摘要:
A biological fluids concentration device, including a tube-in-tube assembly, is disclosed. The tube-in-tube assembly receives biologic fluids and may then be placed in the bucket of a centrifuge and spun to separate out the components of the biological fluid by their various densities. For example, whole blood may be centrifuged in the tube-in-tube assembly for separating into plasma, red blood cell component, and a buffy coat. A piston slideably and sealingly engages an inner tube of the tube-in-tube assembly, the inner tube fitting within an outer tube. A lid is designed to engage the top of the outer tube, which lid has an opening therein for receipt of a plunger. The plunger is adapted to move up and down with respect to the lid and the tubes, so as to sealingly, in a down position, and unsealingly, in an open position, engage the top of the inner tube of the tube-in-tube assembly.
摘要:
Example apparatus and methods related to automated diagnostic analyzers having rear accessible track systems. An example apparatus disclosed herein includes an analyzer to perform a diagnostic test, the analyzer having a first side and a second side opposite the first side. The example apparatus includes a loading bay disposed on the first side of the analyzer to receive a first carrier and a pipetting mechanism coupled to the analyzer adjacent the second side. The example apparatus also includes a first carrier shuttle to transport the first carrier from a first location adjacent the loading bay to a second location adjacent the pipetting mechanism and a track disposed adjacent the second side of the analyzer to transfer a second carrier to a third location adjacent the pipetting mechanism.
摘要:
There is provided an automated biological-sample-processing system comprising a pipette, a column of solid-phase material to which nucleic acid binds, a transport apparatus, an air-piston apparatus and an adaptor for coupling the pipette to the transport apparatus and to the air-piston apparatus, in which the adaptor is removably engageable with the transport apparatus and the air-piston apparatus for movement with the transport apparatus during processing of the sample, is couplable to the pipette so that the transport apparatus is controllable to position the pipette and so that the air-piston apparatus is controllable to draw a liquid into the pipette and to expel the liquid from the pipette, and is engageable with the column, in which the adaptor comprises a filter for preventing liquid or aerosol transfer between the pipette or column and the air-piston apparatus.
摘要:
The present invention relates to the automation of incubation, processing, harvesting and analysis of samples (15) in a multi-cell plate (1). In particular, a multi-cell plate (1) comprising a body (3) with a plurality of cells (5) is presented. Furthermore, an automated crystal harvesting and processing system (21) with a cutting unit (23), a fluid unit (29) and a removing device (33) is presented. The multi-cell plate (1) further comprises a sealing film (7) for sealing the cells (5) on a first side (9) of the body (3) and a sample film (11) for sealing the cells (5) on a second side (13) of the body (3). The sample film (11) is adapted for accommodating a biological material (15) for crystallization. Furthermore, the sample film (11) is of a thickness and composition that makes it compatible with x-rays and also with laser ablation. The design of the multi-cell plate (1) and the automated crystal harvesting and processing system (21) allows for several steps of incubation, processing, harvesting and analysis of the samples (15) to be automated.
摘要:
The present invention discloses a section of tubing including a fluoropolmer tubular body which has an interior surface defining a fluid passage through the tubular body. At least a first portion of the interior surface has a first hydrophobicity which is less than that of the remainder of the tubular body. At least a first portion of the interior surface can have a molar ratio of fluorine to oxygen of no greater than 30 to 1. Products can include the tubular bodies of the present invention attachable to fluid processing instruments such as immunodiagnostic instruments. The present invention also discloses methods for manufacturing the disclosed tubular bodies.
摘要:
A robotic end effector for collecting frozen aliquots from an array of frozen samples in a plurality of containers has a coring bit for taking frozen sample cores from the frozen samples and a frozen sample core extraction system adapted to extract frozen sample cores from the frozen samples. A fill level detection system is adapted to detect the positions of the surfaces of the frozen samples. A processor is adapted to receive signals from the fill level detection system and use the signals and information concerning operation of the frozen sample core extraction system to determine at least one of the following: (a) the amount of material contained in a frozen sample core obtained by the coring bit; and (b) the number of frozen sample cores needed from a particular frozen sample to obtain a predetermined amount of material from that frozen sample.
摘要:
Die Erfindung betrifft ein Vorrichtung zur automatisierten Präparation von Zellen für molekularbiologische Untersuchungen, umfassend eine mittels eines Robotsystems (8) bewegliche Entnahmeeinheit (7) zur Entnahme einzelner Zellen oder Zellkolonien (31) aus einem Probenbehälter (3) und Ablage der Zellen oder Zellkolonien (31) an einer vorgegebenen Ablageposition (5, 9), wobei die Entnahmeeinheit (7) mindestens eine Kapillare oder Kanüle (12) zur Aufnahme der einzelnen Zellen oder Zellkolonien (31) aus dem Probenbehälter (3) aufweist. Dabei ist vorgesehen, dass die Kapillare oder Kanüle (12) der Entnahmeeinheit (7) vor der Entnahme einzelner Zellen oder Zellkolonien (31) aus dem Probenbehälter (3) zumindest ein Medium enthält, das ein Vorbereitungsmedium (22, 23, 25), das für eine molekularbiologische Untersuchung der zu entnehmenden Zellen oder Zellkolonien (31) benötigt wird, ist.
摘要:
The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.