公开(公告)号：WO2012034084A3

公开(公告)日：2012-06-28

申请号：PCT/US2011051098

申请日：2011-09-09

Applicant: S E A MEDICAL SYSTEMS INC ,  MATSIEV LEONID F ,  WEICKERT MICHAEL J ,  BENNETT JAMES W ,  SMITH MATTHEW F ,  LITVINTSEVA SVETLANA ,  BLANKE KIT

Inventor： MATSIEV LEONID F ,  WEICKERT MICHAEL J ,  BENNETT JAMES W ,  SMITH MATTHEW F ,  LITVINTSEVA SVETLANA ,  BLANKE KIT

IPC: A61M5/172 ,  G01N27/06 ,  G01N27/08 ,  G01N27/416 ,  G06Q50/00

CPC classification number: G01N27/026 ,  A61M5/142 ,  A61M2205/0244 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/6018 ,  G01N27/4166 ,  Y02A90/26

Abstract: Described herein are devices, systems, and methods for determining the composition of liquids, including the identity of one or more drugs in the liquid, the concentration of the drug, and the type of diluent using immittance spectroscopy. These devices, systems and methods are particularly useful for describing the identity and, in some variations, concentration of one or more components of a medical liquid such as intravenous fluid. In particular, described herein are devices, systems and methods that may operate in low ionic strength diluents. Also described are methods of recognizing complex immittance spectrograph patterns to determine the composition of a liquid by pattern recognition.

Abstract translation: 本文描述了用于确定液体组成的装置，系统和方法，包括液体中一种或多种药物的特性，药物的浓度以及使用导纳光谱法的稀释剂类型。 这些装置，系统和方法对于描述身份以及在一些变型中特别可用于浓缩医疗液体如静脉内液体的一种或多种组分。 特别地，本文描述了可以在低离子强度稀释剂中操作的装置，系统和方法。 还描述了通过模式识别来识别复合导纳光谱仪图案以确定液体的组成的方法。

公开(公告)号：WO2011088462A2

公开(公告)日：2011-07-21

申请号：PCT/US2011021560

申请日：2011-01-18

Applicant: ALBANY MEDICAL COLLEGE ,  ANDERSEN THOMAS T ,  JACOBSON HERBERT I ,  BENNETT JAMES A ,  JOSEPH LEROY ,  BRYAN ALBERTO

Inventor： ANDERSEN THOMAS T ,  JACOBSON HERBERT I ,  BENNETT JAMES A ,  JOSEPH LEROY ,  BRYAN ALBERTO

CPC classification number: C07K14/4715 ,  A61K38/00 ,  C07K7/52 ,  C07K7/64

Abstract: The invention relates to compounds that are analogs of a cyclic peptide, cyclo[EKTOVNOGN], AFPep, that has anti-estrotrophic activity. The analogs of the invention include peptides and petidomimetics that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.

Abstract translation: 本发明涉及作为具有抗雌激素活性的环肽（环[EKTOVNOGN]，AFPep）的类似物的化合物。 本发明的类似物包括抑制雌激素受体依赖性细胞增殖的肽和比模拟物。 本发明的化合物可用于治疗特征在于不希望或不期望的雌激素诱导的细胞增殖（包括乳腺癌）的细胞增殖性病症或生理病症。

公开(公告)号：WO2006127189A3

公开(公告)日：2007-12-06

申请号：PCT/US2006014907

申请日：2006-04-20

Applicant: CONAGRA FOODS INC ,  SUCCAR JORGE K ,  TAVILL GAIL M ,  FOLTA KIM M ,  BENNETT JAMES A

Inventor： SUCCAR JORGE K ,  TAVILL GAIL M ,  FOLTA KIM M ,  BENNETT JAMES A

IPC: A21D10/02 ,  B65D5/50 ,  B65D85/00

CPC classification number: B65D81/3272 ,  A23L23/00 ,  A23V2002/00 ,  B65D81/3227 ,  B65D81/3261 ,  A23V2200/08

Abstract: A container for a liquid-based food item and a packaged liquid-based food item, such as a soup. A container includes an outer member and an inner dividing member that is positioned inside the outer member to define inner and outer cavities. A liquid, such as water or broth, and one or more seasonings are placed in the inner cavity. Particulates, such as meat and vegetable particulates and, if necessary, water, are placed in the outer cavity. Seasonings are separated from particulates, and the seasoning does not diffuse into the particulates. Thus, the tastes of the individual ingredients are maintained. A sealing member extends across a tops of the inner and outer members to close the package. When the sealing member is removed to open the package, the water or broth with the seasoning, and the particulates and any water can be poured from their respective cavities in a single motion. By reducing or eliminating diffusion of seasonings into particulates, reduced quantities of salt and other seasonings can be added to processed soup products and allows salt and other seasonings to be added just prior to cooking, providing more natural flavor. Separating broth and particulates within a container can also reduce sterilization times.

Abstract translation: 用于液体食品的容器和诸如汤的包装液体食品。 容器包括外部构件和内部分隔构件，其位于外部构件内部以限定内部空腔和外部空腔。 将液体如水或肉汤，以及一种或多种调味料置于内腔中。 颗粒如肉和蔬菜颗粒以及必要时的水被放置在外腔中。 调味料与颗粒分离，调味料不会扩散到颗粒中。 因此，保持各种成分的口味。 密封件延伸穿过内部件和外部部件的顶部以封闭包装。 当密封构件被移除以打开包装时，具有调味料的水或肉汤以及颗粒和任何水可以从其各自的空腔以单次运动注入。 通过减少或消除调味料扩散成颗粒物，可以加工少量的盐和其他调味料加工成汤制品，并允许在烹饪之前加入盐和其他调味料，从而提供更自然的风味。 在容器内分离肉汤和颗粒也可以减少灭菌时间。

公开(公告)号：WO2006055278A3

公开(公告)日：2007-06-21

申请号：PCT/US2005040001

申请日：2005-11-02

Applicant: TRADE OF THE CITY OF CHICAGO I ,  ABUSHABAN BASSEL M ,  BENNETT JAMES G ,  BOYLE MICHAEL B ,  DURKIN BRYAN T ,  EAVY RYAN S ,  GILLMORE WILLIAM R ,  KAUFMAN SCOTT R ,  SCHALLER DENISE M

Inventor： ABUSHABAN BASSEL M ,  BENNETT JAMES G ,  BOYLE MICHAEL B ,  DURKIN BRYAN T ,  EAVY RYAN S ,  GILLMORE WILLIAM R ,  KAUFMAN SCOTT R ,  SCHALLER DENISE M

IPC: G06Q40/00

CPC classification number: G06Q40/04

Abstract: A system for reporting and processing a matched trade from a market in response to orders submitted by traders includes a management subsystem for developing configuration data regarding products that are to be traded and traders who are authorized to trade. The system further includes a trade processing subsystem for receiving first data representing the matched trade and which processes the first data to create second data representing a processed trade wherein the second data are transmitted to a first recipient and a reporting subsystem for receiving market information and which processes the market information and transmits the processed market information to a second recipient. Methods of reporting and/or processing are also disclosed.

Abstract translation: 用于根据交易者提交的订单报告和处理来自市场的匹配交易的系统包括用于开发关于要交易的产品和被授权交易的交易者的配置数据的管理子系统。 所述系统还包括交易处理子系统，用于接收表示所述匹配交易的第一数据，并处理所述第一数据以创建表示经处理交易的第二数据，其中所述第二数据被发送到第一接收者和用于接收市场信息的报告子系统以及哪个 处理市场信息并将处理的市场信息传送给第二收件人。 还公开了报告和/或处理方法。

公开(公告)号：WO2007022182A1

公开(公告)日：2007-02-22

申请号：PCT/US2006/031831

申请日：2006-08-15

Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION ,  BENNETT, James, P., Jr.

Inventor： BENNETT, James, P., Jr.

IPC: A61K31/428 ,  A61P25/28

CPC classification number: A61K31/428

Abstract: Formulations and methods of use thereof for restoring neuronal tissue function in children and adults afflicted with chronic neurodegenerative diseases, such as neurodegenerative movement disorders and ataxias, seizure disorders, motor neuron diseases, and inflammatory demyelinating disorders. Examples of disorders include Alzheimer's disease (AD) , Parkinson's disease (PD) , and amyotrophic lateral sclerosis (ALS) . The method involves administering a pharmaceutical composition containing an effective amount of a tetrahydrobenzathiazole, preferably a formulation consisting substantially of the R(+) enantiomer of pramipexole . R(+) pramipexole is generally administered in doses ranging from 0.1-300 mg/kg/daily, preferably 0.5-50 mg/kg/daily, and most preferably 1-10 mg/kg/daily for oral administration. Daily total doses administered orally are typically between 10 mg and 500 mg. Alternatively, R(+) pramipexole can be administered parenterally to humans with acute brain injury in single doses between 10 mg and 100 mg, and/or by continuous intravenous infusions between 10 mg/day and 500 mg/day.

Abstract translation: 用于恢复患有慢性神经变性疾病的儿童和成人的神经元组织功能的制剂及其使用方法，所述慢性神经变性疾病例如神经变性运动障碍和共济失调，癫痫发作障碍，运动神经元疾病和炎性脱髓鞘疾病。 疾病的实例包括阿尔茨海默病（AD），帕金森病（PD）和肌萎缩性侧索硬化症（ALS）。 该方法包括施用含有有效量的四氢苯并噻唑的药物组合物，优选基本上由普拉克索的R（+）对映异构体组成的制剂。 R（+）普拉克索通常以0.1-300mg / kg /日，优选0.5-50mg / kg /日，最优选1-10mg / kg /日的剂量施用于口服给药。 口服给药的每日总剂量通常在10mg至500mg之间。 或者，R（+）普拉克索可以以10mg至100mg的单次剂量和/或连续静脉内输注10mg /天至500mg /天肠胃外给予患有急性脑损伤的人。

公开(公告)号：WO2006084263A2

公开(公告)日：2006-08-10

申请号：PCT/US2006/004231

申请日：2006-02-03

Applicant: SYMYX TECHNOLOGIES, INC. ,  KOLOSOV, Oleg ,  SPITKOVSKY, Mikhail ,  BENNETT, James ,  MATSEIV, Leonid ,  GAMMER, Vladimir

Inventor： KOLOSOV, Oleg ,  SPITKOVSKY, Mikhail ,  BENNETT, James ,  MATSEIV, Leonid ,  GAMMER, Vladimir

IPC: G01N29/02 ,  G01N29/036 ,  G01H13/00 ,  G01N29/22 ,  G01F23/296

CPC classification number: G01F23/2967 ,  G01F23/2966 ,  G01H13/00 ,  G01N29/022 ,  G01N29/036 ,  G01N29/22 ,  G01N2291/0226 ,  G01N2291/02818 ,  G01N2291/02836 ,  G01N2291/0422 ,  G01N2291/0423 ,  G01N2291/0426 ,  G01N2291/0427 ,  G01N2291/106 ,  H01R13/65807

Abstract: Fluid monitoring methods, sensors and systems are disclosed. Preferred embodiments comprise two or more mechanical resonators, preferably two or more flexural resonators configured for sensing, monitoring or evaluating one or more fluids at multiple positions within one or more fluidic systems. In the methods, sensors and systems of the invention, signals generated in response to stimulation of the mechanical resonators are communicated by multiplexing over a common communication path, and then deconvoluted with respect to the position of the resonators.

Abstract translation: 公开了流体监测方法，传感器和系统。 优选实施例包括两个或更多个机械谐振器，优选地，两个或更多个弯曲谐振器被配置为感测，监测或评估一个或多个流体系统内的多个位置处的一个或多个流体。 在这些方法中，本发明的传感器和系统响应于机械谐振器的刺激而产生的信号通过在公共通信路径上进行复用来传送，然后相对于谐振器的位置解卷积。

公开(公告)号：WO2002031477A2

公开(公告)日：2002-04-18

申请号：PCT/US2001/031710

申请日：2001-10-10

Applicant: SYMYX TECHNOLOGIES, INC. ,  KUEBLER, Sigrid, C. ,  BENNETT, James

Inventor： KUEBLER, Sigrid, C. ,  BENNETT, James

IPC: G01N21/49

CPC classification number: B01D15/08 ,  B01D15/26 ,  B01D15/265 ,  B01D15/325 ,  B01D15/34 ,  B01J19/0046 ,  B01J19/26 ,  B01J2219/00274 ,  B01J2219/00315 ,  B01J2219/00585 ,  B01J2219/00587 ,  B01J2219/00707 ,  B01J2219/00722 ,  C40B40/14 ,  C40B60/14 ,  G01N15/0205 ,  G01N21/253 ,  G01N21/51 ,  G01N21/532 ,  G01N30/02 ,  G01N30/16 ,  G01N30/24 ,  G01N30/30 ,  G01N30/461 ,  G01N30/466 ,  G01N30/54 ,  G01N30/60 ,  G01N30/6052 ,  G01N30/88 ,  G01N33/44 ,  G01N33/442 ,  G01N35/085 ,  G01N35/1097 ,  G01N2015/0288 ,  G01N2015/0294 ,  G01N2030/324 ,  G01N2030/625

Abstract: Methods, systems and devices are described for rapid characterization and screening of liquid samples to determine properties (e.g., particle size, particle size distribution, molar mass and/or molar mass distribution) thereof with static light scattering and/or dynamic light scattering. The liquid samples can be solutions, emulsions, suspensions or dispersions. One method, includes providing a vessel containing a liquid sample having an exposed surface that defines a gas-liquid sample interface, and analyzing the sample by light scattering methods that include transmitting light through the gas-liquid sample interface into the sample, and detecting light scattered from the sample or from a component thereof. Additional methods are directed to characterizing a plurality of liquid samples or components thereof. The methods, systems, and devices have applications in high-throughput screening, and particularly, in combinatorial materials research and in industrial process control.

Abstract translation: 描述了用于快速表征和筛选液体样品以确定静态光散射和/或动态光散射的性质（例如，粒度，粒度分布，摩尔质量和/或摩尔质量分布）的方法，系统和装置。 液体样品可以是溶液，乳液，悬浮液或分散体。 一种方法包括提供容器，该容器含有具有限定气 - 液样品界面的暴露表面的液体样品，并通过光散射方法分析样品，所述光散射方法包括通过气 - 液样品界面将光透射到样品中，以及检测光 从样品或其组分散射。 额外的方法涉及表征多个液体样品或其组分。 方法，系统和设备在高通量筛选中具有应用，特别是在组合材料研究和工业过程控制中。

公开(公告)号：WO2012158637A1

公开(公告)日：2012-11-22

申请号：PCT/US2012/037823

申请日：2012-05-14

Applicant: LIGHTWEDGE LLC ,  BENNETT, James F.

Inventor： BENNETT, James F.

IPC: A45C11/00 ,  A45C13/00 ,  G06F1/16 ,  H04B1/38

CPC classification number: A45C11/00 ,  A45C13/005 ,  A45C2011/003 ,  B65D5/5206 ,  F16M11/10 ,  F16M11/38 ,  F16M13/00 ,  G06F1/166 ,  Y10T29/49815

Abstract: An apparatus for protecting an electronic device includes a first protective cover component and a second protective component that may be removably coupled to one another. The second protective cover component includes a hinge component having a flexible hinge portion extending from a peripheral portion of the second protective cover component, wherein the hinge component facilitates coupling of the second protective cover component to the first protective cover component. One of the first protective cover component and the second protective cover component include a region configured to receive the electronic device

Abstract translation: 一种用于保护电子装置的装置包括第一保护盖部件和可彼此可拆卸地联接的第二保护部件。 第二保护盖部件包括铰链部件，铰链部件具有从第二保护盖部件的周边部分延伸的柔性铰链部分，其中铰链部件便于将第二保护盖部件联接到第一保护盖部件。 第一保护盖部件和第二保护盖部件中的一个包括构造成接收电子设备的区域

公开(公告)号：WO2011088462A3

公开(公告)日：2011-07-21

申请号：PCT/US2011/021560

申请日：2011-01-18

Applicant: ALBANY MEDICAL COLLEGE ,  ANDERSEN, Thomas, T. ,  JACOBSON, Herbert I. ,  BENNETT, James A. ,  JOSEPH, Leroy ,  BRYAN, Alberto

Inventor： ANDERSEN, Thomas, T. ,  JACOBSON, Herbert I. ,  BENNETT, James A. ,  JOSEPH, Leroy ,  BRYAN, Alberto

IPC: C07K7/52 ,  A61K38/12 ,  A61P35/00

Abstract: The invention relates to compounds that are analogs of a cyclic peptide, cyclo [EKTOVNOGN], AFPep, that has anti-estrotrophic activity. The analogs of the invention include peptides and petidomimetics that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.

公开(公告)号：WO2010144482A2

公开(公告)日：2010-12-16

申请号：PCT/US2010/037817

申请日：2010-06-08

Applicant: S.E.A. MEDICAL SYSTEMS, INC. ,  MATSIEV, Leonid ,  WEICKERT, Michael ,  BENNETT, James

Inventor： MATSIEV, Leonid ,  WEICKERT, Michael ,  BENNETT, James

IPC: G01N27/06 ,  G01N27/02 ,  G01N33/15

CPC classification number: A61B5/145 ,  A61B5/14557 ,  A61B5/4839 ,  A61B5/7267 ,  A61M5/172 ,  A61M2205/3523 ,  A61M2205/3592 ,  G01N27/026

Abstract: Described herein are devices, systems, and methods for determining the composition of fluids, and particularly for describing the identity and concentration of one or more components of a medical fluid such as intravenous fluid. These devices, systems and methods take multiple complex admittance measurements from a fluid sample in order to identify the identity and the concentration of components of the fluid. The identity and concentration of all of the components of the solution may be simultaneously and rapidly determined. In some variations, additional measurement or sensing modalities may be used in addition to admittance spectroscopy, including optical, thermal, chemical, etc.

Abstract translation: 本文描述了用于确定流体组成的装置，系统和方法，特别是用于描述诸如静脉内流体的医用流体的一种或多种组分的特性和浓度。 这些装置，系统和方法从流体样品进行多重复杂的导纳测量，以便识别流体组分的特性和浓度。 可以同时快速地确定溶液的所有组分的特性和浓度。 在一些变型中，除导纳光谱外，还可以使用额外的测量或感测方式，包括光学，热学，化学等。