公开(公告)号：WO2023086940A1

公开(公告)日：2023-05-19

申请号：PCT/US2022/079717

申请日：2022-11-11

申请人： BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE SA

发明人： ENERIO, Jeshrene Renee ,  MENSING, Elizabeth Ashley ,  OPPEGARD, Shawn Collin ,  CHEN, Nicole Alexandra ,  MISHRA, Arvind ,  WELLINGS, Anders ,  SWANSON, Leah ,  ZANNI, Richard ,  CIANCIOLO, Joan Angela ,  DELCASTILLO, Jorge Augusto ,  MULLER, Matthew ,  PADMANI, Bhavesh ,  SHYAM, Vishnu ,  GUSTAFSON, Sven ,  LINDHULT, Mikael ,  BORGQVIST, Per-Olof ,  DRENNAN, Peter ,  HOLMER, Mattias

IPC分类号： A61B5/00 ,  A61M1/16 ,  A61M1/28 ,  G16H20/17 ,  G16H40/63 ,  A61B5/16 ,  G16H20/40 ,  G16H20/70 ,  G16H50/20 ,  G16H50/50

摘要： A peritoneal dialysis system includes a control unit configured to (i) store a sleep state pattern for the patient, (ii) begin a patient drain followed by a patient fill when at least one sensor indicates that the patient is in a deep sleep state, (iii) extend a dwell period if the sleep state pattern indicates that the patient will enter a subsequent deep sleep state within a first time duration after a programmed dwell period, and (iv) shorten the dwell period if the sleep state pattern indicates that the patient will leave the deep sleep state within a second time duration after an end of the programmed dwell period. The system alternatively or additionally assesses or records a stress level of and/or a fluid/caloric intake by the patient and takes actions accordingly.

公开(公告)号：WO2021242851A1

公开(公告)日：2021-12-02

申请号：PCT/US2021/034235

申请日：2021-05-26

申请人： BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE SA

发明人： MULLER, Matthew ,  WESTBERG, Tom ,  KENDALL, James W. ,  CORRALES, Carlos ,  CARPANI, Michela ,  ROVATTI, Paolo ,  VINCI, Luca ,  SUFFRITTI, Mauro

IPC分类号： A61M1/16 ,  A61M1/28 ,  A61L2/20

摘要： A mobile dialysis therapy cart includes a top shelf; a cycler compartment positioned below the top shelf, the cycler compartment sized and shaped to house an APD cycler; a fluid bag management compartment sized and shaped to house at least two fluid bags; a drain compartment positioned below the fluid bag management compartment; and a plurality of wheels. The cart may include a heating device associated with the fluid bag management compartment and/or a sanitizing light source for sanitizing a location of a disposable set associated with the fluid bags.

公开(公告)号：WO2017142693A1

公开(公告)日：2017-08-24

申请号：PCT/US2017/015322

申请日：2017-01-27

申请人： BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE SA

发明人： PERRY, Mark ,  DELCASTILLO, Jorge ,  MULLER, Matthew ,  CORRALES, Carlos ,  YARDIMCI, Atif ,  LAIRD, James

IPC分类号： A61M1/36 ,  A61M5/36 ,  B01D19/00

CPC分类号： A61M1/1658 ,  A61M1/28 ,  A61M1/3486 ,  A61M1/3627 ,  A61M1/3638 ,  A61M1/3679 ,  A61M5/36 ,  A61M5/385 ,  A61M2205/123 ,  A61M2205/7536 ,  A61M2206/16 ,  B01D19/0057

摘要： An airtrap for a medical or physiological fluid in one embodiment includes a conical housing having a radius that increases from its top to its bottom when the housing is positioned for operation; a medical or physiological fluid inlet located at an upper portion of the conical housing; a medical or physiological fluid outlet located at a lower portion of the conical housing, the inlet and the outlet positioned and arranged so that medical or physiological fluid spirals in an increasing arc around an inside of the conical housing downwardly from the inlet to the outlet; and a gas collection area located at an upper portion of the conical housing. In another embodiment, the airtrap is shaped like a seahorse having a head section and a tail section. Any of the airtraps herein may be used for example in blood sets, peritoneal dialysis cassette tubing, and drug delivery sets.

摘要翻译： 在一个实施例中，用于医疗或生理流体的空气囊包括圆锥形壳体，当壳体被定位用于操作时，圆锥形壳体具有从其顶部到其底部增大的圆锥形壳体; 位于圆锥形壳体的上部的医疗或生理流体入口; 位于圆锥形壳体下部的医疗或生理流体出口，入口和出口被定位和布置成使得医疗或生理流体围绕圆锥形壳体内部从入口到出口向下以增加的弧度螺旋形地旋转; 以及位于圆锥形壳体上部的气体收集区域。 在另一个实施例中，空气囊形状像具有头部和尾部的海马。 本文中的任何气室可用于例如血液组，腹膜透析盒管和药物递送组。

公开(公告)号：WO2004037377A1

公开(公告)日：2004-05-06

申请号：PCT/US2003/033311

申请日：2003-10-21

申请人： BAXTER INTERNATIONAL INC.

发明人： MULLER, Matthew

IPC分类号： B01D21/26

CPC分类号： A61M1/3693 ,  A61M1/0236 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3612 ,  A61M1/3633 ,  A61M1/3696 ,  A61M1/38 ,  A61M2202/0429 ,  A61M2205/125 ,  A61M2205/128 ,  A61M2205/331 ,  B01D17/0217 ,  B01D21/262 ,  B01D2221/08 ,  B01D2221/10 ,  B04B5/0442 ,  B04B13/00 ,  B04B2005/045

摘要： Processing systems and methods comprise a separation device that, in use, performs a separation process including separation of red blood cells from blood or a suspension containing red blood cells. The systems and methods include an outlet line (104) coupled to the separation device to remove red blood cells from the separation device, at least in part, while the separation process occurs. A sensor (148) associated with the outlet line (104) senses hematocrit of red blood cells removed from the separation device and generates a sensed hematocrit output. A controller is coupled to the separation device to control removal of red blood cells from the separation device based, at least in part, upon the sensed hematocrit.

摘要翻译： 加工系统和方法包括分离装置，其在使用中进行包括从血液中分离红细胞的分离过程或含有红细胞的悬浮液。 该系统和方法包括连接到分离装置的出口管线（104），以在分离过程发生时至少部分地从分离装置移除红细胞。 与出口管线（104）相关联的传感器（148）感测从分离装置移除的红细胞的血细胞比容并产生感测的血细胞比容输出。 控制器耦合到分离装置，以至少部分地基于感测的血细胞比容来控制从分离装置中去除红细胞。

公开(公告)号：WO2009055301A1

公开(公告)日：2009-04-30

申请号：PCT/US2008/080166

申请日：2008-10-16

申请人： BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  ROHDE, Justin ,  MULLER, Matthew ,  BRAUN, Alexander

发明人： ROHDE, Justin ,  MULLER, Matthew ,  BRAUN, Alexander

IPC分类号： A61M1/36

CPC分类号： A61M1/3643 ,  A61M1/288 ,  A61M1/3644 ,  A61M1/3649 ,  A61M1/365 ,  A61M1/3652 ,  A61M2205/12

摘要： A renal treatment fluid priming method includes priming an extracorporeal circuit (30) connected to a patient with a physiologically compatible fluid, the extracorporeal circuit including an arterial line, a venous line and blood compartment of a blood filter (34); and pumping from a renal treatment fluid line in communication with the blood filter (i) pulling blood from the patient through the arterial line to flush the physiologically compatible fluid through the arterial line and the blood filter compartment into the renal treatment fluid line and (ii) pulling blood from the patient through the venous line to flush the physiologically compatible fluid through the venous line and the blood filter compartment into the renal treatment fluid line, such that a greater volume of blood is pulled from the patient via (i) and (ii) than a volume of the extracorporeal circuit.

摘要翻译： 肾脏治疗液引发方法包括用生理相容的流体引导连接到患者的体外循环（30），所述体外回路包括血液过滤器（34）的动脉线，静脉线和血液隔室; 以及从与所述血液过滤器连通的肾脏治疗流体管线泵送（i）从患者通过所述动脉线抽吸血液，以将生理上相容的流体通过所述动脉线路和所述血液过滤器室冲洗成肾脏治疗流体管线，并且 ）通过静脉管线从患者抽出血液以将生理上相容的流体通过静脉管线和血液过滤器隔室冲洗到肾脏治疗流体管线中，从而通过（i）和（i）和（i）从患者中提取更多体积的血液， ii）比一个体积的体外电路。

公开(公告)号：WO2009055302A4

公开(公告)日：2009-04-30

申请号：PCT/US2008/080175

申请日：2008-10-16

申请人： BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  MULLER, Matthew ,  BUSBY, Donald ,  ROHDE, Justin ,  JABLONSKI, Mark

发明人： MULLER, Matthew ,  BUSBY, Donald ,  ROHDE, Justin ,  JABLONSKI, Mark

IPC分类号： A61M1/16 ,  G01F1/704

摘要： A dialysis system includes a dialyzer (34); a blood pump (18c) coupled operably to a dialyzer; a dialysate inlet pump (18a) coupled operably to a dialysate inlet of the dialyzer; a dialysate outlet pump (18b) coupled operably to a dialysate outlet of the dialyzer; a first non-invasive fluid velocity sensor (40a) positioned to sensor of inlet flowrate of dialysate pumped to the dialysate inlet by the dialysate inlet pump; and a second non-invasive fluid velocity sensor (40b) positioned to sense an outlet flowrate of dialysate pumped from the dialysate outlet by the dialysate outlet pump.

公开(公告)号：WO2012122016A1

公开(公告)日：2012-09-13

申请号：PCT/US2012/027476

申请日：2012-03-02

申请人： BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  CHEN, Ye ,  DING, Yuanpang Samuel ,  MULLER, Matthew ,  NAJDENI, Gert ,  TITUS, Joel

发明人： CHEN, Ye ,  DING, Yuanpang Samuel ,  MULLER, Matthew ,  NAJDENI, Gert ,  TITUS, Joel

IPC分类号： G01F23/284 ,  A61M1/16

CPC分类号： A61M5/1684 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1605 ,  A61M1/1607 ,  A61M1/1668 ,  A61M1/28 ,  A61M1/287 ,  A61M5/14 ,  A61M5/1407 ,  A61M5/1409 ,  A61M5/142 ,  A61M2205/3317 ,  A61M2205/3379 ,  A61M2205/3389 ,  A61M2205/52 ,  G01F22/00 ,  G01F23/26 ,  G01F23/263 ,  G01F23/284

摘要： A medical fluid system includes a medical fluid pump; a container holding a fluid to be pumped by the medical fluid pump, the fluid at a first time having a first conductivity, the fluid at a second time having a second conductivity; and a radio frequency level sensor positioned in operable relation with the container, the radio frequency operation of the level sensor configured so as to be (i) indicative of a level of the fluid in the container and (ii) at least substantially independent of whether the fluid has the first conductivity or the second conductivity. The medical fluid system can determine the level of medical fluid by measuring the resistance, impedance or phase shift seen by the sensor.

摘要翻译： 医疗流体系统包括医疗流体泵; 容纳待由所述医用流体泵泵送的流体的容器，所述流体第一时间具有第一导电性，所述第二时间的流体具有第二导电性; 以及射频水平传感器，所述射频水平传感器定位在与所述容器可操作的关系中，所述水平传感器的射频操作被配置为（i）指示所述容器中的流体水平，以及（ii）至少基本上不依赖于 流体具有第一导电性或第二导电性。 医用液体系统可以通过测量传感器看到的电阻，阻抗或相移来确定药液的液位。

公开(公告)号：WO2012122018A4

公开(公告)日：2012-09-13

申请号：PCT/US2012/027478

申请日：2012-03-02

申请人： BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  CHEN, Ye ,  DING, Yuanpang Samuel ,  MULLER, Matthew ,  NAJDENI, Gert ,  TITUS, Joel

发明人： CHEN, Ye ,  DING, Yuanpang Samuel ,  MULLER, Matthew ,  NAJDENI, Gert ,  TITUS, Joel

IPC分类号： G01F23/284 ,  A61M1/16

摘要： A medical fluid system includes a medical fluid pump; a container holding a fluid to be pumped by the medical fluid pump, the fluid at a first time having a first conductivity, the fluid at a second time having a second conductivity; and a radio frequency level sensor positioned in operable relation with the container, the radio frequency operation of the level sensor configured so as to be (i) indicative of a level of the fluid in the container and (ii) at least substantially independent of whether the fluid has the first conductivity or the second conductivity. The medical fluid system can determine the level of medical fluid by measuring the resistance, impedance or phase shift seen by the sensor.

公开(公告)号：WO2004037375A1

公开(公告)日：2004-05-06

申请号：PCT/US2003/033471

申请日：2003-10-21

申请人： BAXTER INTERNATIONAL INC.

发明人： MULLER, Matthew ,  ODAK, Sanjay

IPC分类号： B01D17/12

CPC分类号： B01D17/12

摘要： An optical sensing assembly (46) is adapted for use in association with a separation device having a separation zone associated with umbilicus (100) in which red blood cells and plasma are separated from blood. The assembly (46) comprises a controllercommunicating with and having different, selectable functions for operating first optical sensing unit (506A, 508A) associated with a red blood cell outlet path (104) that removes red blood cells. The controller also communicates with a second optical sensing unit (506B, 508B) associated with a plasma outlet path (106) for removing plasma.

摘要翻译： 光学感测组件（46）适于与具有与脐带（100）相关联的分离区域的分离装置结合使用，其中红细胞和血浆与血液分离。 组件（46）包括与第一光学感测单元（506A，508A）连接并具有不同的可选择功能的控制器，该第一光学感测单元（506A，508A）与去除红细胞的红细胞出口路径相关联。 控制器还与与等离子体出口路径（106）相关联的用于去除等离子体的第二光学感测单元（506B，508B）进行通信。