公开(公告)号：WO2012097311A3

公开(公告)日：2012-10-04

申请号：PCT/US2012021335

申请日：2012-01-13

Applicant: ABBOTT LAB ,  VON OEPEN RANDOLF ,  EHRENREICH KEVIN J

Inventor： VON OEPEN RANDOLF ,  EHRENREICH KEVIN J

IPC: A61F2/24 ,  A61F2/86

CPC classification number: A61F2/2475 ,  A61F2/86 ,  A61F2210/009 ,  A61F2230/0058 ,  A61F2230/0076

Abstract: Intraluminal scaffold assembly implantable in a body lumen of a patient to manipulate a valve of the lumen is provided. The intraluminal scaffold assembly includes an intraluminal scaffold (1100), an elongated core member (1200) coupled with the intraluminal scaffold having a length sufficient to traverse a valve in a body lumen with the intraluminal scaffold positioned proximate the valve. The intraluminal scaffold assembly can further include one or more additional intraluminal scaffolds, a weighted element (1201) or an active element that is coupled with the elongated core member. A system including a delivery system and the intraluminal scaffold assembly, as well as methods of delivering the intraluminal scaffold assembly and using the intraluminal scaffold assembly to manipulate a valve in a body lumen, is also provided.

Abstract translation: 提供可植入患者的体腔中以操纵管腔的瓣膜的腔内支架组件。 管腔内支架组件包括管腔内支架（1100），与管腔内支架联接的细长芯构件（1200），其长度足以穿过体腔内的瓣膜，腔内支架位于瓣膜附近。 管腔内支架组件还可以包括一个或多个附加的管腔内支架，加权元件（1201）或与细长芯构件联接的有源元件。 还提供了包括递送系统和管腔内支架组件的系统，以及递送管腔内支架组件和使用管腔内支架组件来操纵体腔中的瓣膜的方法。

公开(公告)号：WO2010111124A3

公开(公告)日：2010-11-18

申请号：PCT/US2010027878

申请日：2010-03-18

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS ,  MAGANA JESUS ,  VON OEPEN RANDOLF ,  WEBLER JR WILLIAM E ,  BRADSHAW ALLAN ,  EHRENREICH KEVIN J

Inventor： MAGANA JESUS ,  VON OEPEN RANDOLF ,  WEBLER JR WILLIAM E ,  BRADSHAW ALLAN ,  EHRENREICH KEVIN J

IPC: A61F2/958 ,  B24C1/04 ,  B26F1/00 ,  B29C49/00

CPC classification number: A61M25/1027 ,  A61M25/007 ,  A61M25/1006 ,  A61M2025/0057 ,  A61M2025/1031 ,  A61M2025/105 ,  A61M2025/1061 ,  A61M2025/1086 ,  B23K26/382 ,  B23K2201/04 ,  B23K2203/42 ,  B23K2203/50 ,  B24C1/045 ,  B26F1/31 ,  B29C49/00 ,  B29C49/08 ,  B29C67/0018 ,  B29C2049/0089 ,  B29C2793/0045 ,  B29K2027/06 ,  B29K2067/00 ,  B29K2105/258 ,  B29L2031/7542

Abstract: A porous balloon (14) or other catheter structure is formed by creating specific size pores (24) for delivering an agent to a body lumen (18). The pores can be created by passing matter or energy through the surface of the catheter structure, as by a laser (35) or a projectile (51). In the case of laser, the catheter structure can be reversed so that the inner surface becomes the outer surface to convert diverging pores into converging pores. In the case of projectiles, a pore size can be achieved by selecting an appropriate size and shaped projectile to obtain the desired characteristic. Alternatively, a material to make the catheter structure can include impurities (29,59) that can be removed once the catheter structure is set, leaving pores where the material formed around the impurities.

Abstract translation: 通过产生用于将药剂递送到体腔（18）的特定尺寸的孔（24）来形成多孔气囊（14）或其它导管结构。 可以通过将物质或能量通过导管结构的表面，如激光（35）或射弹（51）来产生孔。 在激光的情况下，导管结构可以反转，使得内表面变成外表面，以将发散的孔转化成会聚的孔。 在弹丸的情况下，可以通过选择合适的尺寸和成形的抛射体来获得孔径，以获得所需的特性。 或者，用于制造导管结构的材料可以包括杂质（29,59），其可以在导管结构设置后被去除，留下在杂质周围形成材料的孔。

公开(公告)号：WO2009076215A2

公开(公告)日：2009-06-18

申请号：PCT/US2008085702

申请日：2008-12-05

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS ,  NGUYEN BINH T ,  VON OEPEN RANDOLF ,  EHRENREICH KEVIN J ,  WEBLER WILLIAM E ,  MIN SUNG WOO ,  LUMAUIG ROMMEL ,  YRIBARREN TRAVIS R

Inventor： NGUYEN BINH T ,  VON OEPEN RANDOLF ,  EHRENREICH KEVIN J ,  WEBLER WILLIAM E ,  MIN SUNG WOO ,  LUMAUIG ROMMEL ,  YRIBARREN TRAVIS R

IPC: A61M25/04 ,  A61F2/958

CPC classification number: A61M25/0155 ,  A61M25/0013 ,  A61M25/0068 ,  A61M25/008 ,  A61M25/0082 ,  A61M25/0084 ,  A61M25/04 ,  A61M25/0606 ,  A61M25/1002 ,  A61M25/1011 ,  A61M2025/0081 ,  A61M2025/0092 ,  A61M2025/0096 ,  A61M2025/0681 ,  A61M2025/1047

Abstract: An agent delivery catheter having two or more axially spaced balloons and an inflation bridge providing fluid communication between the two balloons. The catheter generally has a proximal balloon, a distal balloon, and a tube defining an inflation bridge lumen which is located in part within the inflatable interiors of the balloons, and which extends therebetween, and which has a proximal port within the proximal balloon interior and a distal port within the distal balloon interior to thereby provide for inflation of the distal balloon by placing the distal balloon interior in fluid communication with the proximal balloon interior of the shaft.

Abstract translation: 具有两个或更多个轴向间隔的气球的药剂递送导管和提供两个气囊之间的流体连通的充气桥。 导管通常具有近端球囊，远端球囊和限定膨胀桥腔的管，管腔部分地位于气囊的可充气内部之间，并且在气囊内部延伸，并且在近端球囊内部具有近端口， 远侧气囊内部的远端口，从而通过将远端球囊内部与轴的近端球囊内部流体连通来提供远端球囊的膨胀。

公开(公告)号：WO2011137372A9

公开(公告)日：2011-12-22

申请号：PCT/US2011034621

申请日：2011-04-29

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS ,  EHRENREICH KEVIN J ,  MAGANA JESUS ,  CONSIGNY PAUL

Inventor： EHRENREICH KEVIN J ,  MAGANA JESUS ,  CONSIGNY PAUL

IPC: A61M25/10 ,  A61F2/84 ,  A61M29/02

CPC classification number: A61M25/10181 ,  A61M25/0021 ,  A61M25/0032 ,  A61M25/10 ,  A61M25/1002 ,  A61M25/1018 ,  A61M25/10185 ,  A61M25/10186 ,  A61M25/10187 ,  A61M25/104 ,  A61M2025/004 ,  A61M2025/105 ,  A61M2025/1075 ,  A61M2025/1086

Abstract: A catheter capable of rapid inflation and deflation and operation by one individual.

Abstract translation: 导管能够通过一个人快速通气和通气和操作。

公开(公告)号：WO2006063335A3

公开(公告)日：2009-04-16

申请号：PCT/US2005044880

申请日：2005-12-12

Applicant: ARRYX INC ,  PLEWA JOSEPH S ,  TANNER EVAN B ,  MUETH DANIEL M ,  DUKE CRYSTAL J ,  EHRENREICH KEVIN J

Inventor： PLEWA JOSEPH S ,  TANNER EVAN B ,  MUETH DANIEL M ,  DUKE CRYSTAL J ,  EHRENREICH KEVIN J

IPC: G01N33/48 ,  G06G7/48

CPC classification number: G02B21/32 ,  B01L3/502761 ,  G01N1/34 ,  G01N15/1463 ,  G01N2001/007 ,  G01N2015/1454 ,  G01N2015/149 ,  G02B5/32 ,  Y10T436/25375

Abstract: An apparatus and method for purifying a forensic sample using an automated extraction and purification system includes optical tweezers; an input channel through which the sample is introduced; a chamber which receives the sample from the input channel; a collection channel through which selected particles of the sample are removed; and an output through which unselected particles of the sample are removed. At least one buffer input channel is provided. The input channel may allow sedimentation of the sample into the chamber by gravity. In another arrangement, the system includes an optical trapping system; a first channel through which the sample is introduced; a second channel through which buffer is introduced; wherein the optical tweezers are used to move selected particles of the sample from the first channel to the second channel. The selected particles may be sperm. The optical tweezers preferably utilize holographic optical trapping.

Abstract translation: 使用自动提取和净化系统来净化法医样品的装置和方法包括光学镊子; 导入样品的输入通道; 从输入通道接收样品的室; 取出样品的所选粒子的收集通道; 以及去除样品的未选择的颗粒的输出。 提供至少一个缓冲器输入通道。 输入通道可以允许样品通过重力沉降到室中。 在另一种布置中，该系统包括光学捕获系统; 引入样品的第一通道; 引入缓冲液的第二通道; 其中所述光学镊子用于将所述样品的选定颗粒从所述第一通道移动到所述第二通道。 所选择的颗粒可能是精子。 光学镊子优选利用全息光学捕获。