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    ORTHOVOLTAGE RADIOSURGERY
    5.
    发明申请
    ORTHOVOLTAGE RADIOSURGERY 审中-公开

    公开(公告)号：WO2008124801A3

    公开(公告)日：2008-12-31

    申请号：PCT/US2008059808

    申请日：2008-04-09

    Applicant: ORAYA THERAPEUTICS INC ,  GERTNER MICHAEL ,  HANSEN STEVEN D

    Inventor： GERTNER MICHAEL ,  HANSEN STEVEN D

    IPC: A61N5/10

    CPC classification number: A61N5/1067 ,  A61B6/506 ,  A61B6/508 ,  A61N5/10 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1019 ,  A61N2005/1022 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1091 ,  A61N2005/1097

    Abstract: A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, an eye is held with force and in alignment with the system. In some embodiments, the device automatically turns off with excessive movement outside of alignment along an axis of the eye. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

    Abstract translation: 描述了放射外科系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施方案中，身体的其它病症或组织用辐射剂量治疗。 在一些实施例中，目标组织基于眼睛成像被放置在全局坐标系中。 在一些实施例中，全局坐标系统内的目标组织导致基于坐标系统内的目标组织定向的自动定位系统的方向。 在一些实施例中，使用治疗计划，其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。 在一些实施方案中，使用基准标记来鉴定靶组织的位置。 在一些实施例中，眼睛被保持并且与系统对准。 在一些实施例中，设备沿着眼睛的轴线的对准内部的过度运动自动关闭。 在一些实施例中，描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其它治疗之前，之前或之后随同伴随地递送。

    DEVICES AND METHODS FOR TARGETED NASAL PHOTOTHERAPY
    6.
    发明申请
    DEVICES AND METHODS FOR TARGETED NASAL PHOTOTHERAPY 审中-公开
    用于靶向鼻部光动力治疗的装置和方法

    公开(公告)号：WO2007109496A8

    公开(公告)日：2008-05-15

    申请号：PCT/US2007064048

    申请日：2007-03-15

    Applicant: ALLUX MEDICAL INC ,  GERTNER MICHAEL ,  FLOM JAMES R ,  JOHNSON PETER L ,  LECLERC NORBERT H ,  ROGERS ERICA

    Inventor： GERTNER MICHAEL ,  FLOM JAMES R ,  JOHNSON PETER L ,  LECLERC NORBERT H ,  ROGERS ERICA

    IPC: A61N5/06

    CPC classification number: A61N5/0603 ,  A61N2005/0607 ,  A61N2005/063 ,  A61N2005/0644 ,  A61N2005/0647 ,  A61N2005/0652 ,  A61N2005/0654 ,  A61N2005/0661

    Abstract: The invention is directed to therapy devices for providing therapeutic light to a target region of tissue within a nasal cavity. The devices are adapted to include a light source communicating with a distal end of the first insertion member, wherein light from the light source illuminates a target region of tissue within a nasal cavity posterior to a limen nasi of the nasal cavity, and further wherein the insertion member is configured to prevent illumination of a region of tissue anterior to the limen nasi. The devices are further adapted to be positioned within the nasal cavity by a user without observing the location of the distal tip.

    Abstract translation: 本发明涉及用于向鼻腔内的组织的目标区域提供治疗光的治疗装置。 所述装置适于包括与第一插入构件的远端连通的光源，其中来自光源的光照射鼻腔内的鼻腔后方的鼻腔内的组织的目标区域，并且其中， 插入构件被构造成防止照亮莱茵前面的组织区域。 所述装置进一步适于在不观察远侧末端的位置的情况下由使用者定位在鼻腔内。

    OBESITY TREATMENT SYSTEMS
    7.
    发明申请
    OBESITY TREATMENT SYSTEMS 审中-公开
    肥胖治疗系统

    公开(公告)号：WO2007067206A2

    公开(公告)日：2007-06-14

    申请号：PCT/US2006015881

    申请日：2006-04-26

    Applicant: GERTNER MICHAEL

    Inventor： GERTNER MICHAEL

    IPC: A61B17/08

    CPC classification number: A61B17/0401 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/0469 ,  A61B17/0487 ,  A61B17/1114 ,  A61B17/29 ,  A61B17/3417 ,  A61B2017/00827 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/1135 ,  A61F5/0083 ,  A61F2002/044 ,  A61N1/36007

    Abstract: In one embodiment, a pressure sensing system is described which transmits data to a patient management system external to a patient. The pressure sensing system can rigidly couple to an implantable port or flexibly couple to an implantable port. In some embodiments, the pressure sensing system communicates with a hydraulic actuating system. In some embodiments, the pressure sensing system is implantable and comprises a circuit capable of wireless transmission through the skin of a patient to an external receiver which is part of a patient management system. A patient management system is described which receives up to date as well as historical data from the pressure sensing system and manages the these data in the context of a patient database. In some embodiments, an extragastric balloon is described in which the balloon is contoured to -..it ..i poi.jL?p o± the stomach nur not circumscribe the stomach. In some embodiments, electroactive polymers or nitinol structures are utilized to create restriction on the stomach in response to food boluses entering the stomach. In some embodiments, a nasogastric connector is described with two expandable structures translateable toward and away from one another so as to create pressure between two organ lumens when brought toward each other and fixed with respect to one another.

    Abstract translation: 在一个实施例中，描述了将数据发送到患者外部的患者管理系统的压力感测系统。 压力感测系统可以刚性地耦合到可植入端口或柔性地耦合到可植入端口。 在一些实施例中，压力感测系统与液压致动系统连通。 在一些实施例中，压力感测系统是可植入的并且包括能够通过患者皮肤的无线传输到作为患者管理系统的一部分的外部接收器的电路。 描述了一种患者管理系统，其从压力感测系统接收最新的历史数据以及历史数据，并在患者数据库的上下文中管理这些数据。 在一些实施例中，描述了一种胃外气囊，其中，气囊被轮廓化，以便胃不能胃部胃肠。 在一些实施方案中，电活性聚合物或镍钛诺结构用于响应于进入胃的食物推注而对胃产生限制。 在一些实施例中，描述了鼻胃连接器，其具有可向彼此平移和远离的两个可扩张结构，以便当彼此相向并相对于彼此固定时在两个器官腔之间产生压力。

    OCULAR RADIOSURGERY
    8.
    发明申请
    OCULAR RADIOSURGERY 审中-公开
    眼科放射科医师

    公开(公告)号：WO2008118198A3

    公开(公告)日：2009-02-19

    申请号：PCT/US2007081569

    申请日：2007-10-16

    Applicant: ORAYA THERAPEUTICS INC ,  GERTNER MICHAEL

    Inventor： GERTNER MICHAEL

    IPC: A61N5/10 ,  A61B5/00

    CPC classification number: A61N5/1049 ,  A61B6/506 ,  A61B2017/306 ,  A61F9/009 ,  A61N5/1017 ,  A61N5/103 ,  A61N2005/105 ,  A61N2005/1056 ,  A61N2005/1091

    Abstract: A radiosurgery system describes a therapeutic radiation delivery to a target structure in a patient. The radiosurgery system treats inflammatory ocular disorders; places ocular structures in a global coordinate system based on ocular imaging; automates ocular structures inside the global coordinate system to direction of a positioning system that is directed based on ocular structures within the coordinate system; tracks and relates the position of ocular structures to the status of the radiosurgery system; determines beam energy and direction and duration of time for treatment for a specific disease to be treated and/or structures to be avoided; tracks structure of an eye; holds and fixes the eye is in place; places a fiducial is on the eye to aid in positioning; positions the eye off the refelction; and combines with other treatments and can be delivered concomitant with, prior to, or following other treatments.

    Abstract translation: 放射外科系统描述了对患者的靶结构的治疗性辐射递送。 放射外科系统治疗炎症性眼部疾病; 将眼部结构置于基于眼睛成像的全局坐标系中; 将全局坐标系内的眼结构自动化到基于坐标系内眼睛结构的定位系统的方向; 跟踪并将眼部结构的位置与放射外科手术系统的状态相关联; 确定要治疗的特定疾病和/或要避免的结构的束能量和治疗时间的方向和持续时间; 轨道结构的眼睛; 保持和修复眼睛到位; 放置基准在眼睛上帮助定位; 将眼睛放在反光面上; 并结合其他治疗方法，并可在其他治疗之前，之前或之后进行交付。

    METHODS AND DEVICES FOR CHRONIC EMBOLIC PROTECTION
    9.
    发明申请
    METHODS AND DEVICES FOR CHRONIC EMBOLIC PROTECTION 审中-公开
    用于慢性栓塞保护的方法和装置

    公开(公告)号：WO2006055052A3

    公开(公告)日：2006-08-17

    申请号：PCT/US2005025021

    申请日：2005-07-14

    Applicant: GERTNER MICHAEL

    Inventor： GERTNER MICHAEL

    IPC: A61M25/01

    CPC classification number: A61F2/01 ,  A61F2002/018 ,  A61F2230/0019 ,  A61F2230/0069 ,  A61F2250/0023

    Abstract: A medical device for interposition between a first flow path and at least one second flow path is provided. The device includes a first surface facing toward the opening of at least one second flow path; and a second surface facing away from the opening of at least one second flow path. When the device is in the operative position, it extends less than the complete circumference of the first flow path and substantially covers the opening of at least one second flow path. The device contains one or more surface features to facilitate chronic implantation. The device further has one or more characteristic porosities. Different configurations are indicated depending on the pathophysiology being treated and dictate the characteristic porosity of the device. In some, cases blood is prevented from reaching the second flow path and in other cases, particulates traveling within the blood are prevented from reaching the second flow path.

    Abstract translation: 提供了用于插入第一流路和至少一个第二流路之间的医疗装置。 该装置包括面向至少一个第二流动路径的开口的第一表面; 以及远离至少一个第二流动路径的开口的第二表面。 当设备处于操作位置时，其延伸小于第一流动路径的整个圆周并且基本上覆盖至少一个第二流动路径的开口。 该装置包含一个或多个表面特征以便于慢性植入。 该装置还具有一个或多个特征孔隙率。 根据正在治疗的病理生理学来指示不同的构型，并且指示装置的特征孔隙率。 在一些情况下，防止血液到达第二流动路径，并且在其他情况下，防止在血液内行进的微粒到达第二流动路径。

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