Patent search ap:"XIA Page Yi"

1.

发明申请
TECHNOLOGIES FOR ISOLATED HEAT DISSIPATING DEVICES 审中-公开

公开(公告)号：WO2022187986A1

公开(公告)日：2022-09-15

申请号：PCT/CN2021/079425

申请日：2021-03-06

Applicant: INTEL CORPORATION , SUBRAHMANYAM, Prabhakar , CHAO, Tong Wa , PANG, Ying-Feng , XIA, Yi , MOHAMMED, Rahima, K. , POLYANKO, Victor, P. , SAHAN, Ridvan, A. , ZHANG, Guangying , YING, Guoliang , WANG, Chuanlou , LU, Jun , DU, Liguang , WEI, Peng , QUE, Xiang

Inventor： SUBRAHMANYAM, Prabhakar , CHAO, Tong Wa , PANG, Ying-Feng , XIA, Yi , MOHAMMED, Rahima, K. , POLYANKO, Victor, P. , SAHAN, Ridvan, A. , ZHANG, Guangying , YING, Guoliang , WANG, Chuanlou , LU, Jun , DU, Liguang , WEI, Peng , QUE, Xiang

IPC: H01L23/427 , G06F1/20

Abstract: Techniques for heat sinks and cold plates for compute systems are disclosed. In one embodiment, a heat sink includes two sub-heat sinks that are mechanically connected but thermally isolated. The two sub-heat sinks can independently cool different dies on the same integrated circuit component. In another embodiment, a system includes an integrated circuit component that is cooled by a first water block and a second water block. The first water block forms a loop with a gap in it, and the second water block has a pedestal that extends through the gap in the first water block to contact the integrated circuit component. The first water block and the second water block can independently cool different dies on the same integrated circuit component.

2.

发明申请
BORON-CONTAINING SMALL MOLECULES 审中-公开
Title translation: 含硼小分子

公开(公告)号：WO2017151489A1

公开(公告)日：2017-09-08

申请号：PCT/US2017/019650

申请日：2017-02-27

Applicant: ANACOR PHARMACEUTICALS, INC. , BILL AND MELINDA GATES FOUNDATION , LI, Xianfeng , LUNDE, Christopher, S. , JACOBS, Robert, T. , HERNANDEZ, Vincent, S. , XIA, Yi , PLATTNER, Jacob, J. , CAO, Kathy, Jingyuan , ZHANG, Yong-kang , Perry, Matthew

Inventor： LI, Xianfeng , LUNDE, Christopher, S. , JACOBS, Robert, T. , HERNANDEZ, Vincent, S. , XIA, Yi , PLATTNER, Jacob, J. , CAO, Kathy, Jingyuan

IPC: A61K31/69 , A61K31/215 , A61P31/04

Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.

Abstract translation: 公开了治疗细菌感染的化合物，药物制剂和方法。

3.

发明申请
TRISUBSTITUTED BORON-CONTAINING MOLECULES 审中-公开
Title translation: 含有分子量的含硼分子

公开(公告)号：WO2011017125A1

公开(公告)日：2011-02-10

申请号：PCT/US2010/043437

申请日：2010-07-27

Applicant: ANACOR PHARMACEUTICALS, INC. , GLAXOSMITHKINE LLC , XIA, Yi , ALLEY, Michael, Richard Kevin , ZHOU, Yasheen , SINGH, Rajeshwar , DING, Charles , CAO, Kathy , PLATTNER, Jacob, J. , OU, Ligong , JIA, Guofeng , SARASWAT, Neerja , RAMACHANDRAN, Sreekanth , ZHOU, Ding

Inventor： XIA, Yi , ALLEY, Michael, Richard Kevin , ZHOU, Yasheen , SINGH, Rajeshwar , DING, Charles , CAO, Kathy , PLATTNER, Jacob, J. , OU, Ligong , JIA, Guofeng , SARASWAT, Neerja , RAMACHANDRAN, Sreekanth , ZHOU, Ding

IPC: A01N55/08 , C07F5/02 , A62D3/36 , A61P31/04 , A01P1/00 , A61K31/69

CPC classification number: C07F5/025 , A61K31/69 , A61K45/06 , A61K2300/00

Abstract: This invention largely relates to 3,4,6-trisubstituted benzoxaborole compounds, and their use for treating bacterial infections.

Abstract translation: 本发明主要涉及3,4,6-三取代苯并恶唑化合物及其用于治疗细菌感染的用途。

4.

发明申请
SUBSTITUTED PYRAZOLE AND TRIAZOLE COMPOUNDS AS KSP INHIBITORS 审中-公开
Title translation: 取代的吡唑和三唑化合物作为KSP抑制剂

公开(公告)号：WO2008063912A1

公开(公告)日：2008-05-29

申请号：PCT/US2007/084154

申请日：2007-11-08

Applicant: NOVARTIS AG , XIA, Yi , MENDENHALL, Kris G. , BARSANTI, Paul A. , WALTER, Annette O. , DUHL, David , RENHOWE, Paul A.

Inventor： XIA, Yi , MENDENHALL, Kris G. , BARSANTI, Paul A. , WALTER, Annette O. , DUHL, David , RENHOWE, Paul A.

IPC: C07D249/08 , C07D401/12 , C07D403/12 , C07D413/12 , A61K31/55 , A61P35/00

CPC classification number: C07D401/12 , C07D249/08 , C07D403/12 , C07D413/12

Abstract: Disclosed are new substituted pyrazole and triazole compounds of Formula (I) and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the derivatives together with pharmaceutically acceptable carriers, and uses thereof:

Abstract translation: 公开了式（I）的新的取代的吡唑和三唑化合物及其药学上可接受的盐，酯或前药，衍生物的组合物和药学上可接受的载体，及其用途：

5.

发明申请
2-AMINO-QUINAZ0LIN-5-ONES AS HSP90 INHIBITORS USEFUL IN TREATING PROLIFERATION DISEASES 审中-公开
Title translation: 2-AMINO-QUINAZ0LIN-5-ONES作为HSP90抑制剂用于治疗增殖性疾病

公开(公告)号：WO2006113498A3

公开(公告)日：2007-01-11

申请号：PCT/US2006014194

申请日：2006-04-14

Applicant: CHIRON CORP , MACHAJEWSKI TIMOTHY D , GAO ZHENHAI , LEVINE BARRY H , ANTONIOS-MCCREA WILLIAM , BELLAMACINA CORNELIA R , COSTALES ABRAN , DOUGHAN BRANDON M , FONG SUSAN , HENDRICKSON THOMAS , LIN XIAODONG , MCBRIDE CHRISTOPHER , MCKENNA MAUREEN , RICO ALICE C , SHAFER CYNTHIA M , WANG X MICHAEL , ZHOU YASHEEN , XIA YI , MENDENHALL KRIS G

Inventor： MACHAJEWSKI TIMOTHY D , GAO ZHENHAI , LEVINE BARRY H , ANTONIOS-MCCREA WILLIAM , BELLAMACINA CORNELIA R , COSTALES ABRAN , DOUGHAN BRANDON M , FONG SUSAN , HENDRICKSON THOMAS , LIN XIAODONG , MCBRIDE CHRISTOPHER , MCKENNA MAUREEN , RICO ALICE C , SHAFER CYNTHIA M , WANG X MICHAEL , ZHOU YASHEEN , XIA YI , MENDENHALL KRIS G

IPC: C07D239/84 , A61K31/517 , A61P35/00 , C07D401/04 , C07D401/10 , C07D403/04 , C07D403/10 , C07D403/12 , C07D413/10 , C07D417/10 , C07D417/12

CPC classification number: C07D401/14 , C07D239/84 , C07D401/04 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/10 , C07D403/12 , C07D409/10 , C07D413/10 , C07D417/10 , C07D417/12 , C07D417/14

Abstract: 2-Amino-quinazolin-5-one compounds, stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cell proliferative diseases.

Abstract translation: 2-氨基 - 喹唑啉-5-酮化合物，立体异构体，互变异构体，其药学上可接受的盐和前药; 包括药学上可接受的载体和一种或多种2-氨基 - 喹唑啉-5-酮化合物的组合物，单独或与至少一种另外的治疗剂组合。单独使用2-氨基 - 喹唑啉-5-酮化合物或与至少一种其它治疗剂组合使用的方法用于预防或治疗细胞增殖性疾病。

6.

发明申请
TETRAHYDROCARBOLINE COMPOUNDS AS ANTICANCER AGENTS 审中-公开
Title translation: 四氯化碳化合物作为反应剂

公开(公告)号：WO2005070930A3

公开(公告)日：2006-01-19

申请号：PCT/US2005002270

申请日：2005-01-24

Applicant: CHIRON CORP , WANG WEIBO , NI ZHI-JIE , BARSANTI PAUL , PECCHI SABINA , XIA YI , BRAMMEIER NATHAN , TREUTLE MEGAN , JAZAN ELISA , WAYMAN KELLY , DIBBLE DAVID , CHENG JIE-KAI

Inventor： WANG WEIBO , NI ZHI-JIE , BARSANTI PAUL , PECCHI SABINA , XIA YI , BRAMMEIER NATHAN , TREUTLE MEGAN , JAZAN ELISA , WAYMAN KELLY , DIBBLE DAVID , CHENG JIE-KAI

IPC: A61K31/4745 , C07D471/02 , C07D471/04 , A61K31/437

CPC classification number: C07D471/04

Abstract: Tetrahydrocarboline compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.

Abstract translation: 四氢咔啉化合物，其药学上可接受的盐和前药; 包括药学上可接受的载体和一种或多种四氢咔啉化合物的组合物，单独或与至少一种其它治疗剂组合。单独使用四氢咔啉化合物或与至少一种另外的治疗剂组合使用的方法可用于预防或治疗增殖性疾病。

7.

发明申请
GRAM-POSITIVE BACTERIA SPECIFIC BINDING COMPOUNDS 审中-公开
Title translation: 格兰氏阳性细菌特异性结合化合物

公开(公告)号：WO2011008092A2

公开(公告)日：2011-01-20

申请号：PCT/NL2010050456

申请日：2010-07-15

Applicant: AIMM THERAPEUTICS BV , GENENTECH INC , BEAUMONT TIM , KWAKKENBOS MARK JEROEN , BROWN ERIC J , MORISAKI JOHN HIROSHI , HAZENBOS WOUTER L W , MARIATHASAN SANJEEV , KAJIHARA KIMBERLY , XIA YI

Inventor： BEAUMONT TIM , KWAKKENBOS MARK JEROEN , BROWN ERIC J , MORISAKI JOHN HIROSHI , HAZENBOS WOUTER L W , MARIATHASAN SANJEEV , KAJIHARA KIMBERLY , XIA YI

IPC: C07K16/12

CPC classification number: C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/5091 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26

Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.

Abstract translation: 本发明提供了能够特异性结合革兰氏阳性菌的改进的结合化合物。提供的完整人类结合化合物使得能够在人类个体中进行治疗应用。