公开(公告)号：WO2006096161A8

公开(公告)日：2007-10-25

申请号：PCT/US2005006924

申请日：2005-03-03

Applicant: MANNATECH INC ,  MCANALLEY BILL H ,  VENNUM EILEEN ,  MCANALLEY SHAYNE A ,  KOEPKE C MICHAEL ,  EDWARDS JOSH

Inventor： MCANALLEY BILL H ,  VENNUM EILEEN ,  MCANALLEY SHAYNE A ,  KOEPKE C MICHAEL ,  EDWARDS JOSH

IPC: A61K9/22

CPC classification number: A23L33/105 ,  A23P10/28 ,  A23P10/30 ,  A23V2002/00 ,  A23V2200/02 ,  A23V2250/21166 ,  A23V2250/51 ,  A23V2250/21168

Abstract: The present invention relates to the modified release of nutritional supplements by combining one or more isolated and purified long-chain polysaccharides and one or more nutritional supplements selected from anti-oxidants, vitamins, minerals, amino acids, nucleic acids, mixtures and combinations thereof, wherein the supplement is compressed at a pressure greater that 100 psi.

Abstract translation: 本发明涉及通过组合一种或多种分离和纯化的长链多糖和选自抗氧化剂，维生素，矿物质，氨基酸，核酸，混合物和组合的一种或多种营养补充剂的营养补充剂的改变释放， 其中所述补充物在高于100psi的压力下被压缩。

公开(公告)号：WO2006112958A8

公开(公告)日：2007-10-11

申请号：PCT/US2006007699

申请日：2006-03-02

Applicant: MANNATECH INC ,  MCANALLEY BILL H ,  VENNUM EILEEN ,  MCANALLEY SHAYNE A ,  KOEPKE MICHAEL C ,  EDWARDS JOSH

Inventor： MCANALLEY BILL H ,  VENNUM EILEEN ,  MCANALLEY SHAYNE A ,  KOEPKE MICHAEL C ,  EDWARDS JOSH

IPC: A61K9/22 ,  A23K1/175 ,  A23L1/00 ,  A23L1/22 ,  A23L1/30 ,  A61K36/00

CPC classification number: A23K20/00 ,  A23K20/20 ,  A23K40/20 ,  A23L27/72 ,  A23L33/10 ,  A23L33/105 ,  A23L33/145 ,  A23L33/15 ,  A23L33/175 ,  A23P10/30

Abstract: The present invention relates to the modified release of nutritional supplements by combining one or more isolated and purified long-chain polysaccharides and one or more nutritional supplements selected from anti-oxidants, vitamins, minerals, amino acids, nucleic acids, mixtures and combinations thereof, wherein the supplement is compressed at a pressure greater that 100 psi.

Abstract translation: 本发明涉及通过组合一种或多种分离和纯化的长链多糖和选自抗氧化剂，维生素，矿物质，氨基酸，核酸，其混合物和组合的一种或多种营养补充剂来调节营养补充剂的释放， 其中补充物在大于100psi的压力下被压缩。

公开(公告)号：WO1998006418A1

公开(公告)日：1998-02-19

申请号：PCT/US1997013379

申请日：1997-08-04

Applicant: MANNATECH, INC. ,  McANALLEY, Bill, H. ,  McDANIEL, H., Reginald ,  MOORE, D., Eric ,  VENNUM, Eileen, P. ,  FIORETTI, William, C.

Inventor： MANNATECH, INC.

IPC: A61K38/16

CPC classification number: A23L33/11 ,  A23L5/00 ,  A23L19/03 ,  A23L21/00 ,  A23L29/231 ,  A23L29/238 ,  A23L29/244 ,  A23L29/25 ,  A23L29/256 ,  A23L29/262 ,  A23L29/27 ,  A23L29/273 ,  A23L29/275 ,  A23L29/30 ,  A23L33/105 ,  A23L33/125 ,  A23V2002/00 ,  A23V2250/506 ,  A23V2250/5084 ,  A23V2250/5056 ,  A23V2250/503 ,  A23V2250/608 ,  A23V2250/61 ,  A23V2250/618 ,  A23V2250/638 ,  A23V2250/1578 ,  A23V2250/2102 ,  A23V2250/5118 ,  A23V2250/308

Abstract: Compositions of plant carbohydrates for dietary supplements and nutritional support for promotion and maintenance of good health. Defined nutritionally effective amounts of one to eleven essential saccharides, glyconutrients, are used in various inventive compositions as dietary supplements. The dietary composition herein can include phytonutrients, vitamins, minerals, herbal extracts, and other non-toxic nutrients. The glyconutritional dietary supplement herein provides essential saccharides which are the building blocks of glycoproteins. These compositions, when administered orally or topically, have been found to improve the well being of mammals suffering from a variety of disorders.

Abstract translation: 植物碳水化合物用于膳食补充剂和营养支持的组合，用于促进和维持良好的健康。 定义的营养有效量的一至十一种必需糖，糖类营养素，用于各种本发明组合物中作为膳食补充剂。 本文的饮食组合物可以包括植物营养素，维生素，矿物质，草药提取物和其它无毒营养物质。 本发明的糖营养膳食补充剂提供作为糖蛋白的结构单元的必需糖类。 已经发现，当口服或局部给药时，这些组合物可改善患有多种疾病的哺乳动物的健康。

公开(公告)号：WO2005022116A9

公开(公告)日：2005-11-10

申请号：PCT/US2004027644

申请日：2004-08-25

Applicant: MANNATECH INC ,  MCANALLEY BILL H ,  VENNUM EILEEN P ,  MCANALLEY SHAYNE A ,  KOEPKE MICHAEL C

Inventor： MCANALLEY BILL H ,  VENNUM EILEEN P ,  MCANALLEY SHAYNE A ,  KOEPKE MICHAEL C

IPC: A61K31/353 ,  A61K31/355 ,  A61K31/7048 ,  A61K36/24 ,  A61K36/82 ,  A61K36/87 ,  G01N21/64

CPC classification number: A61K31/355 ,  A61K31/353 ,  A61K31/7048 ,  A61K36/24 ,  A61K36/82 ,  A61K36/87 ,  G01N33/1806 ,  Y10S514/904 ,  Y10T436/142222 ,  A61K2300/00

Abstract: The present invention includes an apparatus and method for detecting directly the antioxidant activity of both lipophobic anti-oxidants that uses an oxygen radical sensitive sensor in fluid communication with a sample in a solvent/water/surfactant mixture; wherein the oxygen radical sensitive sensor concurrently detects both lipophilic and lipophobic anti-oxidants in the solvent/water/surfactant mixture.

Abstract translation: 本发明包括一种用于直接检测在溶剂/水/表面活性剂混合物中与样品流体连通的氧自由基敏感传感器的抗脂肪抗氧化剂的抗氧化活性的装置和方法; 其中氧自由基敏感传感器同时检测溶剂/水/表面活性剂混合物中的亲脂性和疏脂性抗氧化剂。

公开(公告)号：WO2005022116A2

公开(公告)日：2005-03-10

申请号：PCT/US2004027644

申请日：2004-08-25

Applicant: MANNATECH INC ,  MCANALLEY BILL H ,  VENNUM EILEEN P ,  MCANALLEY SHAYNE A ,  KOEPKE MICHAEL C

Inventor： MCANALLEY BILL H ,  VENNUM EILEEN P ,  MCANALLEY SHAYNE A ,  KOEPKE MICHAEL C

IPC: A61K31/353 ,  A61K31/355 ,  A61K31/7048 ,  A61K36/24 ,  A61K36/82 ,  A61K36/87 ,  G01N

CPC classification number: A61K31/355 ,  A61K31/353 ,  A61K31/7048 ,  A61K36/24 ,  A61K36/82 ,  A61K36/87 ,  G01N33/1806 ,  Y10S514/904 ,  Y10T436/142222 ,  A61K2300/00

Abstract: The present invention includes an apparatus and method for detecting directly the antioxidant activity of both lipophobic anti-oxidants that uses an oxygen radical sensitive sensor in fluid communication with a sample in a solvent/water/surfactant mixture; wherein the oxygen radical sensitive sensor concurrently detects both lipophilic and lipophobic anti-oxidants in the solvent/water/surfactant mixture.

Abstract translation: 本发明包括用于直接检测使用与溶剂/水/表面活性剂混合物中的样品流体连通的氧自由基敏感传感器的两种疏脂性抗氧化剂的抗氧化剂活性的装置和方法; 其中氧自由基敏感传感器同时检测溶剂/水/表面活性剂混合物中的亲脂性和疏脂性抗氧化剂。

公开(公告)号：WO2017023356A1

公开(公告)日：2017-02-09

申请号：PCT/US2016/000064

申请日：2016-08-04

Applicant: MCANALLEY, Bill H.

Inventor： MCANALLEY, Bill H. ,  MCANALLEY, MD, Shayne ,  AGUAYO, Erik H.

IPC: A61K47/00

CPC classification number: A61K31/7004 ,  A23L1/09 ,  A23L1/30 ,  A23L33/10 ,  A23L33/105 ,  A23L33/125 ,  A23L33/21 ,  A23V2002/00 ,  A61K31/715 ,  A61K2300/00

Abstract: This invention clearly identifies the current agriculture-based diseases facing United States citizens such as, heart disease, stroke, cancer, diabetes and other degenerative diseases that did not exist in our hunter-gatherer ancestors. The United States government has established the Dietary Guidelines Advisory Committee (DGAC) to solve the problem. The DGAC's approach includes exercise, better agricultural based food choices plus vitamins-mineral supplements that are sex and age adjusted. We designed supplement compositions composed of unmodified dried fruits, herbs, including roots and tubers, many of which contain a lot of phytoestrogens. Currently, the medical profession has a bias against phytoestrogens, based on science that we believe is incorrectly interpreted. Today, women are afraid of getting breast cancer, and men are afraid of getting enlarged breasts from phytoestrogens. We will reinterpret the pre-clinical medical studies to alleviate these accepted concerns. Our supplement ingredients are chosen based on the different apoptosis pathways, which they stimulate, modulate or inhibit.

Abstract translation: 本发明清楚地确定了目前在美国公民面临的基于农业的疾病，如心脏病，中风，癌症，糖尿病和其他退化性疾病，在我们的狩猎采集者祖先中不存在。 美国政府已经建立了膳食指南咨询委员会（DGAC）来解决问题。 DGAC的方法包括运动，更好的农业基础食品选择以及性别和年龄调整的维生素 - 矿物质补充剂。 我们设计了由未修改的干果，草药，包括根和块茎组成的补充剂，其中许多含有大量的植物雌激素。 目前，医学界对植物雌激素具有偏见，基于我们认为不正确解释的科学。 今天，妇女害怕患乳腺癌，男人害怕从植物雌激素中增加乳房。 我们将重新解释临床前的医学研究，以减轻这些被接受的担忧。 我们的补充成分是基于不同的凋亡途径，它们刺激，调节或抑制的。

公开(公告)号：WO2006112958A3

公开(公告)日：2007-11-29

申请号：PCT/US2006007699

申请日：2006-03-02

Applicant: MANNATECH INC ,  MCANALLEY BILL H ,  VENNUM EILEEN ,  MCANALLEY SHAYNE A ,  KOEPKE MICHAEL C ,  EDWARDS JOSH

Inventor： MCANALLEY BILL H ,  VENNUM EILEEN ,  MCANALLEY SHAYNE A ,  KOEPKE MICHAEL C ,  EDWARDS JOSH

IPC: A61K9/22 ,  A23K1/175 ,  A23L1/00 ,  A23L1/22 ,  A23L1/30 ,  A61K36/00

CPC classification number: A23K20/00 ,  A23K20/20 ,  A23K40/20 ,  A23L27/72 ,  A23L33/10 ,  A23L33/105 ,  A23L33/145 ,  A23L33/15 ,  A23L33/175 ,  A23P10/30

Abstract: The present invention relates to the modified release of nutritional supplements by combining one or more isolated and purified long-chain polysaccharides and one or more nutritional supplements selected from anti-oxidants, vitamins, minerals, amino acids, nucleic acids, mixtures and combinations thereof, wherein the supplement is compressed at a pressure greater that 100 psi.

公开(公告)号：WO2006112958A2

公开(公告)日：2006-10-26

申请号：PCT/US2006/007699

申请日：2006-03-02

Applicant: MANNATECH, INC. ,  MCANALLEY, Bill, H. ,  VENNUM, Eileen ,  MCANALLEY, Shayne, A. ,  KOEKE, Michael, C. ,  EDWARDS, Josh

Inventor： MCANALLEY, Bill, H. ,  VENNUM, Eileen ,  MCANALLEY, Shayne, A. ,  KOEKE, Michael, C. ,  EDWARDS, Josh

IPC: A23K1/175

CPC classification number: A23K20/00 ,  A23K20/20 ,  A23K40/20 ,  A23L27/72 ,  A23L33/10 ,  A23L33/105 ,  A23L33/145 ,  A23L33/15 ,  A23L33/175 ,  A23P10/30

Abstract: The present invention relates to the modified release of nutritional supplements by combining one or more isolated and purified long-chain polysaccharides and one or more nutritional supplements selected from anti-oxidants, vitamins, minerals, amino acids, nucleic acids, mixtures and combinations thereof, wherein the supplement is compressed at a pressure greater that 100 psi.

Abstract translation: 本发明涉及通过组合一种或多种分离和纯化的长链多糖和选自抗氧化剂，维生素，矿物质，氨基酸，核酸，其混合物和组合的一种或多种营养补充剂来调节营养补充剂的释放， 其中补充物在大于100psi的压力下被压缩。

公开(公告)号：WO2006096161A1

公开(公告)日：2006-09-14

申请号：PCT/US2005/006924

申请日：2005-03-03

Applicant: MANNATECH, INC. ,  McANALLEY, Bill, H. ,  VENNUM, Eileen ,  McANALLEY, Shayne, A. ,  KOEPKE, C., Michael ,  EDWARDS, Josh

Inventor： McANALLEY, Bill, H. ,  VENNUM, Eileen ,  McANALLEY, Shayne, A. ,  KOEPKE, C., Michael ,  EDWARDS, Josh

IPC: A61K9/22

CPC classification number: A23L33/105 ,  A23P10/28 ,  A23P10/30 ,  A23V2002/00 ,  A23V2200/02 ,  A23V2250/21166 ,  A23V2250/51 ,  A23V2250/21168

Abstract: The present invention relates to the modified release of nutritional supplements by combining one or more isolated and purified long-chain polysaccharides and one or more nutritional supplements selected from anti-oxidants, vitamins, minerals, amino acids, nucleic acids, mixtures and combinations thereof, wherein the supplement is compressed at a pressure greater that 100 psi.

Abstract translation: 本发明涉及通过组合一种或多种分离和纯化的长链多糖和选自抗氧化剂，维生素，矿物质，氨基酸，核酸，其混合物和组合的一种或多种营养补充剂来调节营养补充剂的释放， 其中补充物在大于100psi的压力下被压缩。

公开(公告)号：WO2005022116A3

公开(公告)日：2005-03-10

申请号：PCT/US2004/027644

申请日：2004-08-25

Applicant: MANNATECH, INC. ,  MCANALLEY, Bill, H. ,  VENNUM, Eileen, P. ,  MCANALLEY, Shayne, A. ,  KOEPKE, Michael, C.

Inventor： MCANALLEY, Bill, H. ,  VENNUM, Eileen, P. ,  MCANALLEY, Shayne, A. ,  KOEPKE, Michael, C.

IPC: G01N21/64

Abstract: The present invention includes an apparatus and method for detecting directly the antioxidant activity of both lipophobic anti-oxidants that uses an oxygen radical sensitive sensor in fluid communication with a sample in a solvent/water/surfactant mixture; wherein the oxygen radical sensitive sensor concurrently detects both lipophilic and lipophobic anti-oxidants in the solvent/water/surfactant mixture.