口

    公开(公告)号：WO2017084766A1

    公开(公告)日：2017-05-26

    申请号：PCT/EP2016/052860

    申请日：2016-02-10

    Applicant: TECAN TRADING AG

    Inventor： PERROUD, Thomas ,  HOFFMEYER, Daniel ,  KOPF-SILL, Anne R. ,  SAGER, Adrian

    IPC: B01L3/00

    CPC classification number: B01L3/502707 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502792 ,  B01L3/563 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/0689 ,  B01L2300/047 ,  B01L2300/0645 ,  B01L2300/123 ,  B01L2400/0427 ,  B01L2400/0478

    Abstract: A cover (10) for use in a digital microfluidics system (16) for manipulating samples in liquid portions or droplets is provided. The digital microfluidics system (16) com- prises a first substrate (18) with an array of electrodes (24) and a central control unit (20) for controlling the selection and for providing a number of said electrodes with voltage for manipulating liquid portions or droplets by electrowetting. A working gap (30) with a gap height is located parallel to the array of electrodes (24) and in-between first and second hydrophobic surfaces (26,28) that face each other at least during operation of the digital microfluidics system (16). The cover (10) comprises on one side the second hydrophobic surface (28) and on another side at least one micro-container interface (32), which comprises at least one cone (34). The inner surface of the cone (34) is formed to provide a sealing form fit contact with an outer surface of an inserted micro-container nozzle (36), by which a liquid is transferrable through a fluidic access hole (38) formed into the cover (10) and interconnecting each cone (34) and the gap (30). The cover (10) may be part of a disposable cartridge (14) or may be provided separately.

    Abstract translation: 提供了用于数字微流体系统（16）中用于操纵液体部分或液滴中的样品的盖（10）。 数字微流体系统（16）包括具有电极阵列（24）和中央控制单元（20）的第一基板（18），用于控制选择并向多个所述电极提供用于操纵液体部分 或通过电润湿的液滴。 至少在数字微流体系统（16）的操作过程中，具有间隙高度的工作间隙（30）平行于电极阵列（24）定位并且位于彼此面对的第一和第二疏水表面（26,28）之间 ）。 盖（10）在一侧包括第二疏水表面（28）并且在另一侧包括至少一个微容器接口（32），其包括至少一个锥体（34）。 锥形体（34）的内表面形成为与插入的微容器喷嘴（36）的外表面形成配合接触的密封形式，液体可通过形成于其中的流体通路孔（38） 盖（10）并且互连每个锥体（34）和间隙（30）。 盖（10）可以是一次性盒（14）的一部分或可以单独提供。

    FLUIDIC CARD FOR ANALYSIS OF BIOCHIPS
    16.
    发明申请
    FLUIDIC CARD FOR ANALYSIS OF BIOCHIPS 审中-公开
    流体卡用于分析生物

    公开(公告)号：WO2017072513A1

    公开(公告)日：2017-05-04

    申请号：PCT/GB2016/053341

    申请日：2016-10-27

    Applicant: RANDOX LABORATORIES LTD

    Inventor： JACKSON, Stuart ,  CROCKARD, Martin ,  FITZGERALD, Stephen, Peter ,  LAMONT, John ,  MCCONNELL, Ivan

    IPC: C12Q1/68 ,  B01L3/00

    CPC classification number: C12Q1/6837 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2200/028 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2300/0618 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/0883 ,  B01L2300/0887

    Abstract: A fluidic card assembly comprising a fluidic card housing (1) and a biochip (3) located in the fluidic card housing. The fluidic card housing (1) includes a chamber (2) with a base wall, into which at least one fluidic channel extends. The biochip (3) is at least partially located in the chamber. A seal (7) is provided for sealing the biochip in the chamber (2) when the biochip is urged into the chamber. The fluidic channel has a serpentine form. The seal may be laminated or laser welded to the opening of the chamber in order to provide a window for observing the biochip.

    Abstract translation: 流体卡组件包括流体卡外壳（1）和位于流体卡外壳中的生物芯片（3）。 流体卡外壳（1）包括具有基壁的腔室（2），至少一个流体通道延伸进入该腔室（2）。 生物芯片（3）至少部分地位于腔室中。 提供密封件（7）用于当生物芯片被推入腔室中时密封腔室（2）中的生物芯片。 流体通道具有蛇形形式。 密封件可以层压或激光焊接到室的开口，以提供观察生物芯片的窗口。

    A MICROFLUIDIC DEVICE AND METHODS FOR MANUFACTURING SAME
    17.
    发明申请
    A MICROFLUIDIC DEVICE AND METHODS FOR MANUFACTURING SAME 审中-公开
    一种微流体装置及其制造方法

    公开(公告)号：WO2017031518A1

    公开(公告)日：2017-03-02

    申请号：PCT/AU2015/050484

    申请日：2015-08-21

    Applicant: DEAKIN UNIVERSITY ,  UNIVERSITY OF TASMANIA

    Inventor： GREENE, George W. ,  PAULL, Brett ,  DUFFY, Emer ,  SPILSTEAD, Kara ,  HASWELL, Stephen

    IPC: G01N30/52 ,  B81C1/00 ,  B01D15/08 ,  B01J20/22

    CPC classification number: B01D15/206 ,  B01J20/286 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3251 ,  B01J2220/84 ,  B01J2220/86 ,  B01L3/502707 ,  B01L2300/0816 ,  B01L2300/16 ,  B01L2400/0415 ,  B81C1/00 ,  G01N27/44752 ,  G01N27/44791 ,  G01N30/56 ,  G01N2030/567 ,  G01N30/6095

    Abstract: The present invention relates generally to a sample processing device, such as a microfluidic device, comprising a substrate, wherein the substrate comprises a plurality of channels configured to transport a fluid, and wherein the plurality of channels are substantially coated with lubricin, or a functional variant thereof. Also disclosed herein are methods of manufacturing such devices, methods of preventing fouling of a channel in a device using lubricin, or a functional variant thereof and methods of controlling the electrokinetic flow of an analyte through a channel that is substantially coated with lubricin, or a functional variant thereof. Also disclosed herein is chromatographic material for the electrophoretic and/or chromatographic separation of an analyte, wherein the chromatographic material is substantially coated with lubricin, or a functional variant thereof..

    Abstract translation: 本发明一般涉及一种样品处理装置，例如微流体装置，其包括基底，其中所述基底包括构造成输送流体的多个通道，并且其中所述多个通道基本上涂覆有润滑剂，或功能性 其变体。 还公开了制造这种装置的方法，防止使用润滑剂的装置中的通道的结垢的方法或其功能变体和通过基本上涂有润滑剂的通道控制分析物的电动流动的方法，或 其功能变体。 本文还公开了用于分析物的电泳和/或色谱分离的色谱材料，其中色谱材料基本上涂覆有润滑剂或其功能变体。

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