公开(公告)号：WO2010041230A2

公开(公告)日：2010-04-15

申请号：PCT/IB2009055206

申请日：2009-10-12

Applicant: CNRS DAE ,  INST CURIE ,  UNIV PARIS CURIE ,  UNIV PARIS SUD XI ,  VIOVY JEAN-LOUIS ,  LE NEL ANNE

Inventor： VIOVY JEAN-LOUIS ,  LE NEL ANNE

IPC: G01N33/50

CPC classification number: G01N33/54333 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2400/043 ,  B03C1/01 ,  B03C1/288 ,  B03C2201/20 ,  B03C2201/26

Abstract: An integrated microsystem, comprising: a microchannel, a field generator to create a magnetic field in at least one first portion of the microchannel having a direction substantially collinear with the direction of flow in the portion of the microchannel, the magnetic field also presenting a gradient, wherein the microsystem additionally comprises a detection area in fluid connection with the microchannel.

Abstract translation: 一种集成微系统，包括：微通道，场发生器，用于在所述微通道的至少一个第一部分中产生具有与所述微通道的所述部分中的流动方向基本共线的方向的磁场，所述磁场还呈现梯度 ，其中所述微系统还包括与所述微通道流体连接的检测区域。

公开(公告)号：WO2005024007A8

公开(公告)日：2005-05-20

申请号：PCT/FR2004002257

申请日：2004-09-06

Applicant: CENTRE NAT RECH SCIENT ,  UNIV PARIS SUD XI ,  GUILHOT CHRISTOPHE ,  DAFFE MAMADOU ,  HOUSSIN CHRISTINE ,  PORTEVIN DAMIEN ,  DE SOUSA CELIA

Inventor： GUILHOT CHRISTOPHE ,  DAFFE MAMADOU ,  HOUSSIN CHRISTINE ,  PORTEVIN DAMIEN ,  DE SOUSA CELIA

IPC: C12N9/10 ,  C12N15/54 ,  G01N33/50

CPC classification number: C12N9/1029 ,  C12N2310/111

Abstract: The invention relates to a novel enzyme involved in the biosynthesis of mycolic acids and to the use thereof for the screening of antibiotics, especially antimycobacterials. The invention more particularly relates to the Pks13 protein which catalyzes Claisen condensation or malonic condensation in mycolates between an acyl-CoA molecule or an acyl-AMP molecule and an acylmalonyl-CoA molecule to form an intermediate ß-cEto acyl ou ß-cEto ester.

Abstract translation: 本发明涉及涉及霉菌酸生物合成的新型酶及其用于筛选抗生素，特别是抗分支杆菌的用途。 本发明更具体地涉及Pech13蛋白，其催化酰基-CoA分子或酰基-GAA分子与酰基丙二酰基-CoA分子之间的非晶体结构中的Claisen缩合或丙二酸缩合以形成中间体β-cEto酰基ω-cE酯。

公开(公告)号：WO2004087622A3

公开(公告)日：2004-11-18

申请号：PCT/EP2004004132

申请日：2004-04-02

Applicant: INST NAT SANTE RECH MED ,  UNIV PARIS DESCARTES ,  UNIV PARIS SUD XI ,  DE ROUX NICOLAS ,  GENIN EMMANUELLE ,  MILGROM EDWIN ,  CHAUSSAIN JEAN-LOUIS ,  CAREL JEAN-CLAUDE

Inventor： DE ROUX NICOLAS ,  GENIN EMMANUELLE ,  MILGROM EDWIN ,  CHAUSSAIN JEAN-LOUIS ,  CAREL JEAN-CLAUDE

IPC: C07K14/47 ,  C07K14/72

CPC classification number: C07K14/4702

Abstract: The invention provides an agonist or antagonist of the GPR54 receptor for its use for treating a gonadotropin related disorder; a ligand of the GPR54 receptor for its use for diagnosing a subject's gonadotropin abnormality; a method for screening a compound that affect the gonadotropic axis comprising the step of assaying the compound in the presence of a GPR54 receptor and novel proteins useful in the above.

Abstract translation: 本发明提供GPR54受体的激动剂或拮抗剂，用于治疗促性腺激素相关病症; 用于诊断受试者促性腺激素异常的GPR54受体的配体; 用于筛选影响促性腺轴的化合物的方法，包括在GPR54受体的存在下测定化合物和在上述中有用的新蛋白质的步骤。

公开(公告)号：WO2004005593A3

公开(公告)日：2004-04-08

申请号：PCT/FR0302093

申请日：2003-07-04

Applicant: COMMISSARIAT ENERGIE ATOMIQUE ,  UNIV PARIS SUD XI ,  D ANGELO MARIE ,  ARISTOV VICTOR ,  SOUKIASSIAN PATRICK

Inventor： D ANGELO MARIE ,  ARISTOV VICTOR ,  SOUKIASSIAN PATRICK

IPC: B82B1/00 ,  B82B3/00 ,  C23C14/04 ,  C30B23/00 ,  C30B33/00 ,  H01L21/04 ,  H01L29/04 ,  H01L29/06 ,  H01L29/15 ,  H01L29/24 ,  H01L21/02 ,  H01L51/20

CPC classification number: C23C14/04 ,  B82Y10/00 ,  B82Y30/00 ,  C30B23/00 ,  C30B29/02 ,  C30B29/605 ,  C30B33/00 ,  H01L21/0445 ,  H01L29/045 ,  H01L29/1608

Abstract: The invention concerns metal nano-objects, formed on semiconductor surfaces, and a method for making said nano-objects. The invention is applicable in nanoelectronics for example to obtain nano-objects (4) by deposition of a metal on a prepared cubic SiC surface (2).

Abstract translation: 本发明涉及在半导体表面上形成的金属纳米物体，以及制造所述纳米物体的方法。 本发明可用于纳米电子学，例如通过在制备的立方SiC表面（2）上沉积金属来获得纳米物体（4）。

公开(公告)号：WO2005095442A8

公开(公告)日：2006-11-02

申请号：PCT/EP2005003339

申请日：2005-03-30

Applicant: ROUSSY INST GUSTAVE ,  CENTRE NAT RECH SCIENT ,  UNIV PARIS SUD XI ,  RENARD MARTIAL ,  MANGENEY MARIANNE ,  HEIDMANN THIERRY

Inventor： RENARD MARTIAL ,  MANGENEY MARIANNE ,  HEIDMANN THIERRY

IPC: A61K38/08 ,  A61K38/10 ,  A61K39/00 ,  C07K7/06 ,  C07K7/08 ,  C12N5/00 ,  C12N7/00 ,  C12N7/04 ,  C12N15/63 ,  C12N15/86

CPC classification number: C07K7/08 ,  C07K7/06

Abstract: The present invention relates to a polypeptide having a sequence of 7 to 20 amino acid residues, which is capable of modulating the immunosuppressive properties of a viral protein or a fragment thereof, against the host in which it is expressed (immunosuppression-modulatory sequence) when it substitutes the homologous sequence of said viral protein or fragment, said polypeptide comprising the minimum following consensus amino acid sequence: X 1 Y 9 Y 10 Y 11 CY 12 X 2 wherein, X 1 and X 2 are selected to impact on said immunosuppressive properties, and Y 9 to Y 12 represent variable amino acid residues.

Abstract translation: 本发明涉及具有7至20个氨基酸残基的序列的多肽，其能够调节其表达的宿主（免疫抑制调节序列）的病毒蛋白或其片段的免疫抑制性质（免疫抑制调节序列） 它代替所述病毒蛋白或片段的同源序列，所述多肽包含最小的以下共有氨基酸序列：X 1 Y Y Y Y 其中，选择X 1和X 2，其中X 1，X 2，X 2，X 2， 以影响所述免疫抑制性质，Y 9至Y 12代表可变氨基酸残基。

公开(公告)号：WO2005012276A2

公开(公告)日：2005-02-10

申请号：PCT/FR2004002049

申请日：2004-07-30

Applicant: CENTRE NAT RECH SCIENT ,  UNIV PARIS SUD XI ,  BONNET-DELPON DANIELE ,  BEGUE JEAN-PIERRE ,  CROUSSE BENOIT ,  MAGUEUR GUILLAUME

Inventor： BONNET-DELPON DANIELE ,  BEGUE JEAN-PIERRE ,  CROUSSE BENOIT ,  MAGUEUR GUILLAUME

IPC: A61K31/335 ,  A61P31/18 ,  A61P33/06 ,  C07D303/36

CPC classification number: C07D303/36 ,  A61K31/335 ,  Y02P20/55

Abstract: The invention relates to compounds of general formula (I) wherein R represents H or an amine-function protective group such as a benzyl group which is substituted or not, a phenyl group which is substituted or not such as paramethoxy phenyl, or a phenyl group substituted by a group of the formula CH(Ph)CH2-OCH3 (R or S).

Abstract translation: 本发明涉及通式（I）的化合物，其中R代表H或胺官能团保护基如被取代或未被取代的苄基，被取代或未被取代的苯基如对甲氧基苯基或苯基 被式CH（Ph）CH 2 -OCH 3（R或S）的基团取代。

公开(公告)号：WO2015165809A3

公开(公告)日：2015-12-30

申请号：PCT/EP2015058873

申请日：2015-04-24

Applicant: CENTRE NAT RECH SCIENT ,  UNIV NANTES ,  UNIV PARIS SUD XI

Inventor： CARIO LAURENT ,  CORRAZE BENOIT ,  STOLIAR PABLO ,  TRANCHANT JULIEN ,  JANOD ETIENNE ,  BESLAND MARIE-PAULE ,  ROZENBERG MARCELO

IPC: G06N3/063 ,  G06N3/04 ,  G11C11/54

CPC classification number: G06N3/063 ,  G06N3/049 ,  G06N3/0635 ,  G11C11/54 ,  G11C13/0002 ,  H01L45/1253 ,  H01L45/14 ,  H01L45/16

Abstract: The invention relates to an artificial neuron (30) consisting of a single-component electric dipole comprising a single material (31) which belongs to the class of Mott insulators and is connected to two electric electrodes (32, 33).

Abstract translation: 本发明涉及一种由单组分电偶极组成的人造神经元（30），其包括属于莫特绝缘子类的单一材料（31），并连接到两个电极（32,33）。

公开(公告)号：WO2010125252A3

公开(公告)日：2010-12-23

申请号：PCT/FR2010000328

申请日：2010-04-23

Applicant: CENTRE NAT RECH SCIENT ,  UNIV PARIS SUD XI ,  LU YU-WEI

Inventor： LU YU-WEI

IPC: B01J27/188 ,  B01J23/652 ,  B01J23/89 ,  B01J31/18 ,  B01J35/00 ,  B01J37/02 ,  C01B32/50 ,  C25B11/04 ,  C25B11/12 ,  H01M4/92

CPC classification number: H01M4/92 ,  B01J23/6527 ,  B01J23/687 ,  B01J23/8993 ,  B01J27/188 ,  B01J31/1815 ,  B01J35/0033 ,  B01J37/0219 ,  B01J2531/828 ,  C01B32/50 ,  C07C29/48 ,  H01M4/8652 ,  H01M4/8657 ,  H01M4/8807 ,  H01M4/8828 ,  H01M4/8842 ,  H01M4/886 ,  H01M4/90 ,  H01M4/9008 ,  H01M4/923 ,  H01M8/08 ,  H01M2250/20 ,  H01M2250/30 ,  Y02B90/18 ,  Y02P70/56 ,  Y02T90/32

Abstract: The invention relates to a catalyst, to the use thereof for the electrochemical conversion of methane to methanol and for the direct electrochemical conversion of methane to CO2. The invention also relates to an electrode, in particular for a fuel cell including such a catalyst, as well as to a method for manufacturing such an electrode. The invention further relates to a fuel cell including said catalyst or said electrode. The catalyst according to the invention includes a platinum precursor (II), and optionally a metal-ion precursor M supported by particles of a heteropolyanion (HPA). The invention can be used in particular in the field of the electrochemical oxidation of methane into methanol or CO2.

Abstract translation: 本发明涉及一种催化剂，用于将甲烷电化学转化成甲醇和将甲烷直接电化学转化成二氧化碳。 本发明还涉及电极，特别是用于包括这种催化剂的燃料电池，以及制造这种电极的方法。 本发明还涉及包括所述催化剂或所述电极的燃料电池。 根据本发明的催化剂包括铂前体（II）和任选的由杂多阴离子（HPA）颗粒负载的金属离子前体M. 本发明特别可用于将甲烷电化学氧化成甲醇或二氧化碳的领域。

公开(公告)号：WO2004061095A3

公开(公告)日：2004-09-23

申请号：PCT/FR0303751

申请日：2003-12-16

Applicant: CENTRE NAT RECH SCIENT ,  UNIV PARIS SUD XI ,  VIROLLE MARIE-JOELLE ,  GHORBEL SAFIANE ,  GERBAUD CLAUDE

Inventor： VIROLLE MARIE-JOELLE ,  GHORBEL SAFIANE ,  GERBAUD CLAUDE

IPC: C12N15/31 ,  C12N15/52 ,  C12N15/74 ,  C12P19/60 ,  C12N9/12 ,  C12N15/76 ,  C12P17/16

CPC classification number: C12N15/74 ,  C12N15/52 ,  C12P19/60

Abstract: The invention relates to the use of micro-organism strains producing useful compounds provided with an inactive phoR/phoP operon for carrying out a method for stimulating the production of said useful compounds by means of said transformed strains.

Abstract translation: 本发明涉及生产提供有无活性phoR / phoP操纵子的有用化合物的微生物菌株用于实施通过所述转化菌株刺激所述有用化合物产生的方法。